Structure-activity relationships in toll-like receptor-2 agonistic diacylthioglycerol lipopeptides

Journal of Medicinal Chemistry

Volumn 53, Issue 8, 2010, Pages 3198-3213

  Wu, Wenyan ^a   Li, Rongti ^a   Malladi, Subbalakshmi S ^a   Warshakoon, Hemamali J ^a   Kimbrell, Matthew R ^a   Amolins, Michael W ^a   Ukani, Rehman ^a   Datta, Apurba ^a   David, Sunil A ^a  

^a UNIVERSITY OF KANSAS   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYSTEINE DERIVATIVE; DIPEPTIDE; GLYCEROL DERIVATIVE; LIPOPEPTIDE; LIPOPROTEIN; SERINE; THIOL DERIVATIVE; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR AGONIST;

ACYLATION; AMINO TERMINAL SEQUENCE; ANIMAL CELL; ARTICLE; DRUG RECEPTOR BINDING; HUMAN; IMMUNOSTIMULATION; INNATE IMMUNITY; MOUSE; NONHUMAN; REPORTER GENE; STEREOCHEMISTRY; STRUCTURE ACTIVITY RELATION;

CELL LINE; CYSTINE; GLYCEROL; HUMANS; LIPOPEPTIDES; NF-KAPPA B; SERINE; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP; SULFIDES; TOLL-LIKE RECEPTOR 2;

EID: 77951102185     PISSN: 00222623     EISSN: 15204804     Source Type: Journal    
DOI: 10.1021/jm901839g     Document Type: Article

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