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Volumn 21, Issue 7, 2015, Pages 2030-2039

Negative impact of bone-marrow-derived mesenchymal stem cells on dextran sulfate sodium-induced colitis

Author keywords

Crohn's disease; Dextran sulfate sodium; Inflammatory bowel disease; Mesenchymal stem cells; Ulcerative colitis

Indexed keywords

DEXTRAN SULFATE; INTERLEUKIN 10; INTERLEUKIN 17; INTERLEUKIN 6; TRANSFORMING GROWTH FACTOR BETA; AUTACOID; CYTOKINE;

EID: 84922727033     PISSN: 10079327     EISSN: 22192840     Source Type: Journal    
DOI: 10.3748/wjg.v21.i7.2030     Document Type: Article
Times cited : (20)

References (49)
  • 1
    • 44349124113 scopus 로고    scopus 로고
    • The genetics and immunopathogenesis of inflammatory bowel disease
    • PMID: 18500230
    • Cho JH. The genetics and immunopathogenesis of inflammatory bowel disease. Nat Rev Immunol 2008; 8: 458-466 [PMID: 18500230 DOI: 10.1038/nri2340]
    • (2008) Nat Rev Immunol , vol.8 , pp. 458-466
    • Cho, J.H.1
  • 2
    • 34547176642 scopus 로고    scopus 로고
    • Unravelling the pathogenesis of inflammatory bowel disease
    • PMID: 17653185
    • Xavier RJ, Podolsky DK. Unravelling the pathogenesis of inflammatory bowel disease. Nature 2007; 448: 427-434 [PMID: 17653185 DOI: 10.1038/nature06005]
    • (2007) Nature , vol.448 , pp. 427-434
    • Xavier, R.J.1    Podolsky, D.K.2
  • 4
    • 0016792130 scopus 로고
    • Ultrastructure of L-phase variants isolated from a culture of Mycobacterium phlei
    • PMID: 1177288
    • Imaeda T. Ultrastructure of L-phase variants isolated from a culture of Mycobacterium phlei. J Med Microbiol 1975; 8: 389-395 [PMID: 1177288]
    • (1975) J Med Microbiol , vol.8 , pp. 389-395
    • Imaeda, T.1
  • 5
    • 36249021493 scopus 로고    scopus 로고
    • Concise review: Mesenchymal stem/multipotent stromal cells: The state of transdifferentiation and modes of tissue repair - Current views
    • PMID: 17901396
    • Phinney DG, Prockop DJ. Concise review: mesenchymal stem/multipotent stromal cells: the state of transdifferentiation and modes of tissue repair - current views. Stem Cells 2007; 25: 2896-2902 [PMID: 17901396 DOI: 10.1634/stemcells.2007-0637]
    • (2007) Stem Cells , vol.25 , pp. 2896-2902
    • Phinney, D.G.1    Prockop, D.J.2
  • 8
    • 79751504754 scopus 로고    scopus 로고
    • Mesenchymal stem cells: Mechanisms of inflammation
    • PMID: 21073342
    • Singer NG, Caplan AI. Mesenchymal stem cells: mechanisms of inflammation. Annu Rev Pathol 2011; 6: 457-478 [PMID: 21073342 DOI: 10.1146/annurev-pathol-011110-130230]
    • (2011) Annu Rev Pathol , vol.6 , pp. 457-478
    • Singer, N.G.1    Caplan, A.I.2
  • 9
    • 77954242073 scopus 로고    scopus 로고
    • Targeting improves MSC treatment of inflammatory bowel disease
    • PMID: 20389289
    • Ko IK, Kim BG, Awadallah A, Mikulan J, Lin P, Letterio JJ, Dennis JE. Targeting improves MSC treatment of inflammatory bowel disease. Mol Ther 2010; 18: 1365-1372 [PMID: 20389289 DOI: 10.1038/mt.2010.54]
    • (2010) Mol Ther , vol.18 , pp. 1365-1372
    • Ko, I.K.1    Kim, B.G.2    Awadallah, A.3    Mikulan, J.4    Lin, P.5    Letterio, J.J.6    Dennis, J.E.7
  • 10
    • 84871638604 scopus 로고    scopus 로고
    • Systemic infusion of bone marrow-derived mesenchymal stem cells for treatment of experimental colitis in mice
    • PMID: 22752635
    • He XW, He XS, Lian L, Wu XJ, Lan P. Systemic infusion of bone marrow-derived mesenchymal stem cells for treatment of experimental colitis in mice. Dig Dis Sci 2012; 57: 3136-3144 [PMID: 22752635 DOI: 10.1007/s10620-012-2290-5]
    • (2012) Dig Dis Sci , vol.57 , pp. 3136-3144
    • He, X.W.1    He, X.S.2    Lian, L.3    Wu, X.J.4    Lan, P.5
  • 11
    • 84864142890 scopus 로고    scopus 로고
    • Delivery of IL-12p40 ameliorates DSS-induced colitis by suppressing IL-17A expression and inflammation in the intestinal mucosa
    • PMID: 22836084
    • Kim DJ, Kim KS, Song MY, Seo SH, Kim SJ, Yang BG, Jang MH, Sung YC. Delivery of IL-12p40 ameliorates DSS-induced colitis by suppressing IL-17A expression and inflammation in the intestinal mucosa. Clin Immunol 2012; 144: 190-199 [PMID: 22836084 DOI: 10.1016/j.clim.2012.06.009]
    • (2012) Clin Immunol , vol.144 , pp. 190-199
    • Kim, D.J.1    Kim, K.S.2    Song, M.Y.3    Seo, S.H.4    Kim, S.J.5    Yang, B.G.6    Jang, M.H.7    Sung, Y.C.8
  • 13
    • 84874356143 scopus 로고    scopus 로고
    • Autologous adipose tissue-derived stem cells for the treatment of Crohn's fistula: A phase I clinical study
    • PMID: 23006344
    • Cho YB, Lee WY, Park KJ, Kim M, Yoo HW, Yu CS. Autologous adipose tissue-derived stem cells for the treatment of Crohn's fistula: a phase I clinical study. Cell Transplant 2013; 22: 279-285 [PMID: 23006344 DOI: 10.3727/096368912X656045]
    • (2013) Cell Transplant , vol.22 , pp. 279-285
    • Cho, Y.B.1    Lee, W.Y.2    Park, K.J.3    Kim, M.4    Yoo, H.W.5    Yu, C.S.6
  • 15
    • 84879459518 scopus 로고    scopus 로고
    • Expanded allogeneic adipose-derived stem cells (eASCs) for the treatment of complex perianal fistula in Crohn's disease: Results from a multicenter phase I/IIa clinical trial
    • PMID: 23053677
    • de la Portilla F, Alba F, García-Olmo D, Herrerías JM, González FX, Galindo A. Expanded allogeneic adipose-derived stem cells (eASCs) for the treatment of complex perianal fistula in Crohn's disease: results from a multicenter phase I/IIa clinical trial. Int J Colorectal Dis 2013; 28: 313-323 [PMID: 23053677 DOI: 10.1007/s00384-012-1581-9]
    • (2013) Int J Colorectal Dis , vol.28 , pp. 313-323
    • De La Portilla, F.1    Alba, F.2    García-Olmo, D.3    Herrerías, J.M.4    González, F.X.5    Galindo, A.6
  • 16
    • 21644462655 scopus 로고    scopus 로고
    • A phase I clinical trial of the treatment of Crohn's fistula by adipose mesenchymal stem cell transplantation
    • PMID: 15933795
    • García-Olmo D, García-Arranz M, Herreros D, Pascual I, Peiro C, Rodríguez-Montes JA. A phase I clinical trial of the treatment of Crohn's fistula by adipose mesenchymal stem cell transplantation. Dis Colon Rectum 2005; 48: 1416-1423 [PMID: 15933795 DOI: 10.1007/s10350-005-0052-6]
    • (2005) Dis Colon Rectum , vol.48 , pp. 1416-1423
    • García-Olmo, D.1    García-Arranz, M.2    Herreros, D.3    Pascual, I.4    Peiro, C.5    Rodríguez-Montes, J.A.6
  • 18
    • 84862999811 scopus 로고    scopus 로고
    • Long-term follow-up of patients undergoing adipose-derived adult stem cell administration to treat complex perianal fistulas
    • PMID: 22065114
    • Guadalajara H, Herreros D, De-La-Quintana P, Trebol J, Garcia-Arranz M, Garcia-Olmo D. Long-term follow-up of patients undergoing adipose-derived adult stem cell administration to treat complex perianal fistulas. Int J Colorectal Dis 2012; 27: 595-600 [PMID: 22065114 DOI: 10.1007/s00384-011-1350-1]
    • (2012) Int J Colorectal Dis , vol.27 , pp. 595-600
    • Guadalajara, H.1    Herreros, D.2    De-La-Quintana, P.3    Trebol, J.4    Garcia-Arranz, M.5    Garcia-Olmo, D.6
  • 19
    • 84863683915 scopus 로고    scopus 로고
    • Autologous expanded adipose-derived stem cells for the treatment of complex cryptoglandular perianal fistulas: A phase III randomized clinical trial (FATT 1: Fistula Advanced Therapy Trial 1) and long-term evaluation
    • PMID: 22706128
    • Herreros MD, Garcia-Arranz M, Guadalajara H, De-La-Quintana P, Garcia-Olmo D. Autologous expanded adipose-derived stem cells for the treatment of complex cryptoglandular perianal fistulas: a phase III randomized clinical trial (FATT 1: fistula Advanced Therapy Trial 1) and long-term evaluation. Dis Colon Rectum 2012; 55: 762-772 [PMID: 22706128 DOI: 10.1097/DCR.0b013e318255364a]
    • (2012) Dis Colon Rectum , vol.55 , pp. 762-772
    • Herreros, M.D.1    Garcia-Arranz, M.2    Guadalajara, H.3    De-La-Quintana, P.4    Garcia-Olmo, D.5
  • 20
    • 84887040879 scopus 로고    scopus 로고
    • Autologous adipose tissue-derived stem cells treatment demonstrated favorable and sustainable therapeutic effect for Crohn's fistula
    • PMID: 23404825
    • Lee WY, Park KJ, Cho YB, Yoon SN, Song KH, Kim do S, Jung SH, Kim M, Yoo HW, Kim I, Ha H, Yu CS. Autologous adipose tissue-derived stem cells treatment demonstrated favorable and sustainable therapeutic effect for Crohn's fistula. Stem Cells 2013; 31: 2575-2581 [PMID: 23404825 DOI: 10.1002/stem.1357]
    • (2013) Stem Cells , vol.31 , pp. 2575-2581
    • Lee, W.Y.1    Park, K.J.2    Cho, Y.B.3    Yoon, S.N.4    Song, K.H.5    Kim Do, S.6    Jung, S.H.7    Kim, M.8    Yoo, H.W.9    Kim, I.10    Ha, H.11    Yu, C.S.12
  • 21
    • 78650085746 scopus 로고    scopus 로고
    • Noël D. IL-6-dependent PGE2 secretion by mesenchymal stem cells inhibits local inflammation in experimental arthritis
    • PMID: 21151872
    • Bouffi C, Bony C, Courties G, Jorgensen C, Noël D. IL-6-dependent PGE2 secretion by mesenchymal stem cells inhibits local inflammation in experimental arthritis. PLoS One 2010; 5: e14247 [PMID: 21151872 DOI: 10.1371/journal.pone.0014247]
    • (2010) PLoS One , vol.5 , pp. e14247
    • Bouffi, C.1    Bony, C.2    Courties, G.3    Jorgensen, C.4
  • 22
    • 74549151228 scopus 로고    scopus 로고
    • Flk-1+ mesenchymal stem cells aggravate collagen-induced arthritis by up-regulating interleukin-6
    • PMID: 20002448
    • Chen B, Hu J, Liao L, Sun Z, Han Q, Song Z, Zhao RC. Flk-1+ mesenchymal stem cells aggravate collagen-induced arthritis by up-regulating interleukin-6. Clin Exp Immunol 2010; 159: 292-302 [PMID: 20002448 DOI: 10.1111/j.1365-2249.2009.04069.x]
    • (2010) Clin Exp Immunol , vol.159 , pp. 292-302
    • Chen, B.1    Hu, J.2    Liao, L.3    Sun, Z.4    Han, Q.5    Song, Z.6    Zhao, R.C.7
  • 23
    • 65249161683 scopus 로고    scopus 로고
    • Treatment of experimental arthritis by inducing immune tolerance with human adipose-derived mesenchymal stem cells
    • PMID: 19333946
    • González MA, Gonzalez-Rey E, Rico L, Büscher D, Delgado M. Treatment of experimental arthritis by inducing immune tolerance with human adipose-derived mesenchymal stem cells. Arthritis Rheum 2009; 60: 1006-1019 [PMID: 19333946 DOI: 10.1002/art.24405]
    • (2009) Arthritis Rheum , vol.60 , pp. 1006-1019
    • González, M.A.1    Gonzalez-Rey, E.2    Rico, L.3    Büscher, D.4    Delgado, M.5
  • 25
    • 79958060173 scopus 로고    scopus 로고
    • Transforming growth factor β-transduced mesenchymal stem cells ameliorate experimental autoimmune arthritis through reciprocal regulation of Treg/Th17 cells and osteoclastogenesis
    • PMID: 21384335
    • Park MJ, Park HS, Cho ML, Oh HJ, Cho YG, Min SY, Chung BH, Lee JW, Kim HY, Cho SG. Transforming growth factor β-transduced mesenchymal stem cells ameliorate experimental autoimmune arthritis through reciprocal regulation of Treg/Th17 cells and osteoclastogenesis. Arthritis Rheum 2011; 63: 1668-1680 [PMID: 21384335 DOI: 10.1002/art.30326]
    • (2011) Arthritis Rheum , vol.63 , pp. 1668-1680
    • Park, M.J.1    Park, H.S.2    Cho, M.L.3    Oh, H.J.4    Cho, Y.G.5    Min, S.Y.6    Chung, B.H.7    Lee, J.W.8    Kim, H.Y.9    Cho, S.G.10
  • 26
    • 77649298684 scopus 로고    scopus 로고
    • Discrepancy between the in vitro and in vivo effects of murine mesenchymal stem cells on T-cell proliferation and collagen-induced arthritis
    • PMID: 20175883
    • Schurgers E, Kelchtermans H, Mitera T, Geboes L, Matthys P. Discrepancy between the in vitro and in vivo effects of murine mesenchymal stem cells on T-cell proliferation and collagen-induced arthritis. Arthritis Res Ther 2010; 12: R31 [PMID: 20175883 DOI: 10.1186/ar2939]
    • (2010) Arthritis Res Ther , vol.12 , pp. R31
    • Schurgers, E.1    Kelchtermans, H.2    Mitera, T.3    Geboes, L.4    Matthys, P.5
  • 27
    • 84881104041 scopus 로고    scopus 로고
    • The synergistic immunoregulatory effects of culture-expanded mesenchymal stromal cells and CD4(+)25(+)Foxp3+ regulatory T cells on skin allograft rejection
    • PMID: 23940676
    • Lee JH, Jeon EJ, Kim N, Nam YS, Im KI, Lim JY, Kim EJ, Cho ML, Han KT, Cho SG. The synergistic immunoregulatory effects of culture-expanded mesenchymal stromal cells and CD4(+)25(+)Foxp3+ regulatory T cells on skin allograft rejection. PLoS One 2013; 8: e70968 [PMID: 23940676 DOI: 10.1371/journal.pone.0070968]
    • (2013) PLoS One , vol.8 , pp. e70968
    • Lee, J.H.1    Jeon, E.J.2    Kim, N.3    Nam, Y.S.4    Im, K.I.5    Lim, J.Y.6    Kim, E.J.7    Cho, M.L.8    Han, K.T.9    Cho, S.G.10
  • 28
    • 84876190903 scopus 로고    scopus 로고
    • The potential use of mesenchymal stem cells in hematopoietic stem cell transplantation
    • PMID: 23306700
    • Kim EJ, Kim N, Cho SG. The potential use of mesenchymal stem cells in hematopoietic stem cell transplantation. Exp Mol Med 2013; 45: e2 [PMID: 23306700 DOI: 10.1038/emm.2013.2]
    • (2013) Exp Mol Med , vol.45 , pp. e2
    • Kim, E.J.1    Kim, N.2    Cho, S.G.3
  • 29
    • 0037093058 scopus 로고    scopus 로고
    • Human bone marrow stromal cells suppress T-lymphocyte proliferation induced by cellular or nonspecific mitogenic stimuli
    • PMID: 11986244
    • Di Nicola M, Carlo-Stella C, Magni M, Milanesi M, Longoni PD, Matteucci P, Grisanti S, Gianni AM. Human bone marrow stromal cells suppress T-lymphocyte proliferation induced by cellular or nonspecific mitogenic stimuli. Blood 2002; 99: 3838-3843 [PMID: 11986244]
    • (2002) Blood , vol.99 , pp. 3838-3843
    • Di Nicola, M.1    Carlo-Stella, C.2    Magni, M.3    Milanesi, M.4    Longoni, P.D.5    Matteucci, P.6    Grisanti, S.7    Gianni, A.M.8
  • 30
    • 61849123247 scopus 로고    scopus 로고
    • Cell contact, prostaglandin E(2) and transforming growth factor beta 1 play non-redundant roles in human mesenchymal stem cell induction of CD4+CD25(High) forkhead box P3+ regulatory T cells
    • PMID: 19210524
    • English K, Ryan JM, Tobin L, Murphy MJ, Barry FP, Mahon BP. Cell contact, prostaglandin E(2) and transforming growth factor beta 1 play non-redundant roles in human mesenchymal stem cell induction of CD4+CD25(High) forkhead box P3+ regulatory T cells. Clin Exp Immunol 2009; 156: 149-160 [PMID: 19210524 DOI: 10.1111/j.1365-2249.2009.03874.x]
    • (2009) Clin Exp Immunol , vol.156 , pp. 149-160
    • English, K.1    Ryan, J.M.2    Tobin, L.3    Murphy, M.J.4    Barry, F.P.5    Mahon, B.P.6
  • 31
    • 15944376184 scopus 로고    scopus 로고
    • Bone marrow mesenchymal stem cells induce division arrest anergy of activated T cells
    • PMID: 15591115
    • Glennie S, Soeiro I, Dyson PJ, Lam EW, Dazzi F. Bone marrow mesenchymal stem cells induce division arrest anergy of activated T cells. Blood 2005; 105: 2821-2827 [PMID: 15591115 DOI: 10.1182/blood-2004-09-3696]
    • (2005) Blood , vol.105 , pp. 2821-2827
    • Glennie, S.1    Soeiro, I.2    Dyson, P.J.3    Lam, E.W.4    Dazzi, F.5
  • 32
    • 33644799418 scopus 로고    scopus 로고
    • Interferon-gamma-stimulated marrow stromal cells: A new type of nonhematopoietic antigen-presenting cell
    • PMID: 16293599
    • Stagg J, Pommey S, Eliopoulos N, Galipeau J. Interferon-gamma-stimulated marrow stromal cells: a new type of nonhematopoietic antigen-presenting cell. Blood 2006; 107: 2570-2577 [PMID: 16293599 DOI: 10.1182/blood-2005-07-2793]
    • (2006) Blood , vol.107 , pp. 2570-2577
    • Stagg, J.1    Pommey, S.2    Eliopoulos, N.3    Galipeau, J.4
  • 33
    • 84883898505 scopus 로고    scopus 로고
    • Mesenchymal stem cells for the treatment and prevention of graft-versus-host disease: Experiments and practice
    • PMID: 23722500
    • Kim N, Im KI, Lim JY, Jeon EJ, Nam YS, Kim EJ, Cho SG. Mesenchymal stem cells for the treatment and prevention of graft-versus-host disease: experiments and practice. Ann Hematol 2013; 92: 1295-1308 [PMID: 23722500 DOI: 10.1007/s00277-013-1796-z]
    • (2013) Ann Hematol , vol.92 , pp. 1295-1308
    • Kim, N.1    Im, K.I.2    Lim, J.Y.3    Jeon, E.J.4    Nam, Y.S.5    Kim, E.J.6    Cho, S.G.7
  • 34
    • 85027926151 scopus 로고    scopus 로고
    • The immunomodulatory properties of mesenchymal stem cells
    • PMID: 21499984
    • Marigo I, Dazzi F. The immunomodulatory properties of mesenchymal stem cells. Semin Immunopathol 2011; 33: 593-602 [PMID: 21499984 DOI: 10.1007/s00281-011-0267-7]
    • (2011) Semin Immunopathol , vol.33 , pp. 593-602
    • Marigo, I.1    Dazzi, F.2
  • 35
    • 49649119417 scopus 로고    scopus 로고
    • Mesenchymal stem cells for graft-versus-host disease: Close encounters with T cells
    • PMID: 18493977
    • Dazzi F, Marelli-Berg FM. Mesenchymal stem cells for graft-versus-host disease: close encounters with T cells. Eur J Immunol 2008; 38: 1479-1482 [PMID: 18493977 DOI: 10.1002/eji.200838433]
    • (2008) Eur J Immunol , vol.38 , pp. 1479-1482
    • Dazzi, F.1    Marelli-Berg, F.M.2
  • 38
    • 47249155734 scopus 로고    scopus 로고
    • Mesenchymal stem cells overexpressing interleukin-10 attenuate collagen-induced arthritis in mice
    • PMID: 18713142
    • Choi JJ, Yoo SA, Park SJ, Kang YJ, Kim WU, Oh IH, Cho CS. Mesenchymal stem cells overexpressing interleukin-10 attenuate collagen-induced arthritis in mice. Clin Exp Immunol 2008; 153: 269-276 [PMID: 18713142 DOI: 10.1111/j.1365-2249.2008.03683.x]
    • (2008) Clin Exp Immunol , vol.153 , pp. 269-276
    • Choi, J.J.1    Yoo, S.A.2    Park, S.J.3    Kang, Y.J.4    Kim, W.U.5    Oh, I.H.6    Cho, C.S.7
  • 39
    • 18644370435 scopus 로고    scopus 로고
    • Noël D. Reversal of the immunosuppressive properties of mesenchymal stem cells by tumor necrosis factor alpha in collagen-induced arthritis
    • PMID: 15880818
    • Djouad F, Fritz V, Apparailly F, Louis-Plence P, Bony C, Sany J, Jorgensen C, Noël D. Reversal of the immunosuppressive properties of mesenchymal stem cells by tumor necrosis factor alpha in collagen-induced arthritis. Arthritis Rheum 2005; 52: 1595-1603 [PMID: 15880818 DOI: 10.1002/art.21012]
    • (2005) Arthritis Rheum , vol.52 , pp. 1595-1603
    • Djouad, F.1    Fritz, V.2    Apparailly, F.3    Louis-Plence, P.4    Bony, C.5    Sany, J.6    Jorgensen, C.7
  • 40
    • 84863228492 scopus 로고    scopus 로고
    • Bone marrow-derived and synovium-derived mesenchymal cells promote Th17 cell expansion and activation through caspase 1 activation: Contribution to the chronicity of rheumatoid arthritis
    • PMID: 22275154
    • Eljaafari A, Tartelin ML, Aissaoui H, Chevrel G, Osta B, Lavocat F, Miossec P. Bone marrow-derived and synovium-derived mesenchymal cells promote Th17 cell expansion and activation through caspase 1 activation: contribution to the chronicity of rheumatoid arthritis. Arthritis Rheum 2012; 64: 2147-2157 [PMID: 22275154 DOI: 10.1002/art.34391]
    • (2012) Arthritis Rheum , vol.64 , pp. 2147-2157
    • Eljaafari, A.1    Tartelin, M.L.2    Aissaoui, H.3    Chevrel, G.4    Osta, B.5    Lavocat, F.6    Miossec, P.7
  • 41
    • 70350536359 scopus 로고    scopus 로고
    • Fetal BM-derived mesenchymal stem cells promote the expansion of human Th17 cells, but inhibit the production of Th1 cells
    • PMID: 19637224
    • Guo Z, Zheng C, Chen Z, Gu D, Du W, Ge J, Han Z, Yang R. Fetal BM-derived mesenchymal stem cells promote the expansion of human Th17 cells, but inhibit the production of Th1 cells. Eur J Immunol 2009; 39: 2840-2849 [PMID: 19637224 DOI: 10.1002/eji.200839070]
    • (2009) Eur J Immunol , vol.39 , pp. 2840-2849
    • Guo, Z.1    Zheng, C.2    Chen, Z.3    Gu, D.4    Du, W.5    Ge, J.6    Han, Z.7    Yang, R.8
  • 42
    • 33646577466 scopus 로고    scopus 로고
    • Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells
    • PMID: 16648838
    • Bettelli E, Carrier Y, Gao W, Korn T, Strom TB, Oukka M, Weiner HL, Kuchroo VK. Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells. Nature 2006; 441: 235-238 [PMID: 16648838 DOI: 10.1038/nature04753]
    • (2006) Nature , vol.441 , pp. 235-238
    • Bettelli, E.1    Carrier, Y.2    Gao, W.3    Korn, T.4    Strom, T.B.5    Oukka, M.6    Weiner, H.L.7    Kuchroo, V.K.8
  • 44
    • 32244442562 scopus 로고    scopus 로고
    • TGFbeta in the context of an inflammatory cytokine milieu supports de novo differentiation of IL-17-producing T cells
    • PMID: 16473830
    • Veldhoen M, Hocking RJ, Atkins CJ, Locksley RM, Stockinger B. TGFbeta in the context of an inflammatory cytokine milieu supports de novo differentiation of IL-17-producing T cells. Immunity 2006; 24: 179-189 [PMID: 16473830 DOI: 10.1016/j.immuni.2006.01.001]
    • (2006) Immunity , vol.24 , pp. 179-189
    • Veldhoen, M.1    Hocking, R.J.2    Atkins, C.J.3    Locksley, R.M.4    Stockinger, B.5
  • 45
    • 84859406158 scopus 로고    scopus 로고
    • The role of mouse mesenchymal stem cells in differentiation of naive T-cells into anti-inflammatory regulatory T-cell or proinflammatory helper T-cell 17 population
    • PMID: 21663543
    • Svobodova E, Krulova M, Zajicova A, Pokorna K, Prochazkova J, Trosan P, Holan V. The role of mouse mesenchymal stem cells in differentiation of naive T-cells into anti-inflammatory regulatory T-cell or proinflammatory helper T-cell 17 population. Stem Cells Dev 2012; 21: 901-910 [PMID: 21663543 DOI: 10.1089/scd.2011.0157]
    • (2012) Stem Cells Dev , vol.21 , pp. 901-910
    • Svobodova, E.1    Krulova, M.2    Zajicova, A.3    Pokorna, K.4    Prochazkova, J.5    Trosan, P.6    Holan, V.7
  • 46
    • 84880396453 scopus 로고    scopus 로고
    • Clinical applications of mesenchymal stem cells
    • PMID: 23864795
    • Kim N, Cho SG. Clinical applications of mesenchymal stem cells. Korean J Intern Med 2013; 28: 387-402 [PMID: 23864795 DOI: 10.3904/kjim.2013.28.4.387]
    • (2013) Korean J Intern Med , vol.28 , pp. 387-402
    • Kim, N.1    Cho, S.G.2
  • 47
    • 84898917571 scopus 로고    scopus 로고
    • Combination cell therapy using mesenchymal stem cells and regulatory T-cells provides a synergistic immunomodulatory effect associated with reciprocal regulation of TH1/TH2 and th17/treg cells in a murine acute graft-versus-host disease model
    • PMID: 23452894
    • Lim JY, Park MJ, Im KI, Kim N, Jeon EJ, Kim EJ, Cho ML, Cho SG. Combination cell therapy using mesenchymal stem cells and regulatory T-cells provides a synergistic immunomodulatory effect associated with reciprocal regulation of TH1/TH2 and th17/treg cells in a murine acute graft-versus-host disease model. Cell Transplant 2014; 23: 703-714 [PMID: 23452894 DOI: 10.3727/096368913X664577]
    • (2014) Cell Transplant , vol.23 , pp. 703-714
    • Lim, J.Y.1    Park, M.J.2    Im, K.I.3    Kim, N.4    Jeon, E.J.5    Kim, E.J.6    Cho, M.L.7    Cho, S.G.8
  • 48
    • 84907912531 scopus 로고    scopus 로고
    • Induction of mixed chimerism using combinatory cell-based immune modulation with mesenchymal stem cells and regulatory T cells for solid-organ transplant tolerance
    • PMID: 24804993
    • Im KI, Park MJ, Kim N, Lim JY, Park HS, Lee SH, Nam YS, Lee ES, Lee JH, Cho ML, Cho SG. Induction of mixed chimerism using combinatory cell-based immune modulation with mesenchymal stem cells and regulatory T cells for solid-organ transplant tolerance. Stem Cells Dev 2014; 23: 2364-2376 [PMID: 24804993 DOI: 10.1089/scd.2013.0617]
    • (2014) Stem Cells Dev , vol.23 , pp. 2364-2376
    • Im, K.I.1    Park, M.J.2    Kim, N.3    Lim, J.Y.4    Park, H.S.5    Lee, S.H.6    Nam, Y.S.7    Lee, E.S.8    Lee, J.H.9    Cho, M.L.10    Cho, S.G.11
  • 49
    • 60449093316 scopus 로고    scopus 로고
    • Human adult stem cells derived from adipose tissue protect against experimental colitis and sepsis
    • PMID: 19136511
    • Gonzalez-Rey E, Anderson P, González MA, Rico L, Büscher D, Delgado M. Human adult stem cells derived from adipose tissue protect against experimental colitis and sepsis. Gut 2009; 58: 929-939 [PMID: 19136511 DOI: 10.1136/gut.2008.168534]
    • (2009) Gut , vol.58 , pp. 929-939
    • Gonzalez-Rey, E.1    Anderson, P.2    González, M.A.3    Rico, L.4    Büscher, D.5    Delgado, M.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.