Defective lymphoid organogenesis underlies the immune deficiency caused by a heterozygous S32I mutation in IκBα

Journal of Experimental Medicine

Volumn 212, Issue 2, 2015, Pages 185-202

  Mooster, Jana L ^a,b   Bras, Severine Le ^a,b   Massaad, Michel J ^a,b   Jabara, Haifa ^a,b   Yoon, Juhan ^a,b   Galand, Claire ^a,b   Heesters, Balthasar A ^a,c   Burton, Oliver T ^a,b   Mattoo, Hamid ^d   Manis, John ^b   Geha, Raif S ^a,b  

^a BOSTON CHILDREN S HOSPITAL   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

^c UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^d MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELL ADHESION MOLECULE; GENOMIC DNA; I KAPPA B ALPHA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LYMPHOTOXIN BETA RECEPTOR; PROTEIN; S32I PROTEIN; UNCLASSIFIED DRUG; CODON; I KAPPA B; NF-KAPPAB INHIBITOR ALPHA; TOLL LIKE RECEPTOR; TUMOR NECROSIS FACTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTACT ALLERGY; DEGRADATION; FOLLICULAR DENDRITIC CELL; GENE MUTATION; GENE TARGETING; HETEROZYGOTE; HUMAN; IMMUNE DEFICIENCY; LYMPH NODE; LYMPHOID ORGAN; MOUSE; NONHUMAN; ORGANOGENESIS; PEYER PATCH; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; ANIMAL; ANTIBODY PRODUCTION; B LYMPHOCYTE; CODON; CONTACT DERMATITIS; DELAYED HYPERSENSITIVITY; DISEASE MODEL; EMBRYOLOGY; GENETICS; IMMUNOLOGIC DEFICIENCY SYNDROMES; IMMUNOLOGY; LYMPHOID TISSUE; METABOLISM; MUTATION; PHOSPHORYLATION; PROTEIN DEGRADATION; T LYMPHOCYTE SUBPOPULATION; TRANSGENIC MOUSE;

ANIMALS; ANTIBODY FORMATION; B-LYMPHOCYTES; CODON; DERMATITIS, CONTACT; DISEASE MODELS, ANIMAL; HETEROZYGOTE; HYPERSENSITIVITY, DELAYED; I-KAPPA B PROTEINS; IMMUNOLOGIC DEFICIENCY SYNDROMES; LYMPHOID TISSUE; MICE; MICE, TRANSGENIC; MUTATION; ORGANOGENESIS; PHOSPHORYLATION; PROTEOLYSIS; T-LYMPHOCYTE SUBSETS; TOLL-LIKE RECEPTORS; TUMOR NECROSIS FACTORS;

EID: 84922759100     PISSN: 00221007     EISSN: 15409538     Source Type: Journal    
DOI: 10.1084/jem.20140979     Document Type: Article

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