Roles of MicroRNAs in cancers and development

RNA Interference: Challenges and Therapeutic Opportunities

Volumn , Issue , 2014, Pages 375-413

  Takasaki, Shigeru ^a  

^a TOYO UNIVERSITY   (Japan)

Author keywords

Cancer; Cis Regulatory elements; Drosophila melanogaster; Embryo development; Gene silencing; MiRNA; Noncoding RNA; Oncogenic; Significance test; Suppressive

Indexed keywords

EID: 84921827482     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1007/978-1-4939-1538-5_24     Document Type: Chapter

References (53)

1. Aravin A, Logos-Quintana M, Yalcin A, Zavolan M, Marks D, Snyder B, Gaasterland T, Meyer J, Tuschl T (2003) The small RNA profile during Drosophila melanogaster development. Dev Cell 5:337-350.
2. Bartel DP (2004) MicroRNAs: genomics, biogenesis, mechanism, and function. Cell 116:281-297.
3. Doench JG, Sharp PA (2004) Specificity of microRNA target selection in translational repression. Genes Dev 18:504-511.
4. Lai EC (2002) Micro RNAs are complementary to 3' UTR sequence motifs that mediate negative post-transcriptional regulation. Nat Genet 30:363-364.
5. Volinia S, Calin GA, Liu CG et al (2006) A microRNA expression signature of human solid tumors defines cancer gene targets. Proc Natl Acad Sci U S A 103:2257-2261.
6. Chan JA, Krichevsky AM, Kosik KS (2005) MicroRNA-21 is an antiapoptotic factor inhuman glioblastoma cells. Cancer Res 65:6029-6033.
7. Takeshita F, Mina Y, Nagahara S et al (2005) Efficient delivery of small interfering RNA to bone-metastatic tumors by using atelocollagen in vivo. Proc Natl Acad Sci U S A 102:12177-12182.
8. Calin GA, Ferracin M, Cimmino A et al (2005) A microRNA signature associated with prognosis and progression in chronic lymphocytic leukemia. N Eng J Med 353:1793-1801.
9. Saito Y, Liang G, Egger G et al (2006) Specific activation of microRNA-127 with downregulation of the proto-oncogene BCL-6 by chromatin-modifying drugs in human cancer cells. Cancer Cell 9:435-443.
10. Takamizawa J, Konishi H, Yanagisawa K et al (2004) Reduced expression of the let-7 microRNAs in human lung cancers in association with shortened postoperative survival. Cancer Res 64:3753-3756.
11. Zhang HH, Wang XJ, Li GX et al (2007) Deletion of let-7a microRNA by real time PCR in gastric carcinoma. World J Gastroenterol 13:2883-2888.
12. Yanaihara N, Caplen N, Bowman E et al (2006) Unique microRNA molecular profiles in lung cancer diagnosis and prognosis. Cancer Cell 9:189-198.
13. Feber A, Xi L, Luketich JD et al (2008) MicroRNA expression profiles of esophageal cancer. J Thoracic Cardiovasc Surg 135:255-260.
14. Bandres E, Cubedo E, Agirre X et al (2006) Identification by real-time PCR of 13 mature microRNAs differentially expressed in colorectal cancer and non-tumoral tissues. Mol Cancer 5:29.
15. Gramantieri L, Ferracin M, Fornari F et al (2007) Cyclin G1 is a target of miR-122a, a microRNA frequency down-regulated in human hepatocellular carcinoma. Cancer Res 67:6092-6099.
16. Michael MZ, O'Conner SM, van Holst Pellekaan NG et al (2003) Reduced accumulation of specific microRNAs in colorectal neoplasia. Mol Cancer Res 1:882-891.
17. Meng F, Henson R, Wehbe-Janek H et al (2007) MicroRNA-21 regulates expression of the PTEN tumor suppressor gene in human hepatocellular cancer. Gastroenterology 133:647-658.
18. Murakami Y, Yasuda T, Saigo K et al (2006) Comprehensive analysis of microRNA expression patterns in hepatocellular carcinoma and nontumorous tissues. Oncogene 25:2537-2545.
19. Esquela-kerscher A, Slack FJ (2006) Oncomirs-microRNAs with a role in cancer. Nat Rev Cancer 6:259-269.
20. Lui WO, Pourmand N, Patterson BK, Fire A (2007) Patterns of known and novel small RNAs in human cervical cancer. Cancer Res 67:6031-6043.
21. Akao Y, Nakagawa Y, Kitade Y et al (2007) Downregulation of microRNAs-143 and -145 in B-cell malignancies. Cancer Sci 98:1914-1920.
22. Calin GA, Dumitru CD, Shimizu M et al (2002) Frequent deletions and down-regulation of micro-RNA genes miR15 and miR16 at 13q14 in chronic lymphocytic leukemia. Proc Natl Acad Sci U S A 99:15524-15529.
23. Calin GA, Croce CM (2006) MicroRNA signatures in human cancers. Nat Rev Cancer 6:857-866.
24. Calin GA, Sevignani C, Dumitru CD et al (2004) Human microRNA genes are frequently located at fragile sites and genomic regions involved in cancers. Proc Natl Acad Sci U S A 101:2999-3004.
25. Calin CA, Liu CG, Sevignani C et al (2004) MicroRNA profiling reveals distinct signatures in B cell chronic lymphocytic leukemias. Proc Natl Acad Sci U S A 101:11755-11760.
26. Osaki M, Takeshita F, Ochiya T (2008) MicroRNAs as biomarkers and therapeutic drugs in human cancer. Biomarkers 13:658-670.
27. Griffiths-Jones S, Grocock RJ, van Dongen S, Bateman A, Enright AJ (2006) miRBase:microRNA sequences, targets and gene nomenclature. Nucleic Acids Res 34:D140-D144
28. Kozomara A, Griffiths-Jones S (2010) miRBase:integrating microRNA annotation and deep-sequencing data. Nucleic Acids Res 39:D152-D157
29. Lee RC, Feinbaum RL, Ambros V (1993) The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14. Cell 75:843-854.
30. Wightman B, Ha I, Ruvkun G (1993) Posttranscriptional regulation of the heterochronic gene lin-14 by lin-4 mediates temporal pattern formation in C. elegans. Cell 75:855-862.
31. Enright AJ, John B, Gaul U, Tuschl T, Sander C, Marks DS (2003) MicroRNA targets in Drosophila. Genome Biol 5:R1
32. Stark A, Brennecke J, Russell RB, Cohen SM (2003) Identification of Drosophila microRNA targets. PLoS Biol 1:E60
33. Gesellchen V, Broutros M (2004) Managing the genome: microRNAs in Drosophila. Differentiation 72:74-84.
34. Biemar F, Zinzen R, Ronshaugen M, Sementchenko V, Manak JR, Levine MS (2005) Spatial regulation of microRNA gene expression in the Drosophila embryo. Proc Natl Acad Sci U S A 102:15907-15911.
35. Aboobaker AA, Tomancak P, Patel N, Rubin GM, Lai EC (2005) Drosophila microRNAs exhibit diverse spatial expression patterns during embryonic development. Proc Natl Acad Sci U S A 102:18017-18022.
36. Bentwich I (2005) Prediction and validation of microRNAs and their targets. FEBS Lett 579:5904-5910.
37. Wienholds E, Plasterk RHA (2005) MicroRNA function in animal development. FEBS Lett 579:5911-5922.
38. Robins H, Li Y, Padgett RW (2005) Incorporating structure to predict microRNA targets. Proc Natl Acad Sci U S A 102:4006-4009.
39. Lai EC, Tam B, Rubin GM (2005) Pervasive regulation of Drosophila Notch target genes by Gy-box-, Brd-box-, and K-box-class microRNAs. Genes Dev 19:1067-1080.
40. Bartel DP (2009) MicroRNAs: target recognition and regulatory functions. Cell 136:215-233.
41. Carthew RW, Sontheimer EJ (2009) Origins and mechanisms of miRNAs and siRNAs. Cell 136:642-655.
42. Driever W, Nusselein-Volhard C (1989) The bicoid protein is a positive regulator of hunchback transcription in the early Drosophila embryo. Nature 337:138-143.
43. Driever W, Thoma G, Nusselein-Volhard C (1989) Determination of spatial domains of zygotic gene expression in the Drosophila embryo by the affinity of binding sites for the bicoid morphogen. Nature 340:363-367.
44. Struhl G, Struhl K, Macdonald PM (1989) The gradient morphogen bicoid is a concentration-dependent transcriptional activator. Cell 57:1259-1273.
45. Hanes SD, Brent R (1991) A genetic model for interaction of the homeodomain recognition helix with DNA. Science 251:427-430.
46. St Johnston D, Nusselein-Volhard C (1992) The origin of pattern and polarity in the Drosophila embryo. Cell 68:201-219.
47. Small S, Blair R, Levine M (1992) Regulation of even-skipped stripe 2 in the Drosophila embryo. EMBO J 11:4047-4057.
48. Burz DS, Rivera-Pomar R, Jackle H, Hanes SD (1998) Cooperative DNA-binding by Bicoid provides a mechanism for threshold-dependent gene activation in the Drosophila embryo. EMBO J 17:5998-5999.
49. Crauk O, Dostatni N (2005) Bicoid determines sharp and precise target gene expression in the Drosophila embryo. Curr Biol 15:1888-1898.
50. Xie X, Lu J, Kulbokas EJ, Golub TR, Mootha V, Lindblad-Toh K, Lander ES, Lellis M (2005) Systematic discovery of regulatory motifs in human promoters and 3' UTRs by comparison of several mammals. Nature 434:338-345.
51. Hobert O (2004) Common logic of transcription factor and microRNA action. Trends Biochem Sci 29:462-468.
52. Helden J (2003) Regulatory sequence analysis tools. Nucleic Acids Res 31:3593-3596.
53. Bergman CM, Carlson JW, Celniker SE (2005) Drosophila DNase I footprint database: a systematic genome annotation of transcription factor binding sites in the fruit fly, Drosophila melanogaster. Bioinfomatics 21:1747-1749.