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Journal of Molecular Catalysis B: Enzymatic

Volumn 113, Issue , 2015, Pages 76-81

Bioreductive production of enantiopure (S)-duloxetine intermediates catalyzed with ketoreductase ChKRED15

(5) Ren, Zhi Qiang a,b,c Liu, Yan a,b,c Pei, Xiao Qiong a,b,c Wang, Hai Bo a,b Wu, Zhong Liu a,b

a CHENGDU INSTITUTE OF BIOLOGY (China)

b Environmental Microbiology Key Laboratory of Sichuan Province (China)

c UNIVERSITY OF CHINESE ACADEMY OF SCIENCES (China)

Author keywords

Bioreduction; Chiral alcohol; Duloxetine; Ketoreductase; Short chain dehydrogenase reductase

Indexed keywords

DEHYDROGENATION;

BIO REDUCTIONS; CHIRAL ALCOHOLS; DULOXETINE; KETOREDUCTASE; SHORT-CHAIN DEHYDROGENASE/REDUCTASE;

CATALYST ACTIVITY;

ALCOHOL DERIVATIVE; DULOXETINE; ETHYL 3 OXO 3 (THIOPHEN 2 YL)PROPANOATE; KETOREDUCTASE CHKRED15; N METHYL 3 OXO 3 (THIOPHEN 2 YL)PROPANAMIDE; OXIDOREDUCTASE; PROPIONAMIDE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; CATALYSIS; CHRYSEOBACTERIUM; CONCENTRATION (PARAMETERS); DRUG MANUFACTURE; DRUG STRUCTURE; ENANTIOSELECTIVITY; MUTATION; PROTEIN STABILITY; SEQUENCE ALIGNMENT;

EID: 84922311674 PISSN: 13811177 EISSN: 18733158 Source Type: Journal
DOI: 10.1016/j.molcatb.2015.01.008 Document Type: Article

Times cited : (21)

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