Circulating TNF and mitochondrial DNA are major determinants of neutrophil phenotype in the advanced-age, frail elderly

Molecular Immunology

Volumn 65, Issue 1, 2015, Pages 148-156

  Verschoor, Chris P ^a   Loukov, Dessi ^a   Naidoo, Avee ^a   Puchta, Alicja ^a   Johnstone, Jennie ^a   Millar, Jamie ^a   Lelic, Alina ^a   Novakowski, Kyle E ^a   Dorrington, Michael G ^a   Loeb, Mark ^a   Bramson, Jonathan L ^a   Bowdish, Dawn M E ^a  

^a MCMASTER UNIVERSITY   (Canada)

Author keywords

Aging; CD11b; HLA DR; Mitochondrial DNA; Neutrophil; TNF

Indexed keywords

CD11B ANTIGEN; HLA DR ANTIGEN; MITOCHONDRIAL DNA; REACTIVE OXYGEN METABOLITE; TUMOR NECROSIS FACTOR; ITGAM PROTEIN, HUMAN; TLR9 PROTEIN, HUMAN; TNF PROTEIN, HUMAN; TOLL LIKE RECEPTOR 9; TUMOR NECROSIS FACTOR ALPHA;

ADULT; AGED; ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; CORRELATIONAL STUDY; DONOR; EX VIVO STUDY; FEMALE; FRAIL ELDERLY; HUMAN; IN VIVO STUDY; MALE; MOUSE; NEUTROPHIL; NONHUMAN; NORMAL HUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; ANIMAL; BIOSYNTHESIS; BLOOD; C57BL MOUSE; CHRONIC DISEASE; GENETICS; IMMUNOLOGY; INFLAMMATION; KNOCKOUT MOUSE; LEUKOCYTE ACTIVATION; LEUKOCYTE COUNT; METABOLISM; MIDDLE AGED; PHYSIOLOGY; VERY ELDERLY; YOUNG ADULT;

MUS;

ADULT; AGED; AGED, 80 AND OVER; ANIMALS; ANTIGENS, CD11B; CHRONIC DISEASE; DNA, MITOCHONDRIAL; FEMALE; FRAIL ELDERLY; HLA-DR ANTIGENS; HUMANS; INFLAMMATION; LEUKOCYTE COUNT; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MIDDLE AGED; NEUTROPHIL ACTIVATION; NEUTROPHILS; PHENOTYPE; REACTIVE OXYGEN SPECIES; TOLL-LIKE RECEPTOR 9; TUMOR NECROSIS FACTOR-ALPHA; YOUNG ADULT;

EID: 84922213705     PISSN: 01615890     EISSN: 18729142     Source Type: Journal    
DOI: 10.1016/j.molimm.2015.01.015     Document Type: Article

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