Alcohol directly stimulates epigenetic modifications in hepatic stellate cells

Journal of Hepatology

Volumn 62, Issue 2, 2015, Pages 388-397

  Page, Agata ^a   Paoli, Pier P ^a   Hill, Stephen J ^a   Howarth, Rachel ^a   Wu, Raymond ^b,c   Kweon, Soo Mi ^b,c   French, Jeremy ^a   White, Steve ^a   Tsukamoto, Hidekazu ^b,c   Mann, Derek A ^a   Mann, Jelena ^a  

^a NEWCASTLE UNIVERSITY   (United Kingdom)

^b UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^c VA GREATER LOS ANGELES HEALTHCARE SYSTEM   (United States)

Author keywords

ALD; Elastin; Epigenetics; H3K4me3; HSC; MLL1

Indexed keywords

ALCOHOL; ELASTIN; DNA; SCLEROPROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL ISOLATION; CELL STIMULATION; CELL TRANSDIFFERENTIATION; CHROMATIN IMMUNOPRECIPITATION; CHROMATIN STRUCTURE; CHRONIC LIVER DISEASE; CONTROLLED STUDY; DNA METHYLATION; DNA MODIFICATION; EPIGENETICS; EXTRACELLULAR MATRIX; GENE ACTIVATION; GENE EXPRESSION; GENE LOCUS; HISTONE MODIFICATION; HUMAN; HUMAN TISSUE; LIVER FIBROSIS; LIVER SLICE; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; STELLATE CELL; ALCOHOL LIVER CIRRHOSIS; ANIMAL; BIOSYNTHESIS; CELL CULTURE; DISEASE COURSE; DISEASE MODEL; DRUG EFFECTS; GENE EXPRESSION REGULATION; GENETIC EPIGENESIS; GENETICS; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; METABOLISM; PATHOLOGY; POLYMERASE CHAIN REACTION; SPRAGUE DAWLEY RAT;

ANIMALS; CELL TRANSDIFFERENTIATION; CELLS, CULTURED; DISEASE MODELS, ANIMAL; DISEASE PROGRESSION; DNA; EPIGENESIS, GENETIC; ETHANOL; EXTRACELLULAR MATRIX PROTEINS; GENE EXPRESSION REGULATION; HEPATIC STELLATE CELLS; HUMANS; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; LIVER CIRRHOSIS, ALCOHOLIC; MALE; MICE; POLYMERASE CHAIN REACTION; RATS; RATS, SPRAGUE-DAWLEY;

EID: 84922244423     PISSN: 01688278     EISSN: 16000641     Source Type: Journal    
DOI: 10.1016/j.jhep.2014.09.033     Document Type: Article

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