MicroRNA-451 induces epithelial-mesenchymal transition in docetaxel-resistant lung adenocarcinoma cells by targeting proto-oncogene c-Myc

European Journal of Cancer

Volumn 50, Issue 17, 2014, Pages 3050-3067

  Chen, Dongqin ^a   Huang, Jiayuan ^a   Zhang, Kai ^a   Pan, Banzhou ^a   Chen, Jing ^a   De, Wei ^b   Wang, Rui ^a   Chen, Longbang ^a  

^a NANJING UNIVERSITY   (China)

^b NANJING MEDICAL UNIVERSITY   (China)

Author keywords

c Myc; Chemoresistance; Epithelial mesenchymal transition; Invasion; Lung adenocarcinoma; Metastasis; miR 451

Indexed keywords

8 [4 (1 AMINOCYCLOBUTYL)PHENYL] 9 PHENYL 1,2,4 TRIAZOLO[3,4 F][1,6]NAPHTHYRIDIN 3(2H) ONE; CARBOPLATIN; CISPLATIN; DOCETAXEL; GLYCOGEN SYNTHASE KINASE 3BETA; MICRORNA; MICRORNA 451; MITOGEN ACTIVATED PROTEIN KINASE; PACLITAXEL; PLASMID VECTOR; TRANSCRIPTION FACTOR SNAIL; UNCLASSIFIED DRUG; ANTINEOPLASTIC AGENT; MIRN451 MICRORNA, HUMAN; MYC PROTEIN; TAXOID;

ADENOCARCINOMA CELL LINE; ADVANCED CANCER; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER COMBINATION CHEMOTHERAPY; CANCER PROGNOSIS; CANCER RESISTANCE; CELL INVASION; CELL MIGRATION; CONTROLLED STUDY; DOWN REGULATION; DRUG MECHANISM; ENZYME INACTIVATION; EPITHELIAL MESENCHYMAL TRANSITION; FEMALE; GENE LOSS; GENE OVEREXPRESSION; GENE TARGETING; HUMAN; HUMAN CELL; HUMAN TISSUE; IC50; LUNG ADENOCARCINOMA; LYMPH NODE METASTASIS; MOUSE; MTT ASSAY; MULTIPLE CYCLE TREATMENT; NONHUMAN; ONCOGENE C MYC; PHENOTYPE; PRIORITY JOURNAL; PROTO ONCOGENE; SIGNAL TRANSDUCTION; TUMOR DIFFERENTIATION; UPREGULATION; WESTERN BLOTTING; ADENOCARCINOMA; AGED; DRUG EFFECTS; DRUG RESISTANCE; GENE SILENCING; GENETICS; LUNG NEOPLASMS; MALE; PATHOLOGY; TUMOR CELL LINE;

ADENOCARCINOMA; AGED; ANTINEOPLASTIC AGENTS; CELL LINE, TUMOR; DRUG RESISTANCE, NEOPLASM; EPITHELIAL-MESENCHYMAL TRANSITION; FEMALE; GENE SILENCING; HUMANS; LUNG NEOPLASMS; MALE; MICRORNAS; PROTO-ONCOGENE PROTEINS C-MYC; TAXOIDS;

EID: 84922482158     PISSN: 09598049     EISSN: 18790852     Source Type: Journal    
DOI: 10.1016/j.ejca.2014.09.008     Document Type: Article

References (47)

1. A. Jemal, R. Siegel, J. Xu, and E. Ward Cancer statistics, 2010 CA Cancer J Clin 60 5 2010 277 300
2. S. Gettinger, and T. Lynch A decade of advances in treatment for advanced non-small cell lung cancer Clin Chest Med 32 4 2011 839 851
3. M. Iwatsuki, K. Mimori, and T. Yokobori Epithelial-mesenchymal transition in cancer development and its clinical significance Cancer Sci 101 2 2010 293 299
4. F. Meng, and G. Wu The rejuvenated scenario of epithelial-mesenchymal transition (EMT) and cancer metastasis Cancer Metastasis Rev 31 3-4 2012 455 467
5. K. Harada, T. Ferdous, and Y. Ueyama Establishment of 5-fluorouracil-resistant oral squamous cell carcinoma cell lines with epithelial to mesenchymal transition changes Int J Oncol 44 4 2014 1302 1308
6. M. Puhr, J. Hoefer, and G. Schäfer Epithelial-to-mesenchymal transition leads to docetaxel resistance in prostate cancer and is mediated by reduced expression of miR-200c and miR-205 Am J Pathol 181 6 2012 2188 2201
7. S. Marchini, R. Fruscio, and L. Clivio Resistance to platinum-based chemotherapy is associated with epithelial to mesenchymal transition in epithelial ovarian cancer Eur J Cancer 49 2 2013 520 530
8. H. Liu, H.W. Zhang, and X.F. Sun Tamoxifen-resistant breast cancer cells possess cancer stem-like cell properties Chin Med J (Engl) 126 16 2013 3030 3034
9. L.A. Byers, L. Diao, and J. Wang An epithelial-mesenchymal transition gene signature predicts resistance to EGFR and PI3K inhibitors and identifies Axl as a therapeutic target for overcoming EGFR inhibitor resistance Clin Cancer Res 19 1 2013 279 290
10. C. Oliveras-Ferraros, B. Corominas-Faja, and S. Cufí Epithelial-to-mesenchymal transition (EMT) confers primary resistance to trastuzumab (Herceptin) Cell Cycle 11 21 2012 4020 4032
11. E. Sánchez-Tilló, Y. Liu, and O. de Barrios EMT-activating transcription factors in cancer: beyond EMT and tumor invasiveness Cell Mol Life Sci 69 20 2012 3429 3456
12. S. Lamouille, J. Xu, and R. Derynck Molecular mechanisms of epithelial-mesenchymal transition Nat Rev Mol Cell Biol 15 3 2014 178 196
13. X.S. Ke, C.M. Liu, and D.P. Liu MicroRNAs: key participants in gene regulatory networks Curr Opin Chem Biol 7 4 2003 516 523
14. J.T. Mendell, and E.N. Olson MicroRNAs in stress signaling and human disease Cell 148 6 2012 1172 1187
15. D.A. Chistiakov, and V.P. Chekhonin Contribution of microRNAs to radio- and chemoresistance of brain tumors and their therapeutic potential Eur J Pharmacol 684 1-3 2012 8 18
16. S. Lamouille, D. Subramanyam, and R. Blelloch Regulation of epithelial-mesenchymal and mesenchymal-epithelial transitions by microRNAs Curr Opin Cell Biol 25 2 2013 200 207
17. R.U. Takahashi, H. Miyazaki, and T. Ochiya The role of microRNAs in the regulation of cancer stem cells Front Genet 4 2014 295
18. W. Rui, F. Bing, and S. Hai-Zhu Identification of microRNA profiles in docetaxel-resistant human non-small cell lung carcinoma cells (SPC-A1) J Cell Mol Med 14 1-2 2010 206 214
19. B. Feng, R. Wang, and H.Z. Song MicroRNA-200b reverses chemoresistance of docetaxel-resistant human lung adenocarcinoma cells by targeting E2F3 Cancer 118 13 2011 3365 3376
20. B. Feng, R. Wang, and L.B. Chen MiR-100 resensitizes docetaxel-resistant human lung adenocarcinoma cells (SPC-A1) to docetaxel by targeting Plk1 Cancer Lett 317 2 2012 184 191
21. S.Y. Cui, J.Y. Huang, and Y.T. Chen Let-7c governs the acquisition of chemo- or radioresistance and epithelial-to-mesenchymal transition phenotypes in docetaxel-resistant lung adenocarcinoma Mol Cancer Res 11 7 2013 699 713
22. J.Y. Huang, S.Y. Cui, and Y.T. Chen MicroRNA-650 was a prognostic factor in human lung adenocarcinoma and confers the docetaxel chemoresistance of lung adenocarcinoma cells via regulating Bcl-2/Bax expression PLoS One 8 8 2013 e72615
23. M. Cao, M. Seike, and C. Soeno MiR-23a regulates TGF-β-induced epithelial-mesenchymal transition by targeting E-cadherin in lung cancer cells Int J Oncol 41 3 2012 869 875
24. K. Kitamura, M. Seike, and T. Okano MiR-134/487b/655 cluster regulates TGF-β-induced epithelial-mesenchymal transition and drug resistance to gefitinib by targeting MAGI2 in lung adenocarcinoma cells Mol Cancer Ther 13 2 2014 444 453
25. R. Wang, Z.X. Wang, and J.S. Yang MicroRNA-451 functions as a tumor suppressor in human non-small cell lung cancer by targeting ras-related protein 14 (RAB14) Oncogene 30 23 2011 2644 2658
26. D. Olmeda, M. Jordá, and H. Peinado Snail silencing effectively suppresses tumour growth and invasiveness Oncogene 26 13 2007 1862 1874
27. Q. Ding, W. Xia, and J.C. Liu Erk associates with and primes GSK-3beta for its inactivation resulting in upregulation of beta-catenin Mol Cell 19 2 2005 159 170
28. J. Zhong, M.M. Gencay, and L. Bubendorf ERK1/2 and p38 MAP kinase control MMP-2, MT1-MMP, and TIMP action and affect cell migration: a comparison between mesothelioma and mesothelial cells J Cell Physiol 207 2 2006 540 552
29. A.D. Yang, F. Fan, and E.R. Camp Chronic oxaliplatin resistance induces epithelial-to-mesenchymal transition in colorectal cancer cell lines Clin Cancer Res 12 14 Pt 1 2006 4147 4153
30. Q. Yang, J. Huang, and Q. Wu Acquisition of epithelial-mesenchymal transition is associated with Skp2 expression in paclitaxel-resistant breast cancer cells Br J Cancer 110 8 2014 1958 1967
31. S. Hiscox, W.G. Jiang, and K. Obermeier Tamoxifen resistance in MCF7 cells promotes EMT-like behaviour and involves modulation of beta-catenin phosphorylation Int J Cancer 118 2 2006 290 301
32. V. Mele, M.G. Muraro, and D. Calabrese Mesenchymal stromal cells induce epithelial-to-mesenchymal transition in human colorectal cancer cells through the expression of surface-bound TGF-β Int J Cancer 134 11 2014 2583 2594
33. Q. Wu, R. Wang, and Q. Yang Chemoresistance to gemcitabine in hepatoma cells induces epithelial-mesenchymal transition and involves activation of PDGF-D pathway Oncotarget 4 11 2013 1999 2009
34. H. Wang, G. Zhang, and H. Zhang Acquisition of epithelial-mesenchymal transition phenotype and cancer stem cell-like properties in cisplatin-resistant lung cancer cells through AKT/β-catenin/Snail signaling pathway Eur J Pharmacol 723 2014 156 166
35. J. Ma, C. Dong, and C. Ji MicroRNA and drug resistance Cancer Gene Ther 17 8 2010 523 531
36. J. Godlewski, A. Bronisz, and M.O. Nowicki MicroRNA-451: a conditional switch controlling glioma cell proliferation and migration Cell Cycle 9 14 2010 2742 2748
37. H.P. Li, X.C. Zeng, and B. Zhang MiR-451 inhibits cell proliferation in human hepatocellular carcinoma through direct suppression of IKK-β Carcinogenesis 34 11 2013 2443 2451
38. X. Li, T. Sanda, A.T. Look, and C.D. Novina Repression of tumor suppressor miR-451 is essential for NOTCH1-induced oncogenesis in T-ALL J Exp Med 208 4 2011 663 675
39. J. Godlewski, M.O. Nowicki, and A. Bronisz MicroRNA-451 regulates LKB1/AMPK signaling and allows adaptation to metabolic stress in glioma cells Mol Cell 37 5 2010 620 632
40. O. Kovalchuk, J. Filkowski, and J. Meservy Involvement of microRNA-451 in resistance of the MCF-7 breast cancer cells to chemotherapeutic drug doxorubicin Mol Cancer Ther 7 7 2008 2152 2159
41. E. Bandres, N. Bitarte, and F. Arias MicroRNA-451 regulates macrophage migration inhibitory factor production and proliferation of gastrointestinal cancer cells Clin Cancer Res 15 7 2009 2281 2290
42. H.B. Bian, X. Pan, and J.S. Yang Upregulation of microRNA-451 increases cisplatin sensitivity of non-small cell lung cancer cell line (A549) J Exp Clin Cancer Res 30 2011 20
43. N. Bitarte, E. Bandres, and V. Boni MicroRNA-451 is involved in the self-renewal, tumorigenicity, and chemoresistance of colorectal cancer stem cells Stem Cells 29 11 2011 1661 1671
44. C.V. Dang MYC on the path to cancer Cell 149 1 2012 22 35
45. T.A. Brooks, and L.H. Hurley The role of supercoiling in transcriptional control of MYC and its importance in molecular therapeutics Nat Rev Cancer 9 12 2009 849 861
46. K.B. Cho, M.K. Cho, and W.Y. Lee Overexpression of c-myc induces epithelial mesenchymal transition in mammary epithelial cells Cancer Lett 293 2 2010 230 239
47. M.D. Amatangelo, S. Goodyear, and D. Varma C-Myc expression and MEK1-induced Erk2 nuclear localization are required for TGF-beta induced epithelial-mesenchymal transition and invasion in prostate cancer Carcinogenesis 33 10 2012 1965 1975