Adipocyte-specific disruption of fat-specific protein 27 causes hepatosteatosis and insulin resistance in high-fat diet-fed mice

Journal of Biological Chemistry

Volumn 290, Issue 5, 2015, Pages 3092-3105

  Tanaka, Naoki ^a,c   Takahashi, Shogo ^a   Matsubara, Tsutomu ^a,d   Jiang, Changtao ^a   Sakamoto, Wataru ^b   Chanturiya, Tatyana ^b   Teng, Ruifeng ^b   Gavrilova, Oksana ^b   Gonzalez, Frank J ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

^b NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

^c SHINSHU UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^d OSAKA CITY UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

DROPS; FATTY ACIDS; FLUORINE; GENE EXPRESSION; GENES; INSULIN; MOLECULAR WEIGHT; NUTRITION; PROTEINS; TISSUE; TISSUE HOMEOSTASIS;

ENERGY HOMEOSTASIS; ENERGY RESERVOIRS; EXPRESSION LEVELS; FAT ACCUMULATION; INSULIN RESISTANCE; LIPOLYTIC ACTIVITY; NON-ALCOHOLIC FATTY LIVER DISEASE; WHITE ADIPOSE TISSUES;

MAMMALS;

ALANINE AMINOTRANSFERASE; FAT DROPLET; FAT SPECIFIC PROTEIN 27; FATTY ACID; INSULIN; MEMBRANE PROTEIN; TRIACYLGLYCEROL; UNCLASSIFIED DRUG; FAT-SPECIFIC PROTEIN 27, MOUSE; PROTEIN;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BODY COMPOSITION; BODY WEIGHT; BROWN ADIPOSE TISSUE; CONTROLLED STUDY; DYSLIPIDEMIA; ENERGY BALANCE; ENERGY EXPENDITURE; FATTY ACID BLOOD LEVEL; FATTY LIVER; FEMALE; FSP27 GENE; GENE; GENE DISRUPTION; GENE EXPRESSION; GLUCOSE HOMEOSTASIS; IN VIVO STUDY; INSULIN BLOOD LEVEL; INSULIN RESISTANCE; LIPID DIET; LIPID METABOLISM; LIPID STORAGE; LIPOLYSIS; MALE; METABOLIC PARAMETERS; MITOCHONDRION; MOUSE; NONHUMAN; OBESITY; OXYGEN CONSUMPTION; PROTEIN FUNCTION; TRIACYLGLYCEROL BLOOD LEVEL; WHITE ADIPOSE TISSUE; ADIPOCYTE; ADVERSE EFFECTS; ANIMAL; GENETICS; LIVER CELL; METABOLISM; MUTANT MOUSE STRAIN; PATHOLOGY; PHYSIOLOGY;

MUS;

ADIPOCYTES; ANIMALS; DIET, HIGH-FAT; FATTY LIVER; HEPATOCYTES; INSULIN RESISTANCE; MALE; MICE; MICE, MUTANT STRAINS; PROTEINS;

EID: 84921921686     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M114.605980     Document Type: Article

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