Synthesis and in vitro anticancer activity evaluation of novel bioreversible phosphate inositol derivatives

European Journal of Medicinal Chemistry

Volumn 93, Issue , 2015, Pages 172-181

  Chen, Wenbin ^a   Deng, Zhaohui ^a   Chen, Kuangyu ^a   Dou, Daolei ^a   Song, Fanbo ^a   Li, Luyuan ^a   Xi, Zhen ^a  

^a NANKAI UNIVERSITY   (China)

Author keywords

4 Acyloxybenzyl; Anticancer; Bioreversible protection; Phosphate inositol

Indexed keywords

CISPLATIN; DIHYDROXYL INOSITOL; INOSITOL; INOSITOL PHOSPHATE; POLYPHOSPHOINOSITIDE; TRIHYDROXYL INOSITOL; UNCLASSIFIED DRUG; ANTINEOPLASTIC AGENT;

A549 CELL LINE; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL LINE; CANCER INHIBITION; DRUG CYTOTOXICITY; DRUG DESIGN; DRUG STRUCTURE; DRUG SYNTHESIS; HELA CELL LINE; HUMAN; HUMAN CELL; IN VITRO STUDY; LUNG CANCER; SIGNAL TRANSDUCTION; CELL PROLIFERATION; CELL SURVIVAL; CHEMICAL STRUCTURE; CHEMISTRY; DOSE RESPONSE; DRUG EFFECTS; STRUCTURE ACTIVITY RELATION; SYNTHESIS; TUMOR CELL LINE;

ANTINEOPLASTIC AGENTS; CELL LINE, TUMOR; CELL PROLIFERATION; CELL SURVIVAL; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG DESIGN; HUMANS; INOSITOL PHOSPHATES; MOLECULAR STRUCTURE; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84922667645     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2015.01.064     Document Type: Article

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