Red fluorescent zinc oxide nanoparticle: A novel platform for cancer targeting

ACS Applied Materials and Interfaces

Volumn 7, Issue 5, 2015, Pages 3373-3381

  Hong, Hao ^a   Wang, Fei ^b   Zhang, Yin ^c   Graves, Stephen A ^c   Eddine, Savo Bou Zein ^a,d   Yang, Yunan ^a   Theuer, Charles P ^e   Nickles, Robert J ^c   Wang, Xudong ^b   Cai, Weibo ^a,c,f  

^a UNIVERSITY OF WISCONSIN MADISON   (United States)

^b University of Wisconsin Madison   (United States)

^c UNIVERSITY OF WISCONSIN SCHOOL OF MEDICINE AND PUBLIC HEALTH   (United States)

^d AMERICAN UNIVERSITY OF BEIRUT   (Lebanon)

^e TRACON Pharmaceuticals   (United States)

^f UNIVERSITY OF WISCONSIN   (United States)

Author keywords

angiogenesis; CD105; drug delivery; imaging; positron emission tomography; zinc oxide

Indexed keywords

COPPER COMPOUNDS; DISEASES; DRUG DELIVERY; FLUORESCENCE IMAGING; II-VI SEMICONDUCTORS; IMAGING TECHNIQUES; MAMMALS; MONOCLONAL ANTIBODIES; NANOPARTICLES; OXIDE MINERALS; POSITRONS; TARGETED DRUG DELIVERY; THERANOSTICS; TUMORS; ZINC OXIDE; ZNO NANOPARTICLES;

ANGIOGENESIS; CD105; DUAL-MODALITY IMAGING; MULTI-MODALITY IMAGING; POSITRON EMISSION TOMOGRAPHY (PET); SURFACE ENGINEERING; TUMOR IMAGING AGENTS; ZINC OXIDE NANOPARTICLES;

POSITRON EMISSION TOMOGRAPHY;

COPPER; FLUORESCENT DYE; METAL NANOPARTICLE; MONOCLONAL ANTIBODY; NANOCAPSULE; RADIOPHARMACEUTICAL AGENT; TRC105; ZINC OXIDE;

ANIMAL; BAGG ALBINO MOUSE; BREAST TUMOR; CHEMISTRY; FEMALE; FLUORESCENCE MICROSCOPY; METABOLISM; MOUSE; MULTIMODAL IMAGING; PATHOLOGY; POSITRON EMISSION TOMOGRAPHY; PROCEDURES; SCINTISCANNING; TUMOR CELL LINE; ULTRASTRUCTURE;

ANIMALS; ANTIBODIES, MONOCLONAL; BREAST NEOPLASMS; CELL LINE, TUMOR; COPPER RADIOISOTOPES; FEMALE; FLUORESCENT DYES; METAL NANOPARTICLES; MICE; MICE, INBRED BALB C; MICROSCOPY, FLUORESCENCE; MULTIMODAL IMAGING; NANOCAPSULES; POSITRON-EMISSION TOMOGRAPHY; RADIOPHARMACEUTICALS; ZINC OXIDE;

EID: 84922773614     PISSN: 19448244     EISSN: 19448252     Source Type: Journal    
DOI: 10.1021/am508440j     Document Type: Article

References (39)

1. Xiong, H. M. ZnO Nanoparticles Applied to Bioimaging and Drug Delivery Adv. Mater. 2013, 25, 5329-5335
2. Zhang, Y.; Nayak, T. R.; Hong, H.; Cai, W. Biomedical Applications of Zinc Oxide Nanomaterials Curr. Mol. Med. 2013, 13, 1633-1645
3. Ko, W.; Jung, N.; Lee, M.; Yun, M.; Jeon, S. Electronic Nose Based on Multipatterns of ZnO Nanorods on a Quartz Resonator with Remote Electrodes ACS Nano 2013, 7, 6685-6690
4. Liu, D.; Wu, W.; Qiu, Y.; Yang, S.; Xiao, S.; Wang, Q. Q.; Ding, L.; Wang, J. Surface Functionalization of ZnO Nanotetrapods with Photoactive and Electroactive Organic Monolayers Langmuir 2008, 24, 5052-5059
5. Mankoff, D. A. A Definition of Molecular Imaging J. Nucl. Med. 2007, 48, 18N-21N
6. Moriyama, E. H.; Zheng, G.; Wilson, B. C. Optical Molecular Imaging: from Single Cell to Patient Clin. Pharmacol. Ther. 2008, 84, 267-271
7. Cai, W.; Chen, X. Multimodality Molecular Imaging of Tumor Angiogenesis J. Nucl. Med. 2008, 49 (Suppl 2) 113S-128S
8. Lopci, E.; Grassi, I.; Chiti, A.; Nanni, C.; Cicoria, G.; Toschi, L.; Fonti, C.; Lodi, F.; Mattioli, S.; Fanti, S. PET Radiopharmaceuticals for Imaging of Tumor Hypoxia: A Review of the Evidence Am. J. Nucl. Med. Mol. Imaging 2014, 4, 365-384
9. Chakravarty, R.; Hong, H.; Cai, W. Positron Emission Tomography Image-Guided Drug Delivery: Current Status and Future Perspectives. Mol. Pharm. 2014.
10. Dallas, N. A.; Samuel, S.; Xia, L.; Fan, F.; Gray, M. J.; Lim, S. J.; Ellis, L. M. Endoglin (CD105): a Marker of Tumor Vasculature and Potential Target for Therapy Clin. Cancer Res. 2008, 14, 1931-1937
11. Seon, B. K.; Haba, A.; Matsuno, F.; Takahashi, N.; Tsujie, M.; She, X.; Harada, N.; Uneda, S.; Tsujie, T.; Toi, H.; Tsai, H.; Haruta, Y. Endoglin-Targeted Cancer Therapy Curr. Drug Delivery 2011, 8, 135-143
12. 66Ga-Labeled Monoclonal Antibody Mol. Pharmaceutics 2012, 9, 1441-1448
13. Hong, H.; Yang, K.; Zhang, Y.; Engle, J. W.; Feng, L.; Yang, Y.; Nayak, T. R.; Goel, S.; Bean, J.; Theuer, C. P.; Barnhart, T. E.; Liu, Z.; Cai, W. In Vivo Targeting and Imaging of Tumor Vasculature with Radiolabeled, Antibody-Conjugated Nanographene ACS Nano 2012, 6, 2361-2370
14. 66Ga-Labeled Nano-graphene Biomaterials 2012, 33, 4147-4156
15. 64Cu-Labeled Monoclonal Antibody: NOTA is Superior to DOTA PLoS One 2011, 6, e28005
16. Guo, J.; Hong, H.; Chen, G.; Shi, S.; Zheng, Q.; Zhang, Y.; Theuer, C. P.; Barnhart, T. E.; Cai, W.; Gong, S. Image-Guided and Tumor-Targeted Drug Delivery with Radiolabeled Unimolecular Micelles Biomaterials 2013, 34, 8323-8332
17. 89Zr and IRDye 800CW Mol. Pharmaceutics 2012, 9, 2339-2349
18. Rosen, L. S.; Hurwitz, H. I.; Wong, M. K.; Goldman, J.; Mendelson, D. S.; Figg, W. D.; Spencer, S.; Adams, B. J.; Alvarez, D.; Seon, B. K.; Theuer, C. P.; Leigh, B. R.; Gordon, M. S. A Phase I First-in-human Study of TRC105 (Anti-Endoglin Antibody) in Patients with Advanced Cancer Clin. Cancer Res. 2012, 18, 4820-4829
19. Shi, H. Y.; Deng, B.; Zhong, S. L.; Wang, L.; Xu, A. W. Synthesis of Zinc Oxide Nanoparticles with Strong, Tunable and Stable Visible Light Emission by Solid-State Transformation of Zn(II)-Organic Coordination Polymers J. Mater. Chem. 2011, 21, 12309-12315
20. Hong, H.; Shi, J.; Yang, Y.; Zhang, Y.; Engle, J. W.; Nickles, R. J.; Wang, X.; Cai, W. Cancer-Targeted Optical Imaging with Fluorescent Zinc Oxide Nanowires Nano Lett. 2011, 11, 3744-3750
21. Shi, J.; Hong, H.; Ding, Y.; Yang, Y.; Cai, W.; Wang, X. Evolution of Zinc Oxide Nanostructures through Kinetics Control J. Mater. Chem. 2011, 21, 9000-9008
22. Hong, H.; Yang, Y.; Zhang, Y.; Engle, J. W.; Barnhart, T. E.; Nickles, R. J.; Leigh, B. R.; Cai, W. Positron Emission Tomography Imaging of CD105 Expression During Tumor Angiogenesis Eur. J. Nucl. Med. Mol. Imaging 2011, 38, 1335-1343
23. Xiao, Y.; Hong, H.; Javadi, A.; Engle, J. W.; Xu, W.; Yang, Y.; Zhang, Y.; Barnhart, T. E.; Cai, W.; Gong, S. Multifunctional Unimolecular Micelles for Cancer-Targeted Drug Delivery and Positron Emission Tomography Imaging Biomaterials 2012, 33, 3071-3082
24. Shi, S.; Yang, K.; Hong, H.; Valdovinos, H. F.; Nayak, T. R.; Zhang, Y.; Theuer, C. P.; Barnhart, T. E.; Liu, Z.; Cai, W. Tumor Vasculature Targeting and Imaging in Living Mice with Reduced Graphene Oxide Biomaterials 2013, 34, 3002-3009
25. 64Cu-Labeled Superparamagnetic Iron Oxide Nanoparticles for Targeted Anticancer Drug Delivery and PET/MR Imaging Biomaterials 2011, 32, 4151-4160
26. Zhou, J.; Xu, N. S.; Wang, Z. L. Dissolving Behavior and Stability of ZnO Wires in Biofluids: A Study on Biodegradability and Biocompatibility of ZnO Nanostructures Adv. Mater. 2006, 18, 2432-2435
27. Taratula, O.; Galoppini, E.; Wang, D.; Chu, D.; Zhang, Z.; Chen, H.; Saraf, G.; Lu, Y. Binding Studies of Molecular Linkers to ZnO and MgZnO Nanotip Films J. Phys. Chem. B 2006, 110, 6506-6515
28. Lin, H. Y.; Cheng, C. L.; Chou, Y. Y.; Huang, L. L.; Chen, Y. F.; Tsen, K. T. Enhancement of Band Gap Emission Stimulated by Defect Loss Opt. Express 2006, 14, 2372-2379
29. Gong, Y.; Andelman, T.; Neumark, G.; OBrien, S.; Kuskovsky, I. Origin of Defect-Related Green Emission from ZnO Nanoparticles: Effect of Surface Modification Nanoscale Res. Lett. 2007, 2, 297-302
30. Tang, X.; Choo, E. S. G.; Li, L.; Ding, J.; Xue, J. Synthesis of ZnO Nanoparticles with Tunable Emission Colors and Their Cell Labeling Applications Chem. Mater. 2010, 22, 3383-3388
31. Zhang, Y.; Yang, Y.; Hong, H.; Cai, W. Multimodality Molecular Imaging of CD105 (Endoglin) Expression Int. J. Clin. Exp. Med. 2011, 4, 32-42
32. Gambhir, S. S. Molecular Imaging of Cancer with Positron Emission Tomography Nat. Rev. Cancer 2002, 2, 683-693
33. 18F-Based Radiotracers Am. J. Nucl. Med. Mol. Imaging 2012, 2, 55-76
34. 11C-acetate Am. J. Nucl. Med. Mol. Imaging 2012, 2, 33-47
35. Fakhri, G. E. Ready for Prime Time? Dual Tracer PET and SPECT Imaging Am. J. Nucl. Med. Mol. Imaging 2012, 2, 415-417
36. Nolting, D. D.; Nickels, M. L.; Guo, N.; Pham, W. Molecular Imaging Probe Development: a Chemistry Perspective Am. J. Nucl. Med. Mol. Imaging 2012, 2, 273-306
37. van Dongen, G. A.; Ussi, A. E.; de Man, F. H.; Migliaccio, G. EATRIS, a European Initiative to Boost Translational Biomedical Research Am. J. Nucl. Med. Mol. Imaging 2013, 3, 166-174
38. Roy, R.; Das, M.; Dwivedi, P. D. Toxicological Mode of Action of ZnO Nanoparticles: Impact on Immune Cells Mol. Immunol. 2015, 63, 184-192
39. Ravetch, J. V.; Bolland, S. IgG Fc Receptors Annu. Rev. Immunol. 2001, 19, 275-290