Outer membrane vesicles alter inflammation and coagulation mediators

Journal of Surgical Research

Volumn 192, Issue 1, 2014, Pages 134-142

  Soult, Michael C ^a   Dobrydneva, Yuliya ^a   Wahab, Kamal H ^a   Britt, L D ^a   Sullivan, Claretta J ^a  

^a EASTERN VIRGINIA MEDICAL SCHOOL   (United States)

Author keywords

Coagulation; Endothelium; Monocyteeplatelet aggregation; Outer membrane vesicles; Sepsis; Thrombomodulin; Tissue factor

Indexed keywords

CELL ADHESION MOLECULE; ENDOTHELIAL LEUKOCYTE ADHESION MOLECULE 1; PADGEM PROTEIN; POLYMYXIN B; THROMBOMODULIN; THROMBOPLASTIN; LIPOPOLYSACCHARIDE; OUTER MEMBRANE PROTEIN; SELE PROTEIN, HUMAN; THBD PROTEIN, HUMAN;

ADULT; ARTICLE; CONTROLLED STUDY; ENDOTHELIUM CELL; HUMAN; HUMAN CELL; INFLAMMATION; MEMBRANE VESICLE; MONOCYTE; OUTER MEMBRANE; PRIORITY JOURNAL; PROTEIN EXPRESSION; SUPERNATANT; THROMBOCYTE ACTIVATION; THROMBOCYTE AGGREGATION; UMBILICAL VEIN ENDOTHELIAL CELL; BLOOD CLOTTING; CYTOPLASM VESICLE; ESCHERICHIA COLI; IMMUNOLOGY; MEMBRANE MICROPARTICLE; METABOLISM; SEPSIS; THROMBOPHILIA;

BACTERIAL OUTER MEMBRANE PROTEINS; BLOOD COAGULATION; CELL-DERIVED MICROPARTICLES; CYTOPLASMIC VESICLES; E-SELECTIN; ESCHERICHIA COLI; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; HUMANS; LIPOPOLYSACCHARIDES; MONOCYTES; P-SELECTIN; PLATELET ACTIVATION; SEPSIS; THROMBOMODULIN; THROMBOPHILIA; THROMBOPLASTIN;

EID: 84921712822     PISSN: 00224804     EISSN: 10958673     Source Type: Journal    
DOI: 10.1016/j.jss.2014.05.007     Document Type: Article

References (47)

1. Angus DC, Linde-Zwirble WT, Lidicker J, et al. Epidemiology of severe sepsis in the United States: analysis of incidence, outcome, and associated costs of care. Crit Care Med 2001;29: 1303.
2. Alberti C, Brun-Buisson C, Goodman SV, et al. Influence of systemic inflammatory response syndrome and sepsis on outcome of critically ill infected patients. Am J Respir Crit Care Med 2003;168:77.
3. Bone RC, Balk RA, Cerra FB, et al. Definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis. The ACCP/SCCM Consensus Conference Committee. American College of Chest Physicians/Society of Critical Care Medicine. Chest 1992;101:1644.
4. Levi M. The coagulant response in sepsis and inflammation. Hamostaseologie 2010;30:10. 14-16.
5. Bateman RM, Sharpe MD, Ellis CG. Bench-to-bedside review: microvascular dysfunction in sepsisehemodynamics, oxygen transport, and nitric oxide. Crit Care 2003;7:359 (London, England).
6. Opal SM, Esmon CT. Bench-to-bedside review: functional relationships between coagulation and the innate immune response and their respective roles in the pathogenesis of sepsis. Crit Care 2003;7:23 (London, England).
7. Cinel I, Opal SM. Molecular biology of inflammation and sepsis: a primer. Crit Care Med 2009;37:291.
8. Cines DB, Pollak ES, Buck CA, et al. Endothelial cells in physiology and in the pathophysiology of vascular disorders. Blood 1998;91:3527.
9. Pinsky MR, Vincent JL, Deviere J, et al. Serum cytokine levels in human septic shock. Relation to multiple-system organ failure and mortality. Chest 1993;103:565.
10. Reinhart K, Bayer O, Brunkhorst F, Meisner M. Markers of endothelial damage in organ dysfunction and sepsis. Crit Care Med 2002;30:S302.
11. Springer TA. Leucocyte adhesion to cells. Scand J Immunol 1990;32:211.
12. Kuzu I, Bicknell R, Fletcher CD, Gatter KC. Expression of adhesion molecules on the endothelium of normal tissue vessels and vascular tumors. Lab Invest 1993; 69:322.
13. Shapiro NI, Schuetz P, Yano K, et al. The association of endothelial cell signaling, severity of illness, and organ dysfunction in sepsis. Crit Care 2010;14:R182 (London, England).
14. Steeber DA, Tang ML, Green NE, et al. Leukocyte entry into sites of inflammation requires overlapping interactions between the L-selectin and ICAM-1 pathways. J Immunol 1999;163:2176.
15. Lee WL, Liles WC. Endothelial activation, dysfunction and permeability during severe infections. Curr Opin Hematol 2011;18:191.
16. Stern DM, Esposito C, Gerlach H, et al. Endothelium and regulation of coagulation. Diabetes Care 1991;14:160.
17. Kasthuri RS, Glover SL, Boles J, Mackman N. Tissue factor and tissue factor pathway inhibitor as key regulators of global hemostasis: measurement of their levels in coagulation assays. Semin Thromb Hemost 2010;36:764.
18. Manly DA, Boles J, Mackman N. Role of tissue factor in venous thrombosis. Annu Rev Physiol 2011;73:515.
19. Weiss DJ, Rashid J. The sepsis-coagulant axis: a review. J Vet Intern Med/Am Coll Vet Intern Med 1998;12:317.
20. Van de Wouwer M, Collen D, Conway EM. Thrombomodulinprotein C-EPCR system: integrated to regulate coagulation and inflammation. Arteriosclerosis Thromb Vasc Biol 2004; 24:1374.
21. Faust SN, Levin M, Harrison OB, et al. Dysfunction of endothelial protein C activation in severe meningococcal sepsis. The New Engl J Med 2001;345:408.
22. Schouten M, Wiersinga WJ, Levi M, van der Poll T. Inflammation, endothelium, and coagulation in sepsis. J Leukoc Biol 2008;83:536.
23. van Hinsbergh VW. Endotheliumerole in regulation of coagulation and inflammation. Semin Immunopathology 2012;34:93.
24. Michelson AD, Barnard MR, Krueger LA, Valeri CR, Furman MI. Circulating monocyte-platelet aggregates are a more sensitive marker of in vivo platelet activation than platelet surface P-selectin: studies in baboons, human coronary intervention, and human acute myocardial infarction. Circulation 2001;104:1533.
25. Blann AD, Nadar SK, Lip GY. The adhesion molecule P-selectin and cardiovascular disease. Eur Heart J 2003;24: 2166.
26. Secor D, Swarbreck S, Ellis CG, Sharpe MD, Tyml K. Ascorbate reduces mouse platelet aggregation and surface P-selectin expression in an ex vivo model of sepsis. Microcirculation 2013;20:502.
27. Michelson AD, Barnard MR, Hechtman HB, et al. In vivo tracking of platelets: circulating degranulated platelets rapidly lose surface P-selectin but continue to circulate and function. Proc Natl Acad Sci U S A 1996;93:11877.
28. Rondina MT, Grissom CK, Men S, et al. Whole blood flow cytometry measurements of in vivo platelet activation in critically-Ill patients are influenced by variability in blood sampling techniques. Thromb Res 2012;129:729.
29. Horstman AL, Kuehn MJ. Enterotoxigenic Escherichia coli secretes active heat-labile enterotoxin via outer membrane vesicles. The J Biol Chem 2000;275:12489.
30. Kuehn MJ, Kesty NC. Bacterial outer membrane vesicles and the host-pathogen interaction. Genes Dev 2005;19:2645.
31. Kadurugamuwa JL, Beveridge TJ. Virulence factors are released from Pseudomonas aeruginosa in association with membrane vesicles during normal growth and exposure to gentamicin: a novel mechanism of enzyme secretion. J Bacteriol 1995;177:3998.
32. Ellis TN, Kuehn MJ. Virulence and immunomodulatory roles of bacterial outer membrane vesicles. Microbiol Mol Biol Rev 2010;74:81.
33. Kulp A, Kuehn MJ. Biological functions and biogenesis of secreted bacterial outer membrane vesicles. Annu Rev Microbiol 2010;64:163.
34. Park KS, Choi KH, Kim YS, et al. Outer membrane vesicles derived from Escherichia coli induce systemic inflammatory response syndrome. PLoS One 2010;5:e11334.
35. Shah B, Sullivan CJ, Lonergan NE, et al. Circulating bacterial membrane vesicles cause sepsis in rats. Shock 2012;37:621.
36. Soult MC, Lonergan NE, Shah B, et al. Outer membrane vesicles from pathogenic bacteria initiate an inflammatory response in human endothelial cells. The J Surg Res 2013; 184:458.
37. Doktycz MJ, Sullivan CJ, Hoyt PR, et al. AFM imaging of bacteria in liquid media immobilized on gelatin coated mica surfaces. Ultramicroscopy 2003;97:209.
38. Barnard MR, Krueger LA, Frelinger AL, 3rd, Furman MI, Michelson AD Whole blood analysis of leukocyte-platelet aggregates. CurrentProtoc cytometry/editorial board, J. Paul Robinson, managing editor. et al. 2003: Chapter 6:Unit 6 15.
39. Wolf P. The nature and significance of platelet products in human plasma. Br J Haematol 1967;13:269.
40. Berckmans RJ, Nieuwland R, Boing AN, et al. Cell-derived microparticles circulate in healthy humans and support low grade thrombin generation. Thromb Haemost 2001;85: 639.
41. Martinez MC, Tesse A, Zobairi F, Andriantsitohaina R. Shed membrane microparticles fromcirculating and vascular cells in regulating vascular function. Am J Physiol Heart Circ Physiol 2005;288:H1004.
42. Leroyer AS, Isobe H, Leseche G, et al. Cellular origins and thrombogenic activity of microparticles isolated from human atherosclerotic plaques. J Am Coll Cardiol 2007; 49:772.
43. Chironi GN, Boulanger CM, Simon A, et al. Endothelial microparticles in diseases. Cell Tissue Res 2009;335:143.
44. Levi M, Keller TT, van Gorp E, ten Cate H. Infection and inflammation and the coagulation system. Cardiovasc Res 2003;60:26.
45. Esmon CT. The interactions between inflammation and coagulation. Br J Haematol 2005;131:417.
46. Amara U, Flierl MA, Rittirsch D, et al. Molecular intercommunication between the complement and coagulation systems. J Immunol 2010;185:5628.
47. Gerritsen ME. Functional heterogeneity of vascular endothelial cells. Biochem Pharmacol 1987;36:2701.