Cdc42 interacting protein 4 (CIP4) is essential for integrin-dependent T-cell trafficking

Proceedings of the National Academy of Sciences of the United States of America

Volumn 107, Issue 37, 2010, Pages 16252-16256

  Koduru, Suresh ^a   Kumar, Lalit ^a   Massaad, Michel J ^a   Ramesh, Narayanaswamy ^a   Le Bras, Séverine ^a   Ozcan, Esra ^a   Oyoshi, Michiko K ^a   Kaku, Mayumi ^a   Fujiwara, Yuko ^a   Kremer, Leonor ^b   King, Sandra ^c   Fuhlbrigge, Robert ^a,c   Rodig, Scott ^c   Sage, Peter ^d   Carman, Chris ^d   Alcaide, Pilar ^c   Luscinskas, Francis W ^c   Geha, Raif S ^a,e  

^a BOSTON CHILDREN S HOSPITAL   (United States)

^b CENTRO NACIONAL DE BIOTECNOLOGÍA   (Spain)

^c BRIGHAM AND WOMEN S HOSPITAL   (United States)

^d BETH ISRAEL DEACONESS MEDICAL CENTER   (United States)

^e HARVARD MEDICAL SCHOOL   (United States)

Author keywords

Adhesion; Antigen response; Contact hypersensitivity; F BAR; Inflammation

Indexed keywords

CD40 ANTIGEN; CD40 LIGAND; CDC42 INTERACTING PROTEIN 4; F ACTIN; HAPTEN; IMMUNOGLOBULIN G; INTEGRIN; INTERCELLULAR ADHESION MOLECULE 1; NEURAL WISKOTT ALDRICH SYNDROME PROTEIN; OVALBUMIN; PROTEIN; PROTEIN CDC42; UNCLASSIFIED DRUG; VASCULAR CELL ADHESION MOLECULE 1; WISKOTT ALDRICH SYNDROME PROTEIN; MICROTUBULE ASSOCIATED PROTEIN; TRIP10 PROTEIN, MOUSE;

ADOPTIVE TRANSFER; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIBODY AFFINITY; ANTIBODY PRODUCTION; ARTICLE; B LYMPHOCYTE; CD4+ T LYMPHOCYTE; CELL ADHESION; CELL CYCLE ARREST; CELL MATURATION; CONTACT ALLERGY; CONTROLLED STUDY; EFFECTOR CELL; ENDOTHELIUM CELL; GERMINAL CENTER; LYMPHOCYTE MIGRATION; MONOLAYER CULTURE; MOUSE; NONHUMAN; POLARIZATION; PRIORITY JOURNAL; PROTEIN IMMOBILIZATION; SHEAR FLOW; T LYMPHOCYTE; T LYMPHOCYTE ACTIVATION; ANIMAL; C57BL MOUSE; CELL MOTION; CELL POLARITY; CYTOLOGY; DEFICIENCY; GENETICS; IMMUNOLOGY; KNOCKOUT MOUSE; LYMPHOCYTE ACTIVATION; SKIN ALLERGY;

MURINAE; MUS;

ANIMALS; B-LYMPHOCYTES; CELL ADHESION; CELL MOVEMENT; CELL POLARITY; DERMATITIS, ALLERGIC CONTACT; INTEGRINS; INTERCELLULAR ADHESION MOLECULE-1; LYMPHOCYTE ACTIVATION; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICROTUBULE-ASSOCIATED PROTEINS; T-LYMPHOCYTES; VASCULAR CELL ADHESION MOLECULE-1;

EID: 77957986989     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1002747107     Document Type: Article

References (29)

1. Heath RJ, Insall RH (2008) F-BAR domains: Multifunctional regulators of membrane curvature. J Cell Sci 121:1951-1954. (Pubitemid 352015191)
2. Aspenström P (1997) A Cdc42 target protein with homology to the non-kinase domain of FER has a potential role in regulating the actin cytoskeleton. Curr Biol 7: 479-487.
3. Tian L, Nelson DL, Stewart DM (2000) Cdc42-interacting protein 4 mediates binding of the Wiskott-Aldrich syndrome protein to microtubules. J Biol Chem 275:7854-7861.
4. Zimmerberg J, Kozlov MM (2006) How proteins produce cellular membrane curvature. Nat Rev Mol Cell Biol 7:9-19.
5. Hu J, et al. (2009) F-BAR-containing adaptor CIP4 localizes to early endosomes and regulates epidermal growth factor receptor trafficking and downregulation. Cell Signal 21:1686-1697.
6. Feng Y, et al. (2010) The Cdc42 interacting protein 4 (CIP4) gene knockout mouse reveals delayed and decreased endocytosis. J Biol Chem 285:4348-4354.
7. Linder S, Hüfner K, Wintergerst U, Aepfelbacher M (2000) Microtubule-dependent formation of podosomal adhesion structures in primary human macrophages. J Cell Sci 113:4165-4176. (Pubitemid 32000684)
8. von Andrian UH, Mackay CR (2000) T-cell function and migration. Two sides of the same coin. N Engl J Med 343:1020-1034.
9. Carman CV, et al. (2007) Transcellular diapedesis is initiated by invasive podosomes. Immunity 26:784-797.
10. MacLennan IC (2005) Germinal centers still hold secrets. Immunity 22:656-657.
11. Gorbachev AV, Fairchild RL (2001) Regulatory role of CD4+ T cells during the development of contact hypersensitivity responses. Immunol Res 24:69-77.
12. Park EJ, et al. (2007) Aberrant activation of integrin alpha4beta7 suppresses lymphocyte migration to the gut. J Clin Invest 117:2526-2538.
13. King C (2009) New insights into the differentiation and function of T follicular helper cells. Nat Rev Immunol 9:757-766.
14. Ochs HD, Nonoyama S, Farrington ML, Fischer SH, & Aruffo A (1993) The role of adhesion molecules in the regulation of antibody responses. Semin Hematol 30 (4 Suppl 4):72-79.
15. Cannons JL, et al. (2010) Optimal Germinal Center Responses Require A Multistage T Cell:B Cell Adhesion Process Involving Integrins, SLAM-Associated Protein, and CD84 (Immunity).
16. Scheynius A, Camp RL, Puré E (1996) Unresponsiveness to 2,4-dinitro-1-fluoro-benzene after treatment with monoclonal antibodies to leukocyte function-associated molecule-1 and intercellular adhesion molecule-1 during sensitization. J Immunol 156: 1804-1809. (Pubitemid 26072555)
17. Zhang H, et al. (2006) Impaired integrin-dependent function in Wiskott-Aldrich syndrome protein-deficient murine and human neutrophils. Immunity 25:285-295.
18. Tsuboi S, Nonoyama S, Ochs HD (2006) Wiskott-Aldrich syndrome protein is involved in alphaIIb beta3-mediated cell adhesion. EMBO Rep 7:506-511.
19. Deakin NO, et al. (2009) An integrin-alpha4-14-3-3zeta-paxillin ternary complex mediates localised Cdc42 activity and accelerates cell migration. J Cell Sci 122: 1654-1664.
20. Vicente-Manzanares M, Choi CK, Horwitz AR (2009) Integrins in cell migration - the actin connection. J Cell Sci 122:199-206.
21. Tsuboi S, et al. (2009) FBP17 mediates a common molecular step in the formation of podosomes and phagocytic cups in macrophages. J Biol Chem 284:8548-8556.
22. Carman CV (2009) Mechanisms for transcellular diapedesis: Probing and pathfinding by 'invadosome-like protrusions'. J Cell Sci 122:3025-3035.
23. Evans R, et al. (2009) Integrins in immunity. J Cell Sci 122:215-225.
24. Snapper SB, et al. (1998) Wiskott-Aldrich syndrome protein-deficient mice reveal a role for WASP in T but not B cell activation. Immunity 9:81-91.
25. Jabara H, et al. (2002) The binding site for TRAF2 and TRAF3 but not for TRAF6 is essential for CD40-mediated immunoglobulin class switching. Immunity 17:265-276. (Pubitemid 35279548)
26. Martin SF, et al. (2008) Toll-like receptor and IL-12 signaling control susceptibility to contact hypersensitivity. J Exp Med 205:2151-2162.
27. McLachlan JB, Catron DM, Moon JJ, Jenkins MK (2009) Dendritic cell antigen presentation drives simultaneous cytokine production by effector and regulatory T cells in inflamed skin. Immunity 30:277-288.
28. Alcaide P, et al. (2007) The 130-kDa glycoform of CD43 functions as an E-selectin ligand for activated Th1 cells in vitro and in delayed-type hypersensitivity reactions in vivo. J Invest Dermatol 127:1964-1972. (Pubitemid 47075363)
29. Lim YC, et al. (2003) Heterogeneity of endothelial cells from different organ sites in T-cell subset recruitment. Am J Pathol 162:1591-1601.