Cytotoxic effects of escin on human castration-resistant prostate cancer cells through the induction of apoptosis and G2/M cell cycle arrest

Urology

Volumn 84, Issue 4, 2014, Pages 982.e1-982.e7

  Piao, Songzhe ^a,b   Kang, Minyong ^a   Lee, Young Ju ^a   Choi, Woo Suk ^c   Chun, Yang Sook ^d   Kwak, Cheol ^a   Kim, Hyeon Hoe ^a  

^a Seoul National University Hospital   (South Korea)

^b YANBIAN UNIVERSITY   (China)

^c Konkuk University Hospital   (South Korea)

^d Seoul National University College of Medicine   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE 3; CYCLIN B1; CYCLIN DEPENDENT KINASE 1; ESCIN; INHIBITOR OF APOPTOSIS PROTEIN 1; INHIBITOR OF APOPTOSIS PROTEIN 2; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PROTEIN BAX; PROTEIN BCL 2; PROTEIN BCL XL; PROTEIN P21; X LINKED INHIBITOR OF APOPTOSIS;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; ANTIPROLIFERATIVE ACTIVITY; APOPTOSIS; ARTICLE; B CELL LEUKEMIA; B CELL LYMPHOMA; CANCER INHIBITION; CASTRATION RESISTANT PROSTATE CANCER; CELL PROLIFERATION; CELL VIABILITY; CONTROLLED STUDY; DOSE RESPONSE; DRUG EFFICACY; DRUG MEGADOSE; FLOW CYTOMETRY; G2 PHASE CELL CYCLE CHECKPOINT; HISTOPATHOLOGY; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; IN VIVO STUDY; LOW DRUG DOSE; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROSTATE CANCER CELL LINE; PROTEIN CLEAVAGE; PROTEIN EXPRESSION; TREATMENT DURATION; TUMOR MODEL; TUMOR XENOGRAFT; WESTERN BLOTTING;

EID: 84922063748     PISSN: 00904295     EISSN: 15279995     Source Type: Journal    
DOI: 10.1016/j.urology.2014.06.019     Document Type: Article

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