Non hemolytic short peptidomimetics as a new class of potent and broad-spectrum antimicrobial agents

Bioorganic and Medicinal Chemistry Letters

Volumn 23, Issue 16, 2013, Pages 4633-4636

  Murugan, Ravichandran N ^a   Jacob, Binu ^b   Kim, Eun Hee ^a   Ahn, Mija ^a   Sohn, Hoik ^c   Seo, Ji Hyung ^a   Cheong, Chaejoon ^a   Hyun, Jae Kyung ^a   Lee, Kyung S ^d   Shin, Song Yub ^b   Bang, Jeong Kyu ^a  

^a Korea Basic Science Institute (KBSI)   (South Korea)

^b Chosun University   (South Korea)

^c University of Texas at Austin   (United States)

^d NATIONAL CANCER INSTITUTE   (United States)

Author keywords

Methicillin resistance Staphylococcus aureus; Proteolytic stability; Short antimicrobial peptidomimetics

Indexed keywords

ANTIINFECTIVE AGENT; PEPTIDOMIMETIC AGENT;

ANTIMICROBIAL ACTIVITY; ARTICLE; COST EFFECTIVENESS ANALYSIS; DRUG CYTOTOXICITY; DRUG POTENCY; ESCHERICHIA COLI; ESTERIFICATION; HEMOLYSIS; HUMAN; HUMAN CELL; HUMAN TISSUE; HYDROPHILICITY; HYDROPHOBICITY; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS; NONHUMAN; PHARMACOPHORE; PROTEIN DEGRADATION; PROTEIN STABILITY; PSEUDOMONAS AERUGINOSA; SOLID PHASE SYNTHESIS; STAPHYLOCOCCUS EPIDERMIDIS; STRUCTURE ACTIVITY RELATION;

METHICILLIN-RESISTANCE STAPHYLOCOCCUS AUREUS; PROTEOLYTIC STABILITY; SHORT ANTIMICROBIAL PEPTIDOMIMETICS;

ANTI-INFECTIVE AGENTS; HEMOLYSIS; METHICILLIN-RESISTANT STAPHYLOCOCCUS AUREUS; MICROBIAL SENSITIVITY TESTS; PEPTIDOMIMETICS; PROTEIN STABILITY;

BACTERIA (MICROORGANISMS); METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS; STAPHYLOCOCCUS AUREUS;

EID: 84880590971     PISSN: 0960894X     EISSN: 14643405     Source Type: Journal    
DOI: 10.1016/j.bmcl.2013.06.016     Document Type: Article

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