Endo-β-n-acetylglucosaminidase forms N-GlcNAc protein aggregates during ER-associated degradation in NGLY1-defective cells

Proceedings of the National Academy of Sciences of the United States of America

Volumn 112, Issue 5, 2015, Pages 1398-1403

  Suzuki, Tadashi ^a,b   Huang, Chengcheng ^a,b   Harada, Yoichiro ^a   Hosomi, Akira ^a   Masahara Negishi, Yuki ^a   Seino, Junichi ^a   Fujihira, Haruhiko ^a   Funakoshi, Yoko ^a   Suzuki, Takehiro ^a   Dohmae, Naoshi ^a  

^a RIKEN   (Japan)

^b SAITAMA UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

GLYCOPROTEIN; N ACETYL BETA GLUCOSAMINIDASE; N ACETYLGLUCOSAMINE; PROTEIN AGGREGATE; GLYCOPEPTIDASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CONFORMATION; CONTROLLED STUDY; DEGLYCOSYLATION; EMBRYO; ENDOPLASMIC RETICULUM ASSOCIATED DEGRADATION; ENZYME ACTIVITY; ENZYME MECHANISM; FIBROBLAST; GENE; GENE MUTATION; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN FOLDING; PROTEIN FUNCTION; PROTEIN STABILITY; ANIMAL; CELL CULTURE; ENDOPLASMIC RETICULUM; GENETICS; METABOLISM; MUTATION; RADIOIMMUNOPRECIPITATION;

MAMMALIA; MUS;

ACETYLGLUCOSAMINE; ANIMALS; CELLS, CULTURED; ENDOPLASMIC RETICULUM; MANNOSYL-GLYCOPROTEIN ENDO-BETA-N-ACETYLGLUCOSAMINIDASE; MICE; MUTATION; PEPTIDE-N4-(N-ACETYL-BETA-GLUCOSAMINYL) ASPARAGINE AMIDASE; RADIOIMMUNOPRECIPITATION ASSAY;

EID: 84922326714     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1414593112     Document Type: Article

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