Modular evolution of DNA-binding preference of a tbrain transcription factor provides a mechanism for modifying gene regulatory networks

Molecular Biology and Evolution

Volumn 31, Issue 10, 2014, Pages 2672-2688

  Cheatle Jarvela, Alys M ^a   Brubaker, Lisa ^a   Vedenko, Anastasia ^b   Gupta, Anisha ^a   Armitage, Bruce A ^a   Bulyk, Martha L ^b   Hinman, Veronica F ^a  

^a CARNEGIE MELLON UNIVERSITY   (United States)

^b BRIGHAM AND WOMEN S HOSPITAL   (United States)

Author keywords

echinoderm; evo devo; evolution; gene regulatory networks; T box; transcription factors

Indexed keywords

T BOX TRANSCRIPTION FACTOR; TBRAIN TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG; DNA;

ARTICLE; CRYSTAL STRUCTURE; DNA BINDING MOTIF; DNA LIBRARY; DNA MICROARRAY; DNA MODIFICATION; ECHINODERM; GENE REGULATORY NETWORK; IN VIVO STUDY; MICROARRAY ANALYSIS; MODIFIER GENE; MOLECULAR EVOLUTION; NONHUMAN; ORTHOLOGY; PHYLOGENY; POLYMERASE CHAIN REACTION; PROTEIN-BINDING MICROARRAY; SEA URCHIN; STARFISH; STRONGYLOCENTROTUS PURPURATUS; SURFACE PLASMON RESONANCE; XENOPUS LAEVIS; ANIMAL; BINDING SITE; DNA SEQUENCE; GENETICS; METABOLISM; MOLECULAR GENETICS; PROTEIN MICROARRAY;

ASTERINA MINIATA; ASTEROIDEA; ECHINODERMATA; ECHINOIDEA; STRONGYLOCENTROTUS PURPURATUS;

ANIMALS; BINDING SITES; DNA; EVOLUTION, MOLECULAR; GENE REGULATORY NETWORKS; MOLECULAR SEQUENCE DATA; PHYLOGENY; PROTEIN ARRAY ANALYSIS; SEA URCHINS; SEQUENCE ANALYSIS, DNA; STARFISH; T-BOX DOMAIN PROTEINS;

EID: 84922499223     PISSN: 07374038     EISSN: 15371719     Source Type: Journal    
DOI: 10.1093/molbev/msu213     Document Type: Article

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