In vivo activation of AMP-activated protein kinase attenuates diabetes-enhanced degradation of GTP cyclohydrolase I

Diabetes

Volumn 58, Issue 8, 2009, Pages 1893-1901

  Wang, Shuangxi ^a   Xu, Jian ^a   Song, Ping ^a   Viollet, Benoit ^b,c,d   Zou, Ming Hui ^a  

^a UNIVERSITY OF OKLAHOMA COLLEGE OF MEDICINE   (United States)

^b INSTITUT COCHIN   (France)

^c UNIVERSITÉ PARIS DESCARTES   (France)

^d INSERM   (France)

Author keywords

[No Author keywords available]

Indexed keywords

5 AMINO 4 IMIDAZOLECARBOXAMIDE RIBOSIDE; ACETYLCHOLINE; ADENYLATE KINASE; BENZYLOXYCARBONYLLEUCYLLEUCYLLEUCINAL; BIOPTERIN; GUANOSINE TRIPHOSPHATE CYCLOHYDROLASE I; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; MESSENGER RNA; METFORMIN; PROTEASOME; SEPIAPTERIN; STREPTOZOCIN; TETRAHYDROBIOPTERIN; THREONINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; AORTA; ARTICLE; CELL LINE; CONTROLLED STUDY; DIABETES MELLITUS; ENDOTHELIAL DYSFUNCTION; ENDOTHELIUM CELL; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; HUMAN; HUMAN CELL; IN VIVO STUDY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; UMBILICAL VEIN;

AMP-ACTIVATED PROTEIN KINASES; ANIMALS; DIABETES MELLITUS, EXPERIMENTAL; ENDOTHELIUM, VASCULAR; ENZYME ACTIVATION; GENES, REPORTER; GTP CYCLOHYDROLASE; HUMANS; MICE; TRANSFECTION; UMBILICAL VEINS; VASODILATION;

EID: 68049129864     PISSN: 00121797     EISSN: 1939327X     Source Type: Journal    
DOI: 10.2337/db09-0267     Document Type: Article

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