Hypertonicity compromises renal mineralocorticoid receptor signaling through Tis11b-mediated post-transcriptional control

Journal of the American Society of Nephrology

Volumn 25, Issue 10, 2014, Pages 2213-2221

  Viengchareun, Say ^a,b   Lema, Ingrid ^a,b   Lamribet, Khadija ^a,c,d   Keo, Vixra ^a,b   Blanchard, Anne ^a   Cherradi, Nadia ^a,c,d   Lombès, Marc ^a,b,e  

^a INSERM   (France)

^b UNIVERSITÉ PARIS SACLAY   (France)

^c CEA GRENOBLE   (France)

^d UNIV GRENOBLE ALPES   (France)

^e BICÊTRE HOSPITAL   (France)

Author keywords

[No Author keywords available]

Indexed keywords

BUTYRATE RESPONSE FACTOR 1; HYPERTONIC SOLUTION; LEUCINE ZIPPER PROTEIN; LUCIFERASE; MESSENGER RNA; MINERALOCORTICOID RECEPTOR; SMALL INTERFERING RNA; SODIUM CHANNEL; WATER; 3' UNTRANSLATED REGION; NUCLEAR PROTEIN; RNA BINDING PROTEIN; SODIUM; ZFP36L1 PROTEIN, HUMAN; ZFP36L1 PROTEIN, MOUSE;

3' UNTRANSLATED REGION; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; AU RICH ELEMENT; CELL STRESS; CONTROLLED STUDY; GENE EXPRESSION; GENE REPRESSION; GENETIC TRANSCRIPTION; GENETIC TRANSFECTION; HALF LIFE TIME; HUMAN; HUMAN CELL; HYPEROSMOTIC STRESS; IMMUNOPRECIPITATION; KIDNEY; KIDNEY CORTEX; KIDNEY DISTAL TUBULE; KIDNEY PROXIMAL TUBULE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN MOTIF; REPORTER GENE; SIGNAL TRANSDUCTION; SITE DIRECTED MUTAGENESIS; WATER DEPRIVATION; WESTERN BLOTTING; WILD TYPE; ANIMAL; HEK293 CELL LINE; METABOLIC DISORDER; METABOLISM; RNA PROCESSING;

3' UNTRANSLATED REGIONS; ANIMALS; BUTYRATE RESPONSE FACTOR 1; HEK293 CELLS; HUMANS; KIDNEY; MICE; NUCLEAR PROTEINS; RECEPTORS, MINERALOCORTICOID; RNA PROCESSING, POST-TRANSCRIPTIONAL; RNA-BINDING PROTEINS; SODIUM; WATER DEPRIVATION; WATER-ELECTROLYTE IMBALANCE;

EID: 84921712019     PISSN: 10466673     EISSN: 15333450     Source Type: Journal    
DOI: 10.1681/ASN.2013091023     Document Type: Article

References (26)

1. Viengchareun S, Le Menuet D, Martinerie L, Munier M, Pascual-Le Tallec L, Lombès M: The mineralocorticoid receptor: Insights into its molecular and (patho)physiological biology. Nucl Recept Signal 5: e012, 2007
2. Canessa CM, Schild L, Buell G, Thorens B, Gautschi I, Horisberger JD, Rossier BC: Amiloride-sensitive epithelial Na+ channel is made of three homologous subunits. Nature 367: 463-467, 1994
3. Verrey F: Transcriptional control of sodium transport in tight epithelial by adrenal steroids. J Membr Biol 144: 93-110, 1995
4. Bhalla V, Soundararajan R, Pao AC, Li H, Pearce D: Disinhibitory pathways for control of sodium transport: Regulation of ENaC by SGK1 and GILZ. Am J Physiol Renal Physiol 291: F714-F721, 2006
5. Quinkler M, Zehnder D, Eardley KS, Lepenies J, Howie AJ, Hughes SV, Cockwell P, Hewison M, Stewart PM: Increased expression of mineral-ocorticoid effector mechanisms in kidney biopsies of patients with heavy proteinuria. Circulation 112: 1435-1443, 2005
6. Shibata S, Nagase M, Yoshida S, Kawarazaki W, Kurihara H, Tanaka H, Miyoshi J, Takai Y, Fujita T: Modification of mineralocorticoid receptor function by Rac1GTPase: Implication in proteinuric kidney disease. Nat Med 14: 1370-1376, 2008
7. Martinerie L, Viengchareun S, Delezoide AL, Jaubert F, Sinico M, Prevot S, Boileau P, Meduri G, Lombès M: Low renal mineralocorticoid receptor expression at birth contributes to partial aldosterone resistance in neonates. Endocrinology 150: 4414-4424, 2009
8. Geller DS, Zhang J, Zennaro MC, Vallo-Boado A, Rodriguez-Soriano J, Furu L, Haws R, Metzger D, Botelho B, Karaviti L, Haqq AM, Corey H, Janssens S, Corvol P, Lifton RP: Autosomal dominant pseudohypoaldosteronism type 1: Mechanisms, evidence for neonatal lethality, and phenotypic expression in adults. J Am Soc Nephrol 17: 1429-1436, 2006
9. Wang X, Skelley L, Cade R, Sun Z: AAV delivery of mineralocorticoid receptor shRNA prevents progression of cold-induced hypertension and attenuates renal damage. Gene Ther 13: 1097-1103, 2006
10. Zennaro MC, Le Menuet D, Lombès M: Characterization of the human mineralocorticoid receptor gene 5′-regulatory region: Evidence for differential hormonal regulation of two alternative promoters via nonclassical mechanisms. Mol Endocrinol 10: 1549-1560, 1996
11. Pascual-Le Tallec L, Lombès M: The mineralocorticoid receptor: A journey exploring its diversity and specificity of action. Mol Endocrinol 19: 2211-2221, 2005
12. Faresse N, Vitagliano JJ, Staub O: Differential ubiquitylation of the mineralocorticoid receptor is regulated by phosphorylation. FASEB J 26: 4373-4382, 2012
13. Fenton RA, Knepper MA: Mouse models and the urinary concentrating mechanism in the new millennium. Physiol Rev 87: 1083-1112, 2007
14. 3H] aldosterone binding in rabbit tubules. Am J Physiol 241: F605-F611, 1981
15. Miyakawa H, Woo SK, Dahl SC, Handler JS, Kwon HM: Tonicity-responsive enhancer binding protein, a rel-like protein that stimulates transcription in response to hypertonicity. Proc Natl Acad Sci U S A 96: 2538-2542, 1999
16. Burg MB, Ferraris JD, Dmitrieva NI: Cellular response to hyperosmotic stresses. Physiol Rev 87: 1441-1474, 2007
17. Viengchareun S, Kamenicky P, Teixeira M, Butlen D, Meduri G, Blanchard-Gutton N, Kurschat C, Lanel A, Martinerie L, Sztal-Mazer S, Blot-Chabaud M, Ferrary E, Cherradi N, Lombès M: Osmotic stress regulates mineralocorticoid receptor expression in a novel aldosterone-sensitive cortical collecting duct cell line. Mol Endocrinol 23: 1948-1962, 2009
18. Blackshear PJ: Tristetraprolin and other CCCH tandem zinc-finger proteins in the regulation of mRNA turnover. Biochem Soc Trans 30: 945-952, 2002
19. Duan H, Cherradi N, Feige JJ, Jefcoate C: cAMP-dependent post-transcriptional regulation of steroidogenic acute regulatory (STAR) protein by the zinc finger protein ZFP36L1/TIS11b. Mol Endocrinol 23: 497-509, 2009
20. Chen S, Grigsby CL, Law CS, Ni X, Nekrep N, Olsen K, Humphreys MH, Gardner DG: Tonicity-dependent induction of Sgk1 expression has a potential role in dehydration-induced natriuresis in rodents. J Clin Invest 119: 1647-1658, 2009
21. Ciais D, Cherradi N, Bailly S, Grenier E, Berra E, Pouyssegur J, Lamarre J, Feige JJ: Destabilization of vascular endothelial growth factor mRNA by the zinc-finger protein TIS11b. Oncogene 23: 8673-8680, 2004
22. Schaaf MJ, Cidlowski JA: AUUUA motifs in the 3′UTR of human glucocorticoid receptor alpha and beta mRNA destabilize mRNA and decrease receptor protein expression. Steroids 67: 627-636, 2002
23. Kenealy MR, Flouriot G, Sonntag-Buck V, Dandekar T, Brand H, Gannon F: The 3′-untranslated region of the human estrogen receptor alpha gene mediates rapid messenger ribonucleic acid turnover. Endocrinology 141: 2805-2813, 2000
24. Cherradi N, Lejczak C, Desroches-Castan A, Feige JJ: Antagonistic functions of tetradecanoyl phorbol acetate-inducible-sequence 11b and HuR in the hormonal regulation of vascular endothelial growth factor messenger ribonucleic acid stability by adrenocorticotropin. Mol Endocrinol 20: 916-930, 2006
25. Chamboredon S, Ciais D, Desroches-Castan A, Savi P, Bono F, Feige JJ, Cherradi N: Hypoxia-inducible factor-1α mRNA: A new target for destabilization by tristetraprolin in endothelial cells. Mol Biol Cell 22: 3366-3378, 2011
26. Planel S, Salomon A, Jalinot P, Feige JJ, Cherradi N: A novel concept in antiangiogenic and antitumoral therapy: Multitarget destabilization of short-lived mRNAs by the zinc finger protein ZFP36L1. Oncogene 29: 5989-6003, 2010