CPSF30 and Wdr33 directly bind to AAUAAA in mammalian mRNA 3′ processing

Genes and Development

Volumn 28, Issue 21, 2014, Pages 2370-2380

  Chan, Serena L ^a   Huppertz, Ina ^b,c   Yao, Chengguo ^a   Weng, Lingjie ^a,d,e   Moresco, James J ^f   Yates, John R ^f   Ule, Jernej ^b,c   Manley, James L ^g   Shi, Yongsheng ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY COLLEGE LONDON   (United Kingdom)

^c MRC LABORATORY OF MOLECULAR BIOLOGY   (United Kingdom)

^d Institute for Genomics and Bioinformatics   (United States)

^e UNIVERSITY OF CALIFORNIA   (United States)

^f SCRIPPS RESEARCH INSTITUTE   (United States)

^g Och Spine at New York Presbyterian Hospitals   (United States)

Author keywords

Cleavage and polyadenylation; MRNA 3 processing; Polyadenylation signal

Indexed keywords

CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR; CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR 30; MESSENGER RNA; RNA BINDING PROTEIN; TRANSCRIPTOME; UNCLASSIFIED DRUG; ZINC FINGER PROTEIN; CPSF30 PROTEIN, HUMAN; NUCLEAR PROTEIN; PROTEIN BINDING; WDR33 PROTEIN, HUMAN;

AMINO ACID SEQUENCE; ARTICLE; GEL MOBILITY SHIFT ASSAY; GENE; HUMAN; HUMAN CELL; IMMUNOPRECIPITATION; IN VITRO STUDY; IN VIVO STUDY; MAMMALIAN GENETICS; NUCLEOTIDE SEQUENCE; PEPTIDE MAPPING; POLYADENYLATION; PROTEIN RNA BINDING; STOICHIOMETRY; ULTRAVIOLET IRRADIATION; WDR33 GENE; WESTERN BLOTTING; GENE EXPRESSION PROFILING; HEK293 CELL LINE; HELA CELL LINE; METABOLISM; PHYSIOLOGY; PROTEIN MOTIF; PROTEIN TERTIARY STRUCTURE; RNA PROCESSING;

AMINO ACID MOTIFS; CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR; GENE EXPRESSION PROFILING; HEK293 CELLS; HELA CELLS; HUMANS; NUCLEAR PROTEINS; POLYADENYLATION; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; RNA 3' END PROCESSING; RNA, MESSENGER;

EID: 84922392412     PISSN: 08909369     EISSN: 15495477     Source Type: Journal    
DOI: 10.1101/gad.250993.114     Document Type: Article

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