Hop-derived prenylflavonoids are substrates and inhibitors of the efflux transporter breast cancer resistance protein (BCRP/ABCG2)

Molecular Nutrition and Food Research

Volumn 58, Issue 11, 2014, Pages 2099-2110

  Tan, Kee W ^a,b,c   Cooney, Janine ^a   Jensen, Dwayne ^a   Li, Yan ^d   Paxton, James W ^c   Birch, Nigel P ^b,e   Scheepens, Arjan ^a  

^a THE NEW ZEALAND INSTITUTE FOR PLANT AND FOOD RESEARCH LIMITED   (New Zealand)

^b UNIVERSITY OF AUCKLAND   (New Zealand)

^c THE UNIVERSITY OF AUCKLAND   (New Zealand)

^d AUCKLAND UNIVERSITY OF TECHNOLOGY   (New Zealand)

^e UNIVERSITY OF AUCKLAND   (New Zealand)

Author keywords

ABC transporter; ABCG2; Bioavailability; Herb drug interaction; Multidrug resistance; Prenylflavonoid

Indexed keywords

HUMULUS; HUMULUS LUPULUS;

6-PRENYLNARINGENIN; 8-PRENYLNARINGENIN; ABC TRANSPORTER; ABCG2 PROTEIN, HUMAN; ANTINEOPLASTIC AGENT; CARRIER PROTEIN; FLAVANONE DERIVATIVE; FLAVONOID; ISOXANTHOHUMOL; MITOXANTRONE; PHYTOESTROGEN; PROPIOPHENONE DERIVATIVE; TUMOR PROTEIN; XANTHOHUMOL; XANTHONE DERIVATIVE; XENOBIOTIC AGENT;

ANTAGONISTS AND INHIBITORS; BIOAVAILABILITY; BREAST TUMOR; CHEMISTRY; DRUG RESISTANCE; FEMALE; GENE EXPRESSION REGULATION; GENETICS; HEK293 CELL LINE; HERB DRUG INTERACTION; HUMAN; HUMULUS; METABOLISM;

ANTINEOPLASTIC AGENTS; ATP-BINDING CASSETTE TRANSPORTERS; BIOLOGICAL AVAILABILITY; BREAST NEOPLASMS; DRUG RESISTANCE, NEOPLASM; FEMALE; FLAVANONES; FLAVONOIDS; GENE EXPRESSION REGULATION, NEOPLASTIC; HEK293 CELLS; HERB-DRUG INTERACTIONS; HUMANS; HUMULUS; MEMBRANE TRANSPORT PROTEINS; MITOXANTRONE; NEOPLASM PROTEINS; PHYTOESTROGENS; PROPIOPHENONES; XANTHONES; XENOBIOTICS;

EID: 84922772731     PISSN: 16134125     EISSN: 16134133     Source Type: Journal    
DOI: 10.1002/mnfr.201400288     Document Type: Article

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