Intrinsically radioactive [64Cu]CuInS/ZnS quantum dots for pet and optical imaging: Improved radiochemical stability and controllable cerenkov luminescence

ACS Nano

Volumn 9, Issue 1, 2015, Pages 488-495

  Guo, Weisheng ^a,b   Sun, Xiaolian ^b   Jacobson, Orit ^b   Yan, Xuefeng ^b   Min, Kyunghyun ^b   Srivatsan, Avinash ^b   Niu, Gang ^b   Kiesewetter, Dale O ^b   Chang, Jin ^a   Chen, Xiaoyuan ^b  

^a TIANJIN UNIVERSITY   (China)

^b NATIONAL INSTITUTE OF BIOMEDICAL IMAGING AND BIOENGINEERING   (United States)

Author keywords

CRET; CuInS ZnS; dual modality imaging; PET imaging; quantum dots

Indexed keywords

CHELATION; ENERGY TRANSFER; LIGHT SOURCES; LUMINESCENCE; NANOCRYSTALS; POSITRON EMISSION TOMOGRAPHY; POSITRONS; RADIOACTIVITY; RADIOISOTOPES;

CRET; CUINS/ZNS; DUAL-MODALITY IMAGING; PET IMAGING; POSITRON EMISSION TOMOGRAPHY (PET); POSITRON-EMITTING RADIOISOTOPES; RADIOACTIVITY CONCENTRATION; RADIOCHEMICAL STABILITY;

SEMICONDUCTOR QUANTUM DOTS;

COPPER; INDIUM; QUANTUM DOT; RADIOPHARMACEUTICAL AGENT; SULFIDE; ZINC DERIVATIVE; ZINC SULFIDE;

ANIMAL; CELL TRANSFORMATION; CHEMISTRY; DRUG STABILITY; FLUORESCENCE IMAGING; GLIOBLASTOMA; HUMAN; LUMINESCENCE; MOUSE; PATHOLOGY; POSITRON EMISSION TOMOGRAPHY; PROCEDURES; RADIOCHEMISTRY; SCINTISCANNING; TISSUE DISTRIBUTION; TUMOR CELL LINE;

ANIMALS; CELL LINE, TUMOR; CELL TRANSFORMATION, NEOPLASTIC; COPPER; COPPER RADIOISOTOPES; DRUG STABILITY; GLIOBLASTOMA; HUMANS; INDIUM; LUMINESCENCE; MICE; OPTICAL IMAGING; POSITRON-EMISSION TOMOGRAPHY; QUANTUM DOTS; RADIOCHEMISTRY; RADIOPHARMACEUTICALS; SULFIDES; TISSUE DISTRIBUTION; ZINC COMPOUNDS;

EID: 84921803928     PISSN: 19360851     EISSN: 1936086X     Source Type: Journal    
DOI: 10.1021/nn505660r     Document Type: Article

References (37)

1. Louie, A. Multimodality Imaging probes: Design and Challenges Chem. Rev. 2010, 110, 3146-3195
2. Cheon, J.; Lee, J.-H. Synergistically Integrated Nanoparticles as Multimodal Probes for Nanobiotechnology Acc. Chem. Res. 2008, 41, 1630-1640
3. Nguyen, Q. T.; Tsien, R. Y. Fluorescence-Guided Surgery with Live Molecular Navigation-A New Cutting Edge Nat. Rev. Cancer 2013, 13, 653-662
4. So, M.-K.; Xu, C.; Loening, A. M.; Gambhir, S. S.; Rao, J. Self-Illuminating Quantum Dot Conjugates for in Vivo Imaging Nat. Biotechnol. 2006, 24, 339-343
5. Cai, W.; Chen, X. Multimodality Molecular Imaging of Tumor Angiogenesis J. Nucl. Med. 2008, 49, 113S-128S
6. Ametamey, S. M.; Honer, M.; Schubiger, P. A. Molecular Imaging with PET Chem. Rev. 2008, 108, 1501-1516
7. Lucignani, G. Čerenkov Radioactive Optical Imaging: A Promising New Strategy Eur. J. Nucl. Med. Mol. Imaging 2011, 38, 592-595
8. Thorek, D. L.; Robertson, R.; Bacchus, W. A.; Hahn, J.; Rothberg, J.; Beattie, B. J.; Grimm, J. Cerenkov Imaging-A New Modality for Molecular Imaging Am. J. Nucl. Med. Mol. Imaging 2012, 2, 163-173
9. Dothager, R. S.; Goiffon, R. J.; Jackson, E.; Harpstrite, S.; Piwnica-Worms, D. Cerenkov Radiation Energy Transfer (CRET) Imaging: A Novel Method for Optical Imaging of PET Isotopes in Biological Systems PLoS One 2010, 5, e13300
10. Xu, Y.; Liu, H.; Cheng, Z. Harnessing the Power of Radionuclides for Optical Imaging: Cerenkov Luminescence Imaging J. Nucl. Med. 2011, 52, 2009-2018
11. Bernhard, Y.; Collin, B.; Decréau, R. A. Inter/Intramolecular Cherenkov Radiation Energy Transfer (CRET) from a Fluorophore with a Built-In Radionuclide Chem. Commun. 2014, 50, 6711-6713
12. Liu, H.; Zhang, X.; Xing, B.; Han, P.; Gambhir, S. S.; Cheng, Z. Radiation-Luminescence-Excited Quantum Dots for in Vivo Multiplexed Optical Imaging Small 2010, 6, 1087-1091
13. Wang, Y.; Liu, Y.; Luehmann, H.; Xia, X.; Wan, D.; Cutler, C.; Xia, Y. Radioluminescent Gold Nanocages with Controlled Radioactivity for Real-Time in Vivo Imaging Nano Lett. 2013, 13, 581-585
14. Zhou, C.; Hao, G.; Thomas, P.; Liu, J.; Yu, M.; Sun, S.; Öz, O. K.; Sun, X.; Zheng, J. Near-Infrared Emitting Radioactive Gold Nanoparticles with Molecular Pharmacokinetics Angew. Chem., Int. Ed. 2012, 124, 10265-10269
15. Zhao, Y.; Sultan, D.; Detering, L.; Cho, S.; Sun, G.; Pierce, R.; Wooley, K. L.; Liu, Y. Copper-64-Alloyed Gold Nanoparticles for Cancer Imaging: Improved Radiolabel Stability and Diagnostic Accuracy Angew. Chem., Int. Ed. 2014, 53, 156-159
16. 64Cu Integrated Au Nanomaterials for Positron Emission Tomography Imaging Guided Photothermal Cancer Therapy ACS Nano 2014, 8, 8438-8446
17. 3+-Doped Rare-Earth Microparticles PLoS One 2013, 8, e77926
18. 64Cu-Doped CdSe/ZnS Nanocrystals for In Vivo Tumor Imaging J. Am. Chem. Soc. 2014, 136, 1706-1709
19. Yong, K.-T. Quantum Dots for Biophotonics Theranostics 2012, 2, 629-630
20. Michalet, X.; Pinaud, F. F.; Bentolila, L. A.; Tsay, J. M.; Doose, S.; Li, J. J.; Sundaresan, G.; Wu, A. M.; Gambhir, S. S.; Weiss, S. Quantum Dots for Live Cells, in Vivo Imaging, and Diagnostics Science 2005, 307, 538-544
21. Sarko, D.; Eisenhut, M.; Haberkorn, U.; Mier, W. Bifunctional Chelators in the Design and Application of Radiopharmaceuticals for Oncological Diseases Curr. Med. Chem. 2012, 19, 2667-2688
22. Wadas, T. J.; Wong, E. H.; Weisman, G. R.; Anderson, C. J. Coordinating Radiometals of Copper, Gallium, Indium, Yttrium, and Zirconium for PET and SPECT Imaging of Disease Chem. Rev. 2010, 110, 2858-2902
23. Liu, Y.; Welch, M. J. Nanoparticles Labeled with Positron Emitting Nnuclides: Advantages, Methods, and Applications Bioconjugate Chem. 2012, 23, 671-682
24. 64Cu: Implications for Molecular Imaging of Tumor Characteristics with Copper-Based PET Tracers Nucl. Med. Biol. 2013, 40, 345-350
25. Guo, W.; Chen, N.; Tu, Y.; Dong, C.; Zhang, B.; Hu, C.; Chang, J. Synthesis of Zn-Cu-In-S/ZnS Core/Shell Quantum Dots with Inhibited Blue-Shift Photoluminescence and Applications for Tumor Targeted Bioimaging Theranostics 2013, 3, 99-108
26. Xie, R.; Rutherford, M.; Peng, X. Formation of High-Quality I-III-VI Semiconductor Nanocrystals by Tuning Relative Reactivity of Cationic Precursors J. Am. Chem. Soc. 2009, 131, 5691-5697
27. Chen, Y.; Li, S.; Huang, L.; Pan, D. Green and Facile Synthesis of Water-Soluble Cu-In-S/ZnS Core/Shell Quantum Dots Inorg. Chem. 2013, 52, 7819-7821
28. Chen, Y.; Li, S.; Huang, L.; Pan, D. Low-Cost and Gram-Scale Synthesis of Water-Soluble Cu-In-S/ZnS Core/Shell Quantum Dots in an Electric Pressure Cooker Nanoscale 2014, 6, 1295-1298
29. Wang, Y.; Liu, Y.; Luehmann, H.; Xia, X.; Brown, P.; Jarreau, C.; Welch, M.; Xia, Y. Evaluating the Pharmacokinetics and in Vivo Cancer Targeting Capability of Au Nanocages by Positron Emission Tomography Imaging ACS Nano 2012, 6, 5880-5888
30. Rempel, S.; Podkorytova, A.; Rempel, A. Concentration Quenching of Fluorescence of Colloid Quantum Dots of Cadmium Sulfide Phys. Solid State 2014, 56, 568-571
31. Willard, D. M.; Carillo, L. L.; Jung, J.; Van Orden, A. CdSe-ZnS Quantum Dots as Resonance Energy Transfer Donors in a Model Protein-Protein Binding Assay Nano Lett. 2001, 1, 469-474
32. Gao, X.; Cui, Y.; Levenson, R. M.; Chung, L. W.; Nie, S. In Vivo Cancer Targeting and Imaging with Semiconductor Quantum Dots Nat. Biotechnol. 2004, 22, 969-976
33. Liu, J.; Yu, M.; Ning, X.; Zhou, C.; Yang, S.; Zheng, J. PEGylation and Zwitterionization: Pros and Cons in the Renal Clearance and Tumor Targeting of Near-IR-Emitting Gold Nanoparticles Angew. Chem., Int. Ed. 2013, 125, 12804-12808
34. Choi, H. S.; Liu, W.; Misra, P.; Tanaka, E.; Zimmer, J. P.; Ipe, B. I.; Bawendi, M. G.; Frangioni, J. V. Renal Clearance of Quantum Dots Nat. Biotechnol. 2007, 25, 1165-1170
35. 2 J. Nucl. Med. 2006, 47, 1649-1652
36. 64Cu in Disulfiram Treatment for Aberrant Copper Biodistribution in Menkes Disease Mouse Model J. Nucl. Med. 2014, 55, 845-851
37. Jacobson, O.; Weiss, I. D.; Szajek, L. P.; Niu, G.; Ma, Y.; Kiesewetter, D. O.; Farber, J. M.; Chen, X. PET Imaging of CXCR4 Using Copper-64 Labeled Peptide Antagonist Theranostics 2011, 1, 251-262