Postural vasoconstriction and leg ulceration in homozygous sickle cell disease

Clinical Science

Volumn 92, Issue 2, 1997, Pages 153-158

  Mohan, J S ^b,c   Marshall, J M ^b,c,d   Reid, H L ^b,c   Thomas, P W ^a   Serjeant, G R ^a  

^a Med Research Council Laboratories   (Jamaica)

^b UNIVERSITY OF THE WEST INDIES   (Jamaica)

^c UNIVERSITY OF BIRMINGHAM   (United Kingdom)

^d Medical School   (United Kingdom)

Author keywords

Homozygous sickle cell disease; Laser Doppler flowmetry; Posture; Ulcer

Indexed keywords

ARTICLE; BED REST; BLOOD VESSEL REACTIVITY; CLINICAL ARTICLE; CONTROLLED STUDY; ERYTHROCYTE; HOMOZYGOSITY; HUMAN; HUMAN CELL; LASER DOPPLER FLOWMETRY; LEG ULCER; MALE; PRIORITY JOURNAL; SCAR; SICKLE CELL ANEMIA; VASOCONSTRICTION;

EID: 0031020166     PISSN: 01435221     EISSN: None     Source Type: Journal    
DOI: 10.1042/cs0920153     Document Type: Article

References (18)

1. Serjeant GR. Sickle cell disease. Oxford: Oxford University Press.
2. Hassan AAK, Tooke JE. Mechanism of the postural vasoconstrictor response in the human foot. Clin Sci 1988; 75: 379-87.
3. Allen AJ, Wright DII, McCollum CN, Tooke JE. Impaired postural vasoconstriction: a contributory cause of oedema in patients with chronic venous insufficiency. Phlebology 1988; 3: 163-8.
4. Rayman G, Hassan AAK, Tooke JE. Blood flow in the skin of the foot related to posture in diabetes mellitus. Br Med J 1986; 292: 87-90.
5. Gniadecka M, Gniadecki R, Serup J, Sondergaard J. Microvascular reactions to postural changes in patients with sickle cell anaemia. Acta Derm Venerol 1994; 74: 191-3.
6. Hassan AAK, Carter G, Tooke JE. Postural vasoconstriction in the human foot during the menstrual cycle. J Physiol (London) 1987; 382: 44P.
7. Mohan J, Marshall JM, Reid HL, Serjeant GR. Daily variability in resting levels of cardiovascular variables in normal subject and in those with homozygous sickle cell disease. Clin Auton Res 1995; 5: 1-6.
8. Mohan J, Marshall JM, Serjeant GR. Skin microcirculation and leg ulcers in subjects with homozygous sickle cell disease, Int J Microcirc Clin Exp 1995; 15: 204.
9. Stevens MCG, Maude GH, Cupidore L, Jackson H, Hayes RJ, Serjeant GR. Prepubertal growth and skeletal maturation in sickle cell disease. Pediatrics 1986; 78: 124-32.
10. Nilsson GE, Tenland J, Oberg PA Evaluation of a laser-Doppler flowmeter for measurement of tissue blood flow. IEEE Trans Biomed Eng 1980; 10: 957.
11. Barnett NJ, Dougherty G, Pettinger SJ. Comparative study of two laser Doppler blood flowmeters. J Med Eng Tech 1990; 14: 243-9.
12. Imholtz BPM, Settels JJ, van der Meiracker AH, Wesseling KH, Wieling W. Non-invasive continuous finger blood pressure measurement during orthostatic stress compared to intra-arterial pressure. Cardiovasc Res 1990; 24: 214-21.
13. Betke K, Marti HR, Schlicht I. Estimation of small percentages of fetal haemoglobin. Nature (London) 1959; 184: 1877-8.
14. Maxwell SE, Delaney HD. Designing experiments and analysing data. Belmont, CA, U.S.A.: Wadsworth Publishing Company, 1990.
15. Mohan J, Marshall JM. A comparative study in subjects with homozygous sickle cell disease and in normal subjects of responses evoked in forearm vasculature by mild, indirect cooling. Clin Auton Res 1994; 4: 35-40.
16. Serjeant GR. Ulcers in haematological disorders. In: Westerhof W, ed. Leg ulcers: diagnosis and treatment: Amsterdam: Elsevier Science Publishers, 1993: 199-211.
17. Serjeant GR. Leg ulceration in sickle cell anaemia. Arch Intern Med 1974; 133: 690-4.
18. Koshy M, Entsuah R, Koranda A, et al. Leg ulcers in patients with sickle cell disease. Blood 1989; 74: 1403-8.