Chemo-enzymatic synthesis of the antidepressant duloxetine and its enantiomer

Chirality

Volumn 12, Issue 1, 2000, Pages 26-29

  Liu, Huiling ^a   Hoff, Bård Helge ^a   Anthonsen, Thorleif ^a  

^a NORWEGIAN UNIVERSITY OF SCIENCE AND TECHNOLOGY   (Norway)

Author keywords

Antidepressant; Duloxetine; Kinetic resolution; Lipase catalysis; Stereospecificity

Indexed keywords

ALCOHOL; BUTYRIC ACID; DULOXETINE; SODIUM BOROHYDRIDE; TRIACYLGLYCEROL LIPASE;

ARTICLE; DRUG STRUCTURE; DRUG SYNTHESIS; ENANTIOMER; ENZYME ACTIVITY; PRIORITY JOURNAL; RACEMIC MIXTURE;

ANTIDEPRESSIVE AGENTS; CANDIDA; KINETICS; LIPASE; SACCHAROMYCES CEREVISIAE; STEREOISOMERISM; THIOPHENES;

EID: 0033982110     PISSN: 08990042     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1520-636X(2000)12:1<26::AID-CHIR5>3.0.CO;2-Z     Document Type: Article

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