Ascorbate reduces mouse platelet aggregation and surface p-selectin expression in an ex vivo model of sepsis

Microcirculation

Volumn 20, Issue 6, 2013, Pages 502-510

  Secor, Dan ^a,b   Swarbreck, Scott ^a,b   Ellis, Christopher G ^a,b   Sharpe, Michael D ^b   Tyml, Karel ^a,b  

^a LAWSON HEALTH RESEARCH INSTITUTE   (Canada)

^b UNIVERSITY OF WESTERN ONTARIO   (Canada)

Author keywords

Capillary plugging; Nitric oxide; Platelet adhesion; Thrombin; Vitamin C

Indexed keywords

15 HYDROXY 11ALPHA,9ALPHA EPOXYMETHANOPROSTA 5,13 DIENOIC ACID; ASCORBIC ACID; LIPOPOLYSACCHARIDE; PADGEM PROTEIN; THROMBIN; TUMOR NECROSIS FACTOR ALPHA; ANTIOXIDANT; AUTACOID; NITRIC OXIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; EX VIVO STUDY; FLOW CYTOMETRY; MICROVASCULATURE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROCEDURES; PROTEIN EXPRESSION; SEPSIS; THROMBOCYTE; THROMBOCYTE ADHESION; THROMBOCYTE AGGREGATION; ANIMAL; BIOLOGICAL MODEL; BIOSYNTHESIS; DRUG EFFECTS; GENE EXPRESSION REGULATION; METABOLISM;

ANIMALS; ANTIOXIDANTS; ASCORBIC ACID; GENE EXPRESSION REGULATION; INFLAMMATION MEDIATORS; MICE; MODELS, BIOLOGICAL; NITRIC OXIDE; P-SELECTIN; PLATELET AGGREGATION; SEPSIS;

EID: 84881526461     PISSN: 10739688     EISSN: 15498719     Source Type: Journal    
DOI: 10.1111/micc.12047     Document Type: Article

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