메뉴 건너뛰기




Volumn 28, Issue 12, 2014, Pages 1207-1213

Authors' reply to whitlock: Perispinal etanercept for post-stroke neurological and cognitive dysfunction: Scientific rationale and current evidence

Author keywords

[No Author keywords available]

Indexed keywords

CERTOLIZUMAB PEGOL; ESCITALOPRAM; ETANERCEPT; INFLIXIMAB; TUMOR NECROSIS FACTOR; IMMUNOGLOBULIN G; NEUROPROTECTIVE AGENT; TUMOR NECROSIS FACTOR RECEPTOR;

EID: 84922073814     PISSN: 11727047     EISSN: 11791934     Source Type: Journal    
DOI: 10.1007/s40263-014-0212-0     Document Type: Letter
Times cited : (6)

References (125)
  • 2
    • 0034677593 scopus 로고    scopus 로고
    • Brain-derived TNFalpha: Involvement in neuroplastic changes implicated in the conscious perception of persistent pain
    • 1:CAS:528:DC%2BD3cXhsleqsb8%3D 10720620
    • Covey WC, Ignatowski TA, Knight PR, Spengler RN. Brain-derived TNFalpha: involvement in neuroplastic changes implicated in the conscious perception of persistent pain. Brain Res. 2000;859(1):113-22.
    • (2000) Brain Res , vol.859 , Issue.1 , pp. 113-122
    • Covey, W.C.1    Ignatowski, T.A.2    Knight, P.R.3    Spengler, R.N.4
  • 3
    • 0036073658 scopus 로고    scopus 로고
    • Expression of neuron-associated tumor necrosis factor alpha in the brain is increased during persistent pain
    • 1:CAS:528:DC%2BD38XmsVGrsro%3D 12132059
    • Covey WC, Ignatowski TA, Renauld AE, Knight PR, Nader ND, Spengler RN. Expression of neuron-associated tumor necrosis factor alpha in the brain is increased during persistent pain. Reg Anesth Pain Med. 2002;27(4):357-66.
    • (2002) Reg Anesth Pain Med , vol.27 , Issue.4 , pp. 357-366
    • Covey, W.C.1    Ignatowski, T.A.2    Renauld, A.E.3    Knight, P.R.4    Nader, N.D.5    Spengler, R.N.6
  • 4
    • 16444374979 scopus 로고    scopus 로고
    • Effect of tumor necrosis factor-alpha on the reciprocal G-protein-induced regulation of norepinephrine release by the alpha2-adrenergic receptor
    • 1:CAS:528:DC%2BD2MXitFygsb4%3D 15672410
    • Reynolds JL, Ignatowski TA, Spengler RN. Effect of tumor necrosis factor-alpha on the reciprocal G-protein-induced regulation of norepinephrine release by the alpha2-adrenergic receptor. J Neurosci Res. 2005;79(6):779-87.
    • (2005) J Neurosci Res , vol.79 , Issue.6 , pp. 779-787
    • Reynolds, J.L.1    Ignatowski, T.A.2    Spengler, R.N.3
  • 6
    • 84864587707 scopus 로고    scopus 로고
    • Increasing TNF levels solely in the rat hippocampus produces persistent pain-like symptoms
    • 1:CAS:528:DC%2BC38XhtFKnurvO 3417838 22770843
    • Martuscello RT, Spengler RN, Bonoiu AC, Davidson BA, Helinski J, Ding H, et al. Increasing TNF levels solely in the rat hippocampus produces persistent pain-like symptoms. Pain. 2012;153(9):1871-82.
    • (2012) Pain , vol.153 , Issue.9 , pp. 1871-1882
    • Martuscello, R.T.1    Spengler, R.N.2    Bonoiu, A.C.3    Davidson, B.A.4    Helinski, J.5    Ding, H.6
  • 8
    • 33646201107 scopus 로고    scopus 로고
    • TNF-alpha modulation for treatment of Alzheimer's disease: A 6-month pilot study
    • Tobinick E, Gross H, Weinberger A, Cohen H. TNF-alpha modulation for treatment of Alzheimer's disease: a 6-month pilot study. Med Gen Med. 2006;8(2):25.
    • (2006) Med Gen Med , vol.8 , Issue.2 , pp. 25
    • Tobinick, E.1    Gross, H.2    Weinberger, A.3    Cohen, H.4
  • 9
    • 49949104408 scopus 로고    scopus 로고
    • Rapid improvement in verbal fluency and aphasia following perispinal etanercept in Alzheimer's disease
    • 2500042 18644112
    • Tobinick EL, Gross H. Rapid improvement in verbal fluency and aphasia following perispinal etanercept in Alzheimer's disease. BMC Neurol. 2008;8:27.
    • (2008) BMC Neurol , vol.8 , pp. 27
    • Tobinick, E.L.1    Gross, H.2
  • 10
    • 68949202019 scopus 로고    scopus 로고
    • Rapid intracerebroventricular delivery of Cu-DOTA-etanercept after peripheral administration demonstrated by PET imaging
    • 2651903 19284700
    • Tobinick EL, Chen K, Chen X. Rapid intracerebroventricular delivery of Cu-DOTA-etanercept after peripheral administration demonstrated by PET imaging. BMC Res Notes. 2009;2:28.
    • (2009) BMC Res Notes , vol.2 , pp. 28
    • Tobinick, E.L.1    Chen, K.2    Chen, X.3
  • 11
    • 0038352253 scopus 로고    scopus 로고
    • Perispinal TNF-alpha inhibition for discogenic pain
    • 1:CAS:528:DC%2BD3sXkslCqtrY%3D 12715286
    • Tobinick EL, Britschgi-Davoodifar S. Perispinal TNF-alpha inhibition for discogenic pain. Swiss Med Wkly. 2003;133(11-12):170-7.
    • (2003) Swiss Med Wkly , vol.133 , Issue.11-12 , pp. 170-177
    • Tobinick, E.L.1    Britschgi-Davoodifar, S.2
  • 12
    • 3242699018 scopus 로고    scopus 로고
    • Efficacy of etanercept delivered by perispinal administration for chronic back and/or neck disc-related pain: A study of clinical observations in 143 patients
    • 1:CAS:528:DC%2BD2cXmvVyktLY%3D 15265252
    • Tobinick E, Davoodifar S. Efficacy of etanercept delivered by perispinal administration for chronic back and/or neck disc-related pain: a study of clinical observations in 143 patients. Curr Med Res Opin. 2004;20(7):1075-85.
    • (2004) Curr Med Res Opin , vol.20 , Issue.7 , pp. 1075-1085
    • Tobinick, E.1    Davoodifar, S.2
  • 13
    • 37049002092 scopus 로고    scopus 로고
    • Perispinal etanercept for treatment of Alzheimer's disease
    • 1:CAS:528:DC%2BD1cXisVGqtg%3D%3D 18220520
    • Tobinick E. Perispinal etanercept for treatment of Alzheimer's disease. Curr Alzheimer Res. 2007;4(5):550-2.
    • (2007) Curr Alzheimer Res , vol.4 , Issue.5 , pp. 550-552
    • Tobinick, E.1
  • 14
    • 39349087157 scopus 로고    scopus 로고
    • Perispinal etanercept: Potential as an Alzheimer therapeutic
    • Griffin WS. Perispinal etanercept: potential as an Alzheimer therapeutic. J Neuroinflamm. 2008;5:3.
    • (2008) J Neuroinflamm , vol.5 , pp. 3
    • Griffin, W.S.1
  • 15
    • 84856453919 scopus 로고    scopus 로고
    • Progressive and unconventional pharmacotherapeutic approaches to Alzheimer's disease therapy
    • 1:CAS:528:DC%2BC38Xjt1Chsrg%3D 22329648
    • Maudsley S, Chadwick W. Progressive and unconventional pharmacotherapeutic approaches to Alzheimer's disease therapy. Curr Alzheimer Res. 2012;9(1):1-4.
    • (2012) Curr Alzheimer Res , vol.9 , Issue.1 , pp. 1-4
    • Maudsley, S.1    Chadwick, W.2
  • 16
    • 84856459784 scopus 로고    scopus 로고
    • Deciphering the physiology underlying the rapid clinical effects of perispinal etanercept in Alzheimer's disease
    • 1:CAS:528:DC%2BC38Xjt1Chs7g%3D 22191562
    • Tobinick E. Deciphering the physiology underlying the rapid clinical effects of perispinal etanercept in Alzheimer's disease. Curr Alzheimer Res. 2012;9(1):99-109.
    • (2012) Curr Alzheimer Res , vol.9 , Issue.1 , pp. 99-109
    • Tobinick, E.1
  • 17
    • 84904963126 scopus 로고    scopus 로고
    • Perispinal etanercept for post-stroke neurological and cognitive dysfunction: Scientific rationale and current evidence
    • 1:CAS:528:DC%2BC2cXptVCntLg%3D 4110406 24861337
    • Ignatowski TA, Spengler RN, Dhandapani KM, Folkersma H, Butterworth RF, Tobinick E. Perispinal etanercept for post-stroke neurological and cognitive dysfunction: scientific rationale and current evidence. CNS Drugs. 2014;28(8):679-97.
    • (2014) CNS Drugs , vol.28 , Issue.8 , pp. 679-697
    • Ignatowski, T.A.1    Spengler, R.N.2    Dhandapani, K.M.3    Folkersma, H.4    Butterworth, R.F.5    Tobinick, E.6
  • 18
    • 84887558761 scopus 로고    scopus 로고
    • INMiND: Getting to the bottom of neuroinflammation
    • 24229613
    • Mohammadi D. INMiND: getting to the bottom of neuroinflammation. Lancet Neurol. 2013;12(12):1135-6.
    • (2013) Lancet Neurol , vol.12 , Issue.12 , pp. 1135-1136
    • Mohammadi, D.1
  • 20
    • 84904538940 scopus 로고    scopus 로고
    • Call for papers: Neurology: Neuroimmunology and Neuroinflammation, a new neurology journal
    • Ransohoff R. Call for papers: Neurology: Neuroimmunology and Neuroinflammation, a new neurology journal. Neurology. 2014;82:648-9.
    • (2014) Neurology , vol.82 , pp. 648-649
    • Ransohoff, R.1
  • 21
    • 84922400795 scopus 로고    scopus 로고
    • Effects of centrally administered etanercept on behaviour, microglia and astrocytes in mice following a peripheral immune challenge
    • Camara ML, Corrigan F, Jaehne EJ, Jawahar MC, Anscomb H, Baune BT. Effects of centrally administered etanercept on behaviour, microglia and astrocytes in mice following a peripheral immune challenge. Neuropsychopharmacology. 2014;. doi: 10.1038/npp.2014.199.
    • (2014) Neuropsychopharmacology
    • Camara, M.L.1    Corrigan, F.2    Jaehne, E.J.3    Jawahar, M.C.4    Anscomb, H.5    Baune, B.T.6
  • 22
    • 79952748060 scopus 로고    scopus 로고
    • Blockade of TNF-alpha rapidly inhibits pain responses in the central nervous system
    • 1:CAS:528:DC%2BC3MXivFOnt74%3D 3048151 21245297
    • Hess A, Axmann R, Rech J, Finzel S, Heindl C, Kreitz S, et al. Blockade of TNF-alpha rapidly inhibits pain responses in the central nervous system. Proc Natl Acad Sci USA. 2011;108(9):3731-6.
    • (2011) Proc Natl Acad Sci USA , vol.108 , Issue.9 , pp. 3731-3736
    • Hess, A.1    Axmann, R.2    Rech, J.3    Finzel, S.4    Heindl, C.5    Kreitz, S.6
  • 24
    • 77953192854 scopus 로고    scopus 로고
    • Perispinal etanercept: A new therapeutic paradigm in neurology
    • 1:CAS:528:DC%2BC3cXmvVWktrk%3D 20518613
    • Tobinick E. Perispinal etanercept: a new therapeutic paradigm in neurology. Expert Rev Neurother. 2010;10(6):985-1002.
    • (2010) Expert Rev Neurother , vol.10 , Issue.6 , pp. 985-1002
    • Tobinick, E.1
  • 25
    • 78951493751 scopus 로고    scopus 로고
    • Rapid improvement of chronic stroke deficits after perispinal etanercept: Three consecutive cases
    • 1:CAS:528:DC%2BC3MXjsFOjt70%3D 21254790
    • Tobinick E. Rapid improvement of chronic stroke deficits after perispinal etanercept: three consecutive cases. CNS Drugs. 2011;25(2):145-55.
    • (2011) CNS Drugs , vol.25 , Issue.2 , pp. 145-155
    • Tobinick, E.1
  • 26
    • 84873416770 scopus 로고    scopus 로고
    • Selective TNF inhibition for chronic stroke and traumatic brain injury: An observational study involving 629 consecutive patients treated with perispinal etanercept
    • 1:CAS:528:DC%2BC3sXhsVagu74%3D 23100196
    • Tobinick E, Kim NM, Reyzin G, Rodriguez-Romanacce H, Depuy V. Selective TNF inhibition for chronic stroke and traumatic brain injury: an observational study involving 629 consecutive patients treated with perispinal etanercept. CNS Drugs. 2012;26(12):1051-70.
    • (2012) CNS Drugs , vol.26 , Issue.12 , pp. 1051-1070
    • Tobinick, E.1    Kim, N.M.2    Reyzin, G.3    Rodriguez-Romanacce, H.4    Depuy, V.5
  • 27
    • 38549178015 scopus 로고    scopus 로고
    • Rapid cognitive improvement in Alzheimer's disease following perispinal etanercept administration
    • Tobinick EL, Gross H. Rapid cognitive improvement in Alzheimer's disease following perispinal etanercept administration. J Neuroinflamm. 2008;5:2.
    • (2008) J Neuroinflamm , vol.5 , pp. 2
    • Tobinick, E.L.1    Gross, H.2
  • 28
    • 84873818745 scopus 로고    scopus 로고
    • Association of brain functional magnetic resonance activity with response to tumor necrosis factor inhibition in rheumatoid arthritis
    • 1:CAS:528:DC%2BC3sXhsFCju74%3D 23238986
    • Rech J, Hess A, Finzel S, Kreitz S, Sergeeva M, Englbrecht M, et al. Association of brain functional magnetic resonance activity with response to tumor necrosis factor inhibition in rheumatoid arthritis. Arthritis Rheum. 2013;65(2):325-33.
    • (2013) Arthritis Rheum , vol.65 , Issue.2 , pp. 325-333
    • Rech, J.1    Hess, A.2    Finzel, S.3    Kreitz, S.4    Sergeeva, M.5    Englbrecht, M.6
  • 29
    • 0028172123 scopus 로고
    • Tumor necrosis factor-alpha: Presynaptic sensitivity is modified after antidepressant drug administration
    • 1:CAS:528:DyaK2MXitlWks74%3D 7895065
    • Ignatowski TA, Spengler RN. Tumor necrosis factor-alpha: presynaptic sensitivity is modified after antidepressant drug administration. Brain Res. 1994;665(2):293-9.
    • (1994) Brain Res , vol.665 , Issue.2 , pp. 293-299
    • Ignatowski, T.A.1    Spengler, R.N.2
  • 30
    • 0030668019 scopus 로고    scopus 로고
    • Neuronal-associated tumor necrosis factor (TNF alpha): Its role in noradrenergic functioning and modification of its expression following antidepressant drug administration
    • 1:CAS:528:DyaK2sXlsFGltr8%3D 9357451
    • Ignatowski TA, Noble BK, Wright JR, Gorfien JL, Heffner RR, Spengler RN. Neuronal-associated tumor necrosis factor (TNF alpha): its role in noradrenergic functioning and modification of its expression following antidepressant drug administration. J Neuroimmunol. 1997;79(1):84-90.
    • (1997) J Neuroimmunol , vol.79 , Issue.1 , pp. 84-90
    • Ignatowski, T.A.1    Noble, B.K.2    Wright, J.R.3    Gorfien, J.L.4    Heffner, R.R.5    Spengler, R.N.6
  • 31
    • 84897933220 scopus 로고    scopus 로고
    • Epilepsy and inflammation in the brain: Overview and pathophysiology
    • 3966641 24955068
    • Vezzani A. Epilepsy and inflammation in the brain: overview and pathophysiology. Epilepsy Curr. 2014;14(1 Suppl):3-7.
    • (2014) Epilepsy Curr , vol.14 , pp. 3-7
    • Vezzani, A.1
  • 32
    • 84899495666 scopus 로고    scopus 로고
    • Immediate neurological recovery following perispinal etanercept years after brain injury
    • 1:CAS:528:DC%2BC2cXmsV2rtL0%3D 24647830
    • Tobinick E, Rodriguez-Romanacce H, Levine A, Ignatowski TA, Spengler RN. Immediate neurological recovery following perispinal etanercept years after brain injury. Clin Drug Investig. 2014;34(5):361-6.
    • (2014) Clin Drug Investig , vol.34 , Issue.5 , pp. 361-366
    • Tobinick, E.1    Rodriguez-Romanacce, H.2    Levine, A.3    Ignatowski, T.A.4    Spengler, R.N.5
  • 33
    • 84908015088 scopus 로고    scopus 로고
    • TNF and TNF-receptors: From mediators of cell death and inflammation to therapeutic giants - Past, present and future
    • Sedger LM, McDermott MF. TNF and TNF-receptors: from mediators of cell death and inflammation to therapeutic giants - past, present and future. Cytokine Growth Factor Rev. 2014;. doi: 10.1016/j.cytogfr.2014.07.016.
    • (2014) Cytokine Growth Factor Rev
    • Sedger, L.M.1    McDermott, M.F.2
  • 34
    • 84894049144 scopus 로고    scopus 로고
    • Neuroimmune regulation of homeostatic synaptic plasticity
    • 1:CAS:528:DC%2BC3sXhtVKnsb7E 23774138
    • Pribiag H, Stellwagen D. Neuroimmune regulation of homeostatic synaptic plasticity. Neuropharmacology. 2014;78:13-22.
    • (2014) Neuropharmacology , vol.78 , pp. 13-22
    • Pribiag, H.1    Stellwagen, D.2
  • 35
    • 84902144244 scopus 로고    scopus 로고
    • Tumor necrosis factor alpha: A link between neuroinflammation and excitotoxicity
    • Olmos G, Llado J. Tumor necrosis factor alpha: a link between neuroinflammation and excitotoxicity. Mediat inflamm. 2014;2014:861231.
    • (2014) Mediat Inflamm , vol.2014 , pp. 861231
    • Olmos, G.1    Llado, J.2
  • 36
    • 84910621430 scopus 로고    scopus 로고
    • Targeting TNF: A therapeutic strategy for Alzheimer's disease
    • Cheng X, Shen Y, Li R. Targeting TNF: a therapeutic strategy for Alzheimer's disease. Drug Discov Today. 2014;. doi: 10.1016/j.drudis.2014.06.029.
    • (2014) Drug Discov Today
    • Cheng, X.1    Shen, Y.2    Li, R.3
  • 37
    • 84866751526 scopus 로고    scopus 로고
    • TNF-alpha in synaptic function: Switching gears
    • 1:CAS:528:DC%2BC38XpsVOqsLg%3D 22749718
    • Santello M, Volterra A. TNF-alpha in synaptic function: switching gears. Trends Neurosci. 2012;35(10):638-47.
    • (2012) Trends Neurosci , vol.35 , Issue.10 , pp. 638-647
    • Santello, M.1    Volterra, A.2
  • 38
    • 84922070898 scopus 로고    scopus 로고
    • Comment on: "Perispinal etanercept for post-stroke neurological and cognitive dysfunction: scientific rationale and current evidence"
    • Whitlock DR. Comment on: "Perispinal etanercept for post-stroke neurological and cognitive dysfunction: scientific rationale and current evidence". CNS Drugs. 2014. doi: 10.1007/s40263-014-0211-1.
    • (2014) CNS Drugs
    • Whitlock, D.R.1
  • 39
    • 31844443695 scopus 로고
    • The environment and disease: Association or causation?
    • 1:STN:280:DyaF2M%2FovVCmsw%3D%3D 1898525 14283879
    • Hill AB. The environment and disease: association or causation? Proc R Soc Med. 1965;58:295-300.
    • (1965) Proc R Soc Med , vol.58 , pp. 295-300
    • Hill, A.B.1
  • 40
    • 66749086365 scopus 로고    scopus 로고
    • The evolution of evidence hierarchies: What can Bradford Hill's 'guidelines for causation' contribute?
    • 2677430 19417051
    • Howick J, Glasziou P, Aronson JK. The evolution of evidence hierarchies: what can Bradford Hill's 'guidelines for causation' contribute? J R Soc Med. 2009;102(5):186-94.
    • (2009) J R Soc Med , vol.102 , Issue.5 , pp. 186-194
    • Howick, J.1    Glasziou, P.2    Aronson, J.K.3
  • 41
    • 79955778081 scopus 로고    scopus 로고
    • Evaluating treatments in health care: The instability of a one-legged stool
    • 3103483 21569350
    • Kaplan BJ, Giesbrecht G, Shannon S, McLeod K. Evaluating treatments in health care: the instability of a one-legged stool. BMC Med Res Methodol. 2011;11:65.
    • (2011) BMC Med Res Methodol , vol.11 , pp. 65
    • Kaplan, B.J.1    Giesbrecht, G.2    Shannon, S.3    McLeod, K.4
  • 42
    • 0034888957 scopus 로고    scopus 로고
    • Understanding evidence-based medicine: A primer
    • 1:STN:280:DC%2BD3MvnsFWltA%3D%3D 11518879
    • Williams JK. Understanding evidence-based medicine: a primer. Am J Obstet Gynecol. 2001;185(2):275-8.
    • (2001) Am J Obstet Gynecol , vol.185 , Issue.2 , pp. 275-278
    • Williams, J.K.1
  • 43
    • 33847152253 scopus 로고    scopus 로고
    • When are randomised trials unnecessary? Picking signal from noise
    • 1800999 17303884
    • Glasziou P, Chalmers I, Rawlins M, McCulloch P. When are randomised trials unnecessary? Picking signal from noise. BMJ. 2007;334(7589):349-51.
    • (2007) BMJ , vol.334 , Issue.7589 , pp. 349-351
    • Glasziou, P.1    Chalmers, I.2    Rawlins, M.3    McCulloch, P.4
  • 44
    • 80053277530 scopus 로고    scopus 로고
    • OCEBM Levels of Evidence Working Group Oxford Centre for Evidence-Based Medicine Accessed 9 Oct 2014
    • OCEBM Levels of Evidence Working Group. The Oxford 2011 levels of evidence. Oxford Centre for Evidence-Based Medicine. 2011. http://www.cebm.net/index.aspx?o=5653. Accessed 9 Oct 2014.
    • (2011) The Oxford 2011 Levels of Evidence
  • 45
    • 78649759142 scopus 로고    scopus 로고
    • Use of TNF blockers and other targeted therapies in rare refractory immune-mediated inflammatory diseases: Evidence-based or rational?
    • 1:CAS:528:DC%2BC3cXhs1emsb7E 20705637
    • Baeten D, van Hagen PM. Use of TNF blockers and other targeted therapies in rare refractory immune-mediated inflammatory diseases: evidence-based or rational? Ann Rheum Dis. 2010;69(12):2067-73.
    • (2010) Ann Rheum Dis , vol.69 , Issue.12 , pp. 2067-2073
    • Baeten, D.1    Van Hagen, P.M.2
  • 47
    • 84893868818 scopus 로고    scopus 로고
    • Evidence needs to be translated, whether or not it is complete
    • 24297103
    • Dacks PA, Bennett DA, Fillit HM. Evidence needs to be translated, whether or not it is complete. JAMA Neurol. 2014;71(2):137-8.
    • (2014) JAMA Neurol , vol.71 , Issue.2 , pp. 137-138
    • Dacks, P.A.1    Bennett, D.A.2    Fillit, H.M.3
  • 48
    • 78349249369 scopus 로고    scopus 로고
    • Evidence-based mechanistic reasoning
    • 2966890 21037334
    • Howick J, Glasziou P, Aronson JK. Evidence-based mechanistic reasoning. J R Soc Med. 2010;103(11):433-41.
    • (2010) J R Soc Med , vol.103 , Issue.11 , pp. 433-441
    • Howick, J.1    Glasziou, P.2    Aronson, J.K.3
  • 49
    • 23844504629 scopus 로고    scopus 로고
    • Observational versus experimental studies: What's the evidence for a hierarchy?
    • 534936 15717036
    • Concato J. Observational versus experimental studies: what's the evidence for a hierarchy? NeuroRx. 2004;1(3):341-7.
    • (2004) NeuroRx , vol.1 , Issue.3 , pp. 341-347
    • Concato, J.1
  • 50
    • 0034702175 scopus 로고    scopus 로고
    • Randomized, controlled trials, observational studies, and the hierarchy of research designs
    • 1:STN:280:DC%2BD3czgt1Chsw%3D%3D 1557642 10861325
    • Concato J, Shah N, Horwitz RI. Randomized, controlled trials, observational studies, and the hierarchy of research designs. N Engl J Med. 2000;342(25):1887-92.
    • (2000) N Engl J Med , vol.342 , Issue.25 , pp. 1887-1892
    • Concato, J.1    Shah, N.2    Horwitz, R.I.3
  • 51
    • 0142029229 scopus 로고    scopus 로고
    • The value of observational studies in neurotherapy
    • Trudeau DL. The value of observational studies in neurotherapy. J Neurother. 2001;4(3):1-4.
    • (2001) J Neurother , vol.4 , Issue.3 , pp. 1-4
    • Trudeau, D.L.1
  • 52
    • 26844470894 scopus 로고    scopus 로고
    • The randomized controlled trial: Gold standard, or merely standard?
    • 16227664
    • Grossman J, Mackenzie FJ. The randomized controlled trial: gold standard, or merely standard? Perspect Biol Med. 2005;48(4):516-34.
    • (2005) Perspect Biol Med , vol.48 , Issue.4 , pp. 516-534
    • Grossman, J.1    Mackenzie, F.J.2
  • 53
    • 33644685442 scopus 로고    scopus 로고
    • The major role of clinicians in the discovery of off-label drug therapies
    • 16503712
    • Demonaco HJ, Ali A, Hippel E. The major role of clinicians in the discovery of off-label drug therapies. Pharmacotherapy. 2006;26(3):323-32.
    • (2006) Pharmacotherapy , vol.26 , Issue.3 , pp. 323-332
    • Demonaco, H.J.1    Ali, A.2    Hippel, E.3
  • 54
    • 65649112521 scopus 로고    scopus 로고
    • The value of drug repositioning in the current pharmaceutical market
    • 19330170
    • Tobinick EL. The value of drug repositioning in the current pharmaceutical market. Drug News Perspect. 2009;22(2):119-25.
    • (2009) Drug News Perspect , vol.22 , Issue.2 , pp. 119-125
    • Tobinick, E.L.1
  • 55
    • 0028143212 scopus 로고
    • Repeated therapy with monoclonal antibody to tumour necrosis factor alpha (cA2) in patients with rheumatoid arthritis
    • 1:STN:280:DyaK2M%2FitVWkuw%3D%3D 7934495
    • Elliott MJ, Maini RN, Feldmann M, Long-Fox A, Charles P, Bijl H, et al. Repeated therapy with monoclonal antibody to tumour necrosis factor alpha (cA2) in patients with rheumatoid arthritis. Lancet. 1994;344(8930):1125-7.
    • (1994) Lancet , vol.344 , Issue.8930 , pp. 1125-1127
    • Elliott, M.J.1    Maini, R.N.2    Feldmann, M.3    Long-Fox, A.4    Charles, P.5    Bijl, H.6
  • 56
    • 0030027092 scopus 로고    scopus 로고
    • Evidence based medicine: What it is and what it isn't
    • 1:STN:280:DyaK287ktF2itw%3D%3D 2349778 8555924
    • Sackett DL, Rosenberg WM, Gray JA, Haynes RB, Richardson WS. Evidence based medicine: what it is and what it isn't. BMJ. 1996;312(7023):71-2.
    • (1996) BMJ , vol.312 , Issue.7023 , pp. 71-72
    • Sackett, D.L.1    Rosenberg, W.M.2    Gray, J.A.3    Haynes, R.B.4    Richardson, W.S.5
  • 57
    • 0032930986 scopus 로고    scopus 로고
    • Case reports in an evidence-based world
    • 1:STN:280:DyaK1MznvVKrtg%3D%3D 1297135 10450190
    • Vandenbroucke JP. Case reports in an evidence-based world. J R Soc Med. 1999;92(4):159-63.
    • (1999) J R Soc Med , vol.92 , Issue.4 , pp. 159-163
    • Vandenbroucke, J.P.1
  • 58
    • 0035916288 scopus 로고    scopus 로고
    • In defense of case reports and case series
    • 1:STN:280:DC%2BD3M7ktl2rsQ%3D%3D 11182844
    • Vandenbroucke JP. In defense of case reports and case series. Ann Intern Med. 2001;134(4):330-4.
    • (2001) Ann Intern Med , vol.134 , Issue.4 , pp. 330-334
    • Vandenbroucke, J.P.1
  • 59
    • 84879965464 scopus 로고    scopus 로고
    • In support of clinical case reports: A system of causality assessment
    • 3833527 24416665
    • Kiene H, Hamre HJ, Kienle GS. In support of clinical case reports: a system of causality assessment. Glob Adv Health Med. 2013;2(2):64-75.
    • (2013) Glob Adv Health Med , vol.2 , Issue.2 , pp. 64-75
    • Kiene, H.1    Hamre, H.J.2    Kienle, G.S.3
  • 60
    • 0346099113 scopus 로고    scopus 로고
    • Parachute use to prevent death and major trauma related to gravitational challenge: Systematic review of randomised controlled trials
    • 300808 14684649
    • Smith GC, Pell JP. Parachute use to prevent death and major trauma related to gravitational challenge: systematic review of randomised controlled trials. BMJ. 2003;327(7429):1459-61.
    • (2003) BMJ , vol.327 , Issue.7429 , pp. 1459-1461
    • Smith, G.C.1    Pell, J.P.2
  • 61
    • 45449115211 scopus 로고    scopus 로고
    • Perispinal etanercept produces rapid improvement in primary progressive aphasia: Identification of a novel, rapidly reversible TNF-mediated pathophysiologic mechanism
    • 2491668 18679537
    • Tobinick E. Perispinal etanercept produces rapid improvement in primary progressive aphasia: identification of a novel, rapidly reversible TNF-mediated pathophysiologic mechanism. Medscape J Med. 2008;10(6):135.
    • (2008) Medscape J Med , vol.10 , Issue.6 , pp. 135
    • Tobinick, E.1
  • 63
    • 84904017111 scopus 로고    scopus 로고
    • Etanercept reduces thermal and mechanical orofacial hyperalgesia following inflammation and neuropathic injury
    • 1:CAS:528:DC%2BC2cXhtFCktrrF 24399698
    • Coelho SC, Bastos-Pereira AL, Fraga D, Chichorro JG, Zampronio AR. Etanercept reduces thermal and mechanical orofacial hyperalgesia following inflammation and neuropathic injury. Eur J Pain. 2014;18(7):957-67.
    • (2014) Eur J Pain , vol.18 , Issue.7 , pp. 957-967
    • Coelho, S.C.1    Bastos-Pereira, A.L.2    Fraga, D.3    Chichorro, J.G.4    Zampronio, A.R.5
  • 64
    • 65549165150 scopus 로고    scopus 로고
    • Randomized, double-blind, placebo-controlled, dose-response, and preclinical safety study of transforaminal epidural etanercept for the treatment of sciatica
    • 1:CAS:528:DC%2BD1MXkvVGmsLg%3D 19387178
    • Cohen SP, Bogduk N, Dragovich A, Buckenmaier CC 3rd, Griffith S, Kurihara C, et al. Randomized, double-blind, placebo-controlled, dose-response, and preclinical safety study of transforaminal epidural etanercept for the treatment of sciatica. Anesthesiology. 2009;110(5):1116-26.
    • (2009) Anesthesiology , vol.110 , Issue.5 , pp. 1116-1126
    • Cohen, S.P.1    Bogduk, N.2    Dragovich, A.3    Buckenmaier, C.C.4    Griffith, S.5    Kurihara, C.6
  • 65
    • 84887303113 scopus 로고    scopus 로고
    • Randomized, double-blind, placebo-controlled, trial of transforaminal epidural etanercept for the treatment of symptomatic lumbar disc herniation
    • 24165696
    • Freeman BJ, Ludbrook GL, Hall S, Cousins M, Mitchell B, Jaros M, et al. Randomized, double-blind, placebo-controlled, trial of transforaminal epidural etanercept for the treatment of symptomatic lumbar disc herniation. Spine. 2013;38(23):1986-94.
    • (2013) Spine , vol.38 , Issue.23 , pp. 1986-1994
    • Freeman, B.J.1    Ludbrook, G.L.2    Hall, S.3    Cousins, M.4    Mitchell, B.5    Jaros, M.6
  • 67
    • 84874558778 scopus 로고    scopus 로고
    • Targeting anti-inflammatory treatment can ameliorate injury-induced neuropathic pain
    • 1:CAS:528:DC%2BC3sXjvFKgsr8%3D 3585184 23469058
    • Iwatsuki K, Arai T, Ota H, Kato S, Natsume T, Kurimoto S, et al. Targeting anti-inflammatory treatment can ameliorate injury-induced neuropathic pain. PloS One. 2013;8(2):e57721.
    • (2013) PloS One , vol.8 , Issue.2 , pp. 57721
    • Iwatsuki, K.1    Arai, T.2    Ota, H.3    Kato, S.4    Natsume, T.5    Kurimoto, S.6
  • 68
    • 64049104780 scopus 로고    scopus 로고
    • Distribution and tumor necrosis factor-alpha isoform binding specificity of locally administered etanercept into injured and uninjured rat sciatic nerve
    • 1:CAS:528:DC%2BD1MXksVSrtrk%3D 19250961
    • Kato K, Kikuchi S, Shubayev VI, Myers RR. Distribution and tumor necrosis factor-alpha isoform binding specificity of locally administered etanercept into injured and uninjured rat sciatic nerve. Neuroscience. 2009;160(2):492-500.
    • (2009) Neuroscience , vol.160 , Issue.2 , pp. 492-500
    • Kato, K.1    Kikuchi, S.2    Shubayev, V.I.3    Myers, R.R.4
  • 69
    • 84858792288 scopus 로고    scopus 로고
    • Epidural administration of spinal nerves with the tumor necrosis factor-alpha inhibitor, etanercept, compared with dexamethasone for treatment of sciatica in patients with lumbar spinal stenosis: A prospective randomized study
    • 22020607
    • Ohtori S, Miyagi M, Eguchi Y, Inoue G, Orita S, Ochiai N, et al. Epidural administration of spinal nerves with the tumor necrosis factor-alpha inhibitor, etanercept, compared with dexamethasone for treatment of sciatica in patients with lumbar spinal stenosis: a prospective randomized study. Spine. 2012;37(6):439-44.
    • (2012) Spine , vol.37 , Issue.6 , pp. 439-444
    • Ohtori, S.1    Miyagi, M.2    Eguchi, Y.3    Inoue, G.4    Orita, S.5    Ochiai, N.6
  • 70
    • 0035870863 scopus 로고    scopus 로고
    • Selective inhibition of tumor necrosis factor-alpha prevents nucleus pulposus-induced thrombus formation, intraneural edema, and reduction of nerve conduction velocity: Possible implications for future pharmacologic treatment strategies of sciatica
    • 1:STN:280:DC%2BD3MvhtVShtA%3D%3D 11317106
    • Olmarker K, Rydevik B. Selective inhibition of tumor necrosis factor-alpha prevents nucleus pulposus-induced thrombus formation, intraneural edema, and reduction of nerve conduction velocity: possible implications for future pharmacologic treatment strategies of sciatica. Spine. 2001;26(8):863-9.
    • (2001) Spine , vol.26 , Issue.8 , pp. 863-869
    • Olmarker, K.1    Rydevik, B.2
  • 71
    • 84938592812 scopus 로고    scopus 로고
    • Intradiscal administration of tumor necrosis factor-alpha inhibitor, etanercept, clinically improves intractable discogenic low back pain
    • Sainoh T, Orita S, Yamauchi K, Suzuki M, Sakuma Y, Kubota G, et al. Intradiscal administration of tumor necrosis factor-alpha inhibitor, etanercept, clinically improves intractable discogenic low back pain. Glob Spine J. 2014. doi: 10.1055/s-0034-1376544.
    • (2014) Glob Spine J.
    • Sainoh, T.1    Orita, S.2    Yamauchi, K.3    Suzuki, M.4    Sakuma, Y.5    Kubota, G.6
  • 72
    • 79251630715 scopus 로고    scopus 로고
    • Etanercept restores the antinociceptive effect of morphine and suppresses spinal neuroinflammation in morphine-tolerant rats
    • 1:CAS:528:DC%2BC3MXhtVSls7w%3D 21081778
    • Shen CH, Tsai RY, Shih MS, Lin SL, Tai YH, Chien CC, et al. Etanercept restores the antinociceptive effect of morphine and suppresses spinal neuroinflammation in morphine-tolerant rats. Anesth Analg. 2011;112(2):454-9.
    • (2011) Anesth Analg , vol.112 , Issue.2 , pp. 454-459
    • Shen, C.H.1    Tsai, R.Y.2    Shih, M.S.3    Lin, S.L.4    Tai, Y.H.5    Chien, C.C.6
  • 73
    • 0034952170 scopus 로고    scopus 로고
    • Etanercept reduces hyperalgesia in experimental painful neuropathy
    • 1:CAS:528:DC%2BD3MXltleit7w%3D 11446385
    • Sommer C, Schafers M, Marziniak M, Toyka KV. Etanercept reduces hyperalgesia in experimental painful neuropathy. J Peripher Nerv Syst. 2001;6(2):67-72.
    • (2001) J Peripher Nerv Syst , vol.6 , Issue.2 , pp. 67-72
    • Sommer, C.1    Schafers, M.2    Marziniak, M.3    Toyka, K.V.4
  • 74
    • 58849161223 scopus 로고    scopus 로고
    • Perispinal etanercept for neuroinflammatory disorders
    • 1:CAS:528:DC%2BD1MXhtlSrs78%3D 19027875
    • Tobinick E. Perispinal etanercept for neuroinflammatory disorders. Drug Discov Today. 2009;14(3-4):168-77.
    • (2009) Drug Discov Today. , vol.14 , Issue.3-4 , pp. 168-177
    • Tobinick, E.1
  • 75
    • 84878578871 scopus 로고    scopus 로고
    • Author's reply to Page. "selective TNF inhibition for chronic stroke and traumatic brain injury: An observational study involving 629 consecutive patients treated with perispinal etanercept"
    • 23580177
    • Tobinick E. Author's reply to Page. "Selective TNF inhibition for chronic stroke and traumatic brain injury: an observational study involving 629 consecutive patients treated with perispinal etanercept". CNS Drugs. 2013;27(5):399-402.
    • (2013) CNS Drugs , vol.27 , Issue.5 , pp. 399-402
    • Tobinick, E.1
  • 76
    • 0038746846 scopus 로고    scopus 로고
    • Targeted etanercept for discogenic neck pain: Uncontrolled, open-label results in two adults
    • 12809967
    • Tobinick EL. Targeted etanercept for discogenic neck pain: uncontrolled, open-label results in two adults. Clin Ther. 2003;25(4):1211-8.
    • (2003) Clin Ther , vol.25 , Issue.4 , pp. 1211-1218
    • Tobinick, E.L.1
  • 77
    • 84855192761 scopus 로고    scopus 로고
    • Etanercept attenuates pain-related behavior following compression of the dorsal root ganglion in the rat
    • 3207346 21633793
    • Watanabe K, Yabuki S, Sekiguchi M, Kikuchi S, Konno S. Etanercept attenuates pain-related behavior following compression of the dorsal root ganglion in the rat. Eur Spine J. 2011;20(11):1877-84.
    • (2011) Eur Spine J , vol.20 , Issue.11 , pp. 1877-1884
    • Watanabe, K.1    Yabuki, S.2    Sekiguchi, M.3    Kikuchi, S.4    Konno, S.5
  • 78
    • 40049098691 scopus 로고    scopus 로고
    • Effect of etanercept, a tumor necrosis factor-alpha inhibitor, on neuropathic pain in the rat chronic constriction injury model
    • 18303453
    • Zanella JM, Burright EN, Hildebrand K, Hobot C, Cox M, Christoferson L, et al. Effect of etanercept, a tumor necrosis factor-alpha inhibitor, on neuropathic pain in the rat chronic constriction injury model. Spine. 2008;33(3):227-34.
    • (2008) Spine , vol.33 , Issue.3 , pp. 227-234
    • Zanella, J.M.1    Burright, E.N.2    Hildebrand, K.3    Hobot, C.4    Cox, M.5    Christoferson, L.6
  • 79
    • 0042386708 scopus 로고    scopus 로고
    • Targeted etanercept for treatment-refractory pain due to bone metastasis: Two case reports
    • 14512134
    • Tobinick EL. Targeted etanercept for treatment-refractory pain due to bone metastasis: two case reports. Clin Ther. 2003;25(8):2279-88.
    • (2003) Clin Ther , vol.25 , Issue.8 , pp. 2279-2288
    • Tobinick, E.L.1
  • 80
    • 33644525313 scopus 로고    scopus 로고
    • The cerebrospinal venous system: Anatomy, physiology, and clinical implications
    • Tobinick E, Vega CP. The cerebrospinal venous system: anatomy, physiology, and clinical implications. Med Gen Med. 2006;8(1):53.
    • (2006) Med Gen Med , vol.8 , Issue.1 , pp. 53
    • Tobinick, E.1    Vega, C.P.2
  • 81
    • 68949205705 scopus 로고    scopus 로고
    • Tumour necrosis factor modulation for treatment of Alzheimer's disease: Rationale and current evidence
    • 1:CAS:528:DC%2BD1MXht1KiurjI 19689163
    • Tobinick E. Tumour necrosis factor modulation for treatment of Alzheimer's disease: rationale and current evidence. CNS Drugs. 2009;23(9):713-25.
    • (2009) CNS Drugs , vol.23 , Issue.9 , pp. 713-725
    • Tobinick, E.1
  • 83
    • 84907372904 scopus 로고    scopus 로고
    • Etanercept reduces neuroinflammation and lethality in mouse model of Japanese encephalitis
    • Ye J, Jiang R, Cui M, Zhu B, Sun L, Wang Y, et al. Etanercept reduces neuroinflammation and lethality in mouse model of Japanese encephalitis. J Infect Dis. 2014;210(6):875-89.
    • (2014) J Infect Dis. , vol.210 , Issue.6 , pp. 875-889
    • Ye, J.1    Jiang, R.2    Cui, M.3    Zhu, B.4    Sun, L.5    Wang, Y.6
  • 84
    • 84928692654 scopus 로고    scopus 로고
    • Chapter 19: Intervertebral disc herniation: Pathophysiology and emerging therapies
    • I.M. Shapiro M.V. Risbud (eds) Springer Wien
    • Winkelstein BA, Allen KD, Setton LA. Chapter 19: intervertebral disc herniation: pathophysiology and emerging therapies. In: Shapiro IM, Risbud MV, editors. The intervertebral disc. Wien: Springer; 2014.
    • (2014) The Intervertebral Disc
    • Winkelstein, B.A.1    Allen, K.D.2    Setton, L.A.3
  • 85
    • 84934440658 scopus 로고    scopus 로고
    • Does brain inflammation mediate pathological outcomes in epilepsy
    • Wilcox KS, Vezzani A. Does brain inflammation mediate pathological outcomes in epilepsy? Adv Exp Med Biol. 2014;813:169-83.
    • (2014) Adv Exp Med Biol. , vol.813 , pp. 169-183
    • Wilcox, K.S.1    Vezzani, A.2
  • 86
    • 84900833175 scopus 로고    scopus 로고
    • Research progress in traumatic brain penumbra
    • 24824264
    • Wang K, Liu B, Ma J. Research progress in traumatic brain penumbra. Chin Med J. 2014;127(10):1964-8.
    • (2014) Chin Med J , vol.127 , Issue.10 , pp. 1964-1968
    • Wang, K.1    Liu, B.2    Ma, J.3
  • 87
    • 84904755354 scopus 로고    scopus 로고
    • Neuroinflammatory contributions to pain after SCI: Roles for central glial mechanisms and nociceptor-mediated host defense
    • Walters ET. Neuroinflammatory contributions to pain after SCI: roles for central glial mechanisms and nociceptor-mediated host defense. Exp Neurol. 2014;258C:48-61.
    • (2014) Exp Neurol , vol.258 , pp. 48-61
    • Walters, E.T.1
  • 88
    • 84905911087 scopus 로고    scopus 로고
    • Perspectives on neuroinflammation and excitotoxicity: A neurotoxic conspiracy
    • Viviani B, Boraso M, Marchetti N, Marinovich M. Perspectives on neuroinflammation and excitotoxicity: a neurotoxic conspiracy? Neurotoxicology. 2014;43:10-20.
    • (2014) Neurotoxicology , vol.43 , pp. 10-20
    • Viviani, B.1    Boraso, M.2    Marchetti, N.3    Marinovich, M.4
  • 89
    • 85038934825 scopus 로고    scopus 로고
    • The effect of etanercept and methylprednisolone on functional recovery of the facial nerve after crush injury
    • Topdag M, Iseri M, Topdag DO, Kokturk S, Ozturk M, Iseri P. The effect of etanercept and methylprednisolone on functional recovery of the facial nerve after crush injury. Otol Neurotol. 2014;35(7):1277-83.
    • (2014) Otol Neurotol. , vol.35 , Issue.7 , pp. 1277-1283
    • Topdag, M.1    Iseri, M.2    Topdag, D.O.3    Kokturk, S.4    Ozturk, M.5    Iseri, P.6
  • 90
    • 84910659639 scopus 로고    scopus 로고
    • Increased plasma TACE activity in subjects with mild cognitive impairment and patients with Alzheimer's disease
    • 1:CAS:528:DC%2BC2cXht1Sqt73L
    • Sun Q, Hampel H, Blennow K, Lista S, Levey A, Tang B, et al. Increased plasma TACE activity in subjects with mild cognitive impairment and patients with Alzheimer's disease. J Alzheimer's Dis. 2014;41(3):877-86.
    • (2014) J Alzheimer's Dis , vol.41 , Issue.3 , pp. 877-886
    • Sun, Q.1    Hampel, H.2    Blennow, K.3    Lista, S.4    Levey, A.5    Tang, B.6
  • 92
    • 84930378357 scopus 로고    scopus 로고
    • Pathomechanisms of discogenic low back pain in humans and animal models
    • Ohtori S, Inoue G, Miyagi M, Takahashi K. Pathomechanisms of discogenic low back pain in humans and animal models. Spine J. 2014;. doi: 10.1016/j.spinee.2013.07.490.
    • (2014) Spine J
    • Ohtori, S.1    Inoue, G.2    Miyagi, M.3    Takahashi, K.4
  • 93
    • 84907167305 scopus 로고    scopus 로고
    • Insulin resistance, neuroinflammation, and Alzheimer's disease
    • Najem D, Bamji-Mirza M, Chang N, Liu QY, Zhang W. Insulin resistance, neuroinflammation, and Alzheimer's disease. Rev Neurosci. 2014;25(4):509-25.
    • (2014) Rev Neurosci. , vol.25 , Issue.4 , pp. 509-525
    • Najem, D.1    Bamji-Mirza, M.2    Chang, N.3    Liu, Q.Y.4    Zhang, W.5
  • 94
    • 84939889855 scopus 로고    scopus 로고
    • Intracerebral hemorrhage in mouse models: Therapeutic interventions and functional recovery
    • Kathirvelu B, Carmichael ST. Intracerebral hemorrhage in mouse models: therapeutic interventions and functional recovery. Metab Brain Dis. 2014;. doi: 10.1007/s11011-014-9559-7.
    • (2014) Metab Brain Dis
    • Kathirvelu, B.1    Carmichael, S.T.2
  • 95
    • 84916937601 scopus 로고    scopus 로고
    • Venous drainage of the spine and spinal cord: A comprehensive review of its history, embryology, anatomy, physiology, and pathology
    • Griessenauer CJ, Raborn J, Foreman P, Shoja MM, Loukas M, Tubbs RS. Venous drainage of the spine and spinal cord: a comprehensive review of its history, embryology, anatomy, physiology, and pathology. Clin Anat. 2014;. doi: 10.1002/ca.22354.
    • (2014) Clin Anat
    • Griessenauer, C.J.1    Raborn, J.2    Foreman, P.3    Shoja, M.M.4    Loukas, M.5    Tubbs, R.S.6
  • 96
    • 84896705983 scopus 로고    scopus 로고
    • Mild cognitive impairment in patients with moderate to severe chronic plaque psoriasis
    • 24434720
    • Gisondi P, Sala F, Alessandrini F, Avesani V, Zoccatelli G, Beltramello A, et al. Mild cognitive impairment in patients with moderate to severe chronic plaque psoriasis. Dermatology. 2014;228(1):78-85.
    • (2014) Dermatology , vol.228 , Issue.1 , pp. 78-85
    • Gisondi, P.1    Sala, F.2    Alessandrini, F.3    Avesani, V.4    Zoccatelli, G.5    Beltramello, A.6
  • 98
    • 84902233345 scopus 로고    scopus 로고
    • Network control mechanisms: Cellular inputs, neuroactive substances, and synaptic changes
    • Faingold CL, Blumenfeld H, editors CNS Disorders, and Therapeutics: Elsevier
    • Faingold CL. Network control mechanisms: cellular inputs, neuroactive substances, and synaptic changes. In: Faingold CL, Blumenfeld H, editors. Neuronal networks in brain function. CNS Disorders, and Therapeutics: Elsevier; 2014.
    • (2014) Neuronal Networks in Brain Function
    • Faingold, C.L.1
  • 99
    • 84896953262 scopus 로고    scopus 로고
    • Effect of etanercept and lithium chloride on preventing secondary tissue damage in rats with experimental diffuse severe brain injury
    • Ekici MA, Uysal O, Cikriklar HI, Ozbek Z, Turgut Cosan D, Baydemir C, et al. Effect of etanercept and lithium chloride on preventing secondary tissue damage in rats with experimental diffuse severe brain injury. Eur Rev Med Pharmacol Sci. 2014;18(1):10-27.
    • (2014) Eur Rev Med Pharmacol Sci. , vol.18 , Issue.1 , pp. 10-27
    • Ma, E.1    Uysal, O.2    Cikriklar, H.I.3    Ozbek, Z.4    Turgut Cosan, D.5    Baydemir, C.6
  • 100
    • 84899516623 scopus 로고    scopus 로고
    • Peripheral administration of an anti-TNF-alpha receptor fusion protein counteracts the amyloid induced elevation of hippocampal TNF-alpha levels and memory deficits in mice
    • Detrait ER, Danis B, Lamberty Y, Foerch P. Peripheral administration of an anti-TNF-alpha receptor fusion protein counteracts the amyloid induced elevation of hippocampal TNF-alpha levels and memory deficits in mice. Neurochem Int. 2014;. doi: 10.1016/j.neuint.2014.04.001.
    • (2014) Neurochem Int
    • Detrait, E.R.1    Danis, B.2    Lamberty, Y.3    Foerch, P.4
  • 101
    • 84878769054 scopus 로고    scopus 로고
    • Therapeutic strategies for tau mediated neurodegeneration
    • 3912572 23085937
    • Yoshiyama Y, Lee VM, Trojanowski JQ. Therapeutic strategies for tau mediated neurodegeneration. J Neurol Neurosurg Psychiatry. 2013;84(7):784-95.
    • (2013) J Neurol Neurosurg Psychiatry , vol.84 , Issue.7 , pp. 784-795
    • Yoshiyama, Y.1    Lee, V.M.2    Trojanowski, J.Q.3
  • 102
    • 84883743305 scopus 로고    scopus 로고
    • Soluble TNF receptor 1-secreting ex vivo-derived dendritic cells reduce injury after stroke
    • Works MG, Koenig JB, Sapolsky RM. Soluble TNF receptor 1-secreting ex vivo-derived dendritic cells reduce injury after stroke. J Cereb Blood Flow Metab. 2013;33(9):1376-85.
    • (2013) J Cereb Blood Flow Metab. , vol.33 , Issue.9 , pp. 1376-1385
    • Works, M.G.1    Koenig, J.B.2    Sapolsky, R.M.3
  • 103
    • 84885575240 scopus 로고    scopus 로고
    • Cytokine gene polymorphisms and outcome after traumatic brain injury
    • 3796334 23768161
    • Waters RJ, Murray GD, Teasdale GM, Stewart J, Day I, Lee RJ, et al. Cytokine gene polymorphisms and outcome after traumatic brain injury. J Neurotrauma. 2013;30(20):1710-6.
    • (2013) J Neurotrauma , vol.30 , Issue.20 , pp. 1710-1716
    • Waters, R.J.1    Murray, G.D.2    Teasdale, G.M.3    Stewart, J.4    Day, I.5    Lee, R.J.6
  • 105
    • 84891023522 scopus 로고    scopus 로고
    • Inhibition of the inflammatory cytokine tumor necrosis factor-alpha with etanercept provides protection against lethal H1N1 influenza infection in mice
    • 4057515 24373231
    • Shi X, Zhou W, Huang H, Zhu H, Zhou P, Zhu H, et al. Inhibition of the inflammatory cytokine tumor necrosis factor-alpha with etanercept provides protection against lethal H1N1 influenza infection in mice. Critical Care. 2013;17(6):R301.
    • (2013) Critical Care , vol.17 , Issue.6 , pp. 301
    • Shi, X.1    Zhou, W.2    Huang, H.3    Zhu, H.4    Zhou, P.5    Zhu, H.6
  • 107
    • 84883239904 scopus 로고    scopus 로고
    • Tumor necrosis factor alpha antagonism improves neurological recovery in murine intracerebral hemorrhage
    • Lei B, Dawson HN, Roulhac-Wilson B, Wang H, Laskowitz DT, James ML. Tumor necrosis factor alpha antagonism improves neurological recovery in murine intracerebral hemorrhage. J Neuroinflamm. 2013;10(1):103.
    • (2013) J Neuroinflamm , vol.10 , Issue.1 , pp. 103
    • Lei, B.1    Dawson, H.N.2    Roulhac-Wilson, B.3    Wang, H.4    Laskowitz, D.T.5    James, M.L.6
  • 108
    • 84905015047 scopus 로고    scopus 로고
    • Biochemistry of back pain
    • Kaufman EL, Carl A. Biochemistry of back pain. Open Spine J. 2013;5:12-8.
    • (2013) Open Spine J , vol.5 , pp. 12-18
    • Kaufman, E.L.1    Carl, A.2
  • 109
    • 84873397447 scopus 로고    scopus 로고
    • Inflammation and white matter degeneration persist for years after a single traumatic brain injury
    • 3562078 23365092
    • Johnson VE, Stewart JE, Begbie FD, Trojanowski JQ, Smith DH, Stewart W. Inflammation and white matter degeneration persist for years after a single traumatic brain injury. Brain. 2013;136(Pt 1):28-42.
    • (2013) Brain , vol.136 , pp. 28-42
    • Johnson, V.E.1    Stewart, J.E.2    Begbie, F.D.3    Trojanowski, J.Q.4    Smith, D.H.5    Stewart, W.6
  • 111
    • 84872415494 scopus 로고    scopus 로고
    • Hyperbaric oxygen induces late neuroplasticity in post stroke patients: Randomized, prospective trial
    • 1:CAS:528:DC%2BC3sXhsFWqtbc%3D 3546039 23335971
    • Efrati S, Fishlev G, Bechor Y, Volkov O, Bergan J, Kliakhandler K, et al. Hyperbaric oxygen induces late neuroplasticity in post stroke patients: randomized, prospective trial. PloS One. 2013;8(1):e53716.
    • (2013) PloS One , vol.8 , Issue.1 , pp. 53716
    • Efrati, S.1    Fishlev, G.2    Bechor, Y.3    Volkov, O.4    Bergan, J.5    Kliakhandler, K.6
  • 112
    • 84884704633 scopus 로고    scopus 로고
    • Treatment implications of the altered cytokine-insulin axis in neurodegenerative disease
    • 1:CAS:528:DC%2BC3sXhtlCntb%2FN 23939185
    • Clark IA, Vissel B. Treatment implications of the altered cytokine-insulin axis in neurodegenerative disease. Biochem Pharmacol. 2013;86(7):862-71.
    • (2013) Biochem Pharmacol , vol.86 , Issue.7 , pp. 862-871
    • Clark, I.A.1    Vissel, B.2
  • 113
    • 84874943964 scopus 로고    scopus 로고
    • Etanercept attenuates traumatic brain injury in rats by reducing early microglial expression of tumor necrosis factor-alpha
    • 1:CAS:528:DC%2BC3sXnvFahsbk%3D 3636122 23496862
    • Chio CC, Chang CH, Wang CC, Cheong CU, Chao CM, Cheng BC, et al. Etanercept attenuates traumatic brain injury in rats by reducing early microglial expression of tumor necrosis factor-alpha. BMC Neurosci. 2013;14(1):33.
    • (2013) BMC Neurosci , vol.14 , Issue.1 , pp. 33
    • Chio, C.C.1    Chang, C.H.2    Wang, C.C.3    Cheong, C.U.4    Chao, C.M.5    Cheng, B.C.6
  • 114
    • 84877952603 scopus 로고    scopus 로고
    • Etanercept attenuates traumatic brain injury in rats by reducing brain TNF-alpha contents and by stimulating newly formed neurogenesis
    • Cheong CU, Chang CP, Chao CM, Cheng BC, Yang CZ, Chio CC. Etanercept attenuates traumatic brain injury in rats by reducing brain TNF-alpha contents and by stimulating newly formed neurogenesis. Mediat Inflamm. 2013;2013:620837.
    • (2013) Mediat Inflamm , vol.2013 , pp. 620837
    • Cheong, C.U.1    Chang, C.P.2    Chao, C.M.3    Cheng, B.C.4    Yang, C.Z.5    Chio, C.C.6
  • 115
    • 84883461678 scopus 로고    scopus 로고
    • The liver-brain axis in liver failure: Neuroinflammation and encephalopathy
    • 1:CAS:528:DC%2BC3sXhsVWqs77E
    • Butterworth RF. The liver-brain axis in liver failure: neuroinflammation and encephalopathy. Nature Rev Gastroenterol Hepatol. 2013;10(9):522-8.
    • (2013) Nature Rev Gastroenterol Hepatol , vol.10 , Issue.9 , pp. 522-528
    • Butterworth, R.F.1
  • 116
    • 84874606434 scopus 로고    scopus 로고
    • Astrocyte signaling and neurodegeneration: New insights into CNS disorders
    • 1:CAS:528:DC%2BC3sXksFWku74%3D 3609047 23093800
    • Brambilla L, Martorana F, Rossi D. Astrocyte signaling and neurodegeneration: new insights into CNS disorders. Prion. 2013;7(1):28-36.
    • (2013) Prion , vol.7 , Issue.1 , pp. 28-36
    • Brambilla, L.1    Martorana, F.2    Rossi, D.3
  • 117
    • 84887202012 scopus 로고    scopus 로고
    • The combination of valacyclovir with an anti-TNF alpha antibody (etanercept) increases survival rate compared to antiviral therapy alone in a murine model of herpes simplex virus encephalitis
    • 1:CAS:528:DC%2BC3sXhvVWks7jJ 24416771
    • Boivin N, Menasria R, Piret J, Rivest S, Boivin G. The combination of valacyclovir with an anti-TNF alpha antibody (etanercept) increases survival rate compared to antiviral therapy alone in a murine model of herpes simplex virus encephalitis. Antivir Res. 2013;100(3):649-53.
    • (2013) Antivir Res , vol.100 , Issue.3 , pp. 649-653
    • Boivin, N.1    Menasria, R.2    Piret, J.3    Rivest, S.4    Boivin, G.5
  • 118
    • 84875139027 scopus 로고    scopus 로고
    • Immunology primer for neurosurgeons and neurologists part 2: Innate brain immunity
    • 3784951 24083053
    • Blaylock RL. Immunology primer for neurosurgeons and neurologists part 2: innate brain immunity. Surg Neurol Int. 2013;4:118.
    • (2013) Surg Neurol Int , vol.4 , pp. 118
    • Blaylock, R.L.1
  • 119
    • 84879504934 scopus 로고    scopus 로고
    • Elevated plasma levels of soluble TNFRs and TACE activity in Alzheimer's disease patients of northern Han Chinese descent
    • 1:CAS:528:DC%2BC3sXktFemu7g%3D 23368432
    • Bai L, Song N, Yu J, Tan L, Shen Y, Xie J, et al. Elevated plasma levels of soluble TNFRs and TACE activity in Alzheimer's disease patients of northern Han Chinese descent. Curr Alzheimer Res. 2013;10(1):57-62.
    • (2013) Curr Alzheimer Res , vol.10 , Issue.1 , pp. 57-62
    • Bai, L.1    Song, N.2    Yu, J.3    Tan, L.4    Shen, Y.5    Xie, J.6
  • 120
    • 84865175827 scopus 로고    scopus 로고
    • Historical perspectives on the discovery and development of drugs to treat neurological disorders
    • J.E. Barrett J.T. Coyle M. Williams (eds) Cambridge University Press New York
    • Williams M, Coyle JT. Historical perspectives on the discovery and development of drugs to treat neurological disorders. In: Barrett JE, Coyle JT, Williams M, editors. Translational neuroscience: applications in psychiatry, neurology, and neurodevelopmental disorders. New York: Cambridge University Press; 2012. p. 129-48.
    • (2012) Translational Neuroscience: Applications in Psychiatry, Neurology, and Neurodevelopmental Disorders , pp. 129-148
    • Williams, M.1    Coyle, J.T.2
  • 121
    • 84873444843 scopus 로고    scopus 로고
    • New hope for survivors of stroke and traumatic brain injury
    • 23100197
    • Clark I. New hope for survivors of stroke and traumatic brain injury. CNS Drugs. 2012;26(12):1071-2.
    • (2012) CNS Drugs , vol.26 , Issue.12 , pp. 1071-1072
    • Clark, I.1
  • 122
    • 84867051523 scopus 로고    scopus 로고
    • Tumor necrosis factor-induced cerebral insulin resistance in Alzheimer's disease links numerous treatment rationales
    • 1:CAS:528:DC%2BC3sXhslalug%3D%3D 22966039
    • Clark I, Atwood C, Bowen R, Paz-Filho G, Vissel B. Tumor necrosis factor-induced cerebral insulin resistance in Alzheimer's disease links numerous treatment rationales. Pharmacol Rev. 2012;64(4):1004-26.
    • (2012) Pharmacol Rev , vol.64 , Issue.4 , pp. 1004-1026
    • Clark, I.1    Atwood, C.2    Bowen, R.3    Paz-Filho, G.4    Vissel, B.5
  • 123
    • 0342902205 scopus 로고    scopus 로고
    • Is the placebo powerless? An analysis of clinical trials comparing placebo with no treatment
    • 1:STN:280:DC%2BD3M3ptFSkug%3D%3D 11372012
    • Hrobjartsson A, Gotzsche PC. Is the placebo powerless? An analysis of clinical trials comparing placebo with no treatment. N Engl J Med. 2001;344(21):1594-602.
    • (2001) N Engl J Med , vol.344 , Issue.21 , pp. 1594-1602
    • Hrobjartsson, A.1    Gotzsche, P.C.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.