Loss of keratinocyte focal adhesion kinase stimulates dermal proteolysis through upregulation of MMP9 in wound healing

Annals of Surgery

Volumn 260, Issue 6, 2014, Pages 1138-1146

  Wong, Victor W ^a   Garg, Ravi K ^a   Sorkin, Michael ^a   Rustad, Kristine C ^a   Akaishi, Satoshi ^a   Levi, Kemal ^b   Nelson, Emily R ^a   Tran, Misha ^a   Rennert, Robert ^a   Liu, Wei ^a   Longaker, Michael T ^a   Dauskardt, Reinhold H ^b   Gurtner, Geoffrey C ^a  

^a STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b Stanford University   (United States)

Author keywords

Dermal remodeling; Focal adhesion kinase; Matrix metalloproteinase; Skin; Wound healing

Indexed keywords

CASPASE 3; COLLAGEN TYPE 1; COLLAGEN TYPE 2; FOCAL ADHESION KINASE; GELATINASE B; MITOGEN ACTIVATED PROTEIN KINASE P38; RNA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; CELL PROLIFERATION; CELL STIMULATION; CELL STRUCTURE; CELL SUSPENSION; CELL VIABILITY; CHRONIC WOUND; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME RELEASE; FEMALE; FLOW CYTOMETRY; GENE EXPRESSION; GENETIC TRANSFECTION; HISTOPATHOLOGY; HUMAN; HUMAN CELL; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; IN VITRO STUDY; IN VIVO STUDY; KERATINOCYTE; MECHANOTRANSDUCTION; MICROSCOPY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; TENSILE STRENGTH; TISSUE REPAIR; TRANSMISSION ELECTRON MICROSCOPY; UPREGULATION; WOUND HEALING; WOUND HEALING IMPAIRMENT; ZYMOGRAPHY; ANIMAL; BIOSYNTHESIS; CELL CULTURE; DISEASE MODEL; ENZYME LINKED IMMUNOSORBENT ASSAY; GENETICS; INJURY; KNOCKOUT MOUSE; METABOLISM; NEWBORN; PATHOLOGY; SKIN; ULTRASTRUCTURE;

ANIMALS; CELLS, CULTURED; DISEASE MODELS, ANIMAL; ENZYME-LINKED IMMUNOSORBENT ASSAY; FLOW CYTOMETRY; FOCAL ADHESION PROTEIN-TYROSINE KINASES; HUMANS; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; INFANT, NEWBORN; KERATINOCYTES; MICE; MICE, KNOCKOUT; MICROSCOPY, ELECTRON, TRANSMISSION; PROTEOLYSIS; RNA; SKIN; UP-REGULATION; WOUND HEALING; WOUNDS AND INJURIES;

EID: 84922311198     PISSN: 00034932     EISSN: 15281140     Source Type: Journal    
DOI: 10.1097/SLA.0000000000000219     Document Type: Article

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