Branched and linear lipopeptide vaccines have different effects on primary CD4+ and CD8+ T-cell activation but induce similar tumor-protective memory CD8+ T-cell responses

Vaccine

Volumn 26, Issue 21, 2008, Pages 2570-2579

  Baz, Adriana ^a   Buttigieg, Kathy ^a   Zeng, Weiguang ^b   Rizkalla, Michael ^b   Jackson, David C ^b   Groves, Penny ^a   Kelso, Anne ^a  

^a QIMR BERGHOFER MEDICAL RESEARCH INSTITUTE   (Australia)

^b UNIVERSITY OF MELBOURNE   (Australia)

Author keywords

CTL; Granzymes; Lipopeptide vaccines; T cell memory; Tumor immunity

Indexed keywords

CANCER VACCINE; EPITOPE; GAMMA INTERFERON; GRANZYME A; GRANZYME B; GRANZYME C; ISOLEUCYLSERYLGLUTAMINYLALANYLVALYLHISTIDYLALANYLALANYLHISTIDYLALANYL GLUTAMYLISOLEUCYLASPARAGINYLGLUTAMYLALANYLGLYCYLARGININE; LIPOPEPTIDE; MESSENGER RNA; OVALBUMIN; PEPTIDE; PERFORIN; SERYLISOLEUCYLISOLEUCYLASPARAGINYLPHENYLALANYLGLUTAMYLLYSYLLEUCINE; TOLL LIKE RECEPTOR 2;

ADOPTIVE TRANSFER; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CANCER CELL CULTURE; CARCINOGENESIS; CD4+ CD8+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CONTROLLED STUDY; CYTOTOXIC T LYMPHOCYTE; FEMALE; GENE EXPRESSION; MEMORY T LYMPHOCYTE; MOUSE; NONHUMAN; PRIORITY JOURNAL; SINGLE DRUG DOSE; T LYMPHOCYTE; T LYMPHOCYTE ACTIVATION; TUMOR;

ANIMALS; CANCER VACCINES; CARRIER PROTEINS; CD4-POSITIVE T-LYMPHOCYTES; CD8-POSITIVE T-LYMPHOCYTES; CYTOTOXICITY TESTS, IMMUNOLOGIC; EPITOPES, T-LYMPHOCYTE; GENE EXPRESSION; GRANZYMES; IMMUNOLOGIC MEMORY; INTERFERON TYPE II; LIPOPROTEINS; LYMPHOCYTE ACTIVATION; MICE; NEOPLASMS; OVALBUMIN; PERFORIN; SURVIVAL ANALYSIS; T-LYMPHOCYTES, CYTOTOXIC; TUMOR CELLS, CULTURED; VACCINES, SUBUNIT;

EID: 42749095859     PISSN: 0264410X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.vaccine.2008.03.022     Document Type: Article

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