Genetic characterization of the role of the two HOX proteins, Proboscipedia and Sex Combs Reduced, in determination of adult antennal, tarsal, maxillary palp and proboscis identities in Drosophila melanogaster

Development

Volumn 124, Issue 24, 1997, Pages 5049-5062

  Percival Smith, Anthony ^a   Weber, Jennifer ^a   Gilfoyle, Elaine ^a   Wilson, Peggy ^a  

^a UNIVERSITY OF WESTERN ONTARIO   (Canada)

Author keywords

Drosophila; HOX function; Induction; Limb development; Pattern formation; Proboscipedia; Sex combs reduced

Indexed keywords

HOMEODOMAIN PROTEIN;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; COMPLEX FORMATION; CONTROLLED STUDY; DEVELOPMENTAL GENETICS; DROSOPHILA MELANOGASTER; EMBRYO; EMBRYO DEVELOPMENT; EMBRYO PATTERN FORMATION; NONHUMAN; ORGANOGENESIS; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION;

ANIMALS; BODY PATTERNING; DNA, RECOMBINANT; DROSOPHILA MELANOGASTER; DROSOPHILA PROTEINS; EXTREMITIES; GENE EXPRESSION REGULATION, DEVELOPMENTAL; HEAD; HOMEODOMAIN PROTEINS; INSECT PROTEINS; LARVA; MOSAICISM; PHENOTYPE; TEMPERATURE; THORAX; TRANSCRIPTION FACTORS;

EID: 0031440222     PISSN: 09501991     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (68)

1. Andrews, D. J. and Scott, M. P. (1992). Downstream of the homeotic genes. The New Biologist 4, 5-15.
2. Aspland, S. E. and White, R. A. H. (1997). Nucleocytoplasmic localisation of extradenticle protein is spatially regulated throughout development in Drosophila. Development 124, 741-747.
3. Basler, K. and Struhl, G. (1994). Compartment boundaries and the control of Drosophila limb pattern by hedgehog protein. Nature 368, 208-214.
4. Capovilla, M., Brandt, M. and Botas, J. (1994). Direct regulation of decapentaplegic by Ultrabithorax and its role in Drosophila midgut morphogenesis Cell 76, 461-475.
5. Carroll, S. B. (1995). Homeotic genes and the evolution of arthopods and chordates. Nature 376, 479-485.
6. Castelli-Gair, J. and Akam, M. (1995). How the Hox gene Utrabithorax specifies two different segments: the significance of spatial and temporal regulation within metameres. Development 121, 2973-2982.
7. Chadwick, R. and McGinnis, W. (1987). Temporal and spacial distribution of transcripts from the Deformed gene of Drosophila. EMBO J. 6, 779-789.
8. Chan, S-K. and Mann R. S. (1993). The segment identity functions of Ultrabithorax are contained within its homeodomain and carboxy-terminal sequences. Genes and Dev. 7, 796-811.
9. Chan, S-K., Jaffe, L., Capovilla, M., Botas, J. and Mann, R. S. (1994). The DNA binding specificity of Ultrabithorax is modulated by cooperative interactions with Extradenticle, another Homeoprotein. Cell 78, 803-813.
10. Chan, S-K., Pöpperl, H., Krumlauf, R. and Mann R. S. (1996). An extradenticle-induced conformational change in a HOX protein overcomes an inhibitory function of the conserved hexapeptide motif. EMBO J. 15, 2476-2487.
11. Cribbs, D. L., Pultz, M. A., Johnson, D., Mazzulla, M. and Kaufman, T. C. (1992). Structural complexity and evolutionary conservation of the Drosophila homeotic gene proboscipedia. EMBO J. 11, 1437-1449.
12. Cribbs, D. L., Benassayag, C., Randazzo, F. M. and Kaufman, T. C. (1995). Levels of homeotic protein function can determine developmental identity: evidence from low-level expression of the Drosophila homeotic gene proboscipedia under Hsp70 control. EMBO J. 14, 767-778.
13. Currie, D. and Bate, M. (1991). Development of adult abdominal muscles in Drosophila: Adult myoblasts express twist and are associated with nerves. Development 113, 91-102.
14. Dranginis, A. M. (1990). Binding of yeast a1 and α2 as a heterodimer to the operator DNA of a haploid-specific gene. Nature 347, 682-685.
15. Furukubo-Tokunaga, K. Flister, S. and Gehring, W. J. (1993). Functional specificity of the Antennapedia homeodomain. Proc. Natl. Acad. Sci. USA 90, 6360-6464.
16. Gehring, W. J., Qian, Y. Q., Billeter, M., Furukubo-Tokunaga, K., Schier, A. F., Resendez-Perez, D., Affolter, M. and Wüthrich, K. (1994). Homeodomain-DNA recognition. Cell 78, 211-223.
17. Gibson, G., Schier, A. F., LeMotte, P. and Gehring, W. J. (1990). The specificities of Sex combs reduced and Antennapedia are defined by a distinct portion of each protein that includes the homeodomain. Cell 62, 1087-1103.
18. Glickman, M. A. and Brower, D. L. (1988). Expression of Sex combs reduced protein in Drosophila larvae. Dev. Biol. 127, 113-118.
19. Golic, K. G. (1991). Site-specific recombination between homologous chromosomes in Drosophila. Science 252, 958-961.
20. Gonzalez-Crespo, S. and Morata, G. (1996). Genetic evidence for the subdivision of the arthropod limb into coxopodite and telopodite. Development 122, 3921-3928.
21. Goutte, C. and Johnson, A. D. (1988). al protein alters the DNA binding specificity of α2 repressor. Cell 52, 875-882.
22. Hall, M. N. and Johnson, A. D. (1987). Homeodomain of the yeast repressor α2 is a sequence-specific DNA-binding domain but is not sufficient for repression. Science 237, 1007-1012.
23. Hanes, S. D. and Brent, R. (1991). A genetic model for interaction of the Homeodomain recognition helix with DNA. Science 251, 426-430.
24. Herskowitz, I. (1987) Functional inactivation of genes by dominant negative mutations Nature 329, 219-222.
25. Herskowitz, I. (1989). A regulatory hierarchy for cell specialization in yeast. Nature 342, 749-757.
26. Hill, R. J. and Sternberg, P. W. (1992). The gene lin-3 encodes an inductive signal for vulval development in C. elegans. Nature 358, 470-476.
27. Hunt, P. and Krumlauf, R. (1991). Deciphering the Hox code: Clues to patterning brachial regions of the head. Cell 66, 1075-1078.
28. Immergluck, K., Lawrence, P. A. and Bienz, M. (1990). Induction across germ layers in Drosophila mediated by a genetic cascade. Cell 62, 261-268.
29. Johnson, F. B., Parker, E. and Krasnow, M. A. (1995). Extradenticle protein is a selective cofactor for the Drosophila homeotics: Role of the homeodomain and YPWM amino acid motif in the interaction. Proc. Natl. Acad. Sci. USA 92, 739-743.
30. Kaufman, T. C. (1978). Cytogenetic analysis of chromosome 3 in Drosophila melanoguster: isolation and characterization of four new alleles of proboscipedia (pb) locus. Genetics 90, 579-596.
31. Kaufman, T. C., Seeger, M. A. and Olsen, G. (1990). Molecular and genetic organization to the Antennapedia gene complex of Drosophila melanogaster. In Advances in Genetics: Genetic Regulatory Hierarchies in Development. P. R. F. Wright, ed., Vol. 27. pp. 309-362.
32. Klemenz, R., Weber, U. and Gehring, W. J. (1987). The white gene as a marker in a new P-elemnt vector for gene transfer in Drosophila. NAR 10, 3947-3959.
33. Kuroiwa, A., Kloter, U., Baumgartner, P. and Gehring, W. J. (1985). Cloning of the homeotic Sex combs reduced gene in Drosophila and in situ localization of its transcripts. EMBO J. 4, 3757-3764.
34. LeMotte, P. K., Kuroiwa, A., Fessier, L. I. and Gehring, W. J. (1989). The homeotic gene Sex combs reduced of Drosophila: gene structure and embryonic expression. EMBO J. 8, 219-227.
35. Lewis, E. B. (1978). A gene complex controlling segmentation in Drosophila. Nature 276, 565-570.
36. Li, T., Stark, M. R., Johnson, A. D. and Wolberger, C. (1995). Crystal structure of the MATal/MATα2 homeodomain helerodimer bound to DNA. Science 270, 262-269.
37. Lindsley, D. and Zimm, G. (1992). The Genome of Drosophila melanogaster. Academic Press. San Diego, CA.
38. Mahaffey, J. and Kaufman, T. C. (1987). Distribution of the Sex combs reduced gene products in Drosophila melanogaster. Genetics 117, 51-60.
39. Mann, R. S. and Hogness, D. S. (1990). Functional dissection of Ultrabithorax proteins in D. melanogaster. Cell 60, 597-610.
40. McGinnis, W. and Krumlauf, R. (1992). Homeobox genes and axial patterning. Cell 68, 283-302.
41. Padgett, R. W., St Johnston, D. and Gelbart, W. M. (1987). A transcript from a Drosophila pattern gene predicts a protein homologous to the transforming growth factor-beta family. Nature 325, 81-84.
42. Panzer, S., Weigel, D. and Beckendorf, S. K. (1992). Organogenesis in Drosophila melanogaster: embryonic salivary gland determination is controlled by homeotic and dorsoventral patterning genes. Development 114, 49-57.
43. Pattatucci, A. and Kaufman, T. C. (1991). The homeotic gene Sex combs reduced of Drosophila melanogaster is differentially regulated in the embryonic and imaginal stages of development. Genetics 129, 443-461.
44. Pattatucci, A. M., Otteson, D. C. and Kaufman, T. C. (1991). A functional and structural analysis of the Sex combs reduced locus ot Drosophila melanogaster. Genetics 129, 423-441.
45. Pederson, J. D., Kiehart, D. P. and Mahaffey, J. W. (1996). The role of HOMC genes in segmental transformations: Reexamination of the Drosophila Sex combs reduced embryonic phenotype. Dev. Biol. 180, 131-142.
46. Peifer, M., Karen, F. and Bender, W. (1987). The bithorax complex: control of segmental identity. Genes and Dev. 1, 891-898.
47. Peifer, M. and Wieschaus, E. (1990). Mutations in the Drosophila gene extradenticle affect the way specific homeodomain proteins regulate segmental identity. Genes and Dev. 4, 1209-1223.
48. Percival-Smith, A., Muller, M., Affolter, M. and Gehring, W. J. (1990). The interaction with DNA of wild-type and mutant fushi tarazu homeodomains. EMBO J. 9, 3967-3974.
49. Pultz, M. A., Diedcrich, R. J., Cribbs, D. L. and Kaufman, T. C. (1988). The proboscipedia locus of the Antennapedia Complex: a molecular and genetic analysis. Genes and Dev 2, 901-920.
50. Randazzo, F. M., Cribbs, D. L. and Kaufman, T. C. (1991). Rescue and regulation of proboscipedia: a homeotic gene of the Antennapedia complex. Development 113, 257-271.
51. Rauskolb, C., Peifer, M. and Wieschaus, K. (1993). extradenticle, a regulator of homeotic gene activity, is a homolog of the homeobox-containing. Human proto-oncogene pbx 1. Cell 74, 1101-1112.
52. Reuter, R. and Scott, M. P. (1990). Expression and function of the homeotic genes Antennapedia and Sex combs reduced in embryonic midgut of Drosophila. Development 109, 289-303.
53. Rubin, G. M. and Spradling, A. C. (1982). Genetic transformation of Drosophila with transposable element vectors. Science 218, 348-353.
54. Salser, S. J. and Kenyon, C. (1996). A C. elegans Hox gene switches on, off, on. and off again to regulate proliferation, differentiation, and morphogenesis. Development 122, 1651-1161.
55. Schier, A. F. and Gehring. W. J. (1992). Direct homeodomain-DNA interaction in the autoregulation of the fushi tarazu gene. Nature 356, 804-807.
56. Schneuwly, S., Klemenz, R. and Gehring, W. J. (1987). Redesigning the body plan of Drosophila by ectopic expression of the homeotic gene Antennapedia. Nature 235, 816-818.
57. Slack, J. M. W., Holland, P. W. H. and Graham, C. F. (1993). The Zootype and the Phylotypic Stage. Nature 361, 490-492.
58. Struhl, G. (1981a). A homeotic mutation transforming leg to antenna in Drosophila. Nature 292, 635-638.
59. Struhl, G. (1981b). Anterior and posterior compartments in the proboscis of Drosphila. Dev. Biol. 84, 372-385.
60. Struhl, G. (1982). Genes controlling segmental specification in the Drosophila thorax. Proc. Natl. Acad. Sci. USA 79, 7380-7384.
61. + gene product in ensuring the selective expression of segment-specific homeotic genes in Drosophila. J. Embryol. exp. Morph. 76, 297-331.
62. Struhl, G. and Basler, K. (1993). Organizing activity of wingless protein in Drosophila. Cell 72, 527-540.
63. Tautz, D. and Pfeifle, C. (1989). A non-radioactive in situ hybridization method for the localization of specific RNAs in Drosophila embryos reveals translational control of the segmentation gene hunchback. Chromosoma 98, 81-85.
64. Villee, C. A. (1944). Phenogenetic studies of the homocotic mutants of Drosophila melanogaster II. The effects of temperature on expression of proboscipedia. J. Exp. Biol. 96, 85-102.
65. Wieschaus, E. and Nüsslein-Volhard (1986). Looking at embryos. In Drosophila: A practical Approach. D. B. Roberts ed. (IRL Oxford) pp 199-228.
66. Xu, T. and Rubin, G. M. (1993). Analysis of genetic mosaics in developing and adult Drosophila tissues. Development 117, 1223-1237.
67. Zecca, M., Basler, K.,and Struhl, G. (1995). Sequential organizing activities of engrailed, hedgehog and decapentaplegic in the Drosophila wing. Development 121, 2265-2278.
68. Zeng, W., Andrews, D. J., Mathies, L. D., Horner, M. A. and Scott, M.P. (1993). Ectopic expression and function of the Antp and Scr homeotic genes: the N terminus of the homeodomain is critical to functional specificity. Development 118, 339-352.