메뉴 건너뛰기




Volumn 25, Issue 2, 2015, Pages 195-201

The natural compound berberine positively affects macrophage functions involved in atherogenesis

Author keywords

Atherosclerosis; Berberine; Cholesterol; Inflammation; Macrophages

Indexed keywords

BERBERINE; CHOLESTEROL OXIDASE; MONOCYTE CHEMOTACTIC PROTEIN 1; CHOLESTEROL; HYPOCHOLESTEROLEMIC AGENT;

EID: 84922012276     PISSN: 09394753     EISSN: 15903729     Source Type: Journal    
DOI: 10.1016/j.numecd.2014.08.004     Document Type: Article
Times cited : (36)

References (29)
  • 1
    • 66349130447 scopus 로고    scopus 로고
    • Regulation of macrophage function in inflammation and atherosclerosis
    • Shibata N., Glass C.K. Regulation of macrophage function in inflammation and atherosclerosis. J Lipid Res 2009, (50 Suppl.):S277-S281. 10.1194/jlr.R800063-JLR200.
    • (2009) J Lipid Res , Issue.SUPPL.50 , pp. S277-S281
    • Shibata, N.1    Glass, C.K.2
  • 2
    • 0025182576 scopus 로고
    • Metabolism of cholesteryl ester lipid droplets in a J774 macrophage foam cell model
    • Mahlberg F.H., Glick J.M., Jerome W.G., Rothblat G.H. Metabolism of cholesteryl ester lipid droplets in a J774 macrophage foam cell model. Biochim Biophys Acta 1990, 1045:291-298.
    • (1990) Biochim Biophys Acta , vol.1045 , pp. 291-298
    • Mahlberg, F.H.1    Glick, J.M.2    Jerome, W.G.3    Rothblat, G.H.4
  • 3
    • 20444461628 scopus 로고    scopus 로고
    • Free cholesterol-loaded macrophages are an abundant source of tumor necrosis factor-alpha and interleukin-6: model of NF-kappaB- and map kinase-dependent inflammation in advanced atherosclerosis
    • Li Y., Schwabe R.F., DeVries-Seimon T., Yao P.M., Gerbod-Giannone M.C., Tall A.R., et al. Free cholesterol-loaded macrophages are an abundant source of tumor necrosis factor-alpha and interleukin-6: model of NF-kappaB- and map kinase-dependent inflammation in advanced atherosclerosis. J Biol Chem 2005, 280:21763-21772. 10.1074/jbc.M501759200.
    • (2005) J Biol Chem , vol.280 , pp. 21763-21772
    • Li, Y.1    Schwabe, R.F.2    DeVries-Seimon, T.3    Yao, P.M.4    Gerbod-Giannone, M.C.5    Tall, A.R.6
  • 4
    • 79959732295 scopus 로고    scopus 로고
    • Nrf2 is essential for cholesterol crystal-induced inflammasome activation and exacerbation of atherosclerosis
    • Freigang S., Ampenberger F., Spohn G., Heer S., Shamshiev A.T., Kisielow J., et al. Nrf2 is essential for cholesterol crystal-induced inflammasome activation and exacerbation of atherosclerosis. Eur J Immunol 2011, 41:2040-2051. 10.1002/eji.201041316.
    • (2011) Eur J Immunol , vol.41 , pp. 2040-2051
    • Freigang, S.1    Ampenberger, F.2    Spohn, G.3    Heer, S.4    Shamshiev, A.T.5    Kisielow, J.6
  • 5
    • 33644866644 scopus 로고    scopus 로고
    • Elevated plasma membrane cholesterol content alters macrophage signaling and function
    • Qin C., Nagao T., Grosheva I., Maxfield F.R., Pierini L.M. Elevated plasma membrane cholesterol content alters macrophage signaling and function. Arterioscler Thromb Vasc Biol 2006, 26:372-378. 10.1161/01.ATV.0000197848.67999.e1.
    • (2006) Arterioscler Thromb Vasc Biol , vol.26 , pp. 372-378
    • Qin, C.1    Nagao, T.2    Grosheva, I.3    Maxfield, F.R.4    Pierini, L.M.5
  • 6
    • 79952102640 scopus 로고    scopus 로고
    • Free cholesterol alters macrophage morphology and mobility by an ABCA1 dependent mechanism
    • Adorni M.P., Favari E., Ronda N., Granata A., Bellosta S., Arnaboldi L., et al. Free cholesterol alters macrophage morphology and mobility by an ABCA1 dependent mechanism. Atherosclerosis 2011, 215:70-76. 10.1016/j.atherosclerosis.2010.12.004.
    • (2011) Atherosclerosis , vol.215 , pp. 70-76
    • Adorni, M.P.1    Favari, E.2    Ronda, N.3    Granata, A.4    Bellosta, S.5    Arnaboldi, L.6
  • 7
    • 77952769142 scopus 로고    scopus 로고
    • Antiatherogenic properties of flavonoids: implications for cardiovascular health
    • A:17A-21A
    • Mulvihill E.E., Huff M.W. Antiatherogenic properties of flavonoids: implications for cardiovascular health. Can J Cardiol 2010, (26 Suppl.). A:17A-21A.
    • (2010) Can J Cardiol
    • Mulvihill, E.E.1    Huff, M.W.2
  • 8
    • 19944374769 scopus 로고    scopus 로고
    • Berberine is a novel cholesterol-lowering drug working through a unique mechanism distinct from statins
    • Kong W., Wei J., Abidi P., Lin M., Inaba S., Li C., et al. Berberine is a novel cholesterol-lowering drug working through a unique mechanism distinct from statins. Nat Med 2004, 10:1344-1351. 10.1038/nm1135.
    • (2004) Nat Med , vol.10 , pp. 1344-1351
    • Kong, W.1    Wei, J.2    Abidi, P.3    Lin, M.4    Inaba, S.5    Li, C.6
  • 9
    • 84876679315 scopus 로고    scopus 로고
    • The effects of berberine on blood lipids: a systemic review and meta-analysis of randomized controlled trials
    • Dong H., Zhao Y., Zhao L., Lu F. The effects of berberine on blood lipids: a systemic review and meta-analysis of randomized controlled trials. Planta Med 2013, 79:437-446. 10.1055/s-0032-1328321.
    • (2013) Planta Med , vol.79 , pp. 437-446
    • Dong, H.1    Zhao, Y.2    Zhao, L.3    Lu, F.4
  • 10
    • 84893982496 scopus 로고    scopus 로고
    • Nutraceutical approach to moderate cardiometabolic risk: results of a randomized, double-blind and crossover study with armolipid plus
    • Ruscica M., Gomaraschi M., Mombelli G., Macchi C., Bosisio R., Pazzucconi F., et al. Nutraceutical approach to moderate cardiometabolic risk: results of a randomized, double-blind and crossover study with armolipid plus. J Clin Lipidol 2014, 8:61-68. 10.1016/j.jacl.2013.11.003.
    • (2014) J Clin Lipidol , vol.8 , pp. 61-68
    • Ruscica, M.1    Gomaraschi, M.2    Mombelli, G.3    Macchi, C.4    Bosisio, R.5    Pazzucconi, F.6
  • 11
    • 84864429088 scopus 로고    scopus 로고
    • Berberine-induced inhibition of adipocyte enhancer-binding protein 1 attenuates oxidized low-density lipoprotein accumulation and foam cell formation in phorbol 12-myristate 13-acetate-induced macrophages
    • Huang Z., Dong F., Li S., Chu M., Zhou H., Lu Z., et al. Berberine-induced inhibition of adipocyte enhancer-binding protein 1 attenuates oxidized low-density lipoprotein accumulation and foam cell formation in phorbol 12-myristate 13-acetate-induced macrophages. Eur J Pharmacol 2012, 690:164-169. 10.1016/j.ejphar.2012.07.009.
    • (2012) Eur J Pharmacol , vol.690 , pp. 164-169
    • Huang, Z.1    Dong, F.2    Li, S.3    Chu, M.4    Zhou, H.5    Lu, Z.6
  • 12
    • 78149417658 scopus 로고    scopus 로고
    • Effects of berberine on expression of LOX-1 and SR-BI in human macrophage-derived foam cells induced by ox-LDL
    • Guan S., Wang B., Li W., Guan J., Fang X. Effects of berberine on expression of LOX-1 and SR-BI in human macrophage-derived foam cells induced by ox-LDL. Am J Chin Med 2010, 38:1161-1169. 10.1142/S0192415X10008548.
    • (2010) Am J Chin Med , vol.38 , pp. 1161-1169
    • Guan, S.1    Wang, B.2    Li, W.3    Guan, J.4    Fang, X.5
  • 13
    • 83655181347 scopus 로고    scopus 로고
    • Suppression of oxLDL-induced MMP-9 and EMMPRIN expression by berberine via inhibition of NF-kappaB activation in human THP-1 macrophages
    • Huang Z., Meng S., Wang L., Wang Y., Chen T., Wang C. Suppression of oxLDL-induced MMP-9 and EMMPRIN expression by berberine via inhibition of NF-kappaB activation in human THP-1 macrophages. Anat Rec Hob 2012, 295:78-86. 10.1002/ar.21489.
    • (2012) Anat Rec Hob , vol.295 , pp. 78-86
    • Huang, Z.1    Meng, S.2    Wang, L.3    Wang, Y.4    Chen, T.5    Wang, C.6
  • 14
    • 78650657270 scopus 로고    scopus 로고
    • Berberine reduces both MMP-9 and EMMPRIN expression through prevention of p38 pathway activation in PMA-induced macrophages
    • Huang Z., Wang L., Meng S., Wang Y., Chen T., Wang C. Berberine reduces both MMP-9 and EMMPRIN expression through prevention of p38 pathway activation in PMA-induced macrophages. Int J Cardiol 2011, 146:153-158. 10.1016/j.ijcard.2009.06.023.
    • (2011) Int J Cardiol , vol.146 , pp. 153-158
    • Huang, Z.1    Wang, L.2    Meng, S.3    Wang, Y.4    Chen, T.5    Wang, C.6
  • 15
    • 67449096759 scopus 로고    scopus 로고
    • Berberine inhibits the expression of TNFalpha, MCP-1, and IL-6 in AcLDL-stimulated macrophages through PPARgamma pathway
    • Chen F.L., Yang Z.H., Liu Y., Li L.X., Liang W.C., Wang X.C., et al. Berberine inhibits the expression of TNFalpha, MCP-1, and IL-6 in AcLDL-stimulated macrophages through PPARgamma pathway. Endocrine 2008, 33:331-337. 10.1007/s12020-008-9089-3.
    • (2008) Endocrine , vol.33 , pp. 331-337
    • Chen, F.L.1    Yang, Z.H.2    Liu, Y.3    Li, L.X.4    Liang, W.C.5    Wang, X.C.6
  • 16
    • 0018178434 scopus 로고
    • A modification of the Lowry procedure to simplify protein determination in membrane and lipoprotein samples
    • doi:0003-2697(78)90586-9
    • Markwell M.A., Haas S.M., Bieber L.L., Tolbert N.E. A modification of the Lowry procedure to simplify protein determination in membrane and lipoprotein samples. Anal Biochem 1978, 87:206-210. doi:0003-2697(78)90586-9.
    • (1978) Anal Biochem , vol.87 , pp. 206-210
    • Markwell, M.A.1    Haas, S.M.2    Bieber, L.L.3    Tolbert, N.E.4
  • 18
    • 0344896671 scopus 로고    scopus 로고
    • Cytotoxic cellular cholesterol is selectively removed by apoA-I via ABCA1
    • doi:S0021915003003642
    • Kellner-Weibel G., Luke S.J., Rothblat G.H. Cytotoxic cellular cholesterol is selectively removed by apoA-I via ABCA1. Atherosclerosis 2003, 171:235-243. doi:S0021915003003642.
    • (2003) Atherosclerosis , vol.171 , pp. 235-243
    • Kellner-Weibel, G.1    Luke, S.J.2    Rothblat, G.H.3
  • 19
    • 27944510124 scopus 로고    scopus 로고
    • Impaired ATP-binding cassette transporter A1-mediated sterol efflux from oxidized LDL-loaded macrophages
    • Favari E., Zimetti F., Bortnick A.E., Adorni M.P., Zanotti I., Canavesi M., et al. Impaired ATP-binding cassette transporter A1-mediated sterol efflux from oxidized LDL-loaded macrophages. FEBS Lett 2005, 579:6537-6542. 10.1016/j.febslet.2005.10.042.
    • (2005) FEBS Lett , vol.579 , pp. 6537-6542
    • Favari, E.1    Zimetti, F.2    Bortnick, A.E.3    Adorni, M.P.4    Zanotti, I.5    Canavesi, M.6
  • 20
    • 33644757667 scopus 로고    scopus 로고
    • Measurement of cholesterol bidirectional flux between cells and lipoproteins
    • Zimetti F., Weibel G.K., Duong M., Rothblat G.H. Measurement of cholesterol bidirectional flux between cells and lipoproteins. J Lipid Res 2006, 47:605-613. 10.1194/jlr.M500466-JLR200.
    • (2006) J Lipid Res , vol.47 , pp. 605-613
    • Zimetti, F.1    Weibel, G.K.2    Duong, M.3    Rothblat, G.H.4
  • 21
    • 35848954726 scopus 로고    scopus 로고
    • The roles of different pathways in the release of cholesterol from macrophages
    • Adorni M.P., Zimetti F., Billheimer J.T., Wang N., Rader D.J., Phillips M.C., et al. The roles of different pathways in the release of cholesterol from macrophages. J Lipid Res 2007, 48:2453-2462. 10.1194/jlr.M700274-JLR200.
    • (2007) J Lipid Res , vol.48 , pp. 2453-2462
    • Adorni, M.P.1    Zimetti, F.2    Billheimer, J.T.3    Wang, N.4    Rader, D.J.5    Phillips, M.C.6
  • 22
    • 84877135349 scopus 로고    scopus 로고
    • Fluid-phase pinocytosis of LDL by macrophages: a novel target to reduce macrophage cholesterol accumulation in atherosclerotic lesions
    • doi:CPD-EPUB-20130215-4
    • Kruth H.S. Fluid-phase pinocytosis of LDL by macrophages: a novel target to reduce macrophage cholesterol accumulation in atherosclerotic lesions. Curr Pharm Des 2013, 19:5865-5872. doi:CPD-EPUB-20130215-4.
    • (2013) Curr Pharm Des , vol.19 , pp. 5865-5872
    • Kruth, H.S.1
  • 23
    • 83455224354 scopus 로고    scopus 로고
    • Eicosapentaenoic acid and docosahexaenoic acid regulate modified LDL uptake and macropinocytosis in human macrophages
    • McLaren J.E., Michael D.R., Guschina I.A., Harwood J.L., Ramji D.P. Eicosapentaenoic acid and docosahexaenoic acid regulate modified LDL uptake and macropinocytosis in human macrophages. Lipids 2011, 46:1053-1061. 10.1007/s11745-011-3598-1.
    • (2011) Lipids , vol.46 , pp. 1053-1061
    • McLaren, J.E.1    Michael, D.R.2    Guschina, I.A.3    Harwood, J.L.4    Ramji, D.P.5
  • 24
    • 0032870291 scopus 로고    scopus 로고
    • Cytotoxic cholesterol is generated by the hydrolysis of cytoplasmic cholesteryl ester and transported to the plasma membrane
    • doi:S0021915099001550
    • Kellner-Weibel G., Geng Y.J., Rothblat G.H. Cytotoxic cholesterol is generated by the hydrolysis of cytoplasmic cholesteryl ester and transported to the plasma membrane. Atherosclerosis 1999, 146:309-319. doi:S0021915099001550.
    • (1999) Atherosclerosis , vol.146 , pp. 309-319
    • Kellner-Weibel, G.1    Geng, Y.J.2    Rothblat, G.H.3
  • 25
    • 0017222289 scopus 로고
    • The LDL pathway in human fibroblasts: a receptor-mediated mechanism for the regulation of cholesterol metabolism
    • Goldstein J.L., Brown M.S. The LDL pathway in human fibroblasts: a receptor-mediated mechanism for the regulation of cholesterol metabolism. Curr Top Cell Regul 1976, 11:147-181.
    • (1976) Curr Top Cell Regul , vol.11 , pp. 147-181
    • Goldstein, J.L.1    Brown, M.S.2
  • 26
    • 0022334353 scopus 로고
    • The LDL receptor and the regulation of cellular cholesterol metabolism
    • Goldstein J.L., Brown M.S. The LDL receptor and the regulation of cellular cholesterol metabolism. J Cell Sci Suppl 1985, 3:131-137.
    • (1985) J Cell Sci Suppl , vol.3 , pp. 131-137
    • Goldstein, J.L.1    Brown, M.S.2
  • 27
    • 67650711138 scopus 로고    scopus 로고
    • Mechanisms of endocytosis
    • Doherty G.J., McMahon H.T. Mechanisms of endocytosis. Annu Rev Biochem 2009, 78:857-902. 10.1146/annurev.biochem.78.081307.110540.
    • (2009) Annu Rev Biochem , vol.78 , pp. 857-902
    • Doherty, G.J.1    McMahon, H.T.2
  • 28
    • 77957147716 scopus 로고    scopus 로고
    • Anti-atherogenic effect of berberine on LXRalpha-ABCA1-dependent cholesterol efflux in macrophages
    • Lee T.S., Pan C.C., Peng C.C., Kou Y.R., Chen C.Y., Ching L.C., et al. Anti-atherogenic effect of berberine on LXRalpha-ABCA1-dependent cholesterol efflux in macrophages. J Cell Biochem 2011, 111:104-110. 10.1002/jcb.22667.
    • (2011) J Cell Biochem , vol.111 , pp. 104-110
    • Lee, T.S.1    Pan, C.C.2    Peng, C.C.3    Kou, Y.R.4    Chen, C.Y.5    Ching, L.C.6
  • 29
    • 0029116986 scopus 로고
    • HMG-CoA reductase inhibitors reduce acetyl LDL endocytosis in mouse peritoneal macrophages
    • Bernini F., Scurati N., Bonfadini G., Fumagalli R. HMG-CoA reductase inhibitors reduce acetyl LDL endocytosis in mouse peritoneal macrophages. Arterioscler Thromb Vasc Biol 1995, 15:1352-1358.
    • (1995) Arterioscler Thromb Vasc Biol , vol.15 , pp. 1352-1358
    • Bernini, F.1    Scurati, N.2    Bonfadini, G.3    Fumagalli, R.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.