Vascular Heterogeneity in the Kidney

Seminars in Nephrology

Volumn 32, Issue 2, 2012, Pages 145-155

  Molema, Grietje ^a,b   Aird, William C ^a  

^a BETH ISRAEL DEACONESS MEDICAL CENTER   (United States)

^b UNIVERSITY MEDICAL CENTER GRONINGEN   (Netherlands)

Author keywords

Endothelial cells; Heterogeneity; Kidney; Vasculature

Indexed keywords

ANATOMICAL CONCEPTS; ARTERIOLE; ARTERY ENDOTHELIUM; ARTICLE; BLOOD VESSEL FUNCTION; CLINICAL FEATURE; DISEASE ASSOCIATION; FLOW RATE; GLOMERULAR FILTRATION BARRIER; GLOMERULUS BASEMENT MEMBRANE; GLOMERULUS CAPILLARY; HUMAN; KIDNEY BLOOD VESSEL; KIDNEY CIRCULATION; KIDNEY CORTEX; KIDNEY DISEASE; KIDNEY FUNCTION; KIDNEY MEDULLA; KIDNEY TUBULE; KIDNEY VEIN; MACROVESSEL; MOLECULAR PATHOLOGY; NONHUMAN; PERIPHERAL VASCULAR SYSTEM; PHENOTYPE; PRIORITY JOURNAL; PUBLICATION; REGULATORY MECHANISM; RENAL ARTERY; SYNDROME DELINEATION; SYSTEMIC CIRCULATION; VASA RECTA; VASA VASORUM; VENULE;

ANIMALS; ARTERIOLES; CAPILLARIES; ENDOTHELIAL CELLS; HUMANS; KIDNEY; KIDNEY GLOMERULUS; RENAL ARTERY; RENAL VEINS;

EID: 84862088780     PISSN: 02709295     EISSN: 15584488     Source Type: Journal    
DOI: 10.1016/j.semnephrol.2012.02.001     Document Type: Article

References (82)

1. Aird W.C. Phenotypic heterogeneity of the endothelium: I. Structure, function, and mechanisms. Circ Res 2007, 100:158-173.
2. Aird W.C. Phenotypic heterogeneity of the endothelium: II. Representative vascular beds. Circ Res 2007, 100:174-190.
3. Evans R.G., Gardiner B.S., Smith D.W., O'Connor P.M. Intrarenal oxygenation: unique challenges and the biophysical basis of homeostasis. Am J Physiol Renal Physiol 2008, 295:F1259-F1270.
4. Evans R.G., Eppel G.A., Anderson W.P., Denton K.M. Mechanisms underlying the differential control of blood flow in the renal medulla and cortex. J Hypertens 2004, 22:1439-1451.
5. Eppel G.A., Malpas S.C., Denton K.M., Evans R.G. Neural control of renal medullary perfusion. Clin Exp Pharmacol Physiol 2004, 31:387-396.
6. Urban B.A., Ratner L.E., Fishman E.K. Three-dimensional volume-rendered CT angiography of the renal arteries and veins: normal anatomy, variants, and clinical applications. Radiographics 2001, 21:373-386. questionnaire, 549-55.
7. Sakai T., Kobayashi N. Structural relationships between the endothelial actin system and the underlying elastic layer in the distal interlobular artery of the rat kidney. Anat Embryol (Berl) 1992, 186:467-476.
8. Galili O., Herrmann J., Woodrum J., Sattler K.J., Lerman L.O., Lerman A. Adventitial vasa vasorum heterogeneity among different vascular beds. J Vasc Surg 2004, 40:529-535.
9. Hildebrandt H.A., Gossl M., Mannheim D., et al. Differential distribution of vasa vasorum in different vascular beds in humans. Atherosclerosis 2008, 199:47-54.
10. Frank M., Kriz W. The luminal aspect of intrarenal arteries and veins in the rat as revealed by scanning electron microscopy. Anat Embryol (Berl) 1988, 177:371-376.
11. Levin A., Linas S., Luft F.C., Chapman A.B., Textor S. Controversies in renal artery stenosis: a review by the American Society of Nephrology Advisory Group on Hypertension. Am J Nephrol 2007, 27:212-220.
12. Krumme B., Donauer J. Atherosclerotic renal artery stenosis and reconstruction. Kidney Int 2006, 70:1543-1547.
13. Bell T.D., Welch W.J. Regulation of renal arteriolar tone by adenosine: novel role for type 2 receptors. Kidney Int 2009, 75:769-771.
14. Al-Mashhadi R.H., Skott O., Vanhoutte P.M., Hansen P.B. Activation of A(2) adenosine receptors dilates cortical efferent arterioles in mouse. Kidney Int 2009, 75:793-799.
15. Loutzenhiser K., Loutzenhiser R. Angiotensin II-induced Ca(2+) influx in renal afferent and efferent arterioles: differing roles of voltage-gated and store-operated Ca(2+) entry. Circ Res 2000, 87:551-557.
16. Rosivall L., Peti-Peterdi J. Heterogeneity of the afferent arteriole-correlations between morphology and function. Nephrol Dial Transplant 2006, 21:2703-2707.
17. Skov P.V., Bennett M.B. Structural basis for control of secondary vessels in the long-finned eel Anguilla reinhardtii. J Exp Biol 2004, 207:3339-3348.
18. Deen W.M. What determines glomerular capillary permeability?. J Clin Invest 2004, 114:1412-1414.
19. Quaggin S.E., Kreidberg J.A. Development of the renal glomerulus: good neighbors and good fences. Development 2008, 135:609-620.
20. Salmon A.H., Neal C.R., Harper S.J. New aspects of glomerular filtration barrier structure and function: five layers (at least) not three. Curr Opin Nephrol Hypertens 2009, 18:197-205.
21. Izzedine H., Massard C., Spano J.P., Goldwasser F., Khayat D., Soria J.C. VEGF signalling inhibition-induced proteinuria: mechanisms, significance and management. Eur J Cancer 2010, 46:439-448.
22. Haraldsson B., Nystrom J., Deen W.M. Properties of the glomerular barrier and mechanisms of proteinuria. Physiol Rev 2008, 88:451-487.
23. Ballermann B.J. Glomerular endothelial cell differentiation. Kidney Int 2005, 67:1668-1671.
24. Satchell S.C., Braet F. Glomerular endothelial cell fenestrations: an integral component of the glomerular filtration barrier. Am J Physiol Renal Physiol 2009, 296:F947-F956.
25. Haraldsson B., Jeansson M. Glomerular filtration barrier. Curr Opin Nephrol Hypertens 2009, 18:331-335.
26. Ballermann B.J. Contribution of the endothelium to the glomerular permselectivity barrier in health and disease. Nephron Physiol 2007, 106:19-25.
27. Ballermann B.J., Stan R.V. Resolved: capillary endothelium is a major contributor to the glomerular filtration barrier. J Am Soc Nephrol 2007, 18:2432-2438.
28. Navar L.G. Glomerular permeability: a never-ending saga. Am J Physiol Renal Physiol 2009, 296:F1266-F1268.
29. Vaughan M.R., Quaggin S.E. How do mesangial and endothelial cells form the glomerular tuft?. J Am Soc Nephrol 2008, 19:24-33.
30. Jarad G., Miner J.H. Update on the glomerular filtration barrier. Curr Opin Nephrol Hypertens 2009, 18:226-232.
31. Bulger R.E., Eknoyan G., Purcell D.J., Dobyan D.C. Endothelial characteristics of glomerular capillaries in normal, mercuric chloride-induced, and gentamicin-induced acute renal failure in the rat. J Clin Invest 1983, 72:128-141.
32. Stan R.V., Kubitza M., Palade G.E. PV-1 is a component of the fenestral and stomatal diaphragms in fenestrated endothelia. Proc Natl Acad Sci U S A 1999, 96:13203-13207.
33. Ichimura K., Stan R.V., Kurihara H., Sakai T. Glomerular endothelial cells form diaphragms during development and pathologic conditions. J Am Soc Nephrol 2008, 19:1463-1471.
34. Eremina V., Jefferson J.A., Kowalewska J., et al. VEGF inhibition and renal thrombotic microangiopathy. N Engl J Med 2008, 358:1129-1136.
35. Eremina V., Sood M., Haigh J., et al. Glomerular-specific alterations of VEGF-A expression lead to distinct congenital and acquired renal diseases. J Clin Invest 2003, 111:707-716.
36. Avasthi P.S., Koshy V. The anionic matrix at the rat glomerular endothelial surface. Anat Rec 1988, 220:258-266.
37. Satchell S.C., Tooke J.E. What is the mechanism of microalbuminuria in diabetes: a role for the glomerular endothelium?. Diabetologia 2008, 51:714-725.
38. Aird W.C. Spatial and temporal dynamics of the endothelium. J Thromb Haemost 2005, 3:1392-1406.
39. Sengoelge G., Luo W., Fine D., et al. A SAGE-based comparison between glomerular and aortic endothelial cells. Am J Physiol Renal Physiol 2005, 288:F1290-F1300.
40. Takemoto M., He L., Norlin J., et al. Large-scale identification of genes implicated in kidney glomerulus development and function. EMBO J 2006, 25:1160-1174.
41. Betsholtz C., He L., Takemoto M., et al. The glomerular transcriptome and proteome. Nephron Exp Nephrol 2007, 106:e32-e36.
42. Shankland S.J. The podocyte's response to injury: role in proteinuria and glomerulosclerosis. Kidney Int 2006, 69:2131-2147.
43. Hohenstein B., Hausknecht B., Boehmer K., Riess R., Brekken R.A., Hugo C.P. Local VEGF activity but not VEGF expression is tightly regulated during diabetic nephropathy in man. Kidney Int 2006, 69:1654-1661.
44. Nakagawa T., Kosugi T., Haneda M., Rivard C.J., Long D.A. Abnormal angiogenesis in diabetic nephropathy. Diabetes 2009, 58:1471-1478.
45. Jensen J.S., Feldt-Rasmussen B., Strandgaard S., Schroll M., Borch-Johnsen K. Arterial hypertension, microalbuminuria, and risk of ischemic heart disease. Hypertension 2000, 35:898-903.
46. Schlondorff D.O. Overview of factors contributing to the pathophysiology of progressive renal disease. Kidney Int 2008, 74:860-866.
47. Hara A., Wada T., Furuichi K., et al. Blockade of VEGF accelerates proteinuria, via decrease in nephrin expression in rat crescentic glomerulonephritis. Kidney Int 2006, 69:1986-1995.
48. Mutter W.P., Karumanchi S.A. Molecular mechanisms of preeclampsia. Microvasc Res 2008, 75:1-8.
49. Khan F., Proulx F., Lingwood C.A. Detergent-resistant globotriaosyl ceramide may define verotoxin/glomeruli-restricted hemolytic uremic syndrome pathology. Kidney Int 2009, 75:1209-1216.
50. Lingwood C.A. Verotoxin-binding in human renal sections. Nephron 1994, 66:21-28.
51. Franssen C.F., Stegeman C.A., Kallenberg C.G., et al. Antiproteinase 3- and antimyeloperoxidase-associated vasculitis. Kidney Int 2000, 57:2195-2206.
52. van der Veen B.S., de Winther M.P., Heeringa P. Myeloperoxidase: molecular mechanisms of action and their relevance to human health and disease. Antioxid Redox Signal 2009, 11:2899-2937.
53. Van Timmeren M.M., Chen M., Heeringa P. Review article: pathogenic role of complement activation in anti-neutrophil cytoplasmic auto-antibody-associated vasculitis. Nephrology (Carlton) 2009, 14:16-25.
54. Beeuwkes R. The vascular organization of the kidney. Annu Rev Physiol 1980, 42:531-542.
55. Aydin S., Signorelli S., Lechleitner T., et al. Influence of microvascular endothelial cells on transcriptional regulation of proximal tubular epithelial cells. Am J Physiol Cell Physiol 2008, 294:C543-C554.
56. van Poelgeest E.P., Baelde H.J., Lagaaij E.L., et al. Endothelial cell chimerism occurs more often and earlier in female than in male recipients of kidney transplants. Kidney Int 2005, 68:847-853.
57. Li J., Deane J.A., Campanale N.V., Bertram J.F., Ricardo S.D. Blockade of p38 mitogen-activated protein kinase and TGF-beta1/Smad signaling pathways rescues bone marrow-derived peritubular capillary endothelial cells in adriamycin-induced nephrosis. J Am Soc Nephrol 2006, 17:2799-2811.
58. Evan A.P., Hay D.A. Ultrastructure of the developing vascular system in the puppy kidney. Anat Rec 1981, 199:481-489.
59. Ivanyi B., Hansen H.E., Olsen T.S. Postcapillary venule-like transformation of peritubular capillaries in acute renal allograft rejection. An ultrastructural study. Arch Pathol Lab Med 1992, 116:1062-1067.
60. Monga G., Mazzucco G., Novara R., Reale L. Intertubular capillary changes in kidney allografts: an ultrastructural study in patients with transplant glomerulopathy. Ultrastruct Pathol 1990, 14:201-209.
61. Ivanyi B., Fahmy H., Brown H., Szenohradszky P., Halloran P.F., Solez K. Peritubular capillaries in chronic renal allograft rejection: a quantitative ultrastructural study. Hum Pathol 2000, 31:1129-1138.
62. Kwon O., Hong S.M., Sutton T.A., Temm C.J. Preservation of peritubular capillary endothelial integrity and increasing pericytes may be critical to recovery from postischemic acute kidney injury. Am J Physiol Renal Physiol 2008, 295:F351-F359.
63. Panzer U., Steinmetz O.M., Reinking R.R., et al. Compartment-specific expression and function of the chemokine IP-10/CXCL10 in a model of renal endothelial microvascular injury. J Am Soc Nephrol 2006, 17:454-464.
64. Pallone T.L., Zhang Z., Rhinehart K. Physiology of the renal medullary microcirculation. Am J Physiol Renal Physiol 2003, 284:F253-F266.
65. Pannabecker T.L., Dantzler W.H. Three-dimensional architecture of inner medullary vasa recta. Am J Physiol Renal Physiol 2006, 290:F1355-F1366.
66. Zhang W., Edwards A. A model of nitric oxide tubulovascular cross talk in a renal outer medullary cross section. Am J Physiol Renal Physiol 2007, 292:F711-F722.
67. MacPhee P.J. Fluid uptake by the renal medullary vasa recta: an estimate based on a quantitative analysis of the distribution of fenestrae in the vasa recta of young Sprague-Dawley rats. Exp Physiol 1998, 83:23-34.
68. Zhang W., Edwards A. Oxygen transport across vasa recta in the renal medulla. Am J Physiol Heart Circ Physiol 2002, 283:H1042-H1055.
69. Fenton R.A., Knepper M.A. Urea and renal function in the 21st century: insights from knockout mice. J Am Soc Nephrol 2007, 18:679-688.
70. Verkman A.S. Aquaporins in endothelia. Kidney Int 2006, 69:1120-1123.
71. Zhang Q., Cao C., Mangano M., et al. Descending vasa recta endothelium is an electrical syncytium. Am J Physiol Regul Integr Comp Physiol 2006, 291:R1688-R1699.
72. Schwartz M.M., Karnovsky M.J., Vehkatachalam M.A. Ultrastructural differences between rat inner medullary descending and ascending vasa recta. Lab Invest 1976, 35:161-170.
73. Pannabecker T.L., Dantzler W.H. Three-dimensional architecture of collecting ducts, loops of Henle, and blood vessels in the renal papilla. Am J Physiol Renal Physiol 2007, 293:F696-F704.
74. Zimmerhackl B., Robertson C.R., Jamison R.L. Fluid uptake in the renal papilla by vasa recta estimated by two methods simultaneously. Am J Physiol 1985, 248:F347-F353.
75. Beckmann C.F., Abrams H.L. Renal venography: anatomy, technique, applications, analysis of 132 venograms, and a review of the literature. Cardiovasc Intervent Radiol 1980, 3:45-70.
76. Espinoza-Valdez A., Femat R., Ordaz-Salazar F.C. A model for renal arterial branching based on graph theory. Math Biosci 2010, 225:36-43.
77. Baptista-Silva J.C., Verissimo M.J., Castro M.J., Camara A.L., Pestana J.O. Anatomical study of the renal veins observed during 342 living-donor nephrectomies. Sao Paulo Med J 1997, 115:1456-1459.
78. Beckmann C.F., Abrams H.L. Renal vein valves: incidence and significance. Radiology 1978, 127:351-356.
79. Jones W.R., O'Morchoe C.C. Ultrastructural evidence for a reabsorptive role by intrarenal veins. Anat Rec 1983, 207:253-262.
80. Vodenicharov A. Endothelin-positive mast cells in porcine renal artery and vein. Anat Histol Embryol 2008, 37:376-379.
81. Dimitroulis D., Bokos J., Zavos G., et al. Vascular complications in renal transplantation: a single-center experience in 1367 renal transplantations and review of the literature. Transplant Proc 2009, 41:1609-1614.
82. Torbenson M., Randhawa P. Arcuate and interlobular phlebitis in renal allografts. Hum Pathol 2001, 32:1388-1391.