Optimized microwave assisted synthesis of LL37, a cathelicidin human antimicrobial peptide

International Journal of Peptide Research and Therapeutics

Volumn 21, Issue 1, 2015, Pages 13-20

  Dutta, Jyotibon ^a   Ramesh, Suhas ^a   Radebe, Siduduzo M ^a   Somboro, Anou M ^a   De La Torre, Beatriz G ^a,b   Kruger, Hendrik G ^a   Essack, Sabiha Y ^a   Albericio, Fernando ^a,b,c,d   Govender, Thavendran ^a  

^a UNIVERSITY OF KWAZULU NATAL   (South Africa)

^b YACHAY TECH UNIVERSITY   (Ecuador)

^c INSTITUTE FOR RESEARCH IN BIOMEDICINE   (Spain)

^d UNIVERSITY OF BARCELONA   (Spain)

Author keywords

DIC; LL37; Microwave; OxymaPure; SPPS; THF

Indexed keywords

1 [BIS(DIMETHYLAMINO)METHYLENE] 1H 1,2,3 RIAZOLO[4,5 B]PYRIDINIUM 3 OXIDHEXAFLUOROPHOSPHATE; CATHELICIDIN ANTIMICROBIAL PEPTIDE LL 37; CYANAMIDE; ETHYLAMINE; ISOLEUCINE; N [(1H BENZOTRIAZOL 1 YL)(DIMETHYLAMINO)METHYLENE] N METHYLMETHANAMINIUM HEXAFLUOROPHOSPHATE N OXIDE; N,N DIISOPROPYLETHYLAMINE; N,N' DIISOPROPYLCARBODIIMIDE; REAGENT; TETRAHYDROFURAN; UNCLASSIFIED DRUG; VALINE;

AMIDE BOND; ANTIBACTERIAL ACTIVITY; ANTIBIOTIC SENSITIVITY; ARTICLE; CHEMICAL BOND; CHEMICAL REACTION; CONTROLLED STUDY; DOUBLE COUPLING; DRUG PURIFICATION; DRUG SYNTHESIS; ENTEROCOCCUS FAECALIS; ESCHERICHIA COLI; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; MICROWAVE ASSISTED SOLID PHASE PEPTIDE SYNTHESIS; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; PROCESS OPTIMIZATION; SALMONELLA ENTERICA SUBSP. ENTERICA; STAPHYLOCOCCUS AUREUS;

EID: 84922070972     PISSN: 15733149     EISSN: 15733904     Source Type: Journal    
DOI: 10.1007/s10989-014-9439-3     Document Type: Article

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