Dietary Pectin-Derived Acidic Oligosaccharides Improve the Pulmonary Bacterial Clearance of Pseudomonas aeruginosa Lung Infection in Mice by Modulating Intestinal Microbiota and Immunity

Journal of Infectious Diseases

Volumn 211, Issue 1, 2015, Pages 156-165

  Bernard, Henry ^a,b   Desseyn, Jean Luc ^a,c   Bartke, Nana ^a,b   Kleinjans, Lennart ^b   Stahl, Bernd ^c   Belzer, Clara ^a   Knol, Jan ^a   Gottrand, Frédéric ^b   Husson, Marie Odile ^a  

^a UNIVERSITÉ DE LILLE   (France)

^b Nutricia Nederland   (Netherlands)

^c WAGENINGEN UNIVERSITY   (Netherlands)

Author keywords

intestinal microbiota; P. aeruginosa lung infection.; prebiotics; Th1 and M1 polarization

Indexed keywords

BUTYRIC ACID; CYTOKINE; GAMMA INTERFERON; INTERLEUKIN 10; INTERLEUKIN 4; KERATINOCYTE CHEMOATTRACTANT; OLIGOSACCHARIDE; PECTIN DERIVED ACIDIC OLIGOSACCHARIDE; PROPIONIC ACID; TRANSCRIPTION FACTOR GATA 3; TRANSCRIPTION FACTOR T BET; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; CHEMOTACTIC FACTOR; GATA3 PROTEIN, MOUSE; IL10 PROTEIN, MOUSE; PECTIN; T BOX TRANSCRIPTION FACTOR; T-BOX TRANSCRIPTION FACTOR TBX21;

ALLOBACULUM; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BACTERIAL CLEARANCE; BACTERIAL GROWTH; BACTERIAL IMMUNITY; BACTEROIDES VULGATUS; BIFIDOBACTERIUM; CLOSTRIDIUM; CLOSTRIDIUM SPHENOIDES; CONTROLLED STUDY; CYTOKINE RELEASE; DIET SUPPLEMENTATION; DOWN REGULATION; ERYSIPELATOCLOSTRIDIUM RAMOSUM; ESCHERICHIA COLI; GATA3 GENE; GENE EXPRESSION; IMMUNOMODULATION; INFLAMMATION; INTESTINE FLORA; LUNG INFECTION; MACROPHAGE ACTIVATION; MALE; MOUSE; NEUTROPHIL; NONHUMAN; PEPTOCLOSTRIDIUM DIFFICILE; PSEUDOMONAS INFECTION; SUTTURELLA WADSWORTHIA; T BET GENE; TH1 CELL; UPREGULATION; ANIMAL; BAGG ALBINO MOUSE; CHEMISTRY; DRUG EFFECTS; GROWTH, DEVELOPMENT AND AGING; IMMUNOLOGY; INTESTINE; KERATINOCYTE; LEUKOCYTE; LUNG DISEASES; MACROPHAGE; MICROBIOLOGY; MICROFLORA; PSEUDOMONAS AERUGINOSA; PSEUDOMONAS INFECTIONS;

ANIMALS; CHEMOTACTIC FACTORS; GATA3 TRANSCRIPTION FACTOR; INTERFERON-GAMMA; INTERLEUKIN-10; INTERLEUKIN-4; INTESTINES; KERATINOCYTES; LEUKOCYTES; LUNG DISEASES; MACROPHAGES; MALE; MICE; MICE, INBRED BALB C; MICROBIOTA; OLIGOSACCHARIDES; PECTINS; PSEUDOMONAS AERUGINOSA; PSEUDOMONAS INFECTIONS; T-BOX DOMAIN PROTEINS; TH1 CELLS; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84922439272     PISSN: 00221899     EISSN: 15376613     Source Type: Journal    
DOI: 10.1093/infdis/jiu391     Document Type: Article

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