Activation of AMPK attenuates lipopolysaccharide-impaired integrity and function of blood-brain barrier in human brain microvascular endothelial cells

Experimental and Molecular Pathology

Volumn 97, Issue 3, 2014, Pages 386-392

  Zhao, Zhihong ^a   Hu, Jue ^b   Gao, Xiaoping ^a   Liang, Hui ^a   Liu, Zhan ^a  

^a HUNAN NORMAL UNIVERSITY   (China)

^b CHANGSHA CENTRAL HOSPITAL   (China)

Author keywords

Aging; AMPK; BBB; LPS; NAD(P)H oxidase; ROS

Indexed keywords

5 AMINO 4 IMIDAZOLE CARBOXAMIDE RIBOSIDE; ADENOVIRUS VECTOR; APOCYNIN; CLAUDIN 5; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; IMIDAZOLE DERIVATIVE; LIPOPOLYSACCHARIDE; OCCLUDIN; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; SUPEROXIDE DISMUTASE; UNCLASSIFIED DRUG;

ARTICLE; BLOOD BRAIN BARRIER; BRAIN CELL; BRAIN MICROVASCULAR ENDOTHELIAL CELL; CAPILLARY ENDOTHELIAL CELL; ENZYME ACTIVATION; ENZYME INHIBITION; GAIN OF FUNCTION MUTATION; HUMAN; HUMAN CELL; LONG TERM EXPOSURE; PERMEABILITY; PROTEIN EXPRESSION; PROTEIN SUBUNIT; SEPSIS; TIGHT JUNCTION; UPREGULATION; CAPILLARY PERMEABILITY; CELL CULTURE; CHEMICALLY INDUCED; ENDOTHELIUM CELL; ENZYMOLOGY; FLUORESCENT ANTIBODY TECHNIQUE; METABOLISM; PATHOLOGY; PHYSIOLOGY; WESTERN BLOTTING;

AMP-ACTIVATED PROTEIN KINASES; BLOOD-BRAIN BARRIER; BLOTTING, WESTERN; CAPILLARY PERMEABILITY; CELLS, CULTURED; ENDOTHELIAL CELLS; ENZYME ACTIVATION; FLUORESCENT ANTIBODY TECHNIQUE; HUMANS; LIPOPOLYSACCHARIDES; NADPH OXIDASE; REACTIVE OXYGEN SPECIES; SEPSIS;

EID: 84922661560     PISSN: 00144800     EISSN: 10960945     Source Type: Journal    
DOI: 10.1016/j.yexmp.2014.09.006     Document Type: Article

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