Downregulation of spleen tyrosine kinase in hepatocellular carcinoma by promoter CpG island hypermethylation and its potential role in carcinogenesis

Laboratory Investigation

Volumn 94, Issue 12, 2014, Pages 1396-1405

  Shin, So Hyun ^a   Lee, Kwang Ho ^b   Kim, Baek Hee ^c   Lee, Sun ^d   Lee, Hwan Seok ^e   Jang, Ja June ^e   Kang, Gyeong Hoon ^a,e  

^a Seoul National University Graduate School   (South Korea)

^b UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^c Korea University   (South Korea)

^d Kyung Hee University   (South Korea)

^e Seoul National University College of Medicine   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

FIBRONECTIN; PROTEIN KINASE SYK; RNA; BETA1 INTEGRIN; PROTEIN TYROSINE KINASE; SIGNAL PEPTIDE;

ADULT; AGED; ARTICLE; CANCER PROGNOSIS; CARCINOGENESIS; CELL ADHESION; CELL INVASION; CELL MIGRATION; CELL PROLIFERATION; CLINICAL ARTICLE; CONTROLLED STUDY; CORRELATION ANALYSIS; CPG ISLAND; DNA METHYLATION; EXPRESSION VECTOR; FEMALE; GENE EXPRESSION; GENE ONTOLOGY; HEPATOCELLULAR CARCINOMA CELL LINE; HUMAN; HUMAN CELL; HUMAN TISSUE; LIVER CELL CARCINOMA; MALE; OVERALL SURVIVAL; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; ANTAGONISTS AND INHIBITORS; CARCINOMA, HEPATOCELLULAR; DOWN REGULATION; ENZYMOLOGY; GENE EXPRESSION PROFILING; GENETICS; LIVER NEOPLASMS; MIDDLE AGED; MORTALITY; PHYSIOLOGY; SPLEEN; TUMOR CELL LINE; TUMOR INVASION;

ADULT; AGED; ANTIGENS, CD29; CARCINOGENESIS; CARCINOMA, HEPATOCELLULAR; CELL LINE, TUMOR; CELL PROLIFERATION; CPG ISLANDS; DNA METHYLATION; DOWN-REGULATION; FEMALE; GENE EXPRESSION PROFILING; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; LIVER NEOPLASMS; MALE; MIDDLE AGED; NEOPLASM INVASIVENESS; PROMOTER REGIONS, GENETIC; PROTEIN-TYROSINE KINASES; SPLEEN;

EID: 84922480329     PISSN: 00236837     EISSN: 15300307     Source Type: Journal    
DOI: 10.1038/labinvest.2014.118     Document Type: Article

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