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Volumn 816, Issue 1-2, 2005, Pages 233-242
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Development and validation of a high-performance liquid chromatography-mass spectroscopy assay for determination of artesunate and dihydroartemisinin in human plasma
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Author keywords
Antimalarial; Antiparasitic; Artesunate; Dihydroartemisinin; Liquid chromatography mass spectroscopy
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Indexed keywords
ACETIC ACID;
ATMOSPHERIC PRESSURE;
CONCENTRATION (PROCESS);
EXTRACTION;
HIGH PERFORMANCE LIQUID CHROMATOGRAPHY;
IONIZATION;
MASS SPECTROMETRY;
METABOLISM;
METHANOL;
MIXTURES;
POSITIVE IONS;
ATMOSPHERIC PRESSURE CHEMICAL IONIZATION (APCI);
DIHYDROARTEMISININ (DHA);
HUMAN PLASMA;
SOLID PHASE EXTRACTION (SPE);
BIOMEDICAL ENGINEERING;
ACETIC ACID;
ACETONITRILE;
ALPHA DIHYDROARTEMISININ;
ARTEMISIN;
ARTESUNATE;
BETA DIHYDROARTEMISININ;
DIHYDROARTEMISININ DERIVATIVE;
DRUG METABOLITE;
ION;
METHANOL;
UNCLASSIFIED DRUG;
ACCURACY;
ARTICLE;
BLOOD SAMPLING;
COLUMN CHROMATOGRAPHY;
CONTROLLED STUDY;
DRUG BLOOD LEVEL;
DRUG DETERMINATION;
DRUG RETENTION;
DRUG SENSITIVITY;
DRUG SYNTHESIS;
FLOW RATE;
HIGH PERFORMANCE LIQUID CHROMATOGRAPHY;
HUMAN;
ION MONITORING;
ION PAIR CHROMATOGRAPHY;
LINEAR SYSTEM;
MASS SPECTROMETRY;
NORMAL HUMAN;
PRIORITY JOURNAL;
QUALITY CONTROL;
RELIABILITY;
SOLID PHASE EXTRACTION;
STANDARD;
VALIDATION PROCESS;
ANTIMALARIALS;
ARTEMISININS;
CHROMATOGRAPHY, HIGH PRESSURE LIQUID;
DRUG STABILITY;
FREEZING;
HUMANS;
MASS SPECTROMETRY;
REPRODUCIBILITY OF RESULTS;
SESQUITERPENES;
ARTESUNATE;
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EID: 12444261827
PISSN: 15700232
EISSN: None
Source Type: Journal
DOI: 10.1016/j.jchromb.2004.11.042 Document Type: Article |
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Times cited : (75)
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References (10)
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