Molecular basis of the dominant negative effect of a glycine transporter 2 mutation associated with hyperekplexia

Journal of Biological Chemistry

Volumn 290, Issue 4, 2015, Pages 2150-2165

  Arribas González, Esther ^a   De Juan Sanz, Jaime ^a,b,c   Aragón, Carmen ^a,b   López Corcuera, Beatriz ^a,b  

^a UNIVERSIDAD AUTÓNOMA DE MADRID   (Spain)

^b INSTITUTO DE SALUD CARLOS III   (Spain)

^c WEILL CORNELL MEDICAL COLLEGE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELL MEMBRANES; GENE ENCODING; NEURONS;

CHEMICAL CHAPERONE; CLINICAL SYNDROMES; DOMINANT-NEGATIVE MUTANTS; ENDOPLASMIC RETICULUM; HETEROLOGOUS CELLS; NEUROLOGICAL DISORDERS; STRUCTURAL ALTERATIONS; SURFACE EXPRESSION;

AMINO ACIDS;

ARGININE; CALNEXIN; CHAPERONE; COAT PROTEIN COMPLEX II; GLYCINE TRANSPORTER 2; SEC24D PROTEIN; SERINE; UNCLASSIFIED DRUG; GLYCINE; GLYCINE TRANSPORTER; SLC6A5 PROTEIN, HUMAN;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BRAIN CELL CULTURE; BRAIN CORTEX; CELL MEMBRANE; COS 7 CELL LINE; EMBRYO; ENDOPLASMIC RETICULUM; FETUS; GENE MUTATION; GENE STRUCTURE; GENETIC ASSOCIATION; GLYT2 GENE; HYPEREKPLEXIA; MDCK CELL LINE; NONHUMAN; OLIGOMERIZATION; PROTEIN EXPRESSION; PROTEIN FOLDING; PROTEIN PROTEIN INTERACTION; PROTEIN TRANSPORT; RAT; WILD TYPE; ANIMAL; BIOTINYLATION; CHEMISTRY; CHLOROCEBUS AETHIOPS; COS 1 CELL LINE; DENSITOMETRY; DOG; DOMINANT GENE; GENETICS; HUMAN; METABOLISM; MUTATION; NERVE CELL; STIFF MAN SYNDROME; SYNAPTIC TRANSMISSION; WISTAR RAT;

ANIMALS; BIOTINYLATION; CALNEXIN; CERCOPITHECUS AETHIOPS; CEREBRAL CORTEX; COS CELLS; DENSITOMETRY; DOGS; ENDOPLASMIC RETICULUM; GENES, DOMINANT; GLYCINE; GLYCINE PLASMA MEMBRANE TRANSPORT PROTEINS; HUMANS; MADIN DARBY CANINE KIDNEY CELLS; MOLECULAR CHAPERONES; MUTATION; NEURONS; RATS; RATS, WISTAR; STIFF-PERSON SYNDROME; SYNAPTIC TRANSMISSION;

EID: 84922182028     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M114.587055     Document Type: Article

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