A cross-talk between Aβ and endothelial SSAO/VAP-1 accelerates vascular damage and Aβ aggregation related to CAA-AD

Neurobiology of Aging

Volumn 36, Issue 2, 2015, Pages 762-775

  Solé, Montse ^a   Miñano Molina, Alfredo J ^a,b   Unzeta, Mercedes ^a  

^a INSTITUT DE NEUROCIÈNCIES   (Spain)

^b CENTRO DE INVESTIGACIÓN BIOMÉDICA EN RED SOBRE ENFERMEDADES NEURODEGENERATIVAS CIBERNED   (Spain)

Author keywords

Alzheimer's disease; Amyloid beta aggregation; Cerebral amyloid angiopathy (CAA); Semicarbazide sensitive amine oxidase vascular adhesion protein 1 (SSAO VAP 1); Vascular damage

Indexed keywords

AMINE OXIDASE (COPPER CONTAINING); AMYLOID BETA PROTEIN; AMYLOID BETA PROTEIN[1-40]; AMYLOID BETA PROTEIN[1-42]; CASPASE 3; PROTEIN BAX; PROTEIN BCL 2; PROTEIN P53; VASCULAR ADHESION PROTEIN 1; ADVANCED GLYCATION END PRODUCT; AOC3 PROTEIN, HUMAN; CELL ADHESION MOLECULE;

ALZHEIMER DISEASE; APOPTOSIS; ARTICLE; BLOOD VESSEL INJURY; CELL DAMAGE; CELL MEMBRANE; CELL VIABILITY; CONTROLLED STUDY; CYTOTOXICITY; DISEASE ASSOCIATION; DISEASE COURSE; ENDOTHELIUM CELL; ENZYME ACTIVATION; ENZYME ACTIVITY; HUMAN; HUMAN CELL; IN VITRO STUDY; PROTEIN AGGREGATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; REAL TIME POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; SIMULATION; SMOOTH MUSCLE FIBER; VASCULAR AMYLOIDOSIS; CELL CULTURE; CEREBRAL AMYLOID ANGIOPATHY; GENE EXPRESSION; GENETICS; METABOLISM; MOLECULARLY TARGETED THERAPY; OXIDATIVE STRESS; PATHOLOGY; PHYSIOLOGY;

ALZHEIMER DISEASE; AMINE OXIDASE (COPPER-CONTAINING); AMYLOID BETA-PEPTIDES; APOPTOSIS; CELL ADHESION MOLECULES; CELLS, CULTURED; CEREBRAL AMYLOID ANGIOPATHY; ENDOTHELIAL CELLS; GENE EXPRESSION; GLYCOSYLATION END PRODUCTS, ADVANCED; HUMANS; MOLECULAR TARGETED THERAPY; OXIDATIVE STRESS;

EID: 84922797696     PISSN: 01974580     EISSN: 15581497     Source Type: Journal    
DOI: 10.1016/j.neurobiolaging.2014.09.030     Document Type: Article

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