Deficiency of antigen-specific B cells results in decreased Trypanosoma cruzi systemic but not mucosal immunity due to CD8 T cell exhaustion

Journal of Immunology

Volumn 194, Issue 4, 2015, Pages 1806-1818

  Sullivan, Nicole L ^a,c   Eickhoff, Christopher S ^a   Sagartz, John ^b   Hoft, Daniel F ^a  

^a SAINT LOUIS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b S LOUIS UNIV HLTH SCIENCES CENTER   (United States)

^c EMORY UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELL PROTEIN; PROGRAMMED DEATH 1 RECEPTOR; PROTEIN LAG 3; SIALIDASE; TRANS SIALIDASE; UNCLASSIFIED DRUG; PROTOZOAL VACCINE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIGEN SPECIFICITY; ARTICLE; B LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELL STRESS; CHAGAS DISEASE; CONTROLLED STUDY; EFFECTOR CELL; FEMALE; INFECTION PREVENTION; MOUSE; MUCOSAL IMMUNITY; NONHUMAN; PARASITE IMMUNITY; PARASITE LOAD; PARASITEMIA; PASSIVE IMMUNIZATION; PROTEIN EXPRESSION; TRYPANOSOMA CRUZI; ADOPTIVE TRANSFER; ANIMAL; BAGG ALBINO MOUSE; ENZYME LINKED IMMUNOSORBENT ASSAY; FLOW CYTOMETRY; IMMUNOLOGY; KNOCKOUT MOUSE; LYMPHOCYTE ACTIVATION; SCID MOUSE; VACCINATION;

ADOPTIVE TRANSFER; ANIMALS; B-LYMPHOCYTES; CD8-POSITIVE T-LYMPHOCYTES; CHAGAS DISEASE; ENZYME-LINKED IMMUNOSORBENT ASSAY; FLOW CYTOMETRY; IMMUNITY, MUCOSAL; LYMPHOCYTE ACTIVATION; MICE; MICE, INBRED BALB C; MICE, KNOCKOUT; MICE, SCID; PROTOZOAN VACCINES; TRYPANOSOMA CRUZI; VACCINATION;

EID: 84922569783     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1303163     Document Type: Article

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