High red blood cell nitric oxide synthase activation is not associated with improved vascular function and red blood cell deformability in sickle cell anaemia

British Journal of Haematology

Volumn 168, Issue 5, 2015, Pages 728-736

  Grau, Marijke ^a   Mozar, Anaïs ^b,c   Charlot, Keyne ^b,c   Lamarre, Yann ^b,c   Weyel, Linda ^a   Suhr, Frank ^a   Collins, Bianca ^a   Jumet, Stéphane ^b   Hardy Dessources, Marie Dominique ^b,c   Romana, Marc ^b,c   Lemonne, Nathalie ^d   Etienne Julan, Maryse ^b,c,d   Antoine Jonville, Sophie ^b   Bloch, Wilhelm ^a   Connes, Philippe ^b,c,e  

^a GERMAN SPORT UNIVERSITY COLOGNE   (Germany)

^b UNIVERSITÉ DES ANTILLES ET DE LA GUYANE   (France)

^c Laboratoire d'Excellence du Globule Rouge (LABEX GR Ex) PRES Sorbonne   (France)

^d Centre Hospitalier Universitaire Pointe a Pitre   (Guadeloupe)

^e INSTITUT UNIVERSITAIRE DE FRANCE   (France)

Author keywords

Blood rheology; Microcirculation; Nitric oxide synthase; Sickle cell anaemia

Indexed keywords

3 NITROTYROSINE; BETA SPECTRIN; FODRIN; NITRIC OXIDE SYNTHASE; NITRITE; PROTEIN KINASE B; SERINE; SPECTRIN; UNCLASSIFIED DRUG; 3-NITROTYROSINE; TYROSINE;

ARTICLE; BLOOD VESSEL FUNCTION; CONTROLLED STUDY; CYTOMETRY; DISEASE ASSOCIATION; EKTACYTOMETRY; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; ERYTHROCYTE; ERYTHROCYTE DEFORMABILITY; FEMALE; HUMAN; HUMAN CELL; HUMAN TISSUE; HYPERTHERMIA; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; LASER DOPPLER FLOWMETRY; MAJOR CLINICAL STUDY; MALE; MICROCIRCULATION; NITROSYLATION; SHEAR RATE; SICKLE CELL ANEMIA; ANALOGS AND DERIVATIVES; CLINICAL TRIAL; ENZYMOLOGY; METABOLISM; OXIDATIVE STRESS; PATHOLOGY; PHOSPHORYLATION;

ANEMIA, SICKLE CELL; ENZYME ACTIVATION; ERYTHROCYTE DEFORMABILITY; ERYTHROCYTES; FEMALE; HUMANS; MALE; NITRIC OXIDE SYNTHASE; OXIDATIVE STRESS; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-AKT; SPECTRIN; TYROSINE;

EID: 84922796095     PISSN: 00071048     EISSN: 13652141     Source Type: Journal    
DOI: 10.1111/bjh.13185     Document Type: Article

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