Interaction between positive allosteric modulators and trapping blockers of the NMDA receptor channel

British Journal of Pharmacology

Volumn 172, Issue 5, 2015, Pages 1333-1347

  Emnett, Christine M ^a,b   Eisenman, Lawrence N ^b   Mohan, Jayaram ^b   Taylor, Amanda A ^b   Doherty, James J ^b   Paul, Steven M ^b   Zorumski, Charles F ^b,c,d   Mennerick, Steven ^b,c,d  

^a WASHINGTON UNIVERSITY   (United States)

^b WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c Sage Therapeutics Inc   (United States)

^d WEILL CORNELL MEDICAL COLLEGE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHOLESTEROL DERIVATIVE; KETAMINE; MEMANTINE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; N METHYL DEXTRO ASPARTIC ACID RECEPTOR BLOCKING AGENT; PREGNENOLONE SULFATE; SGE 201; UNCLASSIFIED DRUG; (DELTA5,6-3-OXYNORCHOLENYL)DIMETHYLCARBINOL; NORSTEROID; PREGNENOLONE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN ELECTROPHYSIOLOGY; BRAIN SLICE; CONTROLLED STUDY; DRUG MECHANISM; EXCITATORY POSTSYNAPTIC POTENTIAL; FEMALE; HIPPOCAMPUS; NERVE CELL MEMBRANE STEADY POTENTIAL; NERVE CELL NETWORK; NEUROPROTECTION; NONHUMAN; OOCYTE; PROTEIN FUNCTION; RAT; RECEPTOR BLOCKING; STEADY STATE; ALLOSTERISM; ANIMAL; ANTAGONISTS AND INHIBITORS; CELL CULTURE; CHEMISTRY; DOSE RESPONSE; DRUG EFFECTS; METABOLISM; STRUCTURE ACTIVITY RELATION;

ALLOSTERIC REGULATION; ANIMALS; CELLS, CULTURED; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; HYDROXYCHOLESTEROLS; NORSTEROIDS; PREGNENOLONE; RATS; RECEPTORS, N-METHYL-D-ASPARTATE; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84922802843     PISSN: 00071188     EISSN: 14765381     Source Type: Journal    
DOI: 10.1111/bph.13007     Document Type: Article

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