Hydrocortisone prevents immunosuppression by interleukin-10+ natural killer cells after trauma-hemorrhage

Critical Care Medicine

Volumn 42, Issue 12, 2014, Pages e752-e761

  Roquilly, Antoine ^a,b   Broquet, Alexis ^a   Jacqueline, Cédric ^a   Masson, Damien ^c   Segain, Jean Pierre ^b   Braudeau, Cecile ^b,d   Vourc'h, Mickael ^a,b   Caillon, Jocelyne ^a   Altare, Frédéric ^a   Josien, Regis ^b,d   Retière, Christelle ^a   Villadangos, Jose ^e,f   Asehnoune, Karim ^a,b  

^a UNIVERSITÉ DE NANTES   (France)

^b NANTES UNIVERSITY HOSPITAL   (France)

^c HÔTEL DIEU   (France)

^d Centre National de la Recherche Scientifique   (France)

^e UNIVERSITY OF SOUTH AUSTRALIA   (Australia)

^f UNIVERSITY OF MELBOURNE   (Australia)

Author keywords

Dendritic cells; Hydrocortisone; Interleukin 10; Natural killer cells; Pneumonia; Trauma

Indexed keywords

GLUCOCORTICOID INDUCED TUMOR NECROSIS FACTOR RECEPTOR; HYDROCORTISONE; INTERLEUKIN 10; INTERLEUKIN 12; INTERLEUKIN 17; INTERLEUKIN 6; PLACEBO; TUMOR NECROSIS FACTOR ALPHA; ANTIINFLAMMATORY AGENT; CYTOKINE;

ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL INTERACTION; CONTROLLED STUDY; DENDRITIC CELL; DRUG MECHANISM; DRUG RESPONSE; EXPERIMENTAL STUDY; FEMALE; HUMAN; IMMUNE DEFICIENCY; IMMUNOMODULATION; MALE; MOUSE; MULTICENTER STUDY (TOPIC); NATURAL KILLER CELL; NONHUMAN; PNEUMONIA; POST TREATMENT SURVIVAL; POSTTRAUMATIC COMPLICATION; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; RANDOMIZED CONTROLLED TRIAL (TOPIC); UPREGULATION; ADOLESCENT; AGED; ANIMAL; CLINICAL TRIAL; CROSS INFECTION; DOSE RESPONSE; IMMUNOLOGY; INJURY; INJURY SCALE; MIDDLE AGED; MULTICENTER STUDY; PATHOPHYSIOLOGY; PNEUMONIA, BACTERIAL; RANDOMIZED CONTROLLED TRIAL; STAPHYLOCOCCAL INFECTIONS; YOUNG ADULT;

ADOLESCENT; ADULT; AGED; ANIMALS; ANTI-INFLAMMATORY AGENTS; CROSS INFECTION; CYTOKINES; DENDRITIC CELLS; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; HUMANS; HYDROCORTISONE; INTERLEUKIN-10; KILLER CELLS, NATURAL; MALE; MICE; MIDDLE AGED; PNEUMONIA, BACTERIAL; STAPHYLOCOCCAL INFECTIONS; TRAUMA SEVERITY INDICES; WOUNDS AND INJURIES; YOUNG ADULT;

EID: 84922580179     PISSN: 00903493     EISSN: 15300293     Source Type: Journal    
DOI: 10.1097/CCM.0000000000000658     Document Type: Article

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