-
1
-
-
34047143696
-
Stepwise replication identifies a low-producing lymphotoxin-alpha allele as a major risk factor for early-onset leprosy
-
COI: 1:CAS:528:DC%2BD2sXjsV2hs7o%3D, PID: 17353895
-
Alcais A et al (2007) Stepwise replication identifies a low-producing lymphotoxin-alpha allele as a major risk factor for early-onset leprosy. Nat Genet 39:517–522. doi:10.1038/ng2000
-
(2007)
Nat Genet
, vol.39
, pp. 517-522
-
-
Alcais, A.1
-
2
-
-
79951550529
-
Leprosy as a genetic disease
-
COI: 1:CAS:528:DC%2BC3MXht1Whsbs%3D, PID: 20936290
-
Alter A, Grant A, Abel L, Alcais A, Schurr E (2011) Leprosy as a genetic disease. Mamm Genome 22:19–31. doi:10.1007/s00335-010-9287-1
-
(2011)
Mamm Genome
, vol.22
, pp. 19-31
-
-
Alter, A.1
Grant, A.2
Abel, L.3
Alcais, A.4
Schurr, E.5
-
3
-
-
13444269543
-
Haploview: analysis and visualization of LD and haplotype maps
-
COI: 1:CAS:528:DC%2BD2MXkt1WitQ%3D%3D, PID: 15297300
-
Barrett JC, Fry B, Maller J, Daly MJ (2005) Haploview: analysis and visualization of LD and haplotype maps. Bioinformatics 21:263–265. doi:10.1093/bioinformatics/bth457
-
(2005)
Bioinformatics
, vol.21
, pp. 263-265
-
-
Barrett, J.C.1
Fry, B.2
Maller, J.3
Daly, M.J.4
-
4
-
-
77950954449
-
Common polymorphisms in the NOD2 gene region are associated with leprosy and its reactive states
-
COI: 1:CAS:528:DC%2BC3cXmtlSmtLs%3D, PID: 20350193
-
Berrington WR et al (2010) Common polymorphisms in the NOD2 gene region are associated with leprosy and its reactive states. J Infect Dis 201:1422–1435. doi:10.1086/651559
-
(2010)
J Infect Dis
, vol.201
, pp. 1422-1435
-
-
Berrington, W.R.1
-
5
-
-
1842686127
-
Leprosy
-
PID: 15081655
-
Britton WJ, Lockwood DN (2004) Leprosy. Lancet 363:1209–1219. doi:10.1016/S0140-6736(04)15952-7
-
(2004)
Lancet
, vol.363
, pp. 1209-1219
-
-
Britton, W.J.1
Lockwood, D.N.2
-
6
-
-
79956159649
-
TNF-308G>A single nucleotide polymorphism is associated with leprosy among Brazilians: a genetic epidemiology assessment, meta-analysis, and functional study
-
COI: 1:CAS:528:DC%2BC3MXht1SitLbM, PID: 21917899
-
Cardoso CC et al (2011a) TNF-308G>A single nucleotide polymorphism is associated with leprosy among Brazilians: a genetic epidemiology assessment, meta-analysis, and functional study. J Infect Dis 204:1256–1263. doi:10.1093/infdis/jir521
-
(2011)
J Infect Dis
, vol.204
, pp. 1256-1263
-
-
Cardoso, C.C.1
-
7
-
-
79956078781
-
Leprosy susceptibility: genetic variations regulate innate and adaptive immunity, and disease outcome
-
COI: 1:CAS:528:DC%2BC3MXmt1yltrs%3D, PID: 21585261
-
Cardoso CC, Pereira AC, de Sales Marques C, Moraes MO (2011b) Leprosy susceptibility: genetic variations regulate innate and adaptive immunity, and disease outcome. Future Microbiol 6:533–549. doi:10.2217/fmb.11.39->
-
(2011)
Future Microbiol
, vol.6
, pp. 533-549
-
-
Cardoso, C.C.1
Pereira, A.C.2
de Sales Marques, C.3
Moraes, M.O.4
-
8
-
-
84878528770
-
Toll-like receptor 1 N248S single-nucleotide polymorphism is associated with leprosy risk and regulates immune activation during mycobacterial infection
-
CdS Marques et al (2013) Toll-like receptor 1 N248S single-nucleotide polymorphism is associated with leprosy risk and regulates immune activation during mycobacterial infection. J Infect Dis 208:120–129. doi:10.1093/infdis/jit133
-
(2013)
J Infect Dis
, vol.208
, pp. 120-129
-
-
CdS, M.1
-
9
-
-
73849151394
-
NOD2 stimulation induces autophagy in dendritic cells influencing bacterial handling and antigen presentation
-
COI: 1:CAS:528:DC%2BD1MXhsFWksb3L, PID: 19966812
-
Cooney R et al (2010) NOD2 stimulation induces autophagy in dendritic cells influencing bacterial handling and antigen presentation. Nat Med 16:90–97. doi:10.1038/nm.2069
-
(2010)
Nat Med
, vol.16
, pp. 90-97
-
-
Cooney, R.1
-
10
-
-
84869037440
-
Crohn’s disease susceptibility genes are associated with leprosy in the Vietnamese population
-
COI: 1:CAS:528:DC%2BC38Xhs1CqsbvL, PID: 22984114
-
Grant AV et al (2012) Crohn’s disease susceptibility genes are associated with leprosy in the Vietnamese population. J Infect Dis 206:1763–1767. doi:10.1093/infdis/jis588
-
(2012)
J Infect Dis
, vol.206
, pp. 1763-1767
-
-
Grant, A.V.1
-
11
-
-
0035055544
-
The family based association test method: strategies for studying general genotype–phenotype associations
-
COI: 1:CAS:528:DC%2BD3MXjsVWgsb8%3D, PID: 11313775
-
Horvath S, Xu X, Laird NM (2001) The family based association test method: strategies for studying general genotype–phenotype associations. Eur J Hum Genet 9:301–306. doi:10.1038/sj.ejhg.5200625
-
(2001)
Eur J Hum Genet
, vol.9
, pp. 301-306
-
-
Horvath, S.1
Xu, X.2
Laird, N.M.3
-
12
-
-
79959524146
-
A haplotype map of the human genome
-
International HapMap C
-
International HapMap C (2005) A haplotype map of the human genome. Nature 437:1299–1320. doi:10.1038/nature04226
-
(2005)
Nature
, vol.437
, pp. 1299-1320
-
-
-
13
-
-
0026090668
-
A rapid procedure for extracting genomic DNA from leukocytes
-
COI: 1:CAS:528:DyaK3MXhtl2itbg%3D, PID: 2014181
-
John SW, Weitzner G, Rozen R, Scriver CR (1991) A rapid procedure for extracting genomic DNA from leukocytes. Nucleic Acids Res 19:408
-
(1991)
Nucleic Acids Res
, vol.19
, pp. 408
-
-
John, S.W.1
Weitzner, G.2
Rozen, R.3
Scriver, C.R.4
-
14
-
-
18144415857
-
Integrating case–control and TDT studies
-
COI: 1:STN:280:DC%2BD2M3htVyqug%3D%3D, PID: 15845037
-
Kazeem GR, Farrall M (2005) Integrating case–control and TDT studies. Ann Hum Genet 69:329–335. doi:10.1046/j.1529-8817.2005.00156.x
-
(2005)
Ann Hum Genet
, vol.69
, pp. 329-335
-
-
Kazeem, G.R.1
Farrall, M.2
-
15
-
-
0033652887
-
Family-based tests of association in the presence of linkage
-
COI: 1:STN:280:DC%2BD3M%2Fos1Whtg%3D%3D, PID: 11058432
-
Lake SL, Blacker D, Laird NM (2000) Family-based tests of association in the presence of linkage. Am J Hum Genet 67:1515–1525
-
(2000)
Am J Hum Genet
, vol.67
, pp. 1515-1525
-
-
Lake, S.L.1
Blacker, D.2
Laird, N.M.3
-
16
-
-
77951923057
-
A major gene controls leprosy susceptibility in a hyperendemic isolated population from north of Brazil
-
PID: 20388034
-
Lazaro FP et al (2010) A major gene controls leprosy susceptibility in a hyperendemic isolated population from north of Brazil. J Infect Dis 201:1598–1605. doi:10.1086/652007
-
(2010)
J Infect Dis
, vol.201
, pp. 1598-1605
-
-
Lazaro, F.P.1
-
17
-
-
84868492064
-
Identification of IL18RAP/IL18R1 and IL12B as leprosy risk genes demonstrates shared pathogenesis between inflammation and infectious diseases
-
COI: 1:CAS:528:DC%2BC38XhsF2hsbjE, PID: 23103228
-
Liu H et al (2012) Identification of IL18RAP/IL18R1 and IL12B as leprosy risk genes demonstrates shared pathogenesis between inflammation and infectious diseases. Am J Hum Genet 91:935–941. doi:10.1016/j.ajhg.2012.09.010
-
(2012)
Am J Hum Genet
, vol.91
, pp. 935-941
-
-
Liu, H.1
-
18
-
-
84872008654
-
A genome-wide perspective of human diversity and its implications in infectious disease
-
PID: 23284079
-
Manry J, Quintana-Murci L (2013) A genome-wide perspective of human diversity and its implications in infectious disease. Cold Spring Harb Perspect Med 3:a012450. doi:10.1101/cshperspect.a012450
-
(2013)
Cold Spring Harb Perspect Med
, vol.3
, pp. a012450
-
-
Manry, J.1
Quintana-Murci, L.2
-
19
-
-
0037370482
-
Chromosome 6q25 is linked to susceptibility to leprosy in a Vietnamese population
-
COI: 1:CAS:528:DC%2BD3sXhsV2kurw%3D, PID: 12577057
-
Mira MT et al (2003) Chromosome 6q25 is linked to susceptibility to leprosy in a Vietnamese population. Nat Genet 33:412–415. doi:10.1038/ng1096
-
(2003)
Nat Genet
, vol.33
, pp. 412-415
-
-
Mira, M.T.1
-
20
-
-
10744220764
-
Susceptibility to leprosy is associated with PARK2 and PACRG
-
COI: 1:CAS:528:DC%2BD2cXhtFCnu7g%3D, PID: 14737177
-
Mira MT et al (2004) Susceptibility to leprosy is associated with PARK2 and PACRG. Nature 427:636–640. doi:10.1038/nature02326
-
(2004)
Nature
, vol.427
, pp. 636-640
-
-
Mira, M.T.1
-
21
-
-
70549103951
-
Comparative genomic and phylogeographic analysis of Mycobacterium leprae
-
COI: 1:CAS:528:DC%2BD1MXhtlers7bO, PID: 19881526
-
Monot M et al (2009) Comparative genomic and phylogeographic analysis of Mycobacterium leprae. Nat Genet 41:1282–1289. doi:10.1038/ng.477
-
(2009)
Nat Genet
, vol.41
, pp. 1282-1289
-
-
Monot, M.1
-
22
-
-
79958109557
-
Genetics of infectious diseases: hidden etiologies and common pathways
-
COI: 1:CAS:528:DC%2BC3MXhsVWhsb3L, PID: 21619464
-
Orlova M, Di Pietrantonio T, Schurr E (2011) Genetics of infectious diseases: hidden etiologies and common pathways. Clin Chem Lab Med 49:1427–1437. doi:10.1515/CCLM.2011.620
-
(2011)
Clin Chem Lab Med
, vol.49
, pp. 1427-1437
-
-
Orlova, M.1
Di Pietrantonio, T.2
Schurr, E.3
-
23
-
-
61849147420
-
Genetic, epidemiological and biological analysis of interleukin-10 promoter single-nucleotide polymorphisms suggests a definitive role for −819C/T in leprosy susceptibility
-
COI: 1:CAS:528:DC%2BD1MXisFeltL4%3D, PID: 19110537
-
Pereira AC et al (2009) Genetic, epidemiological and biological analysis of interleukin-10 promoter single-nucleotide polymorphisms suggests a definitive role for −819C/T in leprosy susceptibility. Genes Immun 10:174–180. doi:10.1038/gene.2008.97
-
(2009)
Genes Immun
, vol.10
, pp. 174-180
-
-
Pereira, A.C.1
-
25
-
-
0013931934
-
Classification of leprosy according to immunity. A five-group system
-
COI: 1:STN:280:DyaF2s%2FhtVWluw%3D%3D, PID: 5950347
-
Ridley DS, Jopling WH (1966) Classification of leprosy according to immunity. A five-group system. Int J Lepr Other Mycobact Dis 34:255–273
-
(1966)
Int J Lepr Other Mycobact Dis
, vol.34
, pp. 255-273
-
-
Ridley, D.S.1
Jopling, W.H.2
-
26
-
-
0032231911
-
Use of parents, sibs, and unrelated controls for detection of associations between genetic markers and disease
-
COI: 1:STN:280:DyaK1M%2FhtFaksg%3D%3D, PID: 9792877
-
Schaid DJ, Rowland C (1998) Use of parents, sibs, and unrelated controls for detection of associations between genetic markers and disease. Am J Hum Genet 63:1492–1506. doi:10.1086/302094
-
(1998)
Am J Hum Genet
, vol.63
, pp. 1492-1506
-
-
Schaid, D.J.1
Rowland, C.2
-
27
-
-
84862805230
-
NOD2 triggers an interleukin-32-dependent human dendritic cell program in leprosy
-
COI: 1:CAS:528:DC%2BC38XksVemsrk%3D, PID: 22447076
-
Schenk M et al (2012) NOD2 triggers an interleukin-32-dependent human dendritic cell program in leprosy. Nat Med 18:555–563. doi:10.1038/nm.2650
-
(2012)
Nat Med
, vol.18
, pp. 555-563
-
-
Schenk, M.1
-
28
-
-
84880294680
-
Genome-wide comparison of medieval and modern Mycobacterium leprae
-
COI: 1:CAS:528:DC%2BC3sXhtVOku73K, PID: 23765279
-
Schuenemann VJ et al (2013) Genome-wide comparison of medieval and modern Mycobacterium leprae. Science 341:179–183. doi:10.1126/science.1238286
-
(2013)
Science
, vol.341
, pp. 179-183
-
-
Schuenemann, V.J.1
-
29
-
-
74049118029
-
A common genetic fingerprint in leprosy and Crohn’s disease?
-
COI: 1:CAS:528:DC%2BC3cXjtFGlsA%3D%3D, PID: 20018963
-
Schurr E, Gros P (2009) A common genetic fingerprint in leprosy and Crohn’s disease? N Engl J Med 361:2666–2668. doi:10.1056/NEJMe0910690
-
(2009)
N Engl J Med
, vol.361
, pp. 2666-2668
-
-
Schurr, E.1
Gros, P.2
-
30
-
-
0035065541
-
A major susceptibility locus for leprosy in India maps to chromosome 10p13
-
COI: 1:CAS:528:DC%2BD3MXjtFShsLk%3D, PID: 11279529
-
Siddiqui MR et al (2001) A major susceptibility locus for leprosy in India maps to chromosome 10p13. Nat Genet 27:439–441. doi:10.1038/86958
-
(2001)
Nat Genet
, vol.27
, pp. 439-441
-
-
Siddiqui, M.R.1
-
31
-
-
84881484502
-
Fine-mapping, gene expression and splicing analysis of the disease associated LRRK2 locus
-
COI: 1:CAS:528:DC%2BC3sXhtlaqsLvN, PID: 23967090
-
Trabzuni D et al (2013) Fine-mapping, gene expression and splicing analysis of the disease associated LRRK2 locus. PLoS One 8:e70724. doi:10.1371/journal.pone.0070724
-
(2013)
PLoS One
, vol.8
, pp. e70724
-
-
Trabzuni, D.1
-
32
-
-
79956053765
-
A major gene effect controls resistance to caries
-
COI: 1:STN:280:DC%2BC3MvpvVCmsg%3D%3D, PID: 21364090
-
Werneck RI et al (2011) A major gene effect controls resistance to caries. J Dent Res 90:735–739. doi:10.1177/0022034510397614
-
(2011)
J Dent Res
, vol.90
, pp. 735-739
-
-
Werneck, R.I.1
-
33
-
-
84906965742
-
Global leprosy update, 2013; reducing disease burden
-
WHO (2014) Global leprosy update, 2013; reducing disease burden. Wkly Epidemiol Rec 89:389–400
-
(2014)
Wkly Epidemiol Rec
, vol.89
, pp. 389-400
-
-
WHO1
-
34
-
-
77950972193
-
Genomewide association study of leprosy
-
India–Africa–United Kingdom Leprosy Genetics C COI: 1:CAS:528:DC%2BC3cXkslahtr4%3D, PID: 20393182, (author reply 1447–1448)
-
Wong SH, Hill AV, Vannberg FO, India–Africa–United Kingdom Leprosy Genetics C (2010) Genomewide association study of leprosy. N Engl J Med 362:1446–1447. doi:10.1056/NEJMc1001451 (author reply 1447–1448)
-
(2010)
N Engl J Med
, vol.362
, pp. 1446-1447
-
-
Wong, S.H.1
Hill, A.V.2
Vannberg, F.O.3
-
35
-
-
74049127960
-
Genomewide association study of leprosy
-
COI: 1:CAS:528:DC%2BC3cXjsFSmtg%3D%3D, PID: 20018961
-
Zhang FR et al (2009) Genomewide association study of leprosy. N Engl J Med 361:2609–2618. doi:10.1056/NEJMoa0903753
-
(2009)
N Engl J Med
, vol.361
, pp. 2609-2618
-
-
Zhang, F.R.1
-
36
-
-
82255179222
-
Identification of two new loci at IL23R and RAB32 that influence susceptibility to leprosy
-
COI: 1:CAS:528:DC%2BC3MXhtlGksL7E, PID: 22019778
-
Zhang F et al (2011) Identification of two new loci at IL23R and RAB32 that influence susceptibility to leprosy. Nat Genet 43:1247–1251. doi:10.1038/ng.973
-
(2011)
Nat Genet
, vol.43
, pp. 1247-1251
-
-
Zhang, F.1
|