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Volumn 10, Issue 11, 2014, Pages 3241-3250

Depletion of tumor-associated macrophages enhances the anti-tumor immunity induced by a toll-like receptor agonist-conjugated peptide

Author keywords

Cyclooxygenase; IL10; Immunotherapy; Macrophage; Peptide; Toll like receptor

Indexed keywords

ANTINEOPLASTIC AGENT; GAMMA INTERFERON; PAM2IDG PEPTIDE; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 6; UNCLASSIFIED DRUG; BLOCKING ANTIBODY; CLODRONIC ACID; CYCLOOXYGENASE 2 INHIBITOR; INTERLEUKIN 10 RECEPTOR; LIPOPEPTIDE; PALMITIC ACID; PROTEIN E7; TLR2 PROTEIN, MOUSE; TLR6 PROTEIN, MOUSE;

EID: 84921753458     PISSN: 21645515     EISSN: 2164554X     Source Type: Journal    
DOI: 10.4161/hv.29275     Document Type: Article
Times cited : (23)

References (48)
  • 2
    • 33845905779 scopus 로고    scopus 로고
    • The natural history of cervical HPV infection: Unresolved issues
    • PMID:17186016
    • Woodman CB, Collins SI, Young LS. The natural history of cervical HPV infection: unresolved issues. Nat Rev Cancer 2007; 7:11-22; PMID:17186016; http://dx.doi.org/10.1038/nrc2050
    • (2007) Nat Rev Cancer , vol.7 , pp. 11-22
    • Woodman, C.B.1    Collins, S.I.2    Young, L.S.3
  • 3
    • 33645211201 scopus 로고    scopus 로고
    • Human papillomaviruses: Basic mechanisms of pathogenesis and oncogenicity
    • PMID:16287204
    • Hebner CM, Laimins LA. Human papillomaviruses: basic mechanisms of pathogenesis and oncogenicity. Rev Med Virol 2006; 16:83-97; PMID:16287204; http://dx.doi.org/10.1002/rmv.488
    • (2006) Rev Med Virol , vol.16 , pp. 83-97
    • Hebner, C.M.1    Laimins, L.A.2
  • 4
    • 42149123438 scopus 로고    scopus 로고
    • Therapeutic human papillomavirus vaccines: Current clinical trials and future directions
    • PMID:18352847
    • Hung CF, Ma B, Monie A, Tsen SW, Wu TC. Therapeutic human papillomavirus vaccines: current clinical trials and future directions. Expert Opin Biol Ther 2008; 8:421-39; PMID:18352847; http://dx.doi.org/10.1517/14712598.8.4.421
    • (2008) Expert Opin Biol Ther , vol.8 , pp. 421-439
    • Hung, C.F.1    Ma, B.2    Monie, A.3    Tsen, S.W.4    Wu, T.C.5
  • 7
    • 0036644556 scopus 로고    scopus 로고
    • Established human papillomavirus type 16-expressing tumors are effectively eradicated following vaccination with long peptides
    • PMID:12077264
    • Zwaveling S, Ferreira Mota SC, Nouta J, Johnson M, Lipford GB, Offringa R, van der Burg SH, Melief CJ. Established human papillomavirus type 16-expressing tumors are effectively eradicated following vaccination with long peptides. J Immunol 2002; 169:350-8; PMID:12077264; http://dx.doi.org/10.4049/jimmunol.169.1.350
    • (2002) J Immunol , vol.169 , pp. 350-358
    • Zwaveling, S.1    Ferreira Mota, S.C.2    Nouta, J.3    Johnson, M.4    Lipford, G.B.5    Offringa, R.6    Van Der Burg, S.H.7    Melief, C.J.8
  • 9
    • 0033738890 scopus 로고    scopus 로고
    • Endocytosis of an HIV-derived lipopeptide into human dendritic cells followed by class I-restricted CD8(+) T lymphocyte activation
    • PMID:11093141
    • Andrieu M, Loing E, Desoutter JF, Connan F, Choppin J, Gras-Masse H, Hanau D, Dautry-Varsat A, Guillet JG, Hosmalin A. Endocytosis of an HIV-derived lipopeptide into human dendritic cells followed by class I-restricted CD8(+) T lymphocyte activation. Eur J Immunol 2000; 30:3256-65; PMID:11093141; http://dx.doi.org/10.1002/1521-4141(200011)30:11≤3256::AID-IMMU3256≤3.0.CO;2-H
    • (2000) Eur J Immunol , vol.30 , pp. 3256-3265
    • Andrieu, M.1    Loing, E.2    Desoutter, J.F.3    Connan, F.4    Choppin, J.5    Gras-Masse, H.6    Hanau, D.7    Dautry-Varsat, A.8    Guillet, J.G.9    Hosmalin, A.10
  • 10
  • 11
    • 34247588705 scopus 로고    scopus 로고
    • Cytotoxic T lymphocyte response induced by an improved synthetic lipopeptide vaccine against cervical cancer
    • PMID:17439726
    • Xu DH, Zhou CH, Xia YP, Qiu ZY, Wu YZ, Jia ZC, Zhou W. Cytotoxic T lymphocyte response induced by an improved synthetic lipopeptide vaccine against cervical cancer. Acta Pharmacol Sin 2007; 28:695-702; PMID:17439726; http://dx.doi.org/10.1111/j.1745-7254.2007.00538.x
    • (2007) Acta Pharmacol Sin , vol.28 , pp. 695-702
    • Xu, D.H.1    Zhou, C.H.2    Xia, Y.P.3    Qiu, Z.Y.4    Wu, Y.Z.5    Jia, Z.C.6    Zhou, W.7
  • 12
    • 42749095859 scopus 로고    scopus 로고
    • Branched and linear lipopeptide vaccines have different effects on primary CD4+ and CD8+ T-cell activation but induce similar tumor-protective memory CD8+ T-cell responses
    • PMID:18420312
    • Baz A, Buttigieg K, Zeng W, Rizkalla M, Jackson DC, Groves P, Kelso A. Branched and linear lipopeptide vaccines have different effects on primary CD4+ and CD8+ T-cell activation but induce similar tumor-protective memory CD8+ T-cell responses. Vaccine 2008; 26:2570-9; PMID:18420312; http://dx.doi.org/10.1016/j.vaccine.2008.03.022
    • (2008) Vaccine , vol.26 , pp. 2570-2579
    • Baz, A.1    Buttigieg, K.2    Zeng, W.3    Rizkalla, M.4    Jackson, D.C.5    Groves, P.6    Kelso, A.7
  • 13
    • 0037229333 scopus 로고    scopus 로고
    • Two human immunodeficiency virus vaccinal lipopeptides follow different crosspresentation pathways in human dendritic cells
    • PMID:12502869
    • Andrieu M, Desoutter JF, Loing E, Gaston J, Hanau D, Guillet JG, Hosmalin A. Two human immunodeficiency virus vaccinal lipopeptides follow different crosspresentation pathways in human dendritic cells. J Virol 2003; 77:1564-70; PMID:12502869; http://dx.doi.org/10.1128/JVI.77.2.1564-1570.2003
    • (2003) J Virol , vol.77 , pp. 1564-1570
    • Andrieu, M.1    Desoutter, J.F.2    Loing, E.3    Gaston, J.4    Hanau, D.5    Guillet, J.G.6    Hosmalin, A.7
  • 14
    • 79961077781 scopus 로고    scopus 로고
    • Presentation of lipopeptide by dendritic cells induces anti-tumor responses via an endocytosis-independent pathway in vivo
    • PMID:21521754
    • Song YC, Chou AH, Homhuan A, Huang MH, Chiang SK, Shen KY, Chuang PW, Leng CH, Tao MH, Chong P, et al. Presentation of lipopeptide by dendritic cells induces anti-tumor responses via an endocytosis-independent pathway in vivo. J Leukoc Biol 2011; 90:323-32; PMID:21521754; http://dx.doi.org/10.1189/jlb.0111046
    • (2011) J Leukoc Biol , vol.90 , pp. 323-332
    • Song, Y.C.1    Chou, A.H.2    Homhuan, A.3    Huang, M.H.4    Chiang, S.K.5    Shen, K.Y.6    Chuang, P.W.7    Leng, C.H.8    Tao, M.H.9    Chong, P.10
  • 15
    • 33845197463 scopus 로고    scopus 로고
    • Comparison of lipopeptide-based immunocontraceptive vaccines containing different lipid groups
    • PMID:17055123
    • Chua BY, Zeng W, Lau YF, Jackson DC. Comparison of lipopeptide-based immunocontraceptive vaccines containing different lipid groups. Vaccine 2007; 25:92-101; PMID:17055123; http://dx.doi.org/10.1016/j. vaccine.2006.07.012
    • (2007) Vaccine , vol.25 , pp. 92-101
    • Chua, B.Y.1    Zeng, W.2    Lau, Y.F.3    Jackson, D.C.4
  • 17
    • 79953875922 scopus 로고    scopus 로고
    • A modular approach to assembly of totally synthetic self-adjuvanting lipopeptide-based vaccines allows conformational epitope building
    • PMID:21321114
    • Zeng W, Horrocks KJ, Robevska G, Wong CY, Azzopardi K, Tauschek M, Robins-Browne RM, Jackson DC. A modular approach to assembly of totally synthetic self-adjuvanting lipopeptide-based vaccines allows conformational epitope building. J Biol Chem 2011; 286:12944-51; PMID:21321114; http://dx.doi.org/10.1074/jbc.M111.227744
    • (2011) J Biol Chem , vol.286 , pp. 12944-12951
    • Zeng, W.1    Horrocks, K.J.2    Robevska, G.3    Wong, C.Y.4    Azzopardi, K.5    Tauschek, M.6    Robins-Browne, R.M.7    Jackson, D.C.8
  • 19
    • 0036295173 scopus 로고    scopus 로고
    • Lipopeptide vaccines-yesterday, today, and tomorrow
    • PMID:12127354
    • BenMohamed L, Wechsler SL, Nesburn AB. Lipopeptide vaccines-yesterday, today, and tomorrow. Lancet Infect Dis 2002; 2:425-31; PMID:12127354; http://dx.doi.org/10.1016/S1473-3099(02)00318-3
    • (2002) Lancet Infect Dis , vol.2 , pp. 425-431
    • BenMohamed, L.1    Wechsler, S.L.2    Nesburn, A.B.3
  • 20
    • 34248172324 scopus 로고    scopus 로고
    • Altered macrophage differentiation and immune dysfunction in tumor development
    • PMID:17476345
    • Sica A, Bronte V. Altered macrophage differentiation and immune dysfunction in tumor development. J Clin Invest 2007; 117:1155-66; PMID:17476345; http://dx.doi.org/10.1172/JCI31422
    • (2007) J Clin Invest , vol.117 , pp. 1155-1166
    • Sica, A.1    Bronte, V.2
  • 21
    • 0036839143 scopus 로고    scopus 로고
    • Macrophage polarization: Tumor-associated macrophages as a paradigm for polarized M2 mononuclear phagocytes
    • PMID:12401408
    • Mantovani A, Sozzani S, Locati M, Allavena P, Sica A. Macrophage polarization: tumor-associated macrophages as a paradigm for polarized M2 mononuclear phagocytes. Trends Immunol 2002; 23:549-55; PMID:12401408; http://dx.doi.org/10.1016/S1471-4906(02)02302-5
    • (2002) Trends Immunol , vol.23 , pp. 549-555
    • Mantovani, A.1    Sozzani, S.2    Locati, M.3    Allavena, P.4    Sica, A.5
  • 22
    • 84863691003 scopus 로고    scopus 로고
    • Macrophages in tumor microenvironments and the progression of tumors
    • PMID:22778768
    • Hao NB, Lü MH, Fan YH, Cao YL, Zhang ZR, Yang SM. Macrophages in tumor microenvironments and the progression of tumors. Clin Dev Immunol 2012; 2012:948098; PMID:22778768; http://dx.doi.org/10.1155/2012/948098
    • (2012) Clin Dev Immunol , vol.2012 , pp. 948098
    • Hao, N.B.1    Lü, M.H.2    Fan, Y.H.3    Cao, Y.L.4    Zhang, Z.R.5    Yang, S.M.6
  • 23
    • 80053211234 scopus 로고    scopus 로고
    • New approaches to immunotherapy for HPV associated cancers
    • PMID:24212964
    • Bergot AS, Kassianos A, Frazer IH, Mittal D. New Approaches to Immunotherapy for HPV Associated Cancers. Cancers (Basel) 2011; 3:3461-95; PMID:24212964; http://dx.doi.org/10.3390/cancers3033461
    • (2011) Cancers (Basel) , vol.3 , pp. 3461-3495
    • Bergot, A.S.1    Kassianos, A.2    Frazer, I.H.3    Mittal, D.4
  • 24
    • 84855608187 scopus 로고    scopus 로고
    • Molecular mechanism and potential targets for blocking HPV-induced lesion development
    • PMID:22220169
    • Guzmán-Olea E, Bermúdez-Morales VH, Peralta-Zaragoza O, Torres-Poveda K, Madrid-Marina V. Molecular Mechanism and Potential Targets for Blocking HPV-Induced Lesion Development. J Oncol 2012; 2012:278312; PMID:22220169; http://dx.doi.org/10.1155/2012/278312
    • (2012) J Oncol , vol.2012 , pp. 278312
    • Guzmán-Olea, E.1    Bermúdez-Morales, V.H.2    Peralta-Zaragoza, O.3    Torres-Poveda, K.4    Madrid-Marina, V.5
  • 25
    • 67650391196 scopus 로고    scopus 로고
    • HPV16 tumor associated macrophages suppress antitumor T cell responses
    • PMID:19549768
    • Lepique AP, Daghastanli KR, Cuccovia IM, Villa LL. HPV16 tumor associated macrophages suppress antitumor T cell responses. Clin Cancer Res 2009; 15:4391-400; PMID:19549768; http://dx.doi.org/10.1158/1078-0432.CCR-09-0489
    • (2009) Clin Cancer Res , vol.15 , pp. 4391-4400
    • Lepique, A.P.1    Daghastanli, K.R.2    Cuccovia, I.M.3    Villa, L.L.4
  • 26
    • 84855817522 scopus 로고    scopus 로고
    • Immunology in the clinic review series; focus on cancer: Tumour-associated macrophages: Undisputed stars of the inflammatory tumour microenvironment
    • PMID:22235995
    • Allavena P, Mantovani A. Immunology in the clinic review series; focus on cancer: tumour-associated macrophages: undisputed stars of the inflammatory tumour microenvironment. Clin Exp Immunol 2012; 167:195-205; PMID:22235995; http://dx.doi.org/10.1111/j.1365-2249.2011.04515.x
    • (2012) Clin Exp Immunol , vol.167 , pp. 195-205
    • Allavena, P.1    Mantovani, A.2
  • 28
    • 84869092549 scopus 로고    scopus 로고
    • The multi-faceted roles of prostaglandin E2 in cancer-infiltrating mononuclear phagocyte biology
    • PMID:22727331
    • Sha W, Brüne B, Weigert A. The multi-faceted roles of prostaglandin E2 in cancer-infiltrating mononuclear phagocyte biology. Immunobiology 2012; 217:1225-32; PMID:22727331; http://dx.doi.org/10.1016/j.imbio.2012.05.001
    • (2012) Immunobiology , vol.217 , pp. 1225-1232
    • Sha, W.1    Brüne, B.2    Weigert, A.3
  • 30
    • 77951102185 scopus 로고    scopus 로고
    • Structure-activity relationships in toll-like receptor-2 agonistic diacylthioglycerol lipopeptides
    • PMID:20302301
    • Wu W, Li R, Malladi SS, Warshakoon HJ, Kimbrell MR, Amolins MW, Ukani R, Datta A, David SA. Structure-activity relationships in toll-like receptor-2 agonistic diacylthioglycerol lipopeptides. J Med Chem 2010; 53:3198-213; PMID:20302301; http://dx.doi.org/10.1021/jm901839g
    • (2010) J Med Chem , vol.53 , pp. 3198-3213
    • Wu, W.1    Li, R.2    Malladi, S.S.3    Warshakoon, H.J.4    Kimbrell, M.R.5    Amolins, M.W.6    Ukani, R.7    Datta, A.8    David, S.A.9
  • 31
    • 83455203338 scopus 로고    scopus 로고
    • Identification and manipulation of tumor associated macrophages in human cancers
    • PMID:22176642
    • Heusinkveld M, van der Burg SH. Identification and manipulation of tumor associated macrophages in human cancers. J Transl Med 2011; 9:216; PMID:22176642; http://dx.doi.org/10.1186/1479-5876-9-216
    • (2011) J Transl Med , vol.9 , pp. 216
    • Heusinkveld, M.1    Van Der Burg, S.H.2
  • 32
    • 84899535581 scopus 로고    scopus 로고
    • Toll-like receptor 9 agonist enhances anti-tumor immunity and inhibits tumor-associated immunosuppressive cells numbers in a mouse cervical cancer model following recombinant lipoprotein therapy
    • PMID:24642245
    • Chang LS, Leng CH, Yeh YC, Wu CC, Chen HW, Huang HM, Liu SJ. Toll-like receptor 9 agonist enhances anti-tumor immunity and inhibits tumor-associated immunosuppressive cells numbers in a mouse cervical cancer model following recombinant lipoprotein therapy. Mol Cancer 2014; 13:60; PMID:24642245; http://dx.doi.org/10.1186/1476-4598-13-60
    • (2014) Mol Cancer , vol.13 , pp. 60
    • Chang, L.S.1    Leng, C.H.2    Yeh, Y.C.3    Wu, C.C.4    Chen, H.W.5    Huang, H.M.6    Liu, S.J.7
  • 33
    • 84863998596 scopus 로고    scopus 로고
    • Recombinant lipidated HPV E7 induces a Th-1-biased immune response and protective immunity against cervical cancer in a mouse model
    • PMID:22815882
    • Huang CY, Chen JJ, Shen KY, Chang LS, Yeh YC, Chen IH, Chong P, Liu SJ, Leng CH. Recombinant lipidated HPV E7 induces a Th-1-biased immune response and protective immunity against cervical cancer in a mouse model. PLoS One 2012; 7:e40970; PMID:22815882; http://dx.doi.org/10.1371/journal.pone.0040970
    • (2012) PLoS One , vol.7
    • Huang, C.Y.1    Chen, J.J.2    Shen, K.Y.3    Chang, L.S.4    Yeh, Y.C.5    Chen, I.H.6    Chong, P.7    Liu, S.J.8    Leng, C.H.9
  • 34
    • 49749110778 scopus 로고    scopus 로고
    • A self-adjuvanting lipopep-tide-based vaccine candidate for the treatment of hepatitis C virus infection
    • PMID:18455278
    • Chua BY, Eriksson EM, Brown LE, Zeng W, Gowans EJ, Torresi J, Jackson DC. A self-adjuvanting lipopep-tide-based vaccine candidate for the treatment of hepatitis C virus infection. Vaccine 2008; 26:4866-75; PMID:18455278; http://dx.doi.org/10.1016/j.vaccine.2008.03.032
    • (2008) Vaccine , vol.26 , pp. 4866-4875
    • Chua, B.Y.1    Eriksson, E.M.2    Brown, L.E.3    Zeng, W.4    Gowans, E.J.5    Torresi, J.6    Jackson, D.C.7
  • 35
    • 33745817772 scopus 로고    scopus 로고
    • Heat shock protein 60 enhances CD4+ CD25+ regulatory T cell function via innate TLR2 signaling
    • PMID:16767222
    • Zanin-Zhorov A, Cahalon L, Tal G, Margalit R, Lider O, Cohen IR. Heat shock protein 60 enhances CD4+ CD25+ regulatory T cell function via innate TLR2 signaling. J Clin Invest 2006; 116:2022-32; PMID:16767222; http://dx.doi.org/10.1172/JCI28423
    • (2006) J Clin Invest , vol.116 , pp. 2022-2032
    • Zanin-Zhorov, A.1    Cahalon, L.2    Tal, G.3    Margalit, R.4    Lider, O.5    Cohen, I.R.6
  • 36
    • 84861787202 scopus 로고    scopus 로고
    • Dendritic cell-activating vaccine adjuvants differ in the ability to elicit antitumor immunity due to an adjuvant-specific induction of immunosuppressive cells
    • PMID:22510348
    • Dang Y, Wagner WM, Gad E, Rastetter L, Berger CM, Holt GE, Disis ML. Dendritic cell-activating vaccine adjuvants differ in the ability to elicit antitumor immunity due to an adjuvant-specific induction of immunosuppressive cells. Clin Cancer Res 2012; 18:3122-31; PMID:22510348; http://dx.doi.org/10.1158/1078-0432.CCR-12-0113
    • (2012) Clin Cancer Res , vol.18 , pp. 3122-3131
    • Dang, Y.1    Wagner, W.M.2    Gad, E.3    Rastetter, L.4    Berger, C.M.5    Holt, G.E.6    Disis, M.L.7
  • 37
    • 84856541896 scopus 로고    scopus 로고
    • Interleukin 10 in the tumor microenvironment: A target for anticancer immunotherapy
    • PMID:22139852
    • Sato T, Terai M, Tamura Y, Alexeev V, Mastrangelo MJ, Selvan SR. Interleukin 10 in the tumor microenvironment: a target for anticancer immunotherapy. Immunol Res 2011; 51:170-82; PMID:22139852; http://dx.doi.org/10.1007/s12026-011-8262-6
    • (2011) Immunol Res , vol.51 , pp. 170-182
    • Sato, T.1    Terai, M.2    Tamura, Y.3    Alexeev, V.4    Mastrangelo, M.J.5    Selvan, S.R.6
  • 38
    • 77953069764 scopus 로고    scopus 로고
    • Interleukin-10 production by tumor infiltrating macrophages plays a role in Human Papillomavirus 16 tumor growth
    • PMID:20525400
    • Bolpetti A, Silva JS, Villa LL, Lepique AP. Interleukin-10 production by tumor infiltrating macrophages plays a role in Human Papillomavirus 16 tumor growth. BMC Immunol 2010; 11:27; PMID:20525400; http://dx.doi.org/10.1186/1471-2172-11-27
    • (2010) BMC Immunol , vol.11 , pp. 27
    • Bolpetti, A.1    Silva, J.S.2    Villa, L.L.3    Lepique, A.P.4
  • 39
    • 33745311263 scopus 로고    scopus 로고
    • FOXP3+CD4+CD25+ adaptive regulatory T cells express cyclooxygenase-2 and suppress effector T cells by a prostaglandin E2-dependent mechanism
    • PMID:16785520
    • Mahic M, Yaqub S, Johansson CC, Taskén K, Aandahl EM. FOXP3+CD4+CD25+ adaptive regulatory T cells express cyclooxygenase-2 and suppress effector T cells by a prostaglandin E2-dependent mechanism. J Immunol 2006; 177:246-54; PMID:16785520; http://dx.doi.org/10.4049/jimmunol.177.1.246
    • (2006) J Immunol , vol.177 , pp. 246-254
    • Mahic, M.1    Yaqub, S.2    Johansson, C.C.3    Taskén, K.4    Aandahl, E.M.5
  • 40
    • 84896390675 scopus 로고    scopus 로고
    • Intratumoral COX-2 inhibition enhances GM-CSF immunotherapy against established mouse GL261 brain tumors
    • PMID:24243648
    • Eberstal S, Sandén E, Fritzell S, Darabi A, Visse E, Siesjö P. Intratumoral COX-2 inhibition enhances GM-CSF immunotherapy against established mouse GL261 brain tumors. Int J Cancer 2014; 134:2748-53; PMID:24243648; http://dx.doi.org/10.1002/ijc.28607
    • (2014) Int J Cancer , vol.134 , pp. 2748-2753
    • Eberstal, S.1    Sandén, E.2    Fritzell, S.3    Darabi, A.4    Visse, E.5    Siesjö, P.6
  • 41
    • 0141643249 scopus 로고    scopus 로고
    • Effects of hypoxia on monocyte inflammatory mediator production: Dissociation between changes in cyclooxygenase-2 expression and eicosanoid synthesis
    • PMID:12874281
    • Demasi M, Cleland LG, Cook-Johnson RJ, Caughey GE, James MJ. Effects of hypoxia on monocyte inflammatory mediator production: Dissociation between changes in cyclooxygenase-2 expression and eicosanoid synthesis. J Biol Chem 2003; 278:38607-16; PMID:12874281; http://dx.doi.org/10.1074/jbc.M305944200
    • (2003) J Biol Chem , vol.278 , pp. 38607-38616
    • Demasi, M.1    Cleland, L.G.2    Cook-Johnson, R.J.3    Caughey, G.E.4    James, M.J.5
  • 42
    • 0042847262 scopus 로고    scopus 로고
    • Macrophages of the splenic marginal zone are essential for trapping of blood-borne particulate antigen but dispensable for induction of specific T cell responses
    • PMID:12874200
    • Aichele P, Zinke J, Grode L, Schwendener RA, Kaufmann SH, Seiler P. Macrophages of the splenic marginal zone are essential for trapping of blood-borne particulate antigen but dispensable for induction of specific T cell responses. J Immunol 2003; 171:1148-55; PMID:12874200; http://dx.doi.org/10.4049/jimmunol.171.3.1148
    • (2003) J Immunol , vol.171 , pp. 1148-1155
    • Aichele, P.1    Zinke, J.2    Grode, L.3    Schwendener, R.A.4    Kaufmann, S.H.5    Seiler, P.6
  • 43
    • 32244441218 scopus 로고    scopus 로고
    • Dendritic cells rapidly recruited into epithelial tissues via CCR6/CCL20 are responsible for CD8+ T cell crosspriming in vivo
    • PMID:16473831
    • Le Borgne M, Etchart N, Goubier A, Lira SA, Sirard JC, van Rooijen N, Caux C, Äit-Yahia S, Vicari A, Kaiserlian D, et al. Dendritic cells rapidly recruited into epithelial tissues via CCR6/CCL20 are responsible for CD8+ T cell crosspriming in vivo. Immunity 2006; 24:191-201; PMID:16473831; http://dx.doi.org/10.1016/j.immuni.2006.01.005
    • (2006) Immunity , vol.24 , pp. 191-201
    • Le Borgne, M.1    Etchart, N.2    Goubier, A.3    Lira, S.A.4    Sirard, J.C.5    Van Rooijen, N.6    Caux, C.7    Äit-Yahia, S.8    Vicari, A.9    Kaiserlian, D.10
  • 44
    • 84874368497 scopus 로고    scopus 로고
    • Depletion of phagocytic myeloid cells triggers spontaneous T cell-and NK cell-dependent antitumor activity
    • PMID:23243588
    • Guth AM, Hafeman SD, Dow SW. Depletion of phagocytic myeloid cells triggers spontaneous T cell-and NK cell-dependent antitumor activity. Oncoimmunology 2012; 1:1248-57; PMID:23243588; http://dx.doi.org/10.4161/onci.21317
    • (2012) Oncoimmunology , vol.1 , pp. 1248-1257
    • Guth, A.M.1    Hafeman, S.D.2    Dow, S.W.3
  • 46
    • 77956413907 scopus 로고    scopus 로고
    • T-cell response to human papillomavirus type 58 L1, E6, and E7 peptides in women with cleared infection, cervical intraepithelial neoplasia, or invasive cancer
    • PMID:20668141
    • Chan PK, Liu SJ, Cheung TH, Yeo W, Ngai SM, Cheung JL, Chong P, Man S. T-cell response to human papillomavirus type 58 L1, E6, And E7 peptides in women with cleared infection, cervical intraepithelial neoplasia, or invasive cancer. Clin Vaccine Immunol 2010; 17:1315-21; PMID:20668141; http://dx.doi.org/10.1128/CVI.00105-10
    • (2010) Clin Vaccine Immunol , vol.17 , pp. 1315-1321
    • Chan, P.K.1    Liu, S.J.2    Cheung, T.H.3    Yeo, W.4    Ngai, S.M.5    Cheung, J.L.6    Chong, P.7    Man, S.8
  • 47
    • 79954578372 scopus 로고    scopus 로고
    • T-cell response to human papillomavirus type 52 L1, E6, and E7 peptides in women with transient infection, cervical intraepithelial neoplasia, and invasive cancer
    • PMID:21503915
    • Chan PK, Liu SJ, Cheung JL, Cheung TH, Yeo W, Chong P, Man S. T-cell response to human papillomavirus type 52 L1, E6, and E7 peptides in women with transient infection, cervical intraepithelial neoplasia, and invasive cancer. J Med Virol 2011; 83:1023-30; PMID:21503915; http://dx.doi.org/10.1002/jmv.21889
    • (2011) J Med Virol , vol.83 , pp. 1023-1030
    • Chan, P.K.1    Liu, S.J.2    Cheung, J.L.3    Cheung, T.H.4    Yeo, W.5    Chong, P.6    Man, S.7
  • 48
    • 59649116879 scopus 로고    scopus 로고
    • A novel technology for the production of a heterologous lipoprotein immunogen in high yield has implications for the field of vaccine design
    • PMID:19150476
    • Chen HW, Liu SJ, Liu HH, Kwok Y, Lin CL, Lin LH, Chen MY, Tsai JP, Chang LS, Chiu FF, et al. A novel technology for the production of a heterologous lipoprotein immunogen in high yield has implications for the field of vaccine design. Vaccine 2009; 27:1400-9; PMID:19150476; http://dx.doi.org/10.1016/j.vaccine.2008.12.043
    • (2009) Vaccine , vol.27 , pp. 1400-1409
    • Chen, H.W.1    Liu, S.J.2    Liu, H.H.3    Kwok, Y.4    Lin, C.L.5    Lin, L.H.6    Chen, M.Y.7    Tsai, J.P.8    Chang, L.S.9    Chiu, F.F.10


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