P53 at the endoplasmic reticulum regulates apoptosis in a Ca2+-dependent manner

Proceedings of the National Academy of Sciences of the United States of America

Volumn 112, Issue 6, 2015, Pages 1779-1784

  Giorgi, Carlotta ^a   Bonora, Massimo ^a   Sorrentino, Giovanni ^b   Missiroli, Sonia ^a   Poletti, Federica ^a   Suski, Jan M ^c   Ramirez, Fabian Galindo ^d,e   Rizzuto, Rosario ^d   Virgilio, Francesco Di ^a   Zito, Ester ^f   Pandolfi, Pier Paolo ^g,h   Wieckowski, Mariusz R ^c   Mammano, Fabio ^d,e   Sal, Giannino Del ^b,h   Pinton, Paolo ^a  

^a UNIVERSITY OF FERRARA   (Italy)

^b Laborotorio Nazionale Consorzio Interuniversitario Biotecnologie AREA Science Park   (Italy)

^c NENCKI INSTITUTE OF EXPERIMENTAL BIOLOGY   (Poland)

^d UNIVERSITY OF PADOVA   (Italy)

^e VENETIAN INSTITUTE OF MOLECULAR MEDICINE   (Italy)

^f MARIO NEGRI INSTITUTE FOR PHARMACOLOGICAL RESEARCH   (Italy)

^g HARVARD MEDICAL SCHOOL   (United States)

^h UNIVERSITY OF TRIESTE   (Italy)

Author keywords

Apoptosis; Calcium; Endoplasmic reticulum; Mitochondria associated membranes; P53

Indexed keywords

ADENOSINE TRIPHOSPHATASE; AEQUORIN; CALCIUM; CALCIUM ION; CASPASE 3; DOXORUBICIN; FURA 2; PROMYELOCYTIC LEUKEMIA PROTEIN; PROTEIN P53; REGULATOR PROTEIN; SARCOPLASMIC RETICULUM CALCIUM TRANSPORTING ADENOSINE TRIPHOSPHATASE;

ANIMAL; ANIMAL CELL; APOPTOSIS; ARTICLE; BIOACCUMULATION; CALCIUM HOMEOSTASIS; CALCIUM SIGNALING; CALCIUM TRANSPORT; CELL DEATH; CELL FRACTIONATION; CELL INTERACTION; CELL LINE; CELLULAR DISTRIBUTION; CYTOPLASM; CYTOSOL; CYTOSOLIC FRACTION; DOWN REGULATION; ENDOPLASMIC RETICULUM; FEMALE; FIBROBLAST; FLOW CYTOMETRY; FLUORESCENCE RESONANCE ENERGY TRANSFER; GENE SILENCING; GENETICS; HCT116 CELL LINE; HELA CELL LINE; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE; IMMUNOPRECIPITATION; IN VITRO STUDY; IN VIVO STUDY; METABOLISM; MISSENSE MUTATION; MITOCHONDRIAL MEMBRANE; MITOCHONDRION; MOUSE; NONHUMAN; OXIDATION REDUCTION STATE; OXIDATIVE STRESS; PHYSIOLOGY; PRIORITY JOURNAL; PROTEIN CLEAVAGE; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PROCESSING; WESTERN BLOTTING;

AEQUORIN; ANIMALS; APOPTOSIS; BLOTTING, WESTERN; CALCIUM; CELL LINE; CYTOSOL; ENDOPLASMIC RETICULUM; FLOW CYTOMETRY; FLUORESCENCE RESONANCE ENERGY TRANSFER; FURA-2; GENE KNOCKDOWN TECHNIQUES; GENETICS; HUMANS; IMMUNOPRECIPITATION; METABOLISM; MICE; MITOCHONDRIA; PHYSIOLOGY; SARCOPLASMIC RETICULUM CALCIUM-TRANSPORTING ATPASES; TUMOR SUPPRESSOR PROTEIN P53;

EID: 84922675574     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1410723112     Document Type: Article

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