A dimer interface mutation in glyceraldehyde-3-phosphate dehydrogenase regulates its binding to AU-rich RNA

Journal of Biological Chemistry

Volumn 290, Issue 3, 2015, Pages 1770-1785

  White, Michael R ^a   Khan, Mohd M ^a,b   Deredge, Daniel ^b   Ross, Christina R ^c   Quintyn, Royston ^d   Zucconi, Beth E ^c,e   Wysocki, Vicki H ^d   Wintrode, Patrick L ^b   Wilson, Gerald M ^c   Garcin, Elsa D ^a  

^a UNIVERSITY OF MARYLAND BALTIMORE COUNTY   (United States)

^b UNIVERSITY OF MARYLAND SCHOOL OF PHARMACY   (United States)

^c UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

^d OHIO STATE UNIVERSITY   (United States)

^e JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ELECTROSPRAY IONIZATION; MASS SPECTROMETRY; OLIGOMERS; RNA; SPECTROMETRY; X RAY CRYSTALLOGRAPHY; X RAY SCATTERING;

BINDING MECHANISMS; GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE; HYDROGEN-DEUTERIUM EXCHANGE; NANO-ELECTROSPRAY IONIZATIONS; NATIVE MASS SPECTROMETRIES; PROTEIN EXPRESSIONS; TUMOR NECROSIS FACTORS; UNTRANSLATED REGIONS;

NUCLEIC ACIDS;

GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; TETRAMER; TUMOR NECROSIS FACTOR ALPHA; 3' UNTRANSLATED REGION; COMPLEMENTARY DNA; PEPTIDE; PROTEIN BINDING; RNA; TUMOR NECROSIS FACTOR;

ARTICLE; AU RICH ELEMENT; BINDING AFFINITY; BINDING SITE; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; CRYSTALLOGRAPHY; MUTATION; NONHUMAN; OLIGOMERIZATION; PROTEIN RNA BINDING; RNA CONFORMATION; RNA STRUCTURE; WILD TYPE; X RAY CRYSTALLOGRAPHY; 3' UNTRANSLATED REGION; AMINO ACID SEQUENCE; ANISOTROPY; CHEMISTRY; ELECTROSPRAY MASS SPECTROMETRY; FLUORESCENCE MICROSCOPY; GENETICS; GLYCOLYSIS; HUMAN; METABOLISM; MOLECULAR GENETICS; PROTEIN CONFORMATION; PROTEIN MOTIF; PROTEIN MULTIMERIZATION; RADIATION SCATTERING; SEQUENCE HOMOLOGY; X RAY;

3' UNTRANSLATED REGIONS; AMINO ACID MOTIFS; AMINO ACID SEQUENCE; ANISOTROPY; BINDING SITES; DNA, COMPLEMENTARY; GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASES; GLYCOLYSIS; HUMANS; MICROSCOPY, FLUORESCENCE; MOLECULAR SEQUENCE DATA; MUTATION; PEPTIDES; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN MULTIMERIZATION; RNA; SCATTERING, RADIATION; SEQUENCE HOMOLOGY, AMINO ACID; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; TUMOR NECROSIS FACTOR-ALPHA; X-RAYS;

EID: 84922267757     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M114.618165     Document Type: Article

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