A high-throughput LC-MS/MS assay for quantification of artesunate and its metabolite dihydroartemisinin in human plasma and saliva

Bioanalysis

Volumn 6, Issue 18, 2014, Pages 2357-2369

  Birgersson, Sofia ^a   Ericsson, Therese ^a   Blank, Antje ^b   Hagens, Cornelia Von ^b   Ashton, Michael ^a   Hoffmann, Kurt Jürgen ^a  

^a UNIVERSITY OF GOTHENBURG   (Sweden)

^b UNIVERSITY HOSPITAL HEIDELBERG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ARTESUNATE; DIHYDROARTEMISININ; ARTEMISININ DERIVATIVE;

ARTICLE; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG DETERMINATION; DRUG ELIMINATION; DRUG GLUCURONIDATION; DRUG HALF LIFE; DRUG SALIVA LEVEL; DRUG SELECTIVITY; DRUG SENSITIVITY; DRUG STABILITY; HIGH THROUGHPUT SCREENING; HUMAN; HYDROLYSIS; LIQUID CHROMATOGRAPHY; PROCESS OPTIMIZATION; SALIVA ANALYSIS; SINGLE DRUG DOSE; TANDEM MASS SPECTROMETRY; THERMOSTABILITY; VALIDATION PROCESS; ANALYSIS; BLOOD; BLOOD ANALYSIS; CALIBRATION; CHEMISTRY; METABOLISM; PROCEDURES; SALIVA; STEREOISOMERISM; TEMPERATURE; TIME;

ANALYTIC SAMPLE PREPARATION METHODS; ARTEMISININS; BLOOD CHEMICAL ANALYSIS; CALIBRATION; CHROMATOGRAPHY, LIQUID; DRUG STABILITY; HUMANS; SALIVA; STEREOISOMERISM; TANDEM MASS SPECTROMETRY; TEMPERATURE; TIME FACTORS;

EID: 84922646045     PISSN: 17576180     EISSN: 17576199     Source Type: Journal    
DOI: 10.4155/bio.14.116     Document Type: Article

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