Interleukin-1β increases permeability and upregulates the expression of vascular endothelial-cadherin in human renal glomerular endothelial cells

Molecular Medicine Reports

Volumn 11, Issue 5, 2015, Pages 3708-3714

  Du, Linna ^a   Dong, Fengyun ^a   Guo, Ling ^a   Hou, Yinglong ^a   Yi, Fan ^b   Liu, Ju ^a   Xu, Dongmei ^a  

^a SHANDONG UNIVERSITY   (China)

^b SHANDONG UNIVERSITY SCHOOL OF MEDICINE   (China)

Author keywords

Glomerular endothelial cells; Interleukin 1 ; Permeability; Vascular endothelial cadherin

Indexed keywords

CELL ADHESION MOLECULE; INTERLEUKIN 1BETA; VASCULAR ENDOTHELIAL CADHERIN; CADHERIN; LEUKOCYTE ANTIGEN;

ARTICLE; BLOOD VESSEL PERMEABILITY; ELECTRIC RESISTANCE; ENDOTHELIUM CELL; GENE EXPRESSION; GLOMERULUS CAPILLARY; HUMAN; HUMAN CELL; RENAL GLOMERULAR ENDOTHELIAL CELL; TRANSENDOTHELIAL ELECTRICAL RESISTANCE; UMBILICAL VEIN ENDOTHELIAL CELL; CAPILLARY PERMEABILITY; CYTOLOGY; DRUG EFFECTS; GENE EXPRESSION REGULATION; GENETICS; GLOMERULUS; METABOLISM;

ANTIGENS, CD; CADHERINS; CAPILLARY PERMEABILITY; ENDOTHELIAL CELLS; GENE EXPRESSION; GENE EXPRESSION REGULATION; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; HUMANS; INTERLEUKIN-1BETA; KIDNEY GLOMERULUS;

EID: 84922310936     PISSN: 17912997     EISSN: 17913004     Source Type: Journal    
DOI: 10.3892/mmr.2015.3172     Document Type: Article

References (41)

1. Miner JH: Glomerular basement membrane composition and the filtration barrier. Pediatr Nephrol 26: 1413-1417, 2011.
2. Levidiotis V and Power DA: New insights into the molecular biology of the glomerular filtration barrier and associated disease. Nephrology (Carlton) 10: 157-166, 2005.
3. Obeidat M and Ballermann BJ: Glomerular endothelium: a porous sieve and formidable barrier. Exp Cell Res 318: 964-972, 2012.
4. Haraldsson BS: The endothelium as part of the integrative glomerular barrier complex. Kidney Int 85: 8-11, 2014.
5. Haraldsson B, Nystrom J and Deen WM: Properties of the glomerular barrier and mechanisms of proteinuria. Physiol Rev 88: 451-487, 2008.
6. Savage CO: The biology of the glomerulus: endothelial cells. Kidney Int 45: 314-319, 1994.
7. Stylianou E and Saklatvala J: Interleukin-1. Int J Biochem Cell Biol 30: 1075-1079, 1998.
8. Al-Sadi R, Boivin M and Ma T: Mechanism of cytokine modulation of epithelial tight junction barrier. Front Biosci (Landmark Ed) 14: 2765-2778, 2009.
9. Yamanaka N and Shimizu A: Role of glomerular endothelial damage in progressive renal disease. Kidney Blood Press Res 22: 13-20, 1999.
10. Lee LK, Meyer TW, Pollock AS and Lovett DH: Endothelial cell injury initiates glomerular sclerosis in the rat remnant kidney. J Clin Invest 96: 953-964, 1995.
11. van de Veerdonk FL and Netea MG: New Insights in the Immunobiology of IL-1 Family Members. Front Immunol 4: 167, 2013.
12. Zhao R, Zhou H and Su SB: A critical role for interleukin-1beta in the progression of autoimmune diseases. Int Immunopharmacol 17: 658-669, 2013.
13. Himmelfarb J, Le P, Klenzak J, Freedman S, McMenamin ME and Ikizler TA: Impaired monocyte cytokine production in critically ill patients with acute renal failure. Kidney Int 66: 2354-2360, 2004.
14. Boraschi D, Bossu P, Macchia G, Ruggiero P and Tagliabue A: Structure-function relationship in the IL-1 family. Front Biosci 1: d270-d308, 1996.
15. Auron PE: The interleukin 1 receptor: ligand interactions and signal transduction. Cytokine Growth Factor Rev 9: 221-237, 1998.
16. Dinarello CA: The IL-1 family and inflammatory diseases. Clin Exp Rheumatol 20: S1-S13, 2002.
17. Voronov E, Carmi Y and Apte RN: Role of IL-1-mediated inflammation in tumor angiogenesis. Adv Exp Med Biol 601: 265-270, 2007.
18. Wong D, Dorovini-Zis K and Vincent SR: Cytokines, nitric oxide and cGMP modulate the permeability of an in vitro model of the human blood-brain barrier. Exp Neurol 190: 446-455, 2004.
19. Nooteboom A, Van Der Linden CJ and Hendriks T: Tumor necrosis factor-alpha and interleukin-1beta mediate endothelial permeability induced by lipopolysaccharide-stimulated whole blood. Crit Care Med 30: 2063-2068, 2002.
20. Ganter MT, Roux J, Miyazawa B, et al: Interleukin-1beta causes acute lung injury via alphavbeta5 and alphavbeta6 integrin-dependent mechanisms. Circ Res 102: 804-812, 2008.
21. Du P, Fan B, Han H, et al: NOD2 promotes renal injury by exacerbating inflammation and podocyte insulin resistance in diabetic nephropathy. Kidney Int 84: 265-276, 2013.
22. Liu J, Yuan L, Molema G, et al: Vascular bed-specific regulation of the von Willebrand factor promoter in the heart and skeletal muscle. Blood 117: 342-351, 2011.
23. Becker PM, Verin AD, Booth MA, Liu F, Birukova A and Garcia JG: Differential regulation of diverse physiological responses to VEGF in pulmonary endothelial cells. Am J Physiol 281: L1500-L1511, 2001.
24. Birukova AA, Birukov KG, Smurova K, et al: Novel role of microtubules in thrombin-induced endothelial barrier dysfunction. FASEB J 18: 1879-1890, 2004.
25. Hordijk PL, Anthony E, Mul FP, Rientsma R, Oomen LC and Roos D: Vascular-endothelial-cadherin modulates endothelial monolayer permeability. J Cell Sci 112 (Pt 12): 1915-1923, 1999.
26. Ponnuchamy B and Khalil RA: Cellular mediators of renal vascular dysfunction in hypertension. Am J Physiol Regul Integr Comp Physiol 296: R1001-R1018, 2009.
27. Dejana E and Giampietro C: Vascular endothelial-cadherin and vascular stability. Curr Opinion Hematol 19: 218-223, 2012.
28. Deen WM: What determines glomerular capillary permeability? J Clin Invest 114: 1412-1414, 2004.
29. Obeidat M, Obeidat M and Ballermann BJ: Glomerular endothelium: a porous sieve and formidable barrier. Exp Cell Res 318: 964-972, 2012.
30. Vestweber D: VE-cadherin: the major endothelial adhesion molecule controlling cellular junctions and blood vessel formation. Arterioscler Thromb Vasc Biol 28: 223-232, 2008.
31. Burke-Gaffney A and Keenan AK: Modulation of human endothelial cell permeability by combinations of the cytokines interleukin-1 alpha/beta, tumor necrosis factor-alpha and interferon-gamma. Immunopharmacology 25: 1-9, 1993.
32. Cromer WE, Zawieja SD, Tharakan B, Childs EW, Newell MK and Zawieja DC: The effects of inflammatory cytokines on lymphatic endothelial barrier function. Angiogenesi 2013.
33. Qin W, Lu W, Li H, et al: Melatonin inhibits IL1beta-induced MMP9 expression and activity in human umbilical vein endothelial cells by suppressing NF-kappaB activation. J Endocrinol 214: 145-153, 2012.
34. Rigor RR, Beard RS, Jr, Litovka OP and Yuan SY: Interleukin-1beta-induced barrier dysfunction is signaled through PKC-theta in human brain microvascular endothelium. Am J Physiol. Cell Physiol 302: C1513-C1522, 2012.
35. Duffy HS, John GR, Lee SC, Brosnan CF and Spray DC: Reciprocal regulation of the junctional proteins claudin-1 and connexin43 by interleukin-1beta in primary human fetal astrocytes. J Neurosci 20: RC114, 2000.
36. Qi J, Chi L, Bynum D and Banes AJ: Gap junctions in IL-1beta-mediated cell survival response to strain. J Appl Physiol 110: 1425-1431, 2011.
37. Kinjo T, Takashi M, Miyake K and Nagura H: Phenotypic heterogeneity of vascular endothelial cells in the human kidney. Cell Tissue Res 256: 27-34, 1989.
38. Atkins GB, Jain MK and Hamik A: Endothelial differentiation: molecular mechanisms of specification and heterogeneity. Arterioscler Thromb Vasc Biol 31: 1476-1484, 2011.
39. Aird WC: Mechanisms of endothelial cell heterogeneity in health and disease. Circ Res 98: 159-162, 2006.
40. Deng DX, Tsalenko A, Vailaya A, et al: Differences in vascular bed disease susceptibility reflect differences in gene expression response to atherogenic stimuli. Cir Res 98: 200-208, 2006.
41. Molema G and Aird WC: Vascular heterogeneity in the kidney. Semin Nephrol 32: 145-155, 2012