메뉴 건너뛰기




Volumn 398, Issue 1, 2015, Pages 1-10

Differential pleiotropy and HOX functional organization

Author keywords

Differential pleiotropy; Ensemble mediated allostery; Evolution and development; Functional domain structure; HOX; SLiMs; Transcription factors

Indexed keywords

GALACTOSE; HOMEOTIC SELECTOR PROTEIN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR GAL4; UNCLASSIFIED DRUG; DROSOPHILA PROTEIN; HOMEODOMAIN PROTEIN; PEPTIDE;

EID: 84922534892     PISSN: 00121606     EISSN: 1095564X     Source Type: Journal    
DOI: 10.1016/j.ydbio.2014.11.001     Document Type: Review
Times cited : (16)

References (79)
  • 1
    • 0344741332 scopus 로고    scopus 로고
    • Low-level ectopic expression of Fushi tarazu in Drosophila melanogaster results in ftz (Ual/Rpl)-like phenotypes and rescues ftz phenotypes
    • Argiropoulos B., Ho J., Blachuta B.J., Tayyab I., Percival-Smith A. Low-level ectopic expression of Fushi tarazu in Drosophila melanogaster results in ftz (Ual/Rpl)-like phenotypes and rescues ftz phenotypes. Mech. Dev. 2003, 120:1443-1453.
    • (2003) Mech. Dev. , vol.120 , pp. 1443-1453
    • Argiropoulos, B.1    Ho, J.2    Blachuta, B.J.3    Tayyab, I.4    Percival-Smith, A.5
  • 2
    • 0034660455 scopus 로고    scopus 로고
    • Phosphorylation status of the SCR homeodomain determines its functional activity: essential role for protein phophatase 2A, B'
    • Berry M., Gehring W. Phosphorylation status of the SCR homeodomain determines its functional activity: essential role for protein phophatase 2A, B'. EMBO J. 2000, 19:2946-2957.
    • (2000) EMBO J. , vol.19 , pp. 2946-2957
    • Berry, M.1    Gehring, W.2
  • 3
    • 0037020099 scopus 로고    scopus 로고
    • Mutations in the pho2 (bas2) transcription factor that differentially affect activation with its partner proteins bas1, pho4, and swi5
    • Bhoite L.T., Allen J.M., Garcia E., Thomas L.R., Gregory I.D., Voth W.P., Whelihan K., Rolfes R.J., Stillman D.J. Mutations in the pho2 (bas2) transcription factor that differentially affect activation with its partner proteins bas1, pho4, and swi5. J. Biol. Chem. 2002, 277:37612-37618.
    • (2002) J. Biol. Chem. , vol.277 , pp. 37612-37618
    • Bhoite, L.T.1    Allen, J.M.2    Garcia, E.3    Thomas, L.R.4    Gregory, I.D.5    Voth, W.P.6    Whelihan, K.7    Rolfes, R.J.8    Stillman, D.J.9
  • 4
    • 80051991355 scopus 로고    scopus 로고
    • Evolution of a derived protein-protein interaction between HoxA11 and Foxo1a in mammals caused by changes in intramolecular regulation
    • Brayer K.J., Lynch V.J., Wagner G.P. Evolution of a derived protein-protein interaction between HoxA11 and Foxo1a in mammals caused by changes in intramolecular regulation. PNAS 2011, 108:E414-E420.
    • (2011) PNAS , vol.108 , pp. E414-E420
    • Brayer, K.J.1    Lynch, V.J.2    Wagner, G.P.3
  • 5
    • 0022328481 scopus 로고
    • A eukaryotic transcriptional activator bearing the DNA specificity of a prokaryotic repressor
    • Brent R., Ptashne M. A eukaryotic transcriptional activator bearing the DNA specificity of a prokaryotic repressor. Cell 1985, 43:729-736.
    • (1985) Cell , vol.43 , pp. 729-736
    • Brent, R.1    Ptashne, M.2
  • 6
    • 0028173682 scopus 로고
    • Direct regulation of decapentaplegic by Ultrabithorax and its role in Drosophila midgut morphogenesis
    • Capovilla M., Brandt M., Botas J. Direct regulation of decapentaplegic by Ultrabithorax and its role in Drosophila midgut morphogenesis. Cell 1994, 76:461-475.
    • (1994) Cell , vol.76 , pp. 461-475
    • Capovilla, M.1    Brandt, M.2    Botas, J.3
  • 7
    • 0028991635 scopus 로고
    • Homeotic genes and the evolution of arthopods and chordates
    • Carroll S.B. Homeotic genes and the evolution of arthopods and chordates. Nature 1995, 376:479-485.
    • (1995) Nature , vol.376 , pp. 479-485
    • Carroll, S.B.1
  • 8
    • 22744439568 scopus 로고    scopus 로고
    • Evolution at two levels: on genes and form
    • Carroll S.B. Evolution at two levels: on genes and form. PLoS Biol. 2005, 3:1159-1167.
    • (2005) PLoS Biol. , vol.3 , pp. 1159-1167
    • Carroll, S.B.1
  • 10
    • 0034635969 scopus 로고    scopus 로고
    • Distinct Hox protein sequences determine specificity in different tissues
    • Chauvet S., Merabet S., Bilder D., Scott M.P., Pradel J., Graba Y. Distinct Hox protein sequences determine specificity in different tissues. PNAS 2000, 97:4064-4069.
    • (2000) PNAS , vol.97 , pp. 4064-4069
    • Chauvet, S.1    Merabet, S.2    Bilder, D.3    Scott, M.P.4    Pradel, J.5    Graba, Y.6
  • 14
    • 14644435825 scopus 로고    scopus 로고
    • Intrinsically unstructured proteins and their functions
    • Dyson H.J., Wright P.E. Intrinsically unstructured proteins and their functions. Nat. Rev. Mol. Cell Biol. 2005, 6:197-208.
    • (2005) Nat. Rev. Mol. Cell Biol. , vol.6 , pp. 197-208
    • Dyson, H.J.1    Wright, P.E.2
  • 15
    • 0027302167 scopus 로고
    • Functional specificity of the Antp Homeodomain
    • Furukubo-Tokunaga K., Flister S., Gehring W.J. Functional specificity of the Antp Homeodomain. PNAS 1993, 90:6360-6364.
    • (1993) PNAS , vol.90 , pp. 6360-6364
    • Furukubo-Tokunaga, K.1    Flister, S.2    Gehring, W.J.3
  • 16
    • 0037148774 scopus 로고    scopus 로고
    • Evolution of a transcriptional repression domain in an insect Hox protein
    • Galant R., Carroll S.B. Evolution of a transcriptional repression domain in an insect Hox protein. Nature 2002, 415:910-913.
    • (2002) Nature , vol.415 , pp. 910-913
    • Galant, R.1    Carroll, S.B.2
  • 17
    • 84892876722 scopus 로고    scopus 로고
    • Signatures of pleiotropy, economy and convergent evolution in a domain-resolved map of human-virus protein-protein interaction networks
    • Garamszegi S., Franzosa E.A., Xia Y. Signatures of pleiotropy, economy and convergent evolution in a domain-resolved map of human-virus protein-protein interaction networks. PLoS Pathog. 2013, 9:e1003778.
    • (2013) PLoS Pathog. , vol.9 , pp. e1003778
    • Garamszegi, S.1    Franzosa, E.A.2    Xia, Y.3
  • 18
    • 0025188768 scopus 로고
    • The specificities of Scr and Antp are defined by a distinct portion of each protein that includes the HD
    • Gibson G., Schier A., LeMotte P., Gehring W.J. The specificities of Scr and Antp are defined by a distinct portion of each protein that includes the HD. Cell 1990, 62:1087-1103.
    • (1990) Cell , vol.62 , pp. 1087-1103
    • Gibson, G.1    Schier, A.2    LeMotte, P.3    Gehring, W.J.4
  • 19
    • 0025165214 scopus 로고
    • Are cross-regulatory interactions between homoeotic genes func- tionally significant?
    • Gonzalez-Reyes A., Urquia N., Gehring W.J., Struhl G., Morata G. Are cross-regulatory interactions between homoeotic genes func- tionally significant?. Nature 1990, 344:78-80.
    • (1990) Nature , vol.344 , pp. 78-80
    • Gonzalez-Reyes, A.1    Urquia, N.2    Gehring, W.J.3    Struhl, G.4    Morata, G.5
  • 20
    • 0023254634 scopus 로고
    • Oestradiol induction of a glucocorticoid-responsive gene by a chimaeric receptor
    • Green S., Chambon P. Oestradiol induction of a glucocorticoid-responsive gene by a chimaeric receptor. Nature 1987, 325:75-78.
    • (1987) Nature , vol.325 , pp. 75-78
    • Green, S.1    Chambon, P.2
  • 21
    • 68749107059 scopus 로고    scopus 로고
    • Protein sectors: evolutionary units of three-dimensional structure
    • Halabi N., Rivoire O., Leibler S., Ranganathan R. Protein sectors: evolutionary units of three-dimensional structure. Cell 2009, 138:774-786.
    • (2009) Cell , vol.138 , pp. 774-786
    • Halabi, N.1    Rivoire, O.2    Leibler, S.3    Ranganathan, R.4
  • 22
    • 84873468307 scopus 로고    scopus 로고
    • Variation and constraint in Hox gene evolution
    • Heffer A., Xiang J., Pick L. Variation and constraint in Hox gene evolution. PNAS 2013, 110:2211-2216.
    • (2013) PNAS , vol.110 , pp. 2211-2216
    • Heffer, A.1    Xiang, J.2    Pick, L.3
  • 23
    • 81355127456 scopus 로고    scopus 로고
    • Ftz evolution: findings, hypotheses and speculations
    • Heffer A., Löhr U., Pick L. Ftz evolution: findings, hypotheses and speculations. Bioessays 2011, 33:910-918.
    • (2011) Bioessays , vol.33 , pp. 910-918
    • Heffer, A.1    Löhr, U.2    Pick, L.3
  • 24
    • 34347235156 scopus 로고    scopus 로고
    • Intrinsic disorder as a mechanism to optimize allosteric coupling in proteins
    • Hilser V.J., Thompson E.B. Intrinsic disorder as a mechanism to optimize allosteric coupling in proteins. PNAS 2007, 104:8311-8315.
    • (2007) PNAS , vol.104 , pp. 8311-8315
    • Hilser, V.J.1    Thompson, E.B.2
  • 25
    • 29644443255 scopus 로고    scopus 로고
    • Pleiotropic functions of a conserved insect-specific Hox peptide motif
    • Hittinger C.T., Stern D.L., Carroll S.B. Pleiotropic functions of a conserved insect-specific Hox peptide motif. Development 2005, 132:5261-5270.
    • (2005) Development , vol.132 , pp. 5261-5270
    • Hittinger, C.T.1    Stern, D.L.2    Carroll, S.B.3
  • 26
    • 70349546862 scopus 로고    scopus 로고
    • Global analysis of Cdk1 substrate phosphorylation sites provides insights into evolution
    • Holt L.J., Tuch B.B., Villén J., Johnson A.D., Gygi S.P., Morgan D.O. Global analysis of Cdk1 substrate phosphorylation sites provides insights into evolution. Science 2009, 325:1682-1686.
    • (2009) Science , vol.325 , pp. 1682-1686
    • Holt, L.J.1    Tuch, B.B.2    Villén, J.3    Johnson, A.D.4    Gygi, S.P.5    Morgan, D.O.6
  • 28
    • 0030052528 scopus 로고    scopus 로고
    • Genetic characterization of the Homeodomain-independent activity of the Drosophila fushi tarazu gene product
    • Hyduk D., Percival-Smith A. Genetic characterization of the Homeodomain-independent activity of the Drosophila fushi tarazu gene product. Genetics 1996, 142:481-492.
    • (1996) Genetics , vol.142 , pp. 481-492
    • Hyduk, D.1    Percival-Smith, A.2
  • 29
    • 77954854598 scopus 로고    scopus 로고
    • Dissecting the functional specificities of two Hox proteins
    • Joshi R., Sun L., Mann R.S. Dissecting the functional specificities of two Hox proteins. Genes Dev. 2010, 24:1533-1545.
    • (2010) Genes Dev. , vol.24 , pp. 1533-1545
    • Joshi, R.1    Sun, L.2    Mann, R.S.3
  • 30
    • 35548931586 scopus 로고    scopus 로고
    • Functional specificity of a Hox protein mediated by the recognition of minor groove structure
    • Joshi R., Passner J.M., Rohs R., Jain R., Sosinsky A., et al. Functional specificity of a Hox protein mediated by the recognition of minor groove structure. Cell 2007, 131:530-543.
    • (2007) Cell , vol.131 , pp. 530-543
    • Joshi, R.1    Passner, J.M.2    Rohs, R.3    Jain, R.4    Sosinsky, A.5
  • 31
    • 33745965237 scopus 로고    scopus 로고
    • The specification of a highly derived arthropod appendage, the Dro- sophila labial palps, requires the joint action of selectors and sig- naling pathways
    • Joulia L., Deutsch J., Bourbon H., Cribbs D.L. The specification of a highly derived arthropod appendage, the Dro- sophila labial palps, requires the joint action of selectors and sig- naling pathways. Dev. Genes Evol. 2006, 216:431-442.
    • (2006) Dev. Genes Evol. , vol.216 , pp. 431-442
    • Joulia, L.1    Deutsch, J.2    Bourbon, H.3    Cribbs, D.L.4
  • 32
    • 0022622235 scopus 로고
    • Separation of DNA binding from the transcription-activating function of a eukaryotic regulatory protein
    • Keegan L., Gill G., Ptashne M. Separation of DNA binding from the transcription-activating function of a eukaryotic regulatory protein. Science 1986, 231:699-704.
    • (1986) Science , vol.231 , pp. 699-704
    • Keegan, L.1    Gill, G.2    Ptashne, M.3
  • 33
    • 0016669094 scopus 로고
    • Evolution at two levels in humans and chimpanzees
    • King M.C., Wilson A.C. Evolution at two levels in humans and chimpanzees. Science 1975, 188:107-116.
    • (1975) Science , vol.188 , pp. 107-116
    • King, M.C.1    Wilson, A.C.2
  • 35
    • 0021139598 scopus 로고
    • Sequence of a Drosophila segmentation gene: protein structure homology with DNA- binding proteins
    • Laughton A., Scott M.P. Sequence of a Drosophila segmentation gene: protein structure homology with DNA- binding proteins. Nature 1984, 310:25-30.
    • (1984) Nature , vol.310 , pp. 25-30
    • Laughton, A.1    Scott, M.P.2
  • 36
    • 84855496550 scopus 로고    scopus 로고
    • Variable motif utilization in homeotic selector (Hox)-cofactor complex formation controls specificity
    • Lelli K.M., Noro B., Mann R.S. Variable motif utilization in homeotic selector (Hox)-cofactor complex formation controls specificity. PNAS 2011, 108:21122-21127.
    • (2011) PNAS , vol.108 , pp. 21122-21127
    • Lelli, K.M.1    Noro, B.2    Mann, R.S.3
  • 37
    • 0018240421 scopus 로고
    • A gene complex controlling segmentation in Drosophila
    • Lewis E.B. A gene complex controlling segmentation in Drosophila. Nature 1978, 276:565-570.
    • (1978) Nature , vol.276 , pp. 565-570
    • Lewis, E.B.1
  • 38
    • 0019209665 scopus 로고
    • Genetic anlysis of the Antennapedia gene complex (Ant-C) and adjacent chromosomal regions of Drosophila melanogaster. II. Polytene Chromosome segments 84A-84B1, 2.
    • Lewis R.A., Wakimoto B.T., Denell R.E., Kaufman T.C. Genetic anlysis of the Antennapedia gene complex (Ant-C) and adjacent chromosomal regions of Drosophila melanogaster. II. Polytene Chromosome segments 84A-84B1, 2. Genetics 1980, 95:383-397.
    • (1980) Genetics , vol.95 , pp. 383-397
    • Lewis, R.A.1    Wakimoto, B.T.2    Denell, R.E.3    Kaufman, T.C.4
  • 39
    • 0026718999 scopus 로고
    • Mapping functional specificity in the Dfd and Ubx homeo domains
    • Lin L., McGinnis W.J. Mapping functional specificity in the Dfd and Ubx homeo domains. Genes Dev. 1992, 6:1071-1081.
    • (1992) Genes Dev. , vol.6 , pp. 1071-1081
    • Lin, L.1    McGinnis, W.J.2
  • 40
    • 51049119258 scopus 로고    scopus 로고
    • Multiple intrinsically disordered sequences alter DNA binding by the homeodomain of the Drosophila HOX protein Ultrabithorax
    • Liu Y., Matthews K.S., Bondos S.E. Multiple intrinsically disordered sequences alter DNA binding by the homeodomain of the Drosophila HOX protein Ultrabithorax. J Biol. Chem. 2008, 283:20874-20887.
    • (2008) J Biol. Chem. , vol.283 , pp. 20874-20887
    • Liu, Y.1    Matthews, K.S.2    Bondos, S.E.3
  • 41
    • 17144415299 scopus 로고    scopus 로고
    • Cofactor-interaction motifs and the cooption of a homeotic Hox protein into the segmentation pathway of Drosophila melanogaster
    • Lohr U., Pick L. Cofactor-interaction motifs and the cooption of a homeotic Hox protein into the segmentation pathway of Drosophila melanogaster. Curr. Biol. 2005, 15:643-649.
    • (2005) Curr. Biol. , vol.15 , pp. 643-649
    • Lohr, U.1    Pick, L.2
  • 42
    • 83555162573 scopus 로고    scopus 로고
    • Regulatory evolution via adaptive divergence of a phosphoswitch in the transcription factor CEBPB
    • Lynch V.J., Mae G., Wagner G.P. Regulatory evolution via adaptive divergence of a phosphoswitch in the transcription factor CEBPB. Nature 2011, 480:383-386.
    • (2011) Nature , vol.480 , pp. 383-386
    • Lynch, V.J.1    Mae, G.2    Wagner, G.P.3
  • 43
    • 51549097146 scopus 로고    scopus 로고
    • Resurrecting the role of transcription factor change in developmental evolution
    • Lynch V.J., Wagner G.P. Resurrecting the role of transcription factor change in developmental evolution. Evolution 2008, 62:2131-2154.
    • (2008) Evolution , vol.62 , pp. 2131-2154
    • Lynch, V.J.1    Wagner, G.P.2
  • 44
    • 65249167505 scopus 로고    scopus 로고
    • DNA binding site sequence directs glucocorticoid receptor structure and activity
    • Meijsing S.H., Pufall M.A., So A.Y., Bates D.L., Chen L., Yamamoto K.R. DNA binding site sequence directs glucocorticoid receptor structure and activity. Science 2009, 324:407-410.
    • (2009) Science , vol.324 , pp. 407-410
    • Meijsing, S.H.1    Pufall, M.A.2    So, A.Y.3    Bates, D.L.4    Chen, L.5    Yamamoto, K.R.6
  • 45
    • 84890858140 scopus 로고    scopus 로고
    • Tracking context-specific transcription factors regulating hox activity
    • Merabet S., Dard A. Tracking context-specific transcription factors regulating hox activity. Dev. Dyn. 2013, 243:16-23.
    • (2013) Dev. Dyn. , vol.243 , pp. 16-23
    • Merabet, S.1    Dard, A.2
  • 46
    • 79959219860 scopus 로고    scopus 로고
    • On the border of the homeotic function: re-evaluating the controversial role of cofactor-recruiting motifs: the role of cofactor-recruiting motifs in conferring Hox evolutionary flexibility may critically depend on the protein environment
    • Merabet S., Hudry B. On the border of the homeotic function: re-evaluating the controversial role of cofactor-recruiting motifs: the role of cofactor-recruiting motifs in conferring Hox evolutionary flexibility may critically depend on the protein environment. Bioessays 2011, 33:499-507.
    • (2011) Bioessays , vol.33 , pp. 499-507
    • Merabet, S.1    Hudry, B.2
  • 48
    • 0026504525 scopus 로고
    • Homeobox genes and axial patterning
    • McGinnis W., Krumlauf R. Homeobox genes and axial patterning. Cell 1992, 68:283-302.
    • (1992) Cell , vol.68 , pp. 283-302
    • McGinnis, W.1    Krumlauf, R.2
  • 50
    • 33748953868 scopus 로고    scopus 로고
    • Peptides mediating interaction networks: new leads at last
    • Neduva V., Russell R.B. Peptides mediating interaction networks: new leads at last. Curr. Opin. Biotechnol. 2006, 17:465-471.
    • (2006) Curr. Opin. Biotechnol. , vol.17 , pp. 465-471
    • Neduva, V.1    Russell, R.B.2
  • 51
    • 29144455315 scopus 로고    scopus 로고
    • Systematic discovery of new recognition peptides mediating protein interaction networks
    • Neduva V., Linding R., Su-Angrand I., Stark A., et al. Systematic discovery of new recognition peptides mediating protein interaction networks. PLoS Biol. 2005, 3:e405.
    • (2005) PLoS Biol. , vol.3 , pp. e405
    • Neduva, V.1    Linding, R.2    Su-Angrand, I.3    Stark, A.4
  • 54
    • 0026572990 scopus 로고
    • Organogenesis in Drosophila melanogaster: embryonic salivary gland determination is controlled by homeotic and dorsoventral patterning genes
    • Panzer S., Weigel D., Beckendorf S.K. Organogenesis in Drosophila melanogaster: embryonic salivary gland determination is controlled by homeotic and dorsoventral patterning genes. Development 1992, 114:49-57.
    • (1992) Development , vol.114 , pp. 49-57
    • Panzer, S.1    Weigel, D.2    Beckendorf, S.K.3
  • 55
    • 84888596465 scopus 로고    scopus 로고
    • Developmental competence and the induction of ectopic proboscises in Drosophila melanogaster
    • Percival-Smith A., Sivanantharajah L., Pelling J.J., Teft W.A. Developmental competence and the induction of ectopic proboscises in Drosophila melanogaster. Dev. Genes Evol. 2013, 223:375-387.
    • (2013) Dev. Genes Evol. , vol.223 , pp. 375-387
    • Percival-Smith, A.1    Sivanantharajah, L.2    Pelling, J.J.3    Teft, W.A.4
  • 56
    • 0031696839 scopus 로고    scopus 로고
    • Analysis in Drosophila melanogaster of the interaction between Sex combs reduced and extradenticle activity in the determination of tarsus and arista identity
    • Percival-Smith A., Hayden D.J. Analysis in Drosophila melanogaster of the interaction between Sex combs reduced and extradenticle activity in the determination of tarsus and arista identity. Genetics 1998, 150:189-198.
    • (1998) Genetics , vol.150 , pp. 189-198
    • Percival-Smith, A.1    Hayden, D.J.2
  • 57
    • 0031440222 scopus 로고    scopus 로고
    • Genetic characterization of the role of the two HOX proteins, Proboscipedia and Sex combs reduced, in determination of adult antennal, tarsal, maxillary palp and proboscis identities in Drosophila melanogaster
    • Percival-Smith A., Weber J., Gilfoyle E., Wilson P. Genetic characterization of the role of the two HOX proteins, Proboscipedia and Sex combs reduced, in determination of adult antennal, tarsal, maxillary palp and proboscis identities in Drosophila melanogaster. Development 1997, 124:5049-5062.
    • (1997) Development , vol.124 , pp. 5049-5062
    • Percival-Smith, A.1    Weber, J.2    Gilfoyle, E.3    Wilson, P.4
  • 58
    • 0030601974 scopus 로고    scopus 로고
    • The nonreceptor protein tyrosine phosphatase corkscrew functions in multiple receptor tyrosine kinase pathways in Drosophila
    • Perkins L.A., Johnson M.R., Melnick M.B., Perrimon N. The nonreceptor protein tyrosine phosphatase corkscrew functions in multiple receptor tyrosine kinase pathways in Drosophila. Dev. Biol. 1996, 180:63-81.
    • (1996) Dev. Biol. , vol.180 , pp. 63-81
    • Perkins, L.A.1    Johnson, M.R.2    Melnick, M.B.3    Perrimon, N.4
  • 59
    • 84860997881 scopus 로고    scopus 로고
    • Hox gene evolution: multiple mechanisms contributing to evolutionary novelties
    • Pick L., Heffer A. Hox gene evolution: multiple mechanisms contributing to evolutionary novelties. Ann. N Y Acad. Sci. 2012, 1256:15-32.
    • (2012) Ann. N Y Acad. Sci. , vol.1256 , pp. 15-32
    • Pick, L.1    Heffer, A.2
  • 60
    • 46049101802 scopus 로고    scopus 로고
    • The YPWM motif link Antennapedia to the basal transcriptional machinery
    • Prince F., Katsuyama T., Oshima Y., Plaza S., Resendez-Perez D., et al. The YPWM motif link Antennapedia to the basal transcriptional machinery. Development 2008, 135:1669-1679.
    • (2008) Development , vol.135 , pp. 1669-1679
    • Prince, F.1    Katsuyama, T.2    Oshima, Y.3    Plaza, S.4    Resendez-Perez, D.5
  • 61
    • 0023683667 scopus 로고
    • How eukaryotic transcriptional activators work
    • Ptashne M. How eukaryotic transcriptional activators work. Nature 1988, 335:683-689.
    • (1988) Nature , vol.335 , pp. 683-689
    • Ptashne, M.1
  • 62
    • 0035395887 scopus 로고    scopus 로고
    • The eyeless homeodomain is dispensable for eye development in Drosophila
    • Punzo C., Kurata S., Gehring W.J. The eyeless homeodomain is dispensable for eye development in Drosophila. Genes Dev. 2001, 15:1716-1723.
    • (2001) Genes Dev. , vol.15 , pp. 1716-1723
    • Punzo, C.1    Kurata, S.2    Gehring, W.J.3
  • 63
    • 0037148839 scopus 로고    scopus 로고
    • Hox protein mutation and macroevolution of the insect body plan
    • Ronshaugen M., Mcginnis N., Mcginnis W. Hox protein mutation and macroevolution of the insect body plan. Nature 2002, 415:914-917.
    • (2002) Nature , vol.415 , pp. 914-917
    • Ronshaugen, M.1    Mcginnis, N.2    Mcginnis, W.3
  • 64
    • 0008231153 scopus 로고    scopus 로고
    • The control of trunk Hox specificity and activity by Extradenticle
    • Ryoo H.D., Mann R.S. The control of trunk Hox specificity and activity by Extradenticle. Genes Dev. 1999, 13:1704-1716.
    • (1999) Genes Dev. , vol.13 , pp. 1704-1716
    • Ryoo, H.D.1    Mann, R.S.2
  • 65
    • 84901338905 scopus 로고    scopus 로고
    • Acquisition of a leucine zipper motif as a mechanism of antimorphy for an allele of the Drosophila Hox gene Sex combs reduced
    • Sivanantharajah L., Percival-Smith A. Acquisition of a leucine zipper motif as a mechanism of antimorphy for an allele of the Drosophila Hox gene Sex combs reduced. G3: Genes, Genomes, Genet. 2014, 4:829-838.
    • (2014) G3: Genes, Genomes, Genet. , vol.4 , pp. 829-838
    • Sivanantharajah, L.1    Percival-Smith, A.2
  • 66
    • 67849090500 scopus 로고    scopus 로고
    • Analysis of the sequence and phenotype of Drosophila Sex combs reduced alleles reveals potential functions of conserved protein motifs of the Sex combs reduced protein
    • Sivanantharajah L., Percival-Smith A. Analysis of the sequence and phenotype of Drosophila Sex combs reduced alleles reveals potential functions of conserved protein motifs of the Sex combs reduced protein. Genetics 2009, 182:191-203.
    • (2009) Genetics , vol.182 , pp. 191-203
    • Sivanantharajah, L.1    Percival-Smith, A.2
  • 67
    • 0034251814 scopus 로고    scopus 로고
    • Evolutionary developmental biology and the problem of variation
    • Stern D.L. Evolutionary developmental biology and the problem of variation. Evolution 2000, 54:1079-1091.
    • (2000) Evolution , vol.54 , pp. 1079-1091
    • Stern, D.L.1
  • 68
    • 0004002161 scopus 로고
    • Genes controlling segmental specification in the Drosophila thorax
    • Struhl G. Genes controlling segmental specification in the Drosophila thorax. PNAS 1982, 79:7380-7384.
    • (1982) PNAS , vol.79 , pp. 7380-7384
    • Struhl, G.1
  • 69
    • 23244444605 scopus 로고    scopus 로고
    • Saccharomyces cerevisiae Rad9 acts as a Mec1 adaptor to allow Rad53 activation
    • Sweeney F.D., Yang F., Chi A., Shabanowitz J., Hunt D.F., Durocher D. Saccharomyces cerevisiae Rad9 acts as a Mec1 adaptor to allow Rad53 activation. Curr. Biol. 2005, 15:1364-1375.
    • (2005) Curr. Biol. , vol.15 , pp. 1364-1375
    • Sweeney, F.D.1    Yang, F.2    Chi, A.3    Shabanowitz, J.4    Hunt, D.F.5    Durocher, D.6
  • 70
    • 4143068299 scopus 로고    scopus 로고
    • Analysis of Drosophila proboscipedia mutant alleles
    • Tayyab I., Hallahan H., Percival-Smith A. Analysis of Drosophila proboscipedia mutant alleles. Genome 2004, 47:600-609.
    • (2004) Genome , vol.47 , pp. 600-609
    • Tayyab, I.1    Hallahan, H.2    Percival-Smith, A.3
  • 71
    • 29644440598 scopus 로고    scopus 로고
    • Evolutionary conserved domains required for activation and repression functions of the Drosophila Hox protein Ultrabithorax
    • Tour E., Hittinger C.T., McGinnis W. Evolutionary conserved domains required for activation and repression functions of the Drosophila Hox protein Ultrabithorax. Development 2005, 132:5271-5281.
    • (2005) Development , vol.132 , pp. 5271-5281
    • Tour, E.1    Hittinger, C.T.2    McGinnis, W.3
  • 72
    • 84902446852 scopus 로고    scopus 로고
    • Short linear motifs: ubiquitous and functionally diverse protein interaction modules directing cell regulation
    • Van Roey K., Uyar B., Weatheritt R.J., Dinkel H., Seiler M., Budd A., Gibson T.J., Davey N.E. Short linear motifs: ubiquitous and functionally diverse protein interaction modules directing cell regulation. Chem. Rev. 2014, 114:6733-6778.
    • (2014) Chem. Rev. , vol.114 , pp. 6733-6778
    • Van Roey, K.1    Uyar, B.2    Weatheritt, R.J.3    Dinkel, H.4    Seiler, M.5    Budd, A.6    Gibson, T.J.7    Davey, N.E.8
  • 73
    • 79951799418 scopus 로고    scopus 로고
    • The pleiotropic structure of the genotype-phenotype map: the evolvability of complex organisms
    • Wagner G.P., Zhang J. The pleiotropic structure of the genotype-phenotype map: the evolvability of complex organisms. Nature Rev. Genet. 2011, 12:204-213.
    • (2011) Nature Rev. Genet. , vol.12 , pp. 204-213
    • Wagner, G.P.1    Zhang, J.2
  • 74
    • 45349091096 scopus 로고    scopus 로고
    • The gene regulatory logic of transcription factor evolution
    • Wagner G.P., Lynch V.J. The gene regulatory logic of transcription factor evolution. Trends Ecol. Evol. 2008, 23:377-385.
    • (2008) Trends Ecol. Evol. , vol.23 , pp. 377-385
    • Wagner, G.P.1    Lynch, V.J.2
  • 75
    • 1542358787 scopus 로고    scopus 로고
    • Prediction and functional analysis of native disorder in proteins from the three kingdoms of life
    • Ward J.J., Sodhi J.S., McGuffin L.J., Buxton B.F., Jones D.T. Prediction and functional analysis of native disorder in proteins from the three kingdoms of life. J. Mol. Biol. 2004, 337:635-645.
    • (2004) J. Mol. Biol. , vol.337 , pp. 635-645
    • Ward, J.J.1    Sodhi, J.S.2    McGuffin, L.J.3    Buxton, B.F.4    Jones, D.T.5
  • 76
    • 0032749078 scopus 로고    scopus 로고
    • Intrinsically unstructured proteins: re-assessing the protein structure-function paradigm
    • Wright P.E., Dyson H.J. Intrinsically unstructured proteins: re-assessing the protein structure-function paradigm. J. Mol. Biol. 1999, 293:321-331.
    • (1999) J. Mol. Biol. , vol.293 , pp. 321-331
    • Wright, P.E.1    Dyson, H.J.2
  • 78
    • 0027223344 scopus 로고
    • The mouse Hox-1.3 gene is functionally equivalent to the Drosophila Sex combs reduced gene
    • Zhao J.J., Lazzarini R.A., Pick L. The mouse Hox-1.3 gene is functionally equivalent to the Drosophila Sex combs reduced gene. Gen. Dev. 1993, 7:343-354.
    • (1993) Gen. Dev. , vol.7 , pp. 343-354
    • Zhao, J.J.1    Lazzarini, R.A.2    Pick, L.3
  • 79
    • 0029917042 scopus 로고    scopus 로고
    • Functional dissection of the mouse Hox-a5 gene
    • Zhao J.J., Lazzarini R.A., Pick L. Functional dissection of the mouse Hox-a5 gene. EMBO J. 1996, 15:1313-1322.
    • (1996) EMBO J. , vol.15 , pp. 1313-1322
    • Zhao, J.J.1    Lazzarini, R.A.2    Pick, L.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.