메뉴 건너뛰기




Volumn 64, Issue 6, 2014, Pages 1290-1298

Elimination of vitamin D receptor in vascular endothelial cells alters vascular function

Author keywords

Calcitriol; Gene targeting; Hypertension; Receptors; Vitamin D

Indexed keywords

ACETYLCHOLINE; ANGIOTENSIN II; VITAMIN D RECEPTOR; BRAIN NATRIURETIC PEPTIDE; CALCITRIOL RECEPTOR; DNA;

EID: 84922482268     PISSN: 0194911X     EISSN: 15244563     Source Type: Journal    
DOI: 10.1161/HYPERTENSIONAHA.114.03971     Document Type: Article
Times cited : (132)

References (56)
  • 1
    • 34447514029 scopus 로고    scopus 로고
    • Vitamin D deficiency
    • Holick MF. Vitamin D deficiency. N Engl J Med. 2007;357:266-281.
    • (2007) N Engl J Med. , vol.357 , pp. 266-281
    • Holick, M.F.1
  • 2
    • 66749123325 scopus 로고    scopus 로고
    • Improving the measurement of 25-hydroxyvitamin D
    • Wootton AM. Improving the measurement of 25-hydroxyvitamin D. Clin Biochem Rev. 2005;26:33-36.
    • (2005) Clin Biochem Rev. , vol.26 , pp. 33-36
    • Wootton, A.M.1
  • 5
    • 55949086816 scopus 로고    scopus 로고
    • Plasma 25-hydroxyvitamin D levels and risk of incident hypertension among young women
    • Forman JP, Curhan GC, Taylor EN. Plasma 25-hydroxyvitamin D levels and risk of incident hypertension among young women. Hypertension. 2008;52:828-832.
    • (2008) Hypertension , vol.52 , pp. 828-832
    • Forman, J.P.1    Curhan, G.C.2    Taylor, E.N.3
  • 6
    • 84871877598 scopus 로고    scopus 로고
    • 25-hydroxyvitamin d levels and risk of ischemic heart disease, myocardial infarction, and early death: Population-based study and meta-analyses of 18 and 17 studies
    • Brøndum-Jacobsen P, Benn M, Jensen GB, Nordestgaard BG. 25-hydroxyvitamin d levels and risk of ischemic heart disease, myocardial infarction, and early death: population-based study and meta-analyses of 18 and 17 studies. Arterioscler Thromb Vasc Biol. 2012;32:2794-2802.
    • (2012) Arterioscler Thromb Vasc Biol. , vol.32 , pp. 2794-2802
    • Brøndum-Jacobsen, P.1    Benn, M.2    Jensen, G.B.3    Nordestgaard, B.G.4
  • 9
    • 40049088819 scopus 로고    scopus 로고
    • Vitamin D improves endothelial function in patients with Type 2 diabetes mellitus and low vitamin D levels
    • Sugden JA, Davies JI, Witham MD, Morris AD, Struthers AD. Vitamin D improves endothelial function in patients with Type 2 diabetes mellitus and low vitamin D levels. Diabet Med. 2008;25:320-325.
    • (2008) Diabet Med. , vol.25 , pp. 320-325
    • Sugden, J.A.1    Davies, J.I.2    Witham, M.D.3    Morris, A.D.4    Struthers, A.D.5
  • 10
    • 0035027262 scopus 로고    scopus 로고
    • Effects of a short-term vitamin D (3) and calcium supplementation on blood pressure and parathyroid hormone levels in elderly women
    • Pfeifer M, Begerow B, Minne HW, Nachtigall D, Hansen C. Effects of a short-term vitamin D (3) and calcium supplementation on blood pressure and parathyroid hormone levels in elderly women. J Clin Endocrinol Metab. 2001;86:1633-1637.
    • (2001) J Clin Endocrinol Metab. , vol.86 , pp. 1633-1637
    • Pfeifer, M.1    Begerow, B.2    Minne, H.W.3    Nachtigall, D.4    Hansen, C.5
  • 14
    • 0024334463 scopus 로고
    • Identification and regulation of 1, 25-dihydroxyvitamin D3 receptor activity and biosynthesis of 1, 25-dihydroxyvitamin D3. Studies in cultured bovine aortic endothelial cells and human dermal capillaries
    • Merke J, Milde P, Lewicka S, Hügel U, Klaus G, Mangelsdorf DJ, Haussler MR, Rauterberg EW, Ritz E. Identification and regulation of 1, 25-dihydroxyvitamin D3 receptor activity and biosynthesis of 1, 25-dihydroxyvitamin D3. Studies in cultured bovine aortic endothelial cells and human dermal capillaries. J Clin Invest. 1989;83:1903-1915.
    • (1989) J Clin Invest. , vol.83 , pp. 1903-1915
    • Merke, J.1    Milde, P.2    Lewicka, S.3    Hügel, U.4    Klaus, G.5    Mangelsdorf, D.J.6    Haussler, M.R.7    Rauterberg, E.W.8    Ritz, E.9
  • 15
    • 0026042297 scopus 로고
    • 1, 25-dihydroxyvitamin D3 modulates growth of vascular smooth muscle cells
    • Mitsuhashi T, Morris RC Jr, Ives HE. 1, 25-dihydroxyvitamin D3 modulates growth of vascular smooth muscle cells. J Clin Invest. 1991;87:1889-1895.
    • (1991) J Clin Invest. , vol.87 , pp. 1889-1895
    • Mitsuhashi, T.1    Morris, R.C.2    Ives, H.E.3
  • 16
    • 0033870768 scopus 로고    scopus 로고
    • 1 alpha, 25-dihydroxyvitamin D (3) inhibits angiogenesis in vitro and in vivo
    • Mantell DJ, Owens PE, Bundred NJ, Mawer EB, Canfield AE. 1 alpha, 25-dihydroxyvitamin D (3) inhibits angiogenesis in vitro and in vivo. Circ Res. 2000;87:214-220.
    • (2000) Circ Res. , vol.87 , pp. 214-220
    • Mantell, D.J.1    Owens, P.E.2    Bundred, N.J.3    Mawer, E.B.4    Canfield, A.E.5
  • 17
    • 0025151342 scopus 로고
    • Injection of 1, 25-(OH) 2 vitamin D3 enhances resistance artery contractile properties
    • Bukoski RD, Wang DB, Wagman DW. Injection of 1, 25-(OH) 2 vitamin D3 enhances resistance artery contractile properties. Hypertension. 1990;16:523-531.
    • (1990) Hypertension , vol.16 , pp. 523-531
    • Bukoski, R.D.1    Wang, D.B.2    Wagman, D.W.3
  • 18
    • 0033035998 scopus 로고    scopus 로고
    • Recovery of impaired K+ channels in mesenteric arteries from spontaneously hypertensive rats by prolonged treatment with cholecalciferol
    • Borges AC, Feres T, Vianna LM, Paiva TB. Recovery of impaired K+ channels in mesenteric arteries from spontaneously hypertensive rats by prolonged treatment with cholecalciferol. Br J Pharmacol. 1999;127:772-778.
    • (1999) Br J Pharmacol. , vol.127 , pp. 772-778
    • Borges, A.C.1    Feres, T.2    Vianna, L.M.3    Paiva, T.B.4
  • 19
    • 0032757555 scopus 로고    scopus 로고
    • Effect of cholecalciferol treatment on the relaxant responses of spontaneously hypertensive rat arteries to acetylcholine
    • Borges AC, Feres T, Vianna LM, Paiva TB. Effect of cholecalciferol treatment on the relaxant responses of spontaneously hypertensive rat arteries to acetylcholine. Hypertension. 1999;34(4 pt 2):897-901.
    • (1999) Hypertension , vol.34 , Issue.4 , pp. 897-901
    • Borges, A.C.1    Feres, T.2    Vianna, L.M.3    Paiva, T.B.4
  • 20
    • 33947497538 scopus 로고    scopus 로고
    • Endothelial dysfunction: Cardiovascular risk factors, therapy, and outcome
    • Hadi HA, Carr CS, Al Suwaidi J. Endothelial dysfunction: cardiovascular risk factors, therapy, and outcome. Vasc Health Risk Manag. 2005;1:183-198.
    • (2005) Vasc Health Risk Manag. , vol.1 , pp. 183-198
    • Hadi, H.A.1    Carr, C.S.2    Al Suwaidi, J.3
  • 22
    • 29944436856 scopus 로고    scopus 로고
    • Endothelial FAK is essential for vascular network stability, cell survival, and lamellipodial formation
    • Braren R, Hu H, Kim YH, Beggs HE, Reichardt LF, Wang R. Endothelial FAK is essential for vascular network stability, cell survival, and lamellipodial formation. J Cell Biol. 2006;172:151-162.
    • (2006) J Cell Biol. , vol.172 , pp. 151-162
    • Braren, R.1    Hu, H.2    Kim, Y.H.3    Beggs, H.E.4    Reichardt, L.F.5    Wang, R.6
  • 23
    • 49849085584 scopus 로고    scopus 로고
    • Vitamin D derivatives acutely reduce endothelium-dependent contractions in the aorta of the spontaneously hypertensive rat
    • Wong MS, Delansorne R, Man RY, Vanhoutte PM. Vitamin D derivatives acutely reduce endothelium-dependent contractions in the aorta of the spontaneously hypertensive rat. Am J Physiol Heart Circ Physiol. 2008;295:H289-H296.
    • (2008) Am J Physiol Heart Circ Physiol. , vol.295 , pp. H289-H296
    • Wong, M.S.1    Delansorne, R.2    Man, R.Y.3    Vanhoutte, P.M.4
  • 24
    • 0031755168 scopus 로고    scopus 로고
    • Current understanding of the molecular actions of vitamin D
    • Jones G, Strugnell SA, De Luca HF. Current understanding of the molecular actions of vitamin D. Physiol Rev. 1998;78:1193-1231.
    • (1998) Physiol Rev. , vol.78 , pp. 1193-1231
    • Jones, G.1    Strugnell, S.A.2    De Luca, H.F.3
  • 25
    • 79952206275 scopus 로고    scopus 로고
    • Vitamin d receptor activation mitigates the impact of uremia on endothelial function in the 5/6 nephrectomized rats
    • Wu-Wong JR, Noonan W, Nakane M, Brooks KA, Segreti JA, Polakowski JS, Cox B. Vitamin d receptor activation mitigates the impact of uremia on endothelial function in the 5/6 nephrectomized rats. Int J Endocrinol. 2010;2010:625852.
    • (2010) Int J Endocrinol. , vol.2010 , pp. 625852
    • Wu-Wong, J.R.1    Noonan, W.2    Nakane, M.3    Brooks, K.A.4    Segreti, J.A.5    Polakowski, J.S.6    Cox, B.7
  • 26
    • 66749143724 scopus 로고    scopus 로고
    • Endothelin ET (B) receptors in arteries and veins: Multiple actions in the vein
    • Tykocki NR, Gariepy CE, Watts SW. Endothelin ET (B) receptors in arteries and veins: multiple actions in the vein. J Pharmacol Exp Ther. 2009;329:875-881.
    • (2009) J Pharmacol Exp Ther. , vol.329 , pp. 875-881
    • Tykocki, N.R.1    Gariepy, C.E.2    Watts, S.W.3
  • 28
    • 80053539465 scopus 로고    scopus 로고
    • Modulators of the vascular endothelin receptor in blood pressure regulation and hypertension
    • Khalil RA. Modulators of the vascular endothelin receptor in blood pressure regulation and hypertension. Curr Mol Pharmacol. 2011;4:176-186.
    • (2011) Curr Mol Pharmacol. , vol.4 , pp. 176-186
    • Khalil, R.A.1
  • 29
    • 84860809498 scopus 로고    scopus 로고
    • CARD-024, a vitamin D analog, attenuates the pro-fbrotic response to substrate stiffness in colonic myofbroblasts
    • Johnson LA, Sauder KL, Rodansky ES, Simpson RU, Higgins PD. CARD-024, a vitamin D analog, attenuates the pro-fbrotic response to substrate stiffness in colonic myofbroblasts. Exp Mol Pathol. 2012;93:91-98.
    • (2012) Exp Mol Pathol. , vol.93 , pp. 91-98
    • Johnson, L.A.1    Sauder, K.L.2    Rodansky, E.S.3    Simpson, R.U.4    Higgins, P.D.5
  • 32
    • 79953682240 scopus 로고    scopus 로고
    • The role of oxidative stress in the pathophysiology of hypertension
    • Rodrigo R, González J, Paoletto F. The role of oxidative stress in the pathophysiology of hypertension. Hypertens Res. 2011;34:431-440.
    • (2011) Hypertens Res. , vol.34 , pp. 431-440
    • Rodrigo, R.1    González, J.2    Paoletto, F.3
  • 33
    • 0035015769 scopus 로고    scopus 로고
    • Characterization of a novel EGFP reporter mouse to monitor Cre recombination as demonstrated by a Tie2 Cre mouse line
    • Constien R, Forde A, Liliensiek B, Gröne HJ, Nawroth P, Hämmerling G, Arnold B. Characterization of a novel EGFP reporter mouse to monitor Cre recombination as demonstrated by a Tie2 Cre mouse line. Genesis. 2001;30:36-44.
    • (2001) Genesis. , vol.30 , pp. 36-44
    • Constien, R.1    Forde, A.2    Liliensiek, B.3    Gröne, H.J.4    Nawroth, P.5    Hämmerling, G.6    Arnold, B.7
  • 35
    • 0035902572 scopus 로고    scopus 로고
    • Angiotensin II type 2 receptor is essential for left ventricular hypertrophy and cardiac fibrosis in chronic angiotensin II-induced hypertension
    • Ichihara S, Senbonmatsu T, Price E Jr, Ichiki T, Gaffney FA, Inagami T. Angiotensin II type 2 receptor is essential for left ventricular hypertrophy and cardiac fibrosis in chronic angiotensin II-induced hypertension. Circulation. 2001;104:346-351.
    • (2001) Circulation , vol.104 , pp. 346-351
    • Ichihara, S.1    Senbonmatsu, T.2    Price, E.3    Ichiki, T.4    Gaffney, F.A.5    Inagami, T.6
  • 36
    • 34548634762 scopus 로고    scopus 로고
    • Vitamin D supplementation and total mortality: A meta-analysis of randomized controlled trials
    • Autier P, Gandini S. Vitamin D supplementation and total mortality: a meta-analysis of randomized controlled trials. Arch Intern Med. 2007;167:1730-1737.
    • (2007) Arch Intern Med. , vol.167 , pp. 1730-1737
    • Autier, P.1    Gandini, S.2
  • 37
    • 77950359814 scopus 로고    scopus 로고
    • Systematic review: Vitamin D and calcium supplementation in prevention of cardiovascular events
    • Wang L, Manson JE, Song Y, Sesso HD. Systematic review: Vitamin D and calcium supplementation in prevention of cardiovascular events. Ann Intern Med. 2010;152:315-323.
    • (2010) Ann Intern Med. , vol.152 , pp. 315-323
    • Wang, L.1    Manson, J.E.2    Song, Y.3    Sesso, H.D.4
  • 39
    • 77952759256 scopus 로고    scopus 로고
    • Vitamin D status and arterial hypertension: A systematic review
    • Pilz S, Tomaschitz A, Ritz E, Pieber TR. Vitamin D status and arterial hypertension: a systematic review. Nat Rev Cardiol. 2009;6:621-630.
    • (2009) Nat Rev Cardiol. , vol.6 , pp. 621-630
    • Pilz, S.1    Tomaschitz, A.2    Ritz, E.3    Pieber, T.R.4
  • 40
    • 45149090726 scopus 로고    scopus 로고
    • 25-hydroxyvitamin D and risk of myocardial infarction in men: A prospective study
    • Giovannucci E, Liu Y, Hollis BW, Rimm EB. 25-hydroxyvitamin D and risk of myocardial infarction in men: a prospective study. Arch Intern Med. 2008;168:1174-1180.
    • (2008) Arch Intern Med. , vol.168 , pp. 1174-1180
    • Giovannucci, E.1    Liu, Y.2    Hollis, B.W.3    Rimm, E.B.4
  • 43
    • 4143096123 scopus 로고    scopus 로고
    • Disruption of nuclear vitamin D receptor gene causes enhanced thrombogenicity in mice
    • Aihara K, Azuma H, Akaike M, et al. Disruption of nuclear vitamin D receptor gene causes enhanced thrombogenicity in mice. J Biol Chem. 2004;279:35798-35802.
    • (2004) J Biol Chem. , vol.279 , pp. 35798-35802
    • Aihara, K.1    Azuma, H.2    Akaike, M.3
  • 45
    • 58049199370 scopus 로고    scopus 로고
    • A calcimimetic (R-568), but not calcitriol, prevents vascular remodeling in uremia
    • Koleganova N, Piecha G, Ritz E, Schmitt CP, Gross ML. A calcimimetic (R-568), but not calcitriol, prevents vascular remodeling in uremia. Kidney Int. 2009;75:60-71.
    • (2009) Kidney Int. , vol.75 , pp. 60-71
    • Koleganova, N.1    Piecha, G.2    Ritz, E.3    Schmitt, C.P.4    Gross, M.L.5
  • 47
    • 78650849973 scopus 로고    scopus 로고
    • 25-Hydroxyvitamin D deficiency is associated with infammationlinked vascular endothelial dysfunction in middle-aged and older adults
    • Jablonski KL, Chonchol M, Pierce GL, Walker AE, Seals DR. 25-Hydroxyvitamin D deficiency is associated with infammationlinked vascular endothelial dysfunction in middle-aged and older adults. Hypertension. 2011;57:63-69.
    • (2011) Hypertension , vol.57 , pp. 63-69
    • Jablonski, K.L.1    Chonchol, M.2    Pierce, G.L.3    Walker, A.E.4    Seals, D.R.5
  • 48
    • 0037432301 scopus 로고    scopus 로고
    • Changes in brain natriuretic peptide and norepinephrine over time and mortality and morbidity in the Valsartan Heart Failure Trial (Val-HeFT)
    • Anand IS, Fisher LD, Chiang YT, Latini R, Masson S, Maggioni AP, Glazer RD, Tognoni G, Cohn JN; Val-HeFT Investigators. Changes in brain natriuretic peptide and norepinephrine over time and mortality and morbidity in the Valsartan Heart Failure Trial (Val-HeFT). Circulation. 2003;107:1278-1283.
    • (2003) Circulation , vol.107 , pp. 1278-1283
    • Anand, I.S.1    Fisher, L.D.2    Chiang, Y.T.3    Latini, R.4    Masson, S.5    Maggioni, A.P.6    Glazer, R.D.7    Tognoni, G.8    Cohn, J.N.9
  • 49
    • 77953021953 scopus 로고    scopus 로고
    • Early detection of myocardial dysfunction and heart failure
    • De Couto G, Ouzounian M, Liu PP. Early detection of myocardial dysfunction and heart failure. Nat Rev Cardiol. 2010;7:334-344.
    • (2010) Nat Rev Cardiol. , vol.7 , pp. 334-344
    • De Couto, G.1    Ouzounian, M.2    Liu, P.P.3
  • 50
    • 84869048064 scopus 로고    scopus 로고
    • Modest elevation in BNP in asymptomatic hypertensive patients refects sub-clinical cardiac remodeling, infammation and extracellular matrix changes
    • Phelan D, Watson C, Martos R, Collier P, Patle A, Donnelly S, Ledwidge M, Baugh J, McDonald K. Modest elevation in BNP in asymptomatic hypertensive patients refects sub-clinical cardiac remodeling, infammation and extracellular matrix changes. PLoS One. 2012;7:e49259.
    • (2012) PLoS One. , vol.7 , pp. e49259
    • Phelan, D.1    Watson, C.2    Martos, R.3    Collier, P.4    Patle, A.5    Donnelly, S.6    Ledwidge, M.7    Baugh, J.8    McDonald, K.9
  • 51
    • 63249131125 scopus 로고    scopus 로고
    • Endothelium-driven myocardial growth or nitric oxide at the crossroads
    • Tirziu D, Simons M. Endothelium-driven myocardial growth or nitric oxide at the crossroads. Trends Cardiovasc Med. 2008;18:299-305.
    • (2008) Trends Cardiovasc Med. , vol.18 , pp. 299-305
    • Tirziu, D.1    Simons, M.2
  • 52
    • 55449117365 scopus 로고    scopus 로고
    • The cardiac microvasculature in hypertension, cardiac hypertrophy and diastolic heart failure
    • Hoenig MR, Bianchi C, Rosenzweig A, Sellke FW. The cardiac microvasculature in hypertension, cardiac hypertrophy and diastolic heart failure. Curr Vasc Pharmacol. 2008;6:292-300.
    • (2008) Curr Vasc Pharmacol. , vol.6 , pp. 292-300
    • Hoenig, M.R.1    Bianchi, C.2    Rosenzweig, A.3    Sellke, F.W.4
  • 54
    • 84865663428 scopus 로고    scopus 로고
    • Calcitriol protects renovascular function in hypertension by down-regulating angiotensin II type 1 receptors and reducing oxidative stress
    • Dong J, Wong SL, Lau CW, Lee HK, Ng CF, Zhang L, Yao X, Chen Z Y, Vanhoutte PM, Huang Y. Calcitriol protects renovascular function in hypertension by down-regulating angiotensin II type 1 receptors and reducing oxidative stress. Eur Heart J. 2012;33:2980-2990.
    • (2012) Eur Heart J. , vol.33 , pp. 2980-2990
    • Dong, J.1    Wong, S.L.2    Lau, C.W.3    Lee, H.K.4    Ng, C.F.5    Zhang, L.6    Yao, X.7    Chen, Z.Y.8    Vanhoutte, P.M.9    Huang, Y.10


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.